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index medicus (7) 7
cystic fibrosis (6) 6
humans (6) 6
respiratory system (6) 6
female (5) 5
infants (5) 5
bronchoalveolar lavage (4) 4
children (4) 4
infant (4) 4
infant, newborn (4) 4
infection (4) 4
male (4) 4
young-children (4) 4
cystic fibrosis - complications (3) 3
cystic fibrosis - diagnosis (3) 3
inflammation (3) 3
medical screening (3) 3
neonatal screening (3) 3
outcomes (3) 3
pseudomonas aeruginosa (3) 3
tomography, x-ray computed (3) 3
abridged index medicus (2) 2
analysis (2) 2
bacteriophage (2) 2
bronchiectasis (2) 2
cell count (2) 2
child, preschool (2) 2
children & youth (2) 2
children's hospitals (2) 2
childrens health (2) 2
critical care medicine (2) 2
cystic fibrosis - physiopathology (2) 2
diagnosis (2) 2
diagnostic imaging (2) 2
disease (2) 2
epithelial cells (2) 2
fibrosis (2) 2
health aspects (2) 2
hospitals (2) 2
lung (2) 2
medicine (2) 2
multidisciplinary sciences (2) 2
neutrophil elastase (2) 2
phage therapy (2) 2
pharmacology (2) 2
resolution computed-tomography (2) 2
respiratory function tests (2) 2
respiratory tract (2) 2
respiratory tract infections - complications (2) 2
screening (2) 2
usage (2) 2
air (1) 1
airway (1) 1
airway epithelial cells (1) 1
airway function (1) 1
alveoli (1) 1
anatomy (1) 1
animal cells (1) 1
antimicrobial (1) 1
aspergillosis (1) 1
assaying (1) 1
association (1) 1
australia (1) 1
autosomal recessive diseases (1) 1
b-cell receptor (1) 1
babies (1) 1
bacteria (1) 1
biochemistry (1) 1
biofilms (1) 1
biological cultures (1) 1
biological tissue (1) 1
biology and life sciences (1) 1
bronchiectasis - diagnostic imaging (1) 1
bronchiectasis - etiology (1) 1
bronchoalveolar lavage - adverse effects (1) 1
bronchoalveolar lavage fluid - cytology (1) 1
bronchoscopy (1) 1
bronchus (1) 1
burden (1) 1
care and treatment (1) 1
case-control studies (1) 1
cc chemokines (1) 1
cell biology (1) 1
cells (1) 1
cellular types (1) 1
cftr expression (1) 1
channel gating (1) 1
chemical compounds (1) 1
chemistry (1) 1
chemokine ccl2 - metabolism (1) 1
chemokine ccl5 - metabolism (1) 1
chest (1) 1
chest computed tomography scans (1) 1
child (1) 1
chloride (1) 1
clearance (1) 1
clinical genetics (1) 1
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1. Full Text Lung Disease at Diagnosis in Infants with Cystic Fibrosis Detected by Newborn Screening
by Sly, Peter D and Brennan, Siobhain and Gangell, Catherine and de Klerk, Nicholas and Murray, Conor and Mott, Lauren and Stick, Stephen M and Robinson, Philip J and Robertson, Colin F and Ranganathan, Sarath C and on behalf of Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST-CF) and AREST-CF and Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST-CF)
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2009, Volume 180, Issue 2, pp. 146 - 152
Rationale The promise of newborn screening (NIBS) for cystic fibrosis (CF) has not been fully realized, and the extent of improvement in respiratory outcomes... 
Pulmonary inflammation | Neutrophil elastase | Chest computed tomography scans | Bronchoalveolar lavage | Pulmonary infection | pulmonary infection | RESOLUTION COMPUTED-TOMOGRAPHY | RESPIRATORY SYSTEM | neutrophil elastase | pulmonary inflammation | INFECTION | OUTCOMES | chest computed tomography scans | bronchoalveolar lavage | YOUNG-CHILDREN | LOWER AIRWAY INFLAMMATION | CRITICAL CARE MEDICINE | Pneumonia - epidemiology | Cystic Fibrosis - physiopathology | Humans | Bronchoalveolar Lavage | Infant | Male | Tomography, X-Ray Computed | Pneumonia - microbiology | Cystic Fibrosis - complications | Neonatal Screening | Respiratory Tract Infections - diagnosis | Respiration Disorders - microbiology | Pneumonia - diagnosis | Respiration Disorders - diagnosis | Cystic Fibrosis - diagnosis | Female | Respiratory Tract Infections - complications | Respiratory Function Tests | Respiratory Tract Infections - epidemiology | Australia | Population Surveillance | Respiration Disorders - epidemiology | Infant, Newborn | Cohort Studies
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2. Full Text Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells
by Sutanto, Erika N and Scaffidi, Amelia and Garratt, Luke W and Looi, Kevin and Foo, Clara J and Tessari, Michela A and Janssen, Richard A and Fischer, David F and Stick, Stephen M and Kicic, Anthony and AREST CF and on behalf of AREST CF
PLoS ONE, ISSN 1932-6203, 01/2018, Volume 13, Issue 1, p. e0191618
Background & para;& para;Mutations in the cystic fibrosis transmembrane regulator (CFTR) gene can reduce function of the CFTR ion channel activity and impair... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | PLURIPOTENT STEM-CELLS | SENSITIVE FLUORESCENT INDICATORS | LUNG | PROTEIN | CFTR EXPRESSION | MULTIDISCIPLINARY SCIENCES | TRAFFICKING | GENERATION | SMALL-MOLECULE CORRECTORS | CHLORIDE | Pediatrics | Epithelial cells | Genistein | Childrens health | Fluorescence | High-throughput screening | Assaying | B-cell receptor | Seeding | Proteins | Respiratory tract | Chloride | Reporter gene | Restoration | Rodents | Ion channels | Children | Yellow fluorescent protein | Iodides | Secretion | Channel gating | Ion transport | Cystic fibrosis | Cultures | Data processing | Pharmacology | Medical screening | Chemical compounds | Patients | Media (transport) | Children & youth | Medicine | Studies | Screening | Syntaxin | Hospitals | Lymphocytes B | Fibrosis | Stem cells | Forskolin | Mutation | Cystic fibrosis transmembrane conductance regulator
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3. Full Text Lung Function in Infants with Cystic Fibrosis Diagnosed by Newborn Screening
by Linnane, Barry M and Hall, Graham L and Nolan, Gary and Brennan, Siobhan and Stick, Stephen M and Sly, Peter D and Robertson, Colin F and Robinson, Philip J and Franklin, Peter J and Turner, Stephen W and Ranganathan, Sarath C and on behalf of Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST-CF) and AREST CF and AREST-CF
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 12/2008, Volume 178, Issue 12, pp. 1238 - 1244
Rationale: Progressive lung damage in cystic fibrosis (CF) starts in infancy, and early detection may aid preventative strategies. Objectives: To measure lung... 
RESPIRATORY SYSTEM | CLINICAL-DIAGNOSIS | INFLAMMATION | VOLUME FORCED EXPIRATION | DISEASE | GROWTH | INFECTION | AIRWAY FUNCTION | OUTCOMES | ASSOCIATION | YOUNG-CHILDREN | CRITICAL CARE MEDICINE | Bronchoscopy | Severity of Illness Index | Prognosis | Forced Expiratory Volume - physiology | Cell Count | Cystic Fibrosis - physiopathology | Humans | Child, Preschool | Infant | Male | Mass Screening - methods | Vital Capacity - physiology | Cystic Fibrosis - diagnosis | Female | Bronchoalveolar Lavage Fluid - cytology | Infant, Newborn
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4. Full Text Use of a primary epithelial cell screening tool to investigate phage therapy in cystic fibrosis
by Trend, Stephanie and Chang, Barbara J and O'Dea, Mark and Stick, Stephen M and Kicic, Anthony and AREST CF and AusREC and WAERP
Frontiers in Pharmacology, ISSN 1663-9812, 11/2018, Volume 9, p. 1330
Antimicrobial-resistant microbes are an increasing threat to human health. In cystic fibrosis (CF), airway infections with Pseudomonas aeruginosa remain a key... 
Infection | Cystic fibrosis | Pseudomonas aeruginosa | Airway epithelial cells | Preclinical models | Phage therapy | preclinical models | infection | BACTERIOPHAGE | EFFICACY | airway epithelial cells | BIOFILMS | CHILDREN | DELIVERY | AIRWAY | cystic fibrosis | PSEUDOMONAS-AERUGINOSA | INFLAMMATION | phage therapy | INFANTS | PHARMACOLOGY & PHARMACY | Care and treatment | Usage | Epithelial cells | Analysis | Diagnosis | Research | Children | Medical screening | Health aspects
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5. Full Text Air trapping on chest CT is associated with worse ventilation distribution in infants with cystic fibrosis diagnosed following newborn screening
by Hall, Graham L and Logie, Karla M and Parsons, Faith and Schulzke, Sven M and Nolan, Gary and Murray, Conor and Ranganathan, Sarath and Robinson, Phil and Sly, Peter D and Stick, Stephen M and AREST CF and on behalf of AREST CF
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23932
Background: In school-aged children with cystic fibrosis (CF) structural lung damage assessed using chest CT is associated with abnormal ventilation... 
INERT-GAS WASHOUT | HEALTHY INFANTS | RESOLUTION COMPUTED-TOMOGRAPHY | MULTIDISCIPLINARY SCIENCES | VOLUME | MULTIPLE-BREATH WASHOUT | LUNG-DISEASE | ULTRASONIC FLOW METER | CHILDREN | Lung Injury - pathology | Humans | Infant | Male | Tomography, X-Ray Computed | Air | Neonatal Screening | Cystic Fibrosis - diagnostic imaging | Lung Injury - etiology | Bronchoalveolar Lavage - adverse effects | Cystic Fibrosis - diagnosis | Female | Ventilation | Radiography, Thoracic | Retrospective Studies | Respiratory Function Tests | Child | Infant, Newborn | Infants (Newborn) | CT imaging | Cystic fibrosis | Diagnostic imaging | Chest | Respiratory function | Childrens health | Infants | Respiratory tract | Computed tomography | Newborn babies | Bronchoalveolar lavage | Children | Alveoli | Drug dosages | Medical research | Task forces | Damage assessment | Statistical analysis | Medical imaging | Lung diseases | Bronchus | Bronchiectasis | Medical screening | Children & youth | Medicine | Babies | Pathology | Screening | Trapping | Hospitals | Preschool children | Surveillance | Structural damage | Fibrosis
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6. Full Text Bronchiectasis in an asymptomatic infant with cystic fibrosis diagnosed following newborn screening
by Mott, Lauren S and Gangell, Catherine L and Murray, Conor P and Stick, Stephen M and Sly, Peter D and on behalf of AREST CF and AREST CF
Journal of Cystic Fibrosis, ISSN 1569-1993, 2009, Volume 8, Issue 4, pp. 285 - 287
Abstract Many countries have introduced newborn screening for cystic fibrosis to facilitate diagnosis prior to the development of lung disease. Although most... 
Pulmonary/Respiratory | Cystic fibrosis | Pseudomonas aeruginosa | Diagnostic imaging | Bronchoalveolar lavage | RESPIRATORY SYSTEM | DISEASE | OUTCOMES | YOUNG-CHILDREN | OROPHARYNGEAL CULTURES | Humans | Bronchiectasis - diagnostic imaging | Bronchoalveolar Lavage | Pseudomonas Infections - complications | Female | Tomography, X-Ray Computed | Cystic Fibrosis - complications | Neonatal Screening | Infant, Newborn | Bronchiectasis - etiology | Infants (Newborn) | Children's hospitals | Respiratory agents | Bronchiectasis | Diagnosis
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7. Alveolar macrophages and CC chemokines are increased in children with cystic fibrosis
by Brennan, S and Sly, P.D and Gangell, C.L and Sturges, N and Winfield, K and Wikstrom, M and Gard, S and Upham, J.W and AREST CF
European Respiratory Journal, ISSN 0903-1936, 09/2009, Volume 34, Issue 3, pp. 655 - 661
Airway inflammation is an important component of cystic fibrosis (CF) lung disease. We sought to determine whether alveolar macrophages were involved in early... 
Cystic fibrosis | Children | CC chemokines | Macrophages | EARLY PULMONARY INFLAMMATION | LUNG | CELLS | CLEARANCE | RESOLUTION | NEUTROPHIL ELASTASE | ASPERGILLOSIS | macrophages | children | RESPIRATORY SYSTEM | cystic fibrosis | INFANTS | EXPRESSION | YOUNG-CHILDREN | Lung - pathology | Respiratory Tract Infections - metabolism | Cystic Fibrosis - metabolism | Cystic Fibrosis - microbiology | Cell Count | Humans | Macrophage Inflammatory Proteins - metabolism | Cystic Fibrosis - pathology | Bronchoalveolar Lavage | Child, Preschool | Macrophages, Alveolar - physiology | Infant | Male | Case-Control Studies | Female | Chemokine CCL2 - metabolism | Chemokine CCL5 - metabolism | Lung - metabolism | Respiratory Tract Infections - complications | Respiratory Tract Infections - pathology
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8. Full Text The potential of phage therapy in cystic fibrosis: Essential human-bacterial-phage interactions and delivery considerations for use in Pseudomonas aeruginosa-infected airways
by Trend, Stephanie and Fonceca, Angela M and Ditcham, William G and Kicic, Anthony and CF, AREST and AREST CF
Journal of Cystic Fibrosis, ISSN 1569-1993, 11/2017, Volume 16, Issue 6, pp. 663 - 670
As antimicrobial-resistant microbes become increasingly common and a significant global issue, novel approaches to treating these infections particularly in... 
Infection | Antimicrobial | Cystic fibrosis | Pseudomonas aeruginosa | Bacteriophage | Phage therapy | SYSTEM | GENOTYPES | RESPONSES | MORBIDITY | RESPIRATORY SYSTEM | INFLAMMATION | INFANTS | RESISTANCE | BURDEN | STRAIN | CLINICAL-OUTCOMES | Respiratory Tract Infections - microbiology | Pseudomonas Infections - etiology | Respiratory Tract Infections - therapy | Humans | Pseudomonas Infections - therapy | Pseudomonas aeruginosa - physiology | Phage Therapy - methods | Cystic Fibrosis - complications | Drug Delivery Systems | Medical colleges | Drug resistance in microorganisms | Usage | Analysis | Children's hospitals | Bacteria | Health aspects
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