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Toxicology and Applied Pharmacology, ISSN 0041-008X, 08/2012, Volume 262, Issue 3, pp. 265 - 272
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 06/2011, Volume 253, Issue 3, pp. 261 - 269
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2014, Volume 281, Issue 3, pp. 285 - 293
Beta-lapachone (beta-Lp) derived from the Lapacho tree is a potentially novel anticancer agent currently under clinical trials. Previous studies suggested that... 
NQO1 | Beta-lapachone | EPR | Mitochondrial electron transport chain | ROS | Cancer cells | ANION-RADICAL PRODUCTION | OXYGEN SPECIES PRODUCTION | OXIDATIVE STRESS | SUPEROXIDE | B16-F10 MELANOMA | THERAPY | OXIDASE | BIS-N-METHYLACRIDINIUM | LUCIGENIN | SYSTEMS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Neoplasms - metabolism | Mitochondria - enzymology | Reactive Oxygen Species - metabolism | Humans | Reverse Transcriptase Inhibitors - pharmacology | Neoplasm Proteins - antagonists & inhibitors | Prodrugs - chemistry | Neoplasm Proteins - metabolism | Electron Transport Complex I - metabolism | Prodrugs - metabolism | Reverse Transcriptase Inhibitors - chemistry | Antineoplastic Agents, Phytogenic - antagonists & inhibitors | Oxidation-Reduction - drug effects | Rotenone - pharmacology | Activation, Metabolic - drug effects | Antineoplastic Agents, Phytogenic - metabolism | Electron Transport Complex I - antagonists & inhibitors | Naphthoquinones - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Indolequinones - pharmacology | Neoplasms - enzymology | Naphthoquinones - pharmacology | Mitochondria - metabolism | Mitochondria - drug effects | NAD(P)H Dehydrogenase (Quinone) - antagonists & inhibitors | Neoplasms - drug therapy | Animals | Cell Line, Tumor | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | Reverse Transcriptase Inhibitors - metabolism | Antineoplastic Agents, Phytogenic - pharmacology | Naphthoquinones - metabolism | Prodrugs - pharmacology | Antimitotic agents | Oncology, Experimental | Melanoma | Mitochondrial DNA | Research | Antineoplastic agents | Cancer | ELECTRON SPIN RESONANCE | SUPEROXIDE DISMUTASE | HEPATOMAS | CLINICAL TRIALS | CHEMILUMINESCENCE | MITOCHONDRIA | MELANOMAS | BENZOQUINONES | 60 APPLIED LIFE SCIENCES | OXYGEN | CELL KILLING | PHOSPHATES | RADICALS | OXIDES | PEROXIDASES
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 06/2014, Volume 277, Issue 3, pp. 279 - 287
Journal Article
Experimental Cell Research, ISSN 0014-4827, 03/2016, Volume 342, Issue 1, pp. 52 - 61
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2012, Volume 426, Issue 1, pp. 26 - 32
► Estrogen signaling and demethylation can both control gene expression in breast cancers. ► Cross-talk between these mechanisms is investigated in human MCF-7... 
DNA methylation | Estrogen receptor | 5-Aza-2′-deoxycytidine | Breast cancer | Microarray | Estrogen | 5-Aza-2'-deoxycytidine | BTG3 | 5-Aza-2 '-deoxycytidine | HUMAN-DISEASE | HYPERMETHYLATION | ANTIESTROGENS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | GENISTEIN | DNA METHYLATION PROFILES | EPIGENETICS | BIOPHYSICS | BIOLOGY | EXPRESSION | Estradiol - metabolism | Promoter Regions, Genetic | Estrogens - pharmacology | Signal Transduction | DNA Modification Methylases - antagonists & inhibitors | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Azacitidine - analogs & derivatives | Proteins - genetics | Azacitidine - pharmacology | Breast Neoplasms - genetics | Cell Line, Tumor | Female | LIM Domain Proteins - genetics | Estrogens - metabolism | DNA Methylation - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Estradiol - pharmacology | Care and treatment | DNA microarrays | Genes | Cancer cells | Phenols | Genetic research | Genetic aspects | Methylation | Gene expression | Estradiol | Cancer | Cell proliferation | FHL2 protein | Gene regulation | Estrogen receptors | Data processing | Intracellular signalling | Tamoxifen | BTG2 protein | 17 beta -Estradiol | Promoters | epigenetics | Demethylation | Gene silencing | Signal transduction | 5-aza-2'-deoxycytidine | Apoptosis | CpG islands | APOPTOSIS | METHYLATION | MAMMARY GLANDS | NEOPLASMS | TAMOXIFEN | CELL PROLIFERATION | 60 APPLIED LIFE SCIENCES | DOSES | PROMOTERS | DNA | DEOXYCYTIDINE | ESTRADIOL | GENES | RECEPTORS
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2011, Volume 405, Issue 4, pp. 575 - 580
Journal Article
Journal Article