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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 85, Issue 5, pp. 1186 - 1192
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 11/2015, Volume 288, Issue 3, pp. 359 - 373
Gefitinib is the first-line chemotherapeutic drug for treating non-small cell lung cancer (NSCLC), which comprises nearly 85% of all lung cancer cases... 
Resistance | DIGE | Proteomics | Lung adenocarcinoma | Gefitinib | PCNT | mPR | CELLS | NSCLC | BREAST-CANCER | THERAPY | GROWTH | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PROTEOMIC ANALYSIS | CONTRIBUTES | UTERINE-CANCER | Lung Neoplasms - drug therapy | RNA, Small Interfering - genetics | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | ErbB Receptors - genetics | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Cell Line, Tumor - drug effects | Receptors, Progesterone - genetics | Receptors, Progesterone - metabolism | Adenocarcinoma - metabolism | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Proteomics - methods | Carcinoma, Non-Small-Cell Lung - pathology | Cell Survival - drug effects | ErbB Receptors - metabolism | Signal Transduction | Membrane Proteins - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Gene Silencing | Antigens - metabolism | Quinazolines - pharmacology | Antigens - genetics | RNA, Small Interfering - metabolism | Adenocarcinoma | Proteins | Chemotherapy | Hormones, Sex | Drug resistance | Lung cancer, Non-small cell | Cancer | Index Medicus | LASERS | GELS | PROGESTERONE | RNA | LUNGS | MASS SPECTROSCOPY | 60 APPLIED LIFE SCIENCES | DESORPTION | ELECTROPHORESIS | BIOLOGICAL MARKERS | DRUGS | CARCINOMAS | RECEPTORS | IONIZATION
Journal Article
Clinical Immunology, ISSN 1521-6616, 2006, Volume 123, pp. S112 - S113
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 05/2012, Volume 261, Issue 1, pp. 105 - 115
The induction of matrix metalloproteinase (MMP)-9 is particularly important for the invasiveness of various cancer cells. Osthole, a natural coumarin... 
NF-κB | Lung adenocarcinoma | Osthole | Migration | Invasion | MMPs | MMP-9 EXPRESSION | METASTASIS | MATRIX-METALLOPROTEINASE EXPRESSION | CNIDIUM-MONNIERI | BREAST-CANCER CELLS | NF-kappa B | ISOPENTENYLATED COUMARINS | PATHWAY | PROSTATE-CANCER | GROWTH | PHARMACOLOGY & PHARMACY | TOXICOLOGY | REGULATORY MECHANISM | Lung Neoplasms - drug therapy | Promoter Regions, Genetic | Adenocarcinoma - pathology | Medicine, Chinese Traditional | Matrix Metalloproteinase 2 - metabolism | Neoplasm Invasiveness | Humans | Lung Neoplasms - pathology | NF-kappa B - metabolism | RNA, Messenger - metabolism | Adenocarcinoma - drug therapy | Coumarins - pharmacology | Cell Movement - drug effects | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Fluorescent Antibody Technique | Cell Line, Tumor | Gene Expression Regulation, Neoplastic - drug effects | Binding Sites | NF-kappa B - drug effects | Index Medicus | Adenocarcinoma | Cell proliferation | Immunoprecipitation | Invasiveness | Tumor cells | Lung cancer | Matrix metalloproteinase | Tumor cell lines | Gene expression | Coumarin | Gelatinase B | Nuclear transport | Promoters | Western blotting | Gelatinase A | Traditional Chinese Medicine | NF- Kappa B protein | Proteolysis | Cell migration | TRANSLOCATION | CHROMATIN | LUNGS | METASTASES | TUMOR CELLS | 60 APPLIED LIFE SCIENCES | MUTANTS | INHIBITION | FLUORESCENCE | MESSENGER-RNA | PROMOTERS | DNA | CARCINOMAS | COUMARIN | PROTEINS
Journal Article
Dokkyo journal of medical sciences, ISSN 0385-5023, 03/2013, Volume 40, Issue 1, pp. 55 - 59
The use of antibodies against epidermal growth factor receptor( EGFR) in conjunction with conventionalchemotherapy for metastatic colorectal cancer (CRC) in... 
KRAS mutation | Colorectal cancer | Pyrosequencing
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2014, Volume 90, Issue 1, pp. 224 - 230
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2014, Volume 279, Issue 2, pp. 95 - 102
A recent study demonstrated that an increased risk of chronic kidney disease (CKD) was associated with high urinary total arsenic levels. However, whether... 
Aldosterone synthase (CYP11B2) | Gene polymorphisms | Chronic kidney disease | Arsenic | Renin–angiotensin–aldosterone system | Angiotensinogen (AGT) | Renin-angiotensin-aldosterone system | II TYPE-1 RECEPTOR | SYNTHASE GENE | RISK | DIFFERENTIAL REGULATION | ALL-CAUSE MORTALITY | DIABETES-MELLITUS | COMMUNITY-BASED POPULATION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | DRINKING-WATER | ASSOCIATION | CONVERTING-ENZYME | Multivariate Analysis | Biomarkers - urine | Humans | Middle Aged | Male | Chromatography, High Pressure Liquid | Case-Control Studies | Peptidyl-Dipeptidase A - genetics | Receptor, Angiotensin, Type 1 - genetics | Renal Insufficiency, Chronic - genetics | Female | Odds Ratio | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Logistic Models | Renin-Angiotensin System - genetics | Chi-Square Distribution | Linkage Disequilibrium | Polymorphism, Genetic | Spectrophotometry, Atomic | Angiotensinogen - genetics | Phenotype | Arsenic - urine | Taiwan | Arsenic - adverse effects | Aged | Renal Insufficiency, Chronic - chemically induced | Cytochrome P-450 CYP11B2 - genetics | Renal Insufficiency, Chronic - urine | Corticosteroids | Chronic kidney failure | Cytochrome P-450 | Angiotensin | Genetic research | Genetic aspects | Aldosterone | Genetic polymorphisms | Steroids | Index Medicus | PATIENTS | RENIN | GENOTYPE | HYDRIDES | ABSORPTION SPECTROSCOPY | HOSPITALS | 60 APPLIED LIFE SCIENCES | ANGIOTENSIN | CONCENTRATION RATIO | KIDNEYS | ARSENIC | HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY | POLYMERASE CHAIN REACTION | GENES | ALDOSTERONE | HYPERTENSION | RECEPTORS | HAZARDS
Journal Article
Dokkyo journal of medical sciences, ISSN 0385-5023, 03/2015, Volume 42, Issue 1, pp. 21 - 29
Background:Amantadine is a drug used for patients with Parkinson's disease (PD) and vascular parkinsonism (VP). These patients often have lower urinary tract... 
Lower urinary tract dysfunction | Nocturnal polyuria | Amantadine | Vascular parkinsonism | Parkinson’s disease
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 01/2013, Volume 266, Issue 2, pp. 298 - 306
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 11/2014, Volume 281, Issue 1, pp. 39 - 47
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2006, Volume 340, Issue 1, pp. 221 - 227
Acetaldehyde, an inhibitor of mitochondrial function, has been widely used as a neurotoxin because it elicits a severe Parkinson’s disease-like syndrome with... 
Rosiglitazone | Parkinson’s disease | PPAR-γ | ROS | Acetaldehyde | Apoptosis | Parkinson's disease | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY