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hemic and lymphatic diseases (2) 2
humans (2) 2
index medicus (2) 2
receptor protein-tyrosine kinases - genetics (2) 2
abnormalities (1) 1
activation (1) 1
alk (1) 1
alk fusion (1) 1
anaplastic lymphoma (1) 1
anaplastic lymphoma kinase (1) 1
antineoplastic agents - pharmacology (1) 1
cell transformation, neoplastic - genetics (1) 1
eml4-alk fusion gene (1) 1
endocrinology & metabolism (1) 1
expression (1) 1
gene (1) 1
growth-factor (1) 1
heavy-chain gene (1) 1
hematology (1) 1
identification (1) 1
inflammatory myofibroblastic tumor (1) 1
intracellular signaling peptides and proteins - metabolism (1) 1
kinase inhibitors (1) 1
large-cell lymphoma (1) 1
lymphoid differentiation (1) 1
lymphoma - genetics (1) 1
lymphoma - metabolism (1) 1
lymphoma, large-cell, anaplastic - genetics (1) 1
mouse (1) 1
mouse models (1) 1
mutation (1) 1
neoplasms - genetics (1) 1
neoplasms - metabolism (1) 1
non-hodgkins-lymphoma (1) 1
npm-alk (1) 1
peripheral t-cell (1) 1
phosphatidylinositol 3-kinases - metabolism (1) 1
phospholipase c gamma - metabolism (1) 1
piperidines - pharmacology (1) 1
protein-tyrosine kinases - metabolism (1) 1
proto-oncogene proteins - metabolism (1) 1
proto-oncogene proteins p21 - metabolism (1) 1
pyrazoles (1) 1
pyridines - pharmacology (1) 1
receptor protein-tyrosine kinases - antagonists & inhibitors (1) 1
receptor protein-tyrosine kinases - metabolism (1) 1
receptor protein-tyrosine kinases - physiology (1) 1
receptor tyrosine kinase (1) 1
recognition (1) 1
signal transduction (1) 1
signal transduction - physiology (1) 1
signalling pathways (1) 1
small-molecule inhibitor (1) 1
src-family kinases (1) 1
transcriptional activation (1) 1
translocation, genetic (1) 1
tyrosine kinase (1) 1
up-regulation - genetics (1) 1
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1. Anaplastic lymphoma kinase in human cancer
by Barreca, Antonella and Lasorsa, Elena and Riera, Ludovica and Machiorlatti, Rodolfo and Piva, Roberto and Ponzoni, Maurilio and Kwee, Ivo and Bertoni, Francesco and Piccaluga, Pier Paolo and Pileri, Stefano A and Inghirami, Giorgio and European T-Cell Lymphoma Study Grp and European T-Cell Lymphoma Study Group
Journal of Molecular Endocrinology, ISSN 0952-5041, 08/2011, Volume 47, Issue 1, pp. R11 - R23
The receptor tyrosine kinases (RTKs) play a critical role, controlling cell proliferation, survival, and differentiation of normal cells. Their pivotal... 
NPM-ALK | EML4-ALK FUSION GENE | HEAVY-CHAIN GENE | ENDOCRINOLOGY & METABOLISM | INFLAMMATORY MYOFIBROBLASTIC TUMOR | NON-HODGKINS-LYMPHOMA | ALK FUSION | LARGE-CELL LYMPHOMA | GROWTH-FACTOR | RECEPTOR TYROSINE KINASE | SMALL-MOLECULE INHIBITOR | Neoplasms - metabolism | Proto-Oncogene Proteins - metabolism | Translocation, Genetic | Phospholipase C gamma - metabolism | Signal Transduction | src-Family Kinases | Protein-Tyrosine Kinases - metabolism | Pyrazoles | Humans | Transcriptional Activation | Lymphoma - genetics | Up-Regulation - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Lymphoma - metabolism | Neoplasms - genetics | Piperidines - pharmacology | Receptor Protein-Tyrosine Kinases - genetics | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Pyridines - pharmacology | Mutation | Proto-Oncogene Proteins p21(ras) - metabolism
Journal Article
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2. Full Text Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma
by Tabbò, Fabrizio and Ponzoni, Maurilio and Rabadan, Raul and Bertoni, Francesco and Inghirami, Giorgio and European T-Cell Lymphoma Study Grp and European T-cell Lymphoma Study Group
Current Opinion in Hematology, ISSN 1065-6251, 07/2013, Volume 20, Issue 4, pp. 374 - 381
PURPOSE OF REVIEWAnaplastic large cell lymphomas (ALCLs) are rare entities whose somatic genetic lesions have been identified only in a subset of patients.... 
Signalling pathways | Lymphoid differentiation | Kinase inhibitors | Mouse models | Anaplastic lymphoma kinase | mouse models | ALK | ACTIVATION | RECOGNITION | ABNORMALITIES | TYROSINE KINASE | anaplastic lymphoma kinase | MOUSE | IDENTIFICATION | PERIPHERAL T-CELL | lymphoid differentiation | kinase inhibitors | signalling pathways | GENE | HEMATOLOGY | EXPRESSION | Signal Transduction - physiology | Receptor Protein-Tyrosine Kinases - genetics | Cell Transformation, Neoplastic - genetics | Humans | Receptor Protein-Tyrosine Kinases - physiology | Lymphoma, Large-Cell, Anaplastic - genetics
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