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1. Full Text Heme oxygenase-1 repeat polymorphism in septic acute kidney injury
by Vilander, Laura M and Vaara, Suvi T and Donner, Kati M and Lakkisto, Paivi and Kaunisto, Mari A and Pettila, Ville and FINNAKI Study Group and the FINNAKI Study Group
PLoS ONE, ISSN 1932-6203, 05/2019, Volume 14, Issue 5, pp. e0217291 - e0217291
Acute kidney injury (AKI) is a syndrome that frequently affects the critically ill. Recently, an increased number of dinucleotide repeats in the HMOX1 gene... 
Ethylenediaminetetraacetic acid | Medicine, Experimental | Enzymes | Medical research | Genetic aspects | Heme | Plasma | Intensive care | Kidneys | Thymine | Heme oxygenase (decyclizing) | Guanine | Medicine | Oxygenase | Hospitals | Pain | Rodents | Surgery | Classification | Alleles | Quality control | Sepsis | Internet | Genetic testing | Anesthesiology | Deoxyribonucleic acid--DNA | Polymorphism | Deoxyribonucleic acid | DNA
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2. Full Text Heparin-binding protein (HBP) improves prediction of sepsis-related acute kidney injury
by Tverring, Jonas and Vaara, Suvi T and Fisher, Jane and Poukkanen, Meri and Pettilä, Ville and Linder, Adam and FINNAKI Study Grp and FINNAKI Study Group and the FINNAKI Study Group and Lund University and Translationell Sepsisforskning and Translational Sepsis research and Infektionsmedicin and Lunds universitet and Division of Infection Medicine (BMC) and SEBRA Sepsis and Bacterial Resistance Alliance
Annals of Intensive Care, ISSN 2110-5820, 12/2017, Volume 7, Issue 1, pp. 1 - 10
Sepsis-related acute kidney injury (AKI) accounts for major morbidity and mortality among the critically ill. Heparin-binding protein (HBP) is a promising... 
Risk model | Biomarker | Emergency Medicine | Medicine & Public Health | Heparin-binding protein | Acute kidney injury | Intensive / Critical Care Medicine | Sepsis | Anesthesiology | MORTALITY | MULTICENTER | NEUTROPHILS | IDENTIFICATION | FAILURE | binding protein | INFLAMMATION | ORGAN DYSFUNCTION | Heparin | SECRETION | HBP/CAP37 | CRITICALLY-ILL PATIENTS | CRITICAL CARE MEDICINE | Plasma | Kidneys | Urologi och njurmedicin | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Urology and Nephrology
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3. Full Text Urinary biomarkers indicative of apoptosis and acute kidney injury in the critically ill
by Vaara, Suvi T and Lakkisto, Päivi and Immonen, Katariina and Tikkanen, Ilkka and Ala-Kokko, Tero and Pettilä, Ville and Laru-Sompa, Raili and Pulkkinen, Anni and Saarelainen, Minna and Reilama, Mikko and Tolmunen, Sinikka and Rantalainen, Ulla and Miettinen, Marja and Suvela, Markku and Pesola, Katrine and Saastamoinen, Pekka and Kauppinen, Sirpa and Kaukonen, Kirsi-Maija and Korhonen, Anna-Maija and Nisula, Sara and Suojaranta-Ylinen, Raili and Mildh, Leena and Haapio, Mikko and Nurminen, Laura and Sutinen, Sari and Pettilä, Leena and Laitinen, Helinä and Syrjä, Heidi and Henttonen, Kirsi and Lappi, Elina and Boman, Hillevi and Varpula, Tero and Porkka, Päivi and Sivula, Mirka and Rahkonen, Mira and Tsurkka, Anne and Nieminen, Taina and Pirttinen, Niina and Alaspää, Ari and Salanto, Ville and Juntunen, Hanna and Sanisalo, Teija and Parviainen, Ilkka and Uusaro, Ari and Ruokonen, Esko and Bendel, Stepani and Rissanen, Niina and Lång, Maarit and Rahikainen, Sari and Rissanen, Saija and Ahonen, Merja and Halonen, Elina and Vaskelainen, Eija and Poukkanen, Meri and Lintula, Esa and Suominen, Sirpa and Heikkinen, Jorma and Lavander, Timo and Heinonen, Kirsi and Juopperi, Anne-Mari and Kaminski, Tadeusz and Gäddnäs, Fiia and Kuusela, Tuija and Roiko, Jane and Karlsson, Sari and Reinikainen, Matti and Surakka, Tero and Jyrkönen, Helena and Eiserbeck, Tanja and Kallinen, Jaana and Laurila, Jouko and Sälkiö, Sinikka and Lund, Vesa and Tuominen, Päivi and Perkola, Pauliina and Tuominen, Riikka and Hietaranta, Marika and Johansson, Satu and Hovilehto, Seppo and Kirsi, Anne and Tiainen, Pekka and Myllärinen, Tuija and Leino, Pirjo and Toropainen, Anne and Kuitunen, Anne and Tenhunen, Jyrki and Leppänen, Ilona and Levoranta, Markus and Hoppu, Sanna and Sauranen, Jukka and Kukkurainen, Atte and Kortelainen, Samuli and Varila, Simo and Inkinen, Outi and Koivuviita, Niina and Kotamäki, Jutta and Laine, Anu and Koivisto, Simo-Pekka and Hautamäki, Raku and Skinnar, Maria and FINNAKI Study Grp and FINNAKI Study Group
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149956 - e0149956
Background Apoptosis is a key mechanism involved in ischemic acute kidney injury (AKI), but its role in septic AKI is controversial. Biomarkers indicative of... 
MORTALITY | SHOCK | MARKER | MULTIDISCIPLINARY SCIENCES | ACUTE-RENAL-FAILURE | MECHANISMS | SERUM | DYSFUNCTION | CELL-FREE DNA | SEVERE SEPSIS | Physiological aspects | Genetic aspects | Research | Diagnosis | Biological markers | Acute renal failure | Apoptosis | Plasma | Cytokeratin | Intensive care | Hemodialysis | Ischemia | Consent | Rodents | Bioindicators | Deoxyribonucleic acid--DNA | Urine | Creatinine | Medical research | Mortality | Heat shock proteins | Hsp70 protein | Patients | Medicine | Studies | Hospitals | Biomarkers | Sepsis | Plasma levels | Kidney diseases | Anesthesiology | Kidney transplantation | Heat shock | Index Medicus | Deoxyribonucleic acid | DNA
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4. Full Text Soluble CD73 in critically Ill septic patients - Data from the prospective FINNAKI study
by Vaara, Suvi T and Hollmén, Maija and Korhonen, Anna-Maija and Maksimow, Mikael and Ala-Kokko, Tero and Salmi, Marko and Jalkanen, Sirpa and Pettilä, Ville and Laru-Sompa, Raili and Pulkkinen, Anni and Saarelainen, Minna and Reilama, Mikko and Tolmunen, Sinikka and Rantalainen, Ulla and Miettinen, Marja and Suvela, Markku and Pesola, Katrine and Saastamoinen, Pekka and Kauppinen, Sirpa and Kaukonen, Kirsi-Maija and Nisula, Sara and Suojaranta-Ylinen, Raili and Mildh, Leena and Haapio, Mikko and Nurminen, Laura and Sutinen, Sari and Pettilä, Leena and Laitinen, Helinä and Syrjä, Heidi and Henttonen, Kirsi and Lappi, Elina and Boman, Hillevi and Varpula, Tero and Porkka, Päivi and Sivula, Mirka and Rahkonen, Mira and Tsurkka, Anne and Nieminen, Taina and Pirttinen, Niina and Alaspää, Ari and Salanto, Ville and Juntunen, Hanna and Sanisalo, Teija and Parviainen, Ilkka and Uusaro, Ari and Ruokonen, Esko and Bendel, Stepani and Rissanen, Niina and Lång, Maarit and Rahikainen, Sari and Rissanen, Saija and Ahonen, Merja and Halonen, Elina and Vaskelainen, Eija and Poukkanen, Meri and Lintula, Esa and Suominen, Sirpa and Heikkinen, Jorma and Lavander, Timo and Heinonen, Kirsi and Juopperi, Anne-Mari and Kaminski, Tadeusz and Gäddnäs, Fiia and Kuusela, Tuija and Roiko, Jane and Karlsson, Sari and Reinikainen, Matti and Surakka, Tero and Jyrkönen, Helena and Eiserbeck, Tanja and Kallinen, Jaana and Laurila, Jouko and Sälkiö, Sinikka and Lund, Vesa and Tuominen, Päivi and Perkola, Pauliina and Tuominen, Riikka and Hietaranta, Marika and Johansson, Satu and Hovilehto, Seppo and Kirsi, Anne and Tiainen, Pekka and Myllärinen, Tuija and Leino, Pirjo and Toropainen, Anne and Kuitunen, Anne and Tenhunen, Jyrki and Leppänen, Ilona and Levoranta, Markus and Hoppu, Sanna and Sauranen, Jukka and Kukkurainen, Atte and Kortelainen, Samuli and Varila, Simo and Inkinen, Outi and Koivuviita, Niina and Kotamäki, Jutta and Laine, Anu and Koivisto, Simo-Pekka and Hautamäki, Raku and ... and FINNAKI Study Grp and FINNAKI Study Group
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, pp. e0164420 - e0164420
Background CD73 dephosphorylates adenosine monophosphate to adenosine that is an anti-inflammatory molecule inhibiting immune activation and vascular leakage.... 
MORTALITY | ACUTE KIDNEY INJURY | ECTO-5'-NUCLEOTIDASE CD73 | ORGAN FAILURE | MULTIDISCIPLINARY SCIENCES | SEVERE SEPSIS | Infection | Medical research | Analysis | Medicine, Experimental | Septic shock | Adenylic acid | Health aspects | Adenosine | Intensive care | Immune response | Kidneys | Adenosine monophosphate | AMP | Laboratories | Mortality | Inflammation | Patients | Medicine | Studies | Immunology | Hospitals | Pain | Ischemia | Rodents | Sepsis | CD73 antigen | Anesthesiology | Index Medicus
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5. Full Text Common Inflammation-Related Candidate Gene Variants and Acute Kidney Injury in 2647 Critically Ill Finnish Patients
by Vilander, LM and Vaara, ST and Kaunisto, MA and Pettila, V and Laru-Sompa, R and Pulkkinen, A and Saarelainen, M and Reilama, M and Tolmunen, S and Rantalainen, U and Miettinen, M and Suvela, M and Pesola, K and Saastamoinen, P and Kauppinen, S and Kaukonen, KM and Korhonen, AM and Nisula, S and Vaara, S and Suojaranta-Ylinen, R and Mildh, L and Haapio, M and Nurminen, L and Sutinen, S and Pettila, L and Laitinen, H and Syrja, H and Henttonen, K and Lappi, E and Boman, H and Varpula, T and Porkka, P and Sivula, M and Rahkonen, M and Tsurkka, A and Nieminen, T and Prittinen, N and Alaspaa, A and Salanto, V and Juntunen, H and Sanisalo, T and Parviainen, I and Uusaro, A and Ruokonen, E and Bendel, S and Rissanen, N and Lang, M and Rahikainen, S and Rissanen, S and Ahonen, M and Halonen, E and Vaskelainen, E and Poukkanen, M and Lintula, E and Suominen, S and Heikkinen, J and Lavander, T and Heinonen, K and Juopperi, AM and Kaminski, T and Gaddnas, F and Kuusela, T and Roiko, J and Karlsson, S and Reinikainen, M and Surakka, T and Jyrkonen, H and Eiserbeck, T and Kallinen, J and Lund, V and Tuominen, P and Perkola, P and Tuominen, R and Hietaranta, M and Johansson, S and Hovilehto, S and Kirsi, A and Tiainen, P and Myllarinen, T and Leino, P and Toropainen, A and Kuitunen, A and Leppanen, I and Levoranta, M and Hoppu, S and Sauranen, J and Tenhunen, J and Kukkurainen, A and Kortelainen, S and Varila, S and Inkinen, O and Koivuviita, N and Kotamaki, J and Laine, A and Ala-Kokko, T and Laurila, J and Salkio, S and Koivisto, SP and Hautamaki, R and Skinnar, M and FINNAKI Study Grp and The FINNAKI Study Group
JOURNAL OF CLINICAL MEDICINE, ISSN 2077-0383, 03/2019, Volume 8, Issue 3, p. 342
Acute kidney injury (AKI) is a syndrome with high incidence among the critically ill. Because the clinical variables and currently used biomarkers have failed... 
MORTALITY | human genetics | RISK-FACTORS | genetic variation | PROMOTER POLYMORPHISM | NECROSIS-FACTOR-ALPHA | ADVERSE OUTCOMES | SEPSIS | INTERLEUKIN-10 | MEDICINE, GENERAL & INTERNAL | PLASMA-LEVELS | acute kidney injury | ENDOTHELIAL GROWTH-FACTOR | GENOME-WIDE ASSOCIATION
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6. Full Text ESICM LIVES 2016: part one
by L Bos and L Schouten and L van Vught and M Wiewel and D Ong and O Cremer and A Artigas and I Martin-Loeches and A Hoogendijk and T van der Poll and J Horn and N Juffermans and M Schultz and N de Prost and T Pham and G Carteaux and A Mekontso Dessap and C Brun-Buisson and E Fan and G Bellani and J Laffey and A Mercat and L Brochard and B Maitre and P A Howells and D R Thickett and C Knox and D P Park and F Gao and O Tucker and T Whitehouse and D F McAuley and G D Perkins and L Pisani and J P Roozeman and F D Simonis and A Giangregorio and L R Schouten and S M Van der Hoeven and A Serpa Neto and E Festic and A M Dondorp and S Grasso and L D Bos and M J Schultz and M Koster-Brouwer and D Verboom and B Scicluna and K van de Groep and J Frencken and M Bonten and J I Ko and K S Kim and G J Suh and W Y Kwon and K Kim and J H Shin and O T Ranzani and E Prina and R Menendez and A Ceccato and R Mendez and C Cilloniz and A Gabarrus and M Ferrer and A Torres and A Urbano and L A Zhang and D Swigon and F Pike and R S Parker and G Clermont and C Scheer and S O Kuhn and A Modler and M Vollmer and C Fuchs and K Hahnenkamp and S Rehberg and M Gründling and A Taggu and N Darang and N Öveges and I László and K Tánczos and M Németh and G Lebák and B Tudor and D Érces and J Kaszaki and W Huber and D Trásy and Z Molnár and G Ferrara and V S Kanoore Edul and H S Canales and E Martins and C Canullán and G Murias and M O Pozo and ...
Intensive Care Medicine Experimental, 09/2016, Volume 4, Issue 1, pp. 1 - 203
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7. Full Text ESICM LIVES 2016: part two : Milan, Italy. 1-5 October 2016
by Sivakumar, S and Taccone, F.S and Desai, K.S and Rood, P.J.T and Schoor, F. van de and Tertholen, K. van and Pickkers, P and Boogaard, M.H.W.A. van den and TAVeM study group and The FINNAKI Study Group and POPC-CB investigators and DESIRE (DExmedetomidine for Sepsis in ICU Randomized Evaluation) Trial Investigators and PLUG Working group and SIRAKI group and on behalf of Department of Professional Development, ESICM and Nurses of the Central and General ICUs of Shiraz Namazi Hospital and Renal Transplantation HUVR and Grupo ESBAGA and GEMINI and SPACeR group (Surrey Peri-operative, Anaesthesia and Critical Care Collaborative Research Group) and Sedation an Delirium Group Hospital Universitari de Bellvitge and Queen Square Neuroanaesthesia and Neurocritical Care Resreach Group and for the PRoVENT investigators and the PROVE Network and SEMICYUC/GETGAG Working Group and Critical Care Research Group and EDISVAL Group and Bioethics work group of SEMICYUC
Intensive Care Medicine Experimental, ISSN 2197-425X, 2016, Volume 4, Issue S1, pp. 30 - 30
Medicine & Public Health | Intensive / Critical Care Medicine
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