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humans (14) 14
aged (13) 13
female (13) 13
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medicine, general & internal (10) 10
postmenopause (9) 9
risk (9) 9
follow-up studies (8) 8
double-blind method (7) 7
estrogens, conjugated - therapeutic use (7) 7
hormone replacement therapy (7) 7
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risk factors (7) 7
women (7) 7
prevention (6) 6
clinical trials (5) 5
estrogen (5) 5
estrogen replacement therapy (5) 5
hormone therapy (5) 5
incidence (5) 5
menopause (5) 5
calcium carbonate - adverse effects (4) 4
health aspects (4) 4
peripheral vascular disease (4) 4
vitamin d - therapeutic use (4) 4
alfacalcidol (3) 3
calcifediol (3) 3
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calcium carbonate - therapeutic use (3) 3
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cardiac & cardiovascular systems (3) 3
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colorectal neoplasms - epidemiology (3) 3
drug combinations (3) 3
estrogen replacement therapy - adverse effects (3) 3
estrogens, conjugated - adverse effects (3) 3
fractures (3) 3
fractures, bone - epidemiology (3) 3
health risk assessment (3) 3
medroxyprogesterone acetate - adverse effects (3) 3
metaanalysis (3) 3
myocardial infarction - epidemiology (3) 3
progesterone congeners - therapeutic use (3) 3
research (3) 3
vitamin d (3) 3
vitamin d - adverse effects (3) 3
vitamin d - pharmacology (3) 3
womens health (3) 3
adverse and side effects (2) 2
age factors (2) 2
base-line characteristics (2) 2
bone density - drug effects (2) 2
calcium (2) 2
calcium carbonate - pharmacology (2) 2
cardiovascular diseases (2) 2
cardiovascular-disease (2) 2
case-control studies (2) 2
colon-cancer (2) 2
colorectal cancer (2) 2
colorectal neoplasms (2) 2
colorectal neoplasms - pathology (2) 2
colorectal neoplasms - prevention & control (2) 2
coronary disease - prevention & control (2) 2
coronary-heart-disease (2) 2
dietary calcium (2) 2
dietary supplements (2) 2
endometrial neoplasms - epidemiology (2) 2
estrogen/progestin replacement (2) 2
evaluation (2) 2
fractures, bone - prevention & control (2) 2
gynecology (2) 2
hematology (2) 2
hip fractures - prevention & control (2) 2
hypertension (2) 2
hypertension - epidemiology (2) 2
kidney calculi - chemically induced (2) 2
medroxyprogesterone 17 acetate (2) 2
osteoporosis (2) 2
osteoporotic fractures (2) 2
participants (2) 2
patient compliance (2) 2
progesterone (2) 2
progesterone congeners - adverse effects (2) 2
progression (2) 2
randomized controlled-trial (2) 2
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stroke - epidemiology (2) 2
treatment outcome (2) 2
vitamin d - administration & dosage (2) 2
vitamin d - blood (2) 2
25-dihydroxyvitamin d (1) 1
25-dihydroxyvitaniin d (1) 1
25-hydroxyvitamin d (1) 1
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1. Full Text Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial
by Writing Group for the Women's Health Initiative Investigators and Writing Group for the Women's Health Initiative Investigators
JAMA, ISSN 0098-7484, 07/2002, Volume 288, Issue 3, pp. 321 - 333
CONTEXT Despite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains... 
MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | METAANALYSIS | EVENTS | BREAST-CANCER RISK | CORONARY-ARTERY ATHEROSCLEROSIS | CARDIOVASCULAR-DISEASE | FRACTURES | HORMONE REPLACEMENT THERAPY | ASSOCIATION | SECONDARY PREVENTION | Myocardial Infarction - epidemiology | Humans | Middle Aged | Fractures, Bone - epidemiology | Coronary Disease - epidemiology | Risk | Pulmonary Embolism - epidemiology | Medroxyprogesterone Acetate - adverse effects | Postmenopause | Female | Stroke - epidemiology | Breast Neoplasms - epidemiology | Colorectal Neoplasms - epidemiology | Progesterone Congeners - adverse effects | Progesterone Congeners - therapeutic use | Medroxyprogesterone Acetate - therapeutic use | Proportional Hazards Models | Thrombosis - epidemiology | Treatment Outcome | Endometrial Neoplasms - epidemiology | Estrogen Replacement Therapy - adverse effects | Breast Neoplasms - prevention & control | Estrogens, Conjugated (USP) - therapeutic use | Coronary Disease - prevention & control | Clinical Trials Data Monitoring Committees | Survival Analysis | Aged | Estrogens, Conjugated (USP) - adverse effects | Fractures, Bone - prevention & control | Hormone therapy | Evaluation | Women | Health risk assessment | Hormone replacement therapy
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2. Full Text Effects of Estrogen Plus Progestin on Risk of Fracture and Bone Mineral Density: The Women's Health Initiative Randomized Trial
by Cauley, Jane A and Robbins, John and Chen, Zhao and Cummings, Steven R and Jackson, Rebecca D and LaCroix, Andrea Z and LeBoff, Meryl and Lewis, Cora E and McGowan, Joan and Neuner, Joan and Pettinger, Mary and Stefanick, Marcia L and Wactawski-Wende, Jean and Watts, Nelson B and for the Women's Health Initiative Investigators and Women's Hlth Initiative Investigat and Women's Health Initiative Investigators
JAMA, ISSN 0098-7484, 10/2003, Volume 290, Issue 13, pp. 1729 - 1738
CONTEXT In the Women's Health Initiative trial of estrogen-plus-progestin therapy, women assigned to active treatment had fewer fractures. OBJECTIVE To test... 
HIP FRACTURE | MEDICINE, GENERAL & INTERNAL | VERTEBRAL FRACTURES | NONVERTEBRAL FRACTURES | ELDERLY WOMEN | OSTEOPOROTIC FRACTURES | PREVENTION | OLDER WOMEN | HORMONE REPLACEMENT THERAPY | POSTMENOPAUSAL WOMEN | ESTROGEN/PROGESTIN REPLACEMENT | Estrogen Replacement Therapy | Double-Blind Method | Progesterone Congeners - therapeutic use | Humans | Middle Aged | Medroxyprogesterone Acetate - therapeutic use | Proportional Hazards Models | Fractures, Bone - epidemiology | Risk | Estrogens, Conjugated (USP) - therapeutic use | Bone Density - drug effects | Postmenopause | Female | Aged | Osteoporosis - epidemiology | Prevention | Postmenopausal women | Fractures | Hormone therapy | Health aspects | Osteoporosis | Menopause | Gynecology | Estrogen | Hormone replacement therapy | Health risk assessment
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3. Full Text Effects of Estrogen Plus Progestin on Gynecologic Cancers and Associated Diagnostic Procedures: The Women's Health Initiative Randomized Trial
by Anderson, Garnet L and Judd, Howard L and Kaunitz, Andrew M and Barad, David H and Beresford, Shirley A. A and Pettinger, Mary and Liu, James and McNeeley, S. Gene and Lopez, Ana Maria and for the Women's Health Initiative Investigators and Women's Hlth Initiative Investigat and Women's Health Initiative Investigators
JAMA, ISSN 0098-7484, 10/2003, Volume 290, Issue 13, pp. 1739 - 1748
CONTEXT The effects of continuous combined hormone therapy on gynecologic cancers have not been investigated previously in a randomized trial setting.... 
MEDICINE, GENERAL & INTERNAL | PREVENTION | RISK | PIPELLE | HORMONE REPLACEMENT THERAPY | POSTMENOPAUSAL WOMEN | EPITHELIAL OVARIAN-CANCER | ENDOMETRIAL CANCER | Estrogen Replacement Therapy | Uterine Cervical Neoplasms - diagnosis | Double-Blind Method | Ovarian Neoplasms - diagnosis | Humans | Middle Aged | Uterine Cervical Neoplasms - epidemiology | Medroxyprogesterone Acetate - therapeutic use | Proportional Hazards Models | Vaginal Smears | Endometrial Neoplasms - epidemiology | Endometrial Neoplasms - diagnosis | Genital Neoplasms, Female - epidemiology | Ovarian Neoplasms - epidemiology | Genital Neoplasms, Female - diagnosis | Estrogens, Conjugated (USP) - therapeutic use | Biopsy | Postmenopause | Female | Aged | Endometrium - pathology | Adverse and side effects | Hormone therapy | Risk factors | Ovarian cancer | Menopause | Gynecology | Estrogen | Hormone replacement therapy | Health risk assessment | Cervical cancer
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4. Full Text Estrogen Plus Progestin and Risk of Venous Thrombosis
by Cushman, Mary and Kuller, Lewis H and Prentice, Ross and Rodabough, Rebecca J and Psaty, Bruce M and Stafford, Randall S and Sidney, Steven and Rosendaal, Frits R and Women’s Health Initiative Investigators, for the and Women's Hlth Initiative Investigat and Women's Health Initiative Investigators
JAMA, ISSN 0098-7484, 10/2004, Volume 292, Issue 13, pp. 1573 - 1580
CONTEXT Postmenopausal hormone therapy increases the risk of venous thrombosis. It is not known whether other factors influencing thrombosis add to this risk.... 
HEART | MEDICINE, GENERAL & INTERNAL | FACTOR-V-LEIDEN | DISEASE | THROMBOEMBOLISM | OUTCOMES | HORMONE REPLACEMENT THERAPY | HEALTHY POSTMENOPAUSAL WOMEN | USERS | CANCER | BREAST | Body Mass Index | Obesity | Age Factors | Double-Blind Method | Follow-Up Studies | Humans | Middle Aged | Blood Coagulation Factors | Medroxyprogesterone Acetate - therapeutic use | Proportional Hazards Models | Risk | Case-Control Studies | Estrogen Replacement Therapy - adverse effects | Venous Thrombosis - etiology | Incidence | Factor V | Estrogens, Conjugated (USP) - therapeutic use | Venous Thrombosis - epidemiology | Medroxyprogesterone Acetate - adverse effects | Postmenopause | Female | Aged | Estrogens, Conjugated (USP) - adverse effects | Women | Estrogen | Thrombophlebitis | Research | Progesterone | Health aspects | Risk factors | Medical research | Clinical trials | Hormone replacement therapy | Blood clots
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5. Full Text No Increase in Fractures after Stopping Hormone Therapy: Results from the Women’s Health Initiative
by Watts, Nelson B and Cauley, Jane A and Jackson, Rebecca D and LaCroix, Andrea Z and Lewis, Cora E and Manson, JoAnn E and Neuner, Joan and Phillips, Lawrence S and Stefanick, Marcia L and Wactawski-Wende, Jean and Crandall, Carolyn and for the Women’s Health Initiative Investigators
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 11/2016, p. jc.2016-3270
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6. Full Text Calcium/vitamin D supplementation and cardiovascular events
by Hsia, Judith and Heiss, Gerardo and Ren, Hong and Allison, Matthew and Dolan, Nancy C and Greenland, Philip and Heckbert, Susan R and Johnson, Karen C and Manson, Joann E and Sidney, Stephen and Trevisan, Maurizio and Womens Hlth Initiative and Women's Health Initiative Investigators
Circulation, ISSN 0009-7322, 02/2007, Volume 115, Issue 7, pp. 846 - 854
Background - Individuals with vascular or valvular calcification are at increased risk for coronary events, but the relationship between calcium consumption... 
Women | Cerebrovascular disorders | Stroke | Calcium | Coronary disease | MORTALITY | VITAMIN-D SUPPLEMENTATION | CARDIAC & CARDIOVASCULAR SYSTEMS | calcium | MYOCARDIAL-INFARCTION | VASCULAR CALCIFICATION | stroke | coronary disease | BONE-FORMATION | CALCIUM INTAKE | PERIPHERAL VASCULAR DISEASE | HEALTH | cerebrovascular disorders | CORONARY-HEART-DISEASE | ESTROGEN PLUS PROGESTIN | POSTMENOPAUSAL WOMEN | HEMATOLOGY | women | Cardiovascular Diseases - etiology | France - epidemiology | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Calcium Carbonate - therapeutic use | Calcium Carbonate - adverse effects | Cerebrovascular Disorders - etiology | Vitamin D - adverse effects | Cerebrovascular Disorders - prevention & control | Cardiovascular Diseases - epidemiology | Postmenopause | Female | Aged | Cerebrovascular Disorders - epidemiology | Vitamin D - therapeutic use | Dietary Supplements | Complications and side effects | Calcium, Dietary | Vitamin D | Dietary supplements | Calcifediol | Research | Alfacalcidol | Cardiovascular diseases | Risk factors | Cerebrovascular disease
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7. Full Text Prehypertension and cardiovascular disease risk in the women's health initiative
by Hsia, Judith and Margolis, Karen L and Eaton, Charles B and Wenger, Nanette K and Allison, Matthew and Wu, Lieling and LaCroix, Andrea Z and Black, Henry R and Womens Hlth Initiative and Women's Health Initiative Investigators
Circulation, ISSN 0009-7322, 02/2007, Volume 115, Issue 7, pp. 855 - 860
Background - Prehypertension is common and is associated with increased vascular mortality. The extent to which it increases risk of nonfatal myocardial... 
Hypertension | Myocardial infarction | Women | Stroke | Risk factors | UNITED-STATES | risk factors | NORMAL BLOOD-PRESSURE | CARDIAC & CARDIOVASCULAR SYSTEMS | CLINICAL-TRIAL | myocardial infarction | PREVALENCE | JOINT NATIONAL COMMITTEE | stroke | BASE-LINE CHARACTERISTICS | DIET | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | hypertension | INTERVENTION | PARTICIPANTS | women | United States - epidemiology | Myocardial Infarction - epidemiology | Prevalence | Women's Health | Follow-Up Studies | Humans | Middle Aged | Risk | Stroke - etiology | Hypertension - complications | Female | Stroke - epidemiology | Aged | Hypertension - epidemiology | Heart Failure - epidemiology | Heart Failure - etiology | Myocardial Infarction - etiology | Demographic aspects | Reports | Research | Cardiovascular diseases | Health aspects
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8. Full Text Effect of Calcium and Vitamin D Supplementation on Blood Pressure: The Womenʼs Health Initiative Randomized Trial
by Margolis, Karen L and Ray, Roberta M and Van Horn, Linda and Manson, JoAnn E and Allison, Matthew A and Black, Henry R and Beresford, Shirley A.A and Connelly, Stephanie A and Curb, J David and Grimm, Richard H and Kotchen, Theodore A and Kuller, Lewis H and Wassertheil-Smoller, Sylvia and Thomson, Cynthia A and Torner, James C and Womens Hlth Initiative Investigat and Women's Health Initiative Investigators
Hypertension, ISSN 0194-911X, 11/2008, Volume 52, Issue 5, pp. 847 - 855
Experimental and epidemiological studies suggest that calcium and vitamin D supplements may lower blood pressure. We examined the effect of calcium plus... 
Hypertension | Clinical trials | Blood pressure | 25-Dihydroxyvitaniin D | Calcium supplementation | 25-Hydroxyvitamin D | blood pressure | calcium supplementation | METAANALYSIS | 25-hydroxyvitamin D | DIETARY CALCIUM | 25-dihydroxyvitamin D | RISK | PATTERNS | PERIPHERAL VASCULAR DISEASE | clinical trials | hypertension | Calcium - pharmacology | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Calcium - administration & dosage | Vitamin D - pharmacology | Hypertension - physiopathology | Incidence | Dose-Response Relationship, Drug | Calcium - therapeutic use | Hypertension - prevention & control | Female | Vitamin D - administration & dosage | Aged | Blood Pressure - drug effects | Blood Pressure - physiology | Hypertension - epidemiology | Patient Compliance | Vitamin D - therapeutic use | Dietary Supplements | Longitudinal Studies
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9. Full Text Calcium plus Vitamin D Supplementation and the Risk of Fractures
by Jackson, Rebecca D and LaCroix, Andrea Z and Gass, Margery and Wallace, Robert B and Robbins, John and Lewis, Cora E and Bassford, Tamsen and Beresford, Shirley A.A and Black, Henry R and Blanchette, Patricia and Bonds, Denise E and Brunner, Robert L and Brzyski, Robert G and Caan, Bette and Cauley, Jane A and Chlebowski, Rowan T and Cummings, Steven R and Granek, Iris and Hays, Jennifer and Heiss, Gerardo and Hendrix, Susan L and Howard, Barbara V and Hsia, Judith and Hubbell, F. Allan and Johnson, Karen C and Judd, Howard and Kotchen, Jane Morley and Kuller, Lewis H and Langer, Robert D and Lasser, Norman L and Limacher, Marian C and Ludlam, Shari and Manson, JoAnn E and Margolis, Karen L and McGowan, Joan and Ockene, Judith K and O'Sullivan, Mary Jo and Phillips, Lawrence and Prentice, Ross L and Sarto, Gloria E and Stefanick, Marcia L and Van Horn, Linda and Wactawski-Wende, Jean and Whitlock, Evelyn and Anderson, Garnet L and Assaf, Annlouise R and Barad, David and Womens Hlth Initiative Investigat and Women's Health Initiative Investigators
The New England Journal of Medicine, ISSN 0028-4793, 02/2006, Volume 354, Issue 7, pp. 669 - 683
The efficacy of calcium with vitamin D supplementation in preventing hip and other fractures in healthy postmenopausal women remains equivocal. In this Women's... 
MEDICINE, GENERAL & INTERNAL | MINERAL DENSITY | METAANALYSIS | CLINICAL-TRIAL | POSTMENOPAUSAL BONE LOSS | OSTEOPOROTIC FRACTURES | PREVENTION | ESTROGEN | ELDERLY-WOMEN | HIP-FRACTURES | RANDOMIZED CONTROLLED-TRIAL | Estrogen Replacement Therapy | Follow-Up Studies | Humans | Middle Aged | Fractures, Bone - epidemiology | Risk | Spinal Fractures - prevention & control | Drug Interactions | Hip Fractures - prevention & control | Postmenopause | Female | Kidney Calculi - chemically induced | Double-Blind Method | Proportional Hazards Models | Calcium Carbonate - therapeutic use | Vitamin D - pharmacology | Calcium Carbonate - adverse effects | Vitamin D - blood | Vitamin D - adverse effects | Bone Density - drug effects | Calcium - therapeutic use | Aged | Patient Compliance | Vitamin D - therapeutic use | Calcium Carbonate - pharmacology | Drug Combinations | Fractures, Bone - prevention & control | Hip joint | Usage | Care and treatment | Calcium, Dietary | Fractures | Vitamin D | Calcifediol | Alfacalcidol | Clinical trials | Preventive medicine | Calcium | Menopause
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10. Full Text Calcium plus Vitamin D Supplementation and the Risk of Colorectal Cancer
by Wactawski-Wende, Jean and Kotchen, Jane Morley and Anderson, Garnet L and Assaf, Annlouise R and Brunner, Robert L and O'Sullivan, Mary Jo and Margolis, Karen L and Ockene, Judith K and Phillips, Lawrence and Pottern, Linda and Prentice, Ross L and Robbins, John and Rohan, Thomas E and Sarto, Gloria E and Sharma, Santosh and Stefanick, Marcia L and Van Horn, Linda and Wallace, Robert B and Whitlock, Evelyn and Bassford, Tamsen and Beresford, Shirley A.A and Black, Henry R and Bonds, Denise E and Brzyski, Robert G and Caan, Bette and Chlebowski, Rowan T and Cochrane, Barbara and Garland, Cedric and Gass, Margery and Hays, Jennifer and Heiss, Gerardo and Hendrix, Susan L and Howard, Barbara V and Hsia, Judith and Hubbell, F. Allan and Jackson, Rebecca D and Johnson, Karen C and Judd, Howard and Kooperberg, Charles L and Kuller, Lewis H and LaCroix, Andrea Z and Lane, Dorothy S and Langer, Robert D and Lasser, Norman L and Lewis, Cora E and Limacher, Marian C and Manson, JoAnn E and Womens Hlth Initative Investigat and Women's Health Initiative Investigators
The New England Journal of Medicine, ISSN 0028-4793, 02/2006, Volume 354, Issue 7, pp. 684 - 696
Supplemental calcium and vitamin D have been associated with a reduced risk of colorectal cancer in epidemiologic and polyp-prevention studies, but evidence... 
COLON-CANCER | TRIAL | WOMEN | MEDICINE, GENERAL & INTERNAL | DIETARY CALCIUM | DAIRY-PRODUCTS | PREVENTION | ADENOMA | PARTICIPANTS | BASE-LINE CHARACTERISTICS | PROSPECTIVE COHORT | Colorectal Neoplasms - epidemiology | Double-Blind Method | Follow-Up Studies | Humans | Middle Aged | Proportional Hazards Models | Calcium Carbonate - therapeutic use | Colorectal Neoplasms - prevention & control | Vitamin D - pharmacology | Colonic Polyps - epidemiology | Calcium Carbonate - adverse effects | Incidence | Vitamin D - blood | Vitamin D - adverse effects | Adenocarcinoma - prevention & control | Calcium - therapeutic use | Postmenopause | Female | Aged | Vitamin D - therapeutic use | Adenocarcinoma - epidemiology | Colorectal Neoplasms - pathology | Calcium Carbonate - pharmacology | Drug Combinations | Prevention | Calcium, Dietary | Vitamin D | Colorectal cancer | Calcifediol | Dosage and administration | Alfacalcidol | Womens health | Consent | Older people | Endocrine therapy | Bone density
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11. Full Text Effects of Estrogen plus Progestin on Health-Related Quality of Life
by Hays, Jennifer and Ockene, Judith K and Brunner, Robert L and Kotchen, Jane M and Manson, JoAnn E and Patterson, Ruth E and Aragaki, Aaron K and Shumaker, Sally A and Brzyski, Robert G and LaCroix, Andrea Z and Granek, Iris A and Valanis, Barbara G and Women's Hlth Initiative Investigat and Women's Health Initiative Investigators
The New England Journal of Medicine, ISSN 0028-4793, 05/2003, Volume 348, Issue 19, pp. 1839 - 1854
The Women's Health Initiative previously established that therapy with estrogen and progestin does not prevent disease in postmenopausal women. In the same... 
MEDICINE, GENERAL & INTERNAL | SYMPTOMS | SURVEY SF-36 | DIFFERENCE | HORMONE REPLACEMENT THERAPY | POSTMENOPAUSAL WOMEN | Estrogen Replacement Therapy | Hot Flashes - drug therapy | Estrogens - pharmacology | Progestins - therapeutic use | Sleep Wake Disorders - drug therapy | Humans | Middle Aged | Progestins - pharmacology | Linear Models | Mental Health | Cognition - drug effects | Estrogens - therapeutic use | Depression - drug therapy | Quality of Life | Female | Aged | Sexual Behavior - drug effects | Health Status | Hormone therapy | Evaluation | Quality of life | Hormone replacement therapy
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