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breast cancer (15) 15
science & technology (14) 14
life sciences & biomedicine (13) 13
mutation (13) 13
humans (12) 12
female (11) 11
genetic predisposition to disease (10) 10
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by Maxwell, Christopher A and Benítez, Javier and Gómez-Baldó, Laia and Osorio, Ana and Bonifaci, Núria and Fernández-Ramires, Ricardo and Costes, Sylvain V and Guinó, Elisabet and Chen, Helen and Evans, Gareth J. R and Mohan, Pooja and Català, Isabel and Petit, Anna and Aguilar, Helena and Villanueva, Alberto and Aytes, Alvaro and Serra-Musach, Jordi and Rennert, Gad and Lejbkowicz, Flavio and Peterlongo, Paolo and Manoukian, Siranoush and Peissel, Bernard and Ripamonti, Carla B and Bonanni, Bernardo and Viel, Alessandra and Allavena, Anna and Bernard, Loris and Radice, Paolo and Friedman, Eitan and Kaufman, Bella and Laitman, Yael and Dubrovsky, Maya and Milgrom, Roni and Jakubowska, Anna and Cybulski, Cezary and Gorski, Bohdan and Jaworska, Katarzyna and Durda, Katarzyna and Sukiennicki, Grzegorz and Lubiński, Jan and Shugart, Yin Yao and Domchek, Susan M and Letrero, Richard and Weber, Barbara L and Hogervorst, Frans B. L and Rookus, Matti A and Collee, J. Margriet and Devilee, Peter and Ligtenberg, Marjolijn J and van der Luijt, Rob B and Aalfs, Cora M and Waisfisz, Quinten and Wijnen, Juul and van Roozendaal, Cornelis E. P and Easton, Douglas F and Peock, Susan and Cook, Margaret and Oliver, Clare and Frost, Debra and Harrington, Patricia and Evans, D. Gareth and Lalloo, Fiona and Eeles, Rosalind and Izatt, Louise and Chu, Carol and Eccles, Diana and Douglas, Fiona and Brewer, Carole and Nevanlinna, Heli and Heikkinen, Tuomas and Couch, Fergus J and Lindor, Noralane M and Wang, Xianshu and Godwin, Andrew K and Caligo, Maria A and Lombardi, Grazia and Loman, Niklas and Karlsson, Per and Ehrencrona, Hans and von Wachenfeldt, Anna and Bjork Barkardottir, Rosa and Hamann, Ute and Rashid, Muhammad U and Lasa, Adriana and Caldés, Trinidad and Andrés, Raquel and Schmitt, Michael and Assmann, Volker and Stevens, Kristen and Offit, Kenneth and Curado, João and Tilgner, Hagen and Guigó, Roderic and Aiza, Gemma and Brunet, Joan and Castellsagué, Joan and Martrat, Griselda and Urruticoechea, Ander and Blanco, Ignacio and Tihomirova, Laima and ... and HEBON and EMBRACE and GEMO Study Collaborators and kConFab and BCFR and SWE-BRCA and Institute of Clinical Sciences, Department of Oncology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för kliniska vetenskaper, Avdelningen för onkologi
PLoS biology, ISSN 1545-7885, 11/2011, Volume 9, Issue 11, pp. e1001199 - e1001199
Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation... 
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Epithelial Cells - metabolism | Humans | Receptors, Estrogen - analysis | Breast Neoplasms - metabolism | Aurora Kinase A | Genetic Variation | BRCA1 Protein - metabolism | Hyaluronan Receptors - metabolism | Microtubules - ultrastructure | Genes, BRCA2 | Female | Genes, BRCA1 | Epithelial Cells - cytology | Extracellular Matrix Proteins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Genetic Predisposition to Disease | Breast - cytology | Extracellular Matrix Proteins - genetics | Microtubules - physiology | Genotype | Aurora Kinases | Hyaluronan Receptors - genetics | BRCA1 Protein - genetics | Cell Polarity - genetics | BRCA2 Protein - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Heterozygote | HeLa Cells | BRCA2 Protein - genetics | BRCA mutations | Physiological aspects | Breast cancer | Genetic aspects | Polarity (Biology) | Research | Health aspects | Risk factors | Cancer | Confidence intervals | Medical research | Hospitals | Biomedical research | Colleges & universities | Mutation | Index Medicus | Càncer de mama | Oncogens | Cèl·lules epitelials | Epithelial cells | Oncogenes | Antigens, CD44 | Cell Polarity | Receptors, Estrogen | Protein-Serine-Threonine Kinases | Epithelial Cells | Breast Neoplasms | Life Sciences | Extracellular Matrix Proteins | Microtubules | BRCA2 Protein | Breast | BRCA1 Protein | Immunologi inom det medicinska området | Cancer and Oncology | Immunology in the medical area | Cancer och onkologi
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 1460-2105, 07/2017, Volume 109, Issue 7, p. djw302
Journal Article
PLoS genetics, ISSN 1553-7404, 2010, Volume 6, Issue 10, pp. e1001183 - e1001183
Journal Article
Human mutation, ISSN 1059-7794, 07/2019, Volume 40, Issue 10, pp. 1781 - 1796
Journal Article
by Couch, Fergus J and Wang, Xianshu and McGuffog, Lesley and Lee, Andrew and Olswold, Curtis and Kuchenbaecker, Karoline B and Soucy, Penny and Fredericksen, Zachary and Barrowdale, Daniel and Dennis, Joe and Gaudet, Mia M and Dicks, Ed and Kosel, Matthew and Healey, Sue and Sinilnikova, Olga M and Lee, Adam and Bacot, François and Vincent, Daniel and Hogervorst, Frans B. L and Peock, Susan and Stoppa-Lyonnet, Dominique and Jakubowska, Anna and Investigators, kConFab and Radice, Paolo and Schmutzler, Rita Katharina and Domchek, Susan M and Piedmonte, Marion and Singer, Christian F and Friedman, Eitan and Thomassen, Mads and Hansen, Thomas V. O and Neuhausen, Susan L and Szabo, Csilla I and Blanco, Ignacio and Greene, Mark H and Karlan, Beth Y and Garber, Judy and Phelan, Catherine M and Weitzel, Jeffrey N and Montagna, Marco and Olah, Edith and Andrulis, Irene L and Godwin, Andrew K and Yannoukakos, Drakoulis and Goldgar, David E and Caldes, Trinidad and Nevanlinna, Heli and Osorio, Ana and Terry, Mary Beth and Daly, Mary B and van Rensburg, Elizabeth J and Hamann, Ute and Ramus, Susan J and Ewart Toland, Amanda and Caligo, Maria A and Olopade, Olufunmilayo I and Tung, Nadine and Claes, Kathleen and Beattie, Mary S and Southey, Melissa C and Imyanitov, Evgeny N and Tischkowitz, Marc and Janavicius, Ramunas and John, Esther M and Kwong, Ava and Diez, Orland and Balmaña, Judith and Barkardottir, Rosa B and Arun, Banu K and Rennert, Gad and Teo, Soo-Hwang and Ganz, Patricia A and Campbell, Ian and van der Hout, Annemarie H and van Deurzen, Carolien H. M and Seynaeve, Caroline and Gómez Garcia, Encarna B and van Leeuwen, Flora E and Meijers-Heijboer, Hanne E. J and Gille, Johannes J. P and Ausems, Margreet G. E. M and Blok, Marinus J and Ligtenberg, Marjolijn J. L and Rookus, Matti A and Devilee, Peter and Verhoef, Senno and van Os, Theo A. M and Wijnen, Juul T and Frost, Debra and Ellis, Steve and Fineberg, Elena and Platte, Radka and Evans, D. Gareth and Izatt, Louise and Eeles, Rosalind A and Adlard, Julian and Eccles, Diana M and Cook, Jackie and Brewer, Carole and Douglas, Fiona and ... and Ontario Cancer Genetics Network and EMBRACE and GEMO Study Collaborators and HEBON and on behalf of CIMBA and BCFR and SWE-BRCA and KConFab Investigators and Ontario Canc Genetics Network and CIMBA
PLoS genetics, ISSN 1553-7404, 03/2013, Volume 9, Issue 3, pp. e1003212 - e1003212
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 0027-8874, 04/2019, Volume 111, Issue 4, p. 350
Background: BRCA1/2 mutations confer high lifetime risk of breast cancer, although other factors may modify this risk. Whether height or body mass index (BMI)... 
Oncology | Cancer Research | Journal Article
Journal Article
by Blein, Sophie and Bardel, Claire and Danjean, Vincent and McGuffog, Lesley and Healey, Sue and Barrowdale, Daniel and Lee, Andrew and Dennis, Joe and Kuchenbaecker, Karoline B and Soucy, Penny and Terry, Mary Beth and Chung, Wendy K and Goldgar, David E and Janavicius, Ramunas and Buys, Saundra S and Tihomirova, Laima and Tung, Nadine and Dorfling, Cecilia M and Neuhausen, Susan L and Van Rensburg, Elizabeth J and Ding, Yuan Chun and Gerdes, Anne-Marie and Ejlertsen, Bent and Nielsen, Finn C and Hansen, Thomas V. O and Osorio, Ana and Benitez, Javier and Conejero, Raquel Andrés and Segota, Ena and Weitzel, Jeffrey N and Thelander, Margo and Peterlongo, Paolo and Radice, Paolo and Pensotti, Valeria and Dolcetti, Riccardo and Peissel, Bernard and Bonanni, Bernardo and Zaffaroni, Daniela and Scuvera, Giulietta and Manoukian, Siranoush and Capone, Gabriele L and Varesco, Liliana and Papi, Laura and Ottini, Laura and Yannoukakos, Drakoulis and Konstantopoulou, Irene and Garber, Judy and Donaldson, Alan and Hamann, Ute and Brady, Angela and Brewer, Carole and Foo, Claire and Evans, D Gareth and Frost, Debra and Eccles, Diana and Douglas, Fiona and Cook, Jackie and Adlard, Julian and Barwell, Julian and Walker, Lisa and Izatt, Louise and Kennedy, M. John and Rogers, Mark T and Side, Lucy E and Tischkowitz, Marc and Porteous, Mary E and Morrison, Patrick J and Platte, Radka and Davidson, Rosemarie and Eeles, Ros and Hodgson, Shirley and Cole, Trevor and Godwin, Andrew K and Isaacs, Claudine and Claes, Kathleen and Leeneer, Kim De and Meindl, Alfons and Gehrig, Andrea and Wappenschmidt, Barbara and Engel, Christoph and Sutter, Christian and Niederacher, Dieter and Steinemann, Doris and Plendl, Hansjoerg and Kast, Karin and Rhiem, Kerstin and Ditsch, Nina and Arnold, Norbert and Varon-Mateeva, Raymonda and Schmutzler, Rita K and Preisler-Adams, Sabine and Markov, Nadja Bogdanova and Wang-Gohrke, Shan and De Pauw, Antoine and Lefol, Cédrick and Leroux, Dominique and Lasset, Christine and Rouleau, Etienne and Damiola, Francesca and Dreyfus, Hélène and ...
Breast cancer research : BCR, ISSN 1465-5411, 06/2017
Introduction: Individuals carrying pathogenic mutations in the BRCA1 and BRCA2 genes have a high lifetime risk of breast cancer. BRCA1 and BRCA2 are involved... 
Oncology | Mitochondrial DNA | Breast--Cancer--Genetic aspects | Mutation (Biology)
Journal Article
by Lesueur, Fabienne and Mebirouk, Noura and Jiao, Yue and Barjhoux, Laure and Belotti, Muriel and Laurent, Maïté and Léone, Mélanie and Houdayer, Claude and Paillerets, Brigitte Bressacde and Vaur, Dominique and Sobol, Hagay and Noguès, Catherine and Longy, Michel and Mortemousque, Isabelle and Fert-Ferrer, Sandra and Mouret-Fourme, Emmanuelle and Pujol, Pascal and Venat-Bouvet, Laurence and Bignon, Yves-Jean and Leroux, Dominique and Coupier, Isabelle and Berthet, Pascaline and Mari, Véronique and Delnatte, Capucine and Gesta, Paul and Collonge-Rame, Marie-Agnès and Giraud, Sophie and Bonadona, Valérie and Baurand, Amandine and Faivre, Laurence and Buecher, Bruno and Lasset, Christine and Gauthier-Villars, Marion and Damiola, Francesca and Mazoyer, Sylvie and Caputo, Sandrine M and Andrieu, Nadine and Stoppa-Lyonnet, Dominique and Lesueur, Fabienne and Mebirouk, Noura and Jiao, Y and Barjhoux, Laure and Belotti, Muriel and Laurent, M and Léone, M and Houdayer, C and Bressac-De Paillerets, B and Vaur, D and Sobol, H and Nogués, C and Longy, M and Mortemousque, I and Fert-Ferrer, S and Mouret-Fourme, E and Pujol, P and Venat-Bouvet, L and Bignon, Y.-J and Leroux, D and Coupier, I and Berthet, P and Mari, V and Delnatte, C and Gesta, P and Collonge-Rame, M.-A and Giraud, S and Bonadona, V and Baurand, A and Faivre, L and Buecher, B and Lasset, C and Gauthier-Villars, M and Damiola, F and Mazoyer, S and Caputo, Sandrine M and Andrieu, N and Stoppa-Lyonnet, D and GEMO Study Collaborators
Frontiers in oncology, ISSN 2234-943X, 2018, Volume 8, pp. 490 - 490
Journal Article
by Hamdi, Yosr and Soucy, P and Kuchenbaeker, K.B and Pastinen, T and it, Arnaud and Lemaçon, A and Adlard, Julian and Aittomäki, Kristiina and Anulis, Irene and Arason, Adalgeir and Arnold, Norbert and Arun, Banu and Azzollini, J and Bane, Anita L and Barjhoux, L and Barrowdale, Daniel and Benítez, Javier and Berthet, Pascaline and Blok, Marinus and Bobolis, Kristie A and Bonadona, Valérie and Bonnani, Bernardo and Bradbury, A.R and Brewer, Carole and Buecher, Bruno and Buys, S.S and Caligo, Maria and Chiquette, J and Chung, Wendy and Claes, Kathleen B.M and Daly, M.B and Damiola, Francesca and Davidson, Rosemarie and Hoya, Miguel and De Leeneer, Kim and Díez, Orland and Ding, Yuan and Dolcetti, Riccardo and Domchek, Susan and Dorfling, Cecilia and Eccles, Diana and Eeles, Ros and Einbeigi, Zakaria and Ejlertsen, Bent and EMBRACE and Engel, Christoph and Gareth Evans, D and Feliubadaló, L and Foretova, Lenka and Fostira, Florentia and Foulkes, W.D and Fountzilas, George and Friedman, Eitan and Frost, Debra and Ganschow, Pamela and Ganz, Patricia A and Garber, Judy and Gayther, Simon and GEMO Study Collaborators and Gerdes, Anne-Marie and Glendon, Gord and Godwin, Anew K and Goldgar, David and Greene, Mark H and Gronwald, Jacek and Hahnen, Eric and Hamann, Ute and Hansen, Thomas and Hart, Stewart and Hays, John and HEBON and Hogervorst, Frans and Hulick, Peter and Imyanitov, Evgeny and Isaacs, Claudine and Izatt, Louise and Jakubowska, Anna and James, Margaret and Janavicius, Ramunas and Jensen, U.B and John, Esther and Joseph, Vijai and Just, W and Kaczmarek, K and Karlan, B.Y and KConFab Investigators and Kets, Marleen and Kirk, Judy and Kriege, M and Laitman, Yael and Laurent, M and Lázaro, Conxi and Leslie, G and Lester, Kathryn and Lesueur, Fabienne and Liljegren, Annelie and Loman, Niklas and Loud, Jennifer and Manoukian, Siranoush and Mariani, M and ...
Breast cancer research and treatment, ISSN 0167-6806, 10/2016, pp. 1 - 18
Purpose: Cis-acting regulatory SNPs resulting in differential allelic expression (DAE) may, in part, explain the underlying phenotypic variation associated... 
Differential allelic expression | Cis-regulatory variants | Genetic modifiers |