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by Kuchenbaecker, Karoline B and McGuffog, Lesley and Barrowdale, Daniel and Lee, Andrew and Soucy, Penny and Dennis, Joe and Domchek, Susan M and Robson, Mark and Spurdle, Amanda B and Ramus, Susan J and Mavaddat, Nasim and Terry, Mary Beth and Neuhausen, Susan L and Schmutzler, Rita Katharina and Simard, Jacques and Pharoah, Paul D.P and Offit, Kenneth and Couch, Fergus J and Chenevix-Trench, Georgia and Easton, Douglas F and Antoniou, Antonis C and Healey, Sue and Lush, Michael and Hamann, Ute and Southey, Melissa and John, Esther M and Chung, Wendy K and Daly, Mary B and Buys, Saundra S and Goldgar, David E and Dorfling, Cecilia M and van Rensburg, Elizabeth J and Ding, Yuan Chun and Ejlertsen, Bent and Gerdes, Anne-Marie and Hansen, Thomas V. O and Slager, Susan and Hallberg, Emily and Benitez, Javier and Osorio, Ana and Cohen, Nancy and Lawler, William and Weitzel, Jeffrey N and Peterlongo, Paolo and Pensotti, Valeria and Dolcetti, Riccardo and Barile, Monica and Bonanni, Bernardo and Azzollini, Jacopo and Manoukian, Siranoush and Peissel, Bernard and Radice, Paolo and Savarese, Antonella and Papi, Laura and Giannini, Giuseppe and Fostira, Florentia and Konstantopoulou, Irene and Adlard, Julian and Brewer, Carole and Cook, Jackie and Davidson, Rosemarie and Eccles, Diana and Eeles, Ros and Ellis, Steve and EMBRACE, EMBRACE and Frost, Debra and Hodgson, Shirley and Izatt, Louise and Lalloo, Fiona and Ong, Kai-ren and Godwin, Andrew K and Arnold, Norbert and Dworniczak, Bernd and Engel, Christoph and Gehrig, Andrea and Hahnen, Eric and Hauke, Jan and Kast, Karin and Meindl, Alfons and Niederacher, Dieter and Varon-Mateeva, Raymonda and Wang-Gohrke, Shan and Wappenschmidt, Barbara and Barjhoux, Laure and Collonge-Rame, Marie-Agne`s and Elan, Camille and GEMO Study Collaborators, Study Collaborators and Golmard, Lisa and Barouk-Simonet, Emmanuelle and Lesueur, Fabienne and Mazoyer, Sylvie and Sokolowska, Joanna and StoppaLyonnet, Dominique and Isaacs, Claudine and Claes, Kathleen B. M and Poppe, Bruce and de la Hoya, Miguel and Garcia-Barberan, Vanesa and Aittomäki, Kristiina and Nevanlinna, Heli and ... and Onkologi och Patologi, MV and Lund University and Division of Clinical Genetics and Oncology and Pathology, MV and Avdelningen för klinisk genetik and BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation and Lunds universitet
Journal of the National Cancer Institute, ISSN 0027-8874, 07/2017, Volume 109, Issue 7, p. djw302
Journal Article
by Phelan, Catherine M and Kuchenbaecker, Karoline B and Tyrer, Jonathan P and Kar, Siddhartha P and Lawrenson, Kate and Winham, Stacey J and Dennis, Joe and Pirie, Ailith and Riggan, Marjorie J and Chornokur, Ganna and Earp, Madalene A and Lyra, Paulo C and Lee, Janet M and Coetzee, Simon and Beesley, Jonathan and McGuffog, Lesley and Soucy, Penny and Dicks, Ed and Lee, Anew and Barrowdale, Daniel and Lecarpentier, Julie and Leslie, Goska and Aalfs, Cora M and Aben, Katja K. H and Adams, Marcia and Adlard, Julian and Anulis, Irene L and Anton-Culver, Hoda and Antonenkova, Natalia and Aravantinos, Gerasimos and Arnold, Norbert and Arun, Banu K and Arver, Brita and Azzollini, Jacopo and Balmaña, Judith and Banerjee, Susana N and Barjhoux, Laure and Barkardottir, Rosa B and Bean, Yukie and Beckmann, Matthias W and Beeghly-Fadiel, Alicia and Benitez, Javier and Bermisheva, Marina and Bernardini, Marcus Q and Birrer, Michael J and Bjorge, Line and Black, Amanda and Blankstein, Kenneth and Blok, Marinus J and Bodelon, Clara and Bogdanova, Natalia and Bojesen, Anders and Bonanni, Bernardo and Borg, Åke and Bradbury, Angela R and Brenton, James D and Brewer, Carole and Brinton, Louise and Broberg, Per and Brooks-Wilson, Angela and Bruinsma, Fiona and Brunet, Joan and Buecher, Bruno and Butzow, Ralf and Buys, Sauna S and Caldes, Trinidad and Caligo, Maria A and Campbell, Ian and Cannioto, Rikki and Carney, Michael E and Cescon, Terence and Chan, Salina B and Chang-Claude, Jenny and Chanock, Stephen and Chen, Xiao Qing and Chiew, Yoke-Eng and Chiquette, Jocelyne and Chung, Wendy K and Claes, Kathleen B. M and Conner, Thomas and Cook, Linda S and Cook, Jackie and Cramer, Daniel W and Cunningham, Julie M and D'Aloisio, Aimee A and Daly, Mary B and Damiola, Francesca and Damirovna, Sakaeva Dina and Dansonka-Mieszkowska, Agnieszka and Dao, Fanny and Davidson, Rosemarie and Defazio, Anna and Delnatte, Capucine and Doheny, Kimberly F and Diez, Orland and Ding, Yuan Chun and Doherty, Jennifer Anne and Domchek, Susan M and Dorfling, Cecilia M and Dörk, Thilo and ... and KConFab Investigators and EMEMBRACE Study and GEMO Study Collaborators and OPAL Study Grp and AOCS Study Grp and HEBON Study and AOCS study group and EMBRACE Study and OPAL study group and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 5, pp. 680 - 691
Journal Article
by Gaudet, Mia and Kircchoff, Tomas and Green, Todd and Vijai, Joseph and Korn, Joshua and Guiducci, Candace and Segrè, Ayellet and McGee, Kate and McGuffog, Lesley and Kartsonaki, Christiana and Morrison, Jonathan and Healey, Sue and Sinilnikova, Olga and Stoppa-Lyonnet, Dominique and Mazoyer, Sylvie and Gauthier-Villars, Marion and Sobol, Hagay and Longy, Michel and Frenay, Marc and Hogervorst, Frans and Rookus, Matti and Collée, Margriet and Hoogerbrugge, Nicoline and Roozendaal, Kees and Piedemonte, Marion and Rubinstein, Wendy and Nerenstone, Stacy and Le, Linda and Blank, Stephanie and Caldes, Trinidad and Hoya, Miguel and Nevanlinna, Heli and Aittomäki, Kristiina and Lazaro, Conxi and Blanco, Ignacio and Arason, Adalgeir and Johannson, Oskar and Barkardottir, Rosa and Devilee, Peter and Olopade, Olofunmilayo and Neuhausen, Susan and Wang, Xianshu and Fredericksen, Zachary and Peterlongo, Paolo and Manoukian, Siranoush and Barile, Monica and Viel, Alessana and Radice, Paolo and Phelan, Catherine and Narod, Steven and Rennert, Gad and Lejbkowicz, Flavio and Flugelman, Anath and Anulis, Irene and Glendon, Gord and Ozcelik, Hilmi and Toland, Amanda and Montagna, Marco and D'Anea, Emma and Friedman, Eitan and Laitman, Yael and Borg, Åke and Beattie, Mary and Ramus, Susan and Domchek, Susan and Nathanson, Katherine and Rebbeck, Timothy and Spurdle, Amanda and Chen, Xiaoqing and Holland, Helene and John, Esther and Hopper, John and Buys, Sauna and Daly, Mary and Southey, Melissa and Terry, Mary-beth and Tung, Nadine and Hansen, Thomas and Nielsen, Finn and Greene, Mark and Mai, Phuong and Osorio, Ana and Duran, M and Anes, Raquel and Benítez, Javier and Weitzel, Jeffrey and Garber, Judy and Hamann, Ute and Peock, Susan and Cook, Margaret and Oliver, Clare and Frost, Debra and Platte, Radka and Evans, Gareth and Lalloo, Fiona and Eeles, Rosalind and Izatt, Louise and Walker, Lisa and Eason, Jacqueline and Barwell, Julian and ... and HEBON Study Collaborators and GEMO Study Collaborators and kConFab and OCGN and EMBRACE and Onkologi och Patologi, MV and Lund University and Oncology and Pathology, MV and Lunds universitet
P L o S Genetics (Print), ISSN 1553-7390, 10/2010, Volume 6, Issue 10, pp. 1 - 12
Journal Article
by Maxwell, Christopher A and Benítez, Javier and Gómez-Baldó, Laia and Osorio, Ana and Bonifaci, Núria and Fernández-Ramires, Ricardo and Costes, Sylvain V and Guinó, Elisabet and Chen, Helen and Evans, Gareth J. R and Mohan, Pooja and Català, Isabel and Petit, Anna and Aguilar, Helena and Villanueva, Alberto and Aytes, Alvaro and Serra-Musach, Jordi and Rennert, Gad and Lejbkowicz, Flavio and Peterlongo, Paolo and Manoukian, Siranoush and Peissel, Bernard and Ripamonti, Carla B and Bonanni, Bernardo and Viel, Alessana and Allavena, Anna and Bernard, Loris and Radice, Paolo and Friedman, Eitan and Kaufman, Bella and Laitman, Yael and Dubrovsky, Maya and Milgrom, Roni and Jakubowska, Anna and Cybulski, Cezary and Gorski, Bohdan and Jaworska, Katarzyna and Durda, Katarzyna and Sukiennicki, Grzegorz and Lubiński, Jan and Shugart, Yin Yao and Domchek, Susan M and Letrero, Richard and Weber, Barbara L and Hogervorst, Frans B. L and Rookus, Matti A and Collee, J. Margriet and Devilee, Peter and Ligtenberg, Marjolijn J and Luijt, Rob B. van der and Aalfs, Cora M and Waisfisz, Quinten and Wijnen, Juul and Roozendaal, Cornelis E. P. van and Easton, Douglas F and Peock, Susan and Cook, Margaret and Oliver, Clare and Frost, Debra and Harrington, Patricia and Evans, D. Gareth and Lalloo, Fiona and Eeles, Rosalind and Izatt, Louise and Chu, Carol and Eccles, Diana and Douglas, Fiona and Brewer, Carole and Nevanlinna, Heli and Heikkinen, Tuomas and Couch, Fergus J and Lindor, Noralane M and Wang, Xianshu and Godwin, Anew K and Caligo, Maria A and Lombardi, Grazia and Loman, Niklas and Karlsson, Per and Ehrencrona, Hans and Wachenfeldt, Anna von and Barkardottir, Rosa Bjork and Hamann, Ute and Rashid, Muhammad U and Lasa, Aiana and Caldés, Trinidad and Anés, Raquel and Schmitt, Michael and Assmann, Volker and Stevens, Kristen and Offit, Kenneth and Curado, João and Tilgner, Hagen and Guigó, Roderic and Aiza, Gemma and Brunet, Joan and Castellsagué, Joan and Martrat, Griselda and Urruticoechea, Ander and Blanco, Ignacio and Tihomirova, Laima and ... and HEBON and EMBRACE and GEMO Study Collaborators and kConFab and BCFR and SWE-BRCA and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinsk genetik and Uppsala universitet
PLoS biology, ISSN 1544-9173, 2011, Volume 9, Issue 11, pp. e1001199 - e1001199
Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation... 
MULTIPLE-MYELOMA | CENTROSOMAL MICROTUBULE NUCLEATION | STEM-CELLS | MUTATION CARRIERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | MITOTIC SPINDLE | ADHERENS JUNCTIONS | PROGENITOR-CELL FATE | BRCA1-DEPENDENT UBIQUITINATION | EXPRESSION SIGNATURE | MAMMARY-GLAND | Epithelial Cells - metabolism | Humans | Receptors, Estrogen - analysis | Breast Neoplasms - metabolism | Aurora Kinase A | Genetic Variation | BRCA1 Protein - metabolism | Hyaluronan Receptors - metabolism | Microtubules - ultrastructure | Genes, BRCA2 | Female | Genes, BRCA1 | Epithelial Cells - cytology | Extracellular Matrix Proteins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Genetic Predisposition to Disease | Breast - cytology | Extracellular Matrix Proteins - genetics | Microtubules - physiology | Genotype | Aurora Kinases | Hyaluronan Receptors - genetics | BRCA1 Protein - genetics | Cell Polarity - genetics | BRCA2 Protein - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Heterozygote | HeLa Cells | BRCA2 Protein - genetics | Confidence intervals | Medical research | Hospitals | Biomedical research | Colleges & universities | Breast cancer | Mutation | Index Medicus | Càncer de mama | Oncogens | Cèl·lules epitelials | Epithelial cells | Oncogenes | Antigens, CD44 | Cell Polarity | Receptors, Estrogen | Protein-Serine-Threonine Kinases | Epithelial Cells | Breast Neoplasms | Life Sciences | Extracellular Matrix Proteins | Microtubules | BRCA2 Protein | Breast | BRCA1 Protein | Cancer | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
Journal Article
by Lesueur, Fabienne and Mebirouk, Noura and Jiao, Yue and Barjhoux, Laure and Belotti, Muriel and Laurent, Maïté and Léone, Mélanie and Houdayer, Claude and Paillerets, Brigitte Bressacde and Vaur, Dominique and Sobol, Hagay and Noguès, Catherine and Longy, Michel and Mortemousque, Isabelle and Fert-Ferrer, Sandra and Mouret-Fourme, Emmanuelle and Pujol, Pascal and Venat-Bouvet, Laurence and Bignon, Yves-Jean and Leroux, Dominique and Coupier, Isabelle and Berthet, Pascaline and Mari, Véronique and Delnatte, Capucine and Gesta, Paul and Collonge-Rame, Marie-Agnès and Giraud, Sophie and Bonadona, Valérie and Baurand, Amandine and Faivre, Laurence and Buecher, Bruno and Lasset, Christine and Gauthier-Villars, Marion and Damiola, Francesca and Mazoyer, Sylvie and Caputo, Sandrine M and Andrieu, Nadine and Stoppa-Lyonnet, Dominique and Lesueur, Fabienne and Mebirouk, Noura and Jiao, Y and Barjhoux, Laure and Belotti, Muriel and Laurent, M and Léone, M and Houdayer, C and Bressac-De Paillerets, B and Vaur, D and Sobol, H and Nogués, C and Longy, M and Mortemousque, I and Fert-Ferrer, S and Mouret-Fourme, E and Pujol, P and Venat-Bouvet, L and Bignon, Y.-J and Leroux, D and Coupier, I and Berthet, P and Mari, V and Delnatte, C and Gesta, P and Collonge-Rame, M.-A and Giraud, S and Bonadona, V and Baurand, A and Faivre, L and Buecher, B and Lasset, C and Gauthier-Villars, M and Damiola, F and Mazoyer, S and Caputo, Sandrine M and Andrieu, N and Stoppa-Lyonnet, D and GEMO Study Collaborators
Frontiers in Oncology, ISSN 2234-943X, 2018, Volume 8, pp. 490 - 490
Journal Article
by Ferreira, Manuel A and Gamazon, Eric R and Al-Ejeh, Fares and Aittomäki, Kristiina and Andrulis, Irene L and Anton-Culver, Hoda and Arason, Adalgeir and Arndt, Volker and Aronson, Kristan J and Arun, Banu K and Asseryanis, Ella and Azzollini, Jacopo and Balmaña, Judith and Barnes, Daniel R and Barrowdale, Daniel and Beckmann, Matthias W and Behrens, Sabine and Benitez, Javier and Bermisheva, Marina and Białkowska, Katarzyna and Blomqvist, Carl and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Borg, Ake and Brauch, Hiltrud and Brenner, Hermann and Broeks, Annegien and Burwinkel, Barbara and Caldés, Trinidad and Caligo, Maria A and Campa, Daniele and Campbell, Ian and Canzian, Federico and Carter, Jonathan and Carter, Brian D and Castelao, Jose E and Chang-Claude, Jenny and Chanock, Stephen J and Christiansen, Hans and Chung, Wendy K and Claes, Kathleen B. M and Clarke, Christine L and Adlard, Julian and Ahmed, Munaza and Barwell, Julian and Brady, Angela and Brewer, Carole and Cook, Jackie and Davidson, Rosemarie and Donaldson, Alan and Eason, Jacqueline and Eeles, Ros and Evans, D. Gareth and Gregory, Helen and Hanson, Helen and Henderson, Alex and Hodgson, Shirley and Izatt, Louise and Kennedy, M. John and Lalloo, Fiona and Miller, Clare and Morrison, Patrick J and Ong, Kai-ren and Perkins, Jo and Porteous, Mary E and Rogers, Mark T and Side, Lucy E and Snape, Katie and Walker, Lisa and Harrington, Patricia A and Arnold, Norbert and Auber, Bernd and Bogdanova-Markov, Nadja and Borde, Julika and Caliebe, Almuth and Ditsch, Nina and Dworniczak, Bernd and Engert, Stefanie and Faust, Ulrike and Gehrig, Andrea and Hahnen, Eric and Hauke, Jan and Hentschel, Julia and Herold, Natalie and Honisch, Ellen and Just, Walter and Kast, Karin and Larsen, Mirjam and Lemke, Johannes and Nguyen, Huu Phuc and Niederacher, Dieter and Ott, Claus-Eric and Platzer, Konrad and Pohl-Rescigno, Esther and Ramser, Juliane and Rhiem, Kerstin and Steinemann, Doris and Sutter, Christian and Varon-Mateeva, Raymonda and ... and BCFR Investigators and ABCTB Investigators and HEBON Investigators and GC-HBOC Study Collaborators and GEMO Study Collaborators and EMBRACE Collaborators
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1741 - 18
Journal Article
ISSN 1018-4813, 2017
Genome-wide studies of patients carrying pathogenic variants (mutations) in BRCA1 or BRCA2 have reported strong associations between single-nucleotide... 
Journal Article
by Qian, Frank and Wang, Shengfeng and Mitchell, Jonathan and McGuffog, Lesley and Barrowdale, Daniel and Leslie, Goska and Oosterwijk, Jan C and Chung, Wendy K and Evans, D Gareth and Engel, Christoph and Kast, Karin and Aalfs, Cora M and Adank, Muriel A and Adlard, Julian and Agnarsson, Bjarni A and Aittomäki, Kristiina and Alducci, Elisa and Andrulis, Irene L and Arun, Banu K and Ausems, Margreet GEM and Azzollini, Jacopo and Barouk-Simonet, Emmanuelle and Barwell, Julian and Belotti, Muriel and Benitez, Javier and Berger, Andreas and Borg, Ake and Bradbury, Angela R and Brunet, Joan and Buys, Saundra S and Caldes, Trinidad and Caligo, Maria A and Campbell, Ian and Caputo, Sandrine M and Chiquette, Jocelyne and Claes, Kathleen BM and Margriet Collée, J and Couch, Fergus J and Coupier, Isabelle and Daly, Mary B and Davidson, Rosemarie and Diez, Orland and Domchek, Susan M and Donaldson, Alan and Dorfling, Cecilia M and Eeles, Ros and Feliubadaló, Lidia and Foretova, Lenka and Fowler, Jeffrey and Friedman, Eitan and Frost, Debra and Ganz, Patricia A and Garber, Judy and Garcia-Barberan, Vanesa and Glendon, Gord and Godwin, Andrew K and Gómez Garcia, Encarna B and Gronwald, Jacek and Hahnen, Eric and Hamann, Ute and Henderson, Alex and Hendricks, Carolyn B and Hopper, John L and Hulick, Peter J and Imyanitov, Evgeny N and Isaacs, Claudine and Izatt, Louise and Izquierdo, Ángel and Jakubowska, Anna and Kaczmarek, Katarzyna and Kang, Eunyoung and Karlan, Beth Y and Kets, Carolien M and Kim, Sung-Won and Kim, Zisun and Kwong, Ava and Laitman, Yael and Lasset, Christine and Hyuk Lee, Min and Won Lee, Jong and Lee, Jihyoun and Lester, Jenny and Lesueur, Fabienne and Loud, Jennifer T and Lubinski, Jan and Mebirouk, Noura and Meijers-Heijboer, Hanne EJ and Meindl, Alfons and Miller, Austin and Montagna, Marco and Mooij, Thea M and Morrison, Patrick J and Mouret-Fourme, Emmanuelle and Nathanson, Katherine L and Neuhausen, Susan L and Nevanlinna, Heli and Niederacher, Dieter and Nielsen, Finn C and Nussbaum, Robert L and Offit, Kenneth and ...
ISSN 0027-8874, 2018
Journal Article