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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 80, Issue 3, pp. 860 - 868
Purpose To evaluate the effectiveness of mitigation of acute ionizing radiation damage by mitochondrion-targeted small molecules. Methods and Materials We... 
Radiology | Hematology, Oncology and Palliative Medicine | Mitigation | Radiation injury | Mitochondrial targeting | Antioxidant | Nitric oxide synthase inhibitor | p53 inhibitor | unclassified drug | hematopoietic stem cell | stroma cell | mouse | clonogenic assay | alkene | mcf 201 89 | radiation protection | survival rate | priority journal | female | human | human tissue | animal cell | animal experiment | article | bone marrow | mitochondrion | controlled study | nitroxide | nonhuman | lung alveolus epithelium | ionizing radiation | OXIDATIVE STRESS | STROMAL CELL-LINES | NITRIC-OXIDE SYNTHASE | IDENTIFICATION | P53 | DELIVERY | IRRADIATION | INHIBITION | ONCOLOGY | SUPEROXIDE-DISMUTASE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | LEAD COMPOUNDS | Cell Survival - drug effects | Whole-Body Irradiation | Enzyme Inhibitors | Tumor Suppressor Protein p53 - antagonists & inhibitors | Humans | Mice, Inbred C57BL | Nitric Oxide Synthase - antagonists & inhibitors | Imidazoles - pharmacology | Mitochondria - drug effects | Radiation Dosage | Cell Line - radiation effects | Cell Line - drug effects | Animals | Radiation Injuries, Experimental - drug therapy | Nitrogen Oxides - pharmacology | Mitochondria - radiation effects | Radiation-Protective Agents - pharmacology | Thiazines - pharmacology | Female | Indoles - pharmacology | Mice | DNA Damage | Radiation Injuries, Experimental - mortality | Antioxidants | Radiation | Universities and colleges | OXYGEN COMPOUNDS | NITRIC OXIDE | MITOCHONDRIA | RADIATION EFFECTS | BONE MARROW | ANIMAL TISSUES | 60 APPLIED LIFE SCIENCES | BIOLOGICAL EFFECTS | NITROGEN OXIDES | DRUGS | VERTEBRATES | RADIOLOGY AND NUCLEAR MEDICINE | BIOLOGICAL RADIATION EFFECTS | MICE | HEMATOPOIETIC SYSTEM | NITROGEN COMPOUNDS | EXTERNAL IRRADIATION | MAMMALS | ANIMALS | WHOLE-BODY IRRADIATION | INJURIES | RODENTS | ORGANIC COMPOUNDS | RADIATION INJURIES | CHALCOGENIDES | ORGANS | PEPTIDES | DISEASES | OXIDES | PROTEINS | BODY | CELL CONSTITUENTS
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2008, Volume 70, Issue 3, pp. 816 - 825
Purpose To evaluate the in vitro radioprotective effect of the mitochondria-targeted hemigramicidin S–conjugated 4-amino-2,2,6,6-tetramethyl-piperidine- N... 
Radiology | Hematology, Oncology and Palliative Medicine | Cytochrome c | Reactive oxygen species | γ-Irradiation | Cardiolipin oxidation | Hemigramicidin S–conjugated nitroxide | Hemigramicidin S-conjugated nitroxide | APOPTOSIS | CARDIOLIPIN | hemigramicidin S-conjugated nitroxide | PERMEABILITY TRANSITION | RESPONSES | INDUCED GENOMIC INSTABILITY | ONCOLOGY | TEMPOL | reactive oxygen species | cardiolipin oxidation | gamma-irradiation | cytochrome c | CYTOCHROME-C RELEASE | IONIZING-RADIATION | SUPEROXIDE-DISMUTASE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CYCLE | Embryonic Stem Cells - metabolism | Gamma Rays | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Ethidium - metabolism | Phosphatidylserines - secretion | G2 Phase - drug effects | Time Factors | Cyclic N-Oxides - pharmacology | Embryonic Stem Cells - radiation effects | Superoxides - metabolism | Cyclic N-Oxides - metabolism | Cell Survival - physiology | Polyethylene Glycols - pharmacology | Cell Survival - drug effects | Cytochromes c - secretion | G2 Phase - physiology | Superoxide Dismutase - pharmacology | Cells, Cultured | Cardiolipins - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Cell Division - drug effects | Cell Division - physiology | Animals | Embryonic Stem Cells - drug effects | Radiation Injuries - prevention & control | Mice | Antioxidants | Sects | Mitochondrial DNA | Nuclear radiation | Index Medicus | OXIDATION | BUILDUP | GAMMA RADIATION | MITOCHONDRIA | INDIUM 125 | ADENOVIRUS | HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY | IRRADIATION | FLUORESCENCE | IN VITRO | RADIOLOGY AND NUCLEAR MEDICINE | CELL CYCLE | MICE | EMBRYONIC CELLS | PIPERIDINES
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2015, Volume 289, Issue 3, pp. 397 - 408
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2011, Volume 408, Issue 1, pp. 45 - 51
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2008, Volume 231, Issue 2, pp. 235 - 240
Single-walled carbon nanotubes (SWCNT) have been introduced into a large number of new technologies and consumer products. The combination of their exceptional... 
Nanoparticles | Lung disease | Inflammation | Oxidative enzymes | Pulmonary injury | oxidative enzymes | CELLS | PULMONARY TOXICITY | CHRONIC GRANULOMATOUS-DISEASE | lung disease | nanoparticles | REACTIVE OXYGEN | MACROPHAGE PHAGOCYTOSIS | inflammation | APOPTOTIC NEUTROPHILS | ENGULFMENT | SPECIES PRODUCTION | PHARMACOLOGY & PHARMACY | pulmonary injury | TOXICOLOGY | PHOSPHATIDYLSERINE | Inflammation - pathology | Apoptosis - drug effects | NADPH Oxidases - metabolism | Male | Fibrosis - metabolism | Lung Diseases - etiology | Nanotubes, Carbon - toxicity | Transforming Growth Factor beta - drug effects | Collagen - drug effects | NADPH Oxidases - genetics | Neutrophils - metabolism | Lung - pathology | Cytokines - metabolism | Occupational Exposure - adverse effects | Mice, Inbred C57BL | Neutrophils - drug effects | Inflammation - etiology | Collagen - metabolism | Animals | Cytokines - drug effects | Fibrosis - etiology | Lung - drug effects | Mice | Lung Diseases - pathology | Transforming Growth Factor beta - metabolism | Oxidases | Biochemical toxicology | Nanotechnology | Fibrosis | Nanotubes | Index Medicus | FIBROSIS | OXIDATION | APOPTOSIS | CARBON | COLLAGEN | INJURIES | MACROPHAGES | INHALATION | LUNGS | NEUTROPHILS | TOXICITY | 60 APPLIED LIFE SCIENCES | LYMPHOKINES | OXIDASES | INFLAMMATION | NANOTUBES | MICE
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