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1. Full Text Erratum to Fluid challenges in intensive care: the FENICE study: A global inception cohort study (Intensive Care Med, (2015), 10.1007/s00134-015-3850-x)
by Cecconi, Maurizio and Hofer, Christoph and Teboul, Jean-Louis and Pettila, Ville and Wilkman, Erika and Molnar, Zsolt and Della Rocca, Giorgio and Aldecoa, Cesar and Artigas, Antonio and Jog, Sameer and Sander, Michael and Spies, Claudia and Lefrant, Jean-Yves and De Backer, Daniel and on behalf of the FENICE Investigators and the ESICM Trial Group, behalf of the FENICE Investigators and the ESICM Trial Group
Intensive Care Medicine, ISSN 0342-4642, 09/2015, Volume 41, Issue 9, pp. 1737 - 1738
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2. Full Text Economic evaluation of a childhood obesity prevention programme for children: Results from the WAVES cluster randomised controlled trial conducted in schools
by Canaway, Alastair and Frew, Emma and Lancashire, Emma and Pallan, Miranda and Hemming, Karla and Adab, Peymane and WAVES trial investigators and WAVES Trial Investigators and on behalf of the WAVES trial investigators
PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 7, p. e0219500
Childhood obesity is a serious public health challenge and schools have been identified as an ideal place to implement prevention interventions. The aim of... 
BENEFIT REGRESSION FRAMEWORK | MENTAL-HEALTH | COST-EFFECTIVENESS ANALYSES | CURVES | MULTIDISCIPLINARY SCIENCES | Prevention | Economic aspects | Evaluation | Student health services | Obesity in children | Physical fitness | Clinical trials | Research | Comparative analysis | Public sector | Intervention | Uncertainty | Physical activity | Control methods | Waves | Elementary schools | Confidence intervals | Randomization | Cost effectiveness | Children | Schools | Public health | Age | Obesity | Medical research | Statistical analysis | Clustering | Cost control | Quality of life | Missing data | Health care expenditures | Lifestyles | Cost analysis
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3. Full Text Effect of Spironolactone on Blood Pressure in Subjects With Resistant Hypertension
by Chapman, Neil and Dobson, Joanna and Wilson, Sarah and Dahlöf, Björn and Sever, Peter S and Wedel, Hans and Poulter, Neil R and Anglo-Scandanavian Cardiac and Anglo-Scandinavian Cardiac Outcomes Trial Investigators and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Hypertension, ISSN 0194-911X, 04/2007, Volume 49, Issue 4, pp. 839 - 845
Spironolactone is recommended as fourth-line therapy for essential hypertension despite few supporting data for this indication. We evaluated the effect among... 
Hypertension | Clinical trial | Blood pressure | Spironolactone | Antihypertensive agents | Aldosterone antagonists | clinical trial | PRIMARY HYPERALDOSTERONISM | blood pressure | EFFICACY | RATIO | antihypertensive agents | PREVALENCE | spironolactone | PRIMARY ALDOSTERONISM | RATES | THERAPY | PERIPHERAL VASCULAR DISEASE | AGENTS | aldosterone antagonists | hypertension | Gynecomastia - chemically induced | Humans | Middle Aged | Mineralocorticoid Receptor Antagonists - adverse effects | Hypertension - drug therapy | Male | Treatment Outcome | Pain - chemically induced | Antihypertensive Agents - therapeutic use | Mineralocorticoid Receptor Antagonists - therapeutic use | Retreatment | Breast - drug effects | Hyperkalemia - chemically induced | Female | Aged | Blood Pressure - drug effects | Spironolactone - therapeutic use | Drug Resistance | Spironolactone - adverse effects | Antihypertensive Agents/therapeutic use | Pain/chemically induced | Aldosterone Antagonists/adverse effects/therapeutic use | MEDICIN OCH HÄLSOVETENSKAP | Spironolactone/adverse effects/therapeutic use | Gynecomastia/chemically induced | Breast/drug effects | Blood Pressure/drug effects | Hyperkalemia/chemically induced | MEDICAL AND HEALTH SCIENCES | Hypertension/drug therapy
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4. Full Text Central Pressure: Variability and Impact of Cardiovascular Risk Factors: The Anglo-Cardiff Collaborative Trial II
by McEniery, Carmel M and Yasmin and McDonnell, Barry and Munnery, Margaret and Wallace, Sharon M and Rowe, Chloe V and Cockcroft, John R and Wilkinson, Ian B and Anglo-Cardiff Collaborative Tr and Anglo-Cardiff Collaborative Trial Investigators
Hypertension, ISSN 0194-911X, 06/2008, Volume 51, Issue 6, pp. 1476 - 1482
Pulse pressure varies throughout the arterial tree, resulting in a gradient between central and peripheral pressure. Factors such as age, heart rate, and... 
Hypertension | Brachial pressure | Central pressure | Cardiovascular risk factors | Pulse pressure amplification | Pulse pressure ratio | AUGMENTATION INDEX | pulse pressure amplification | cardiovascular risk factors | CENTRAL AORTIC PRESSURE | BLOOD-PRESSURE | WAVE VELOCITY | central pressure | AMPLIFICATION | pulse pressure ratio | ARTERIAL STIFFNESS | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | brachial pressure | hypertension | HYPERTENSIVE SUBJECTS | CENTRAL PULSE PRESSURE | Age Distribution | Wales - epidemiology | Humans | Middle Aged | Male | Diabetic Angiopathies - physiopathology | England - epidemiology | Aged, 80 and over | Adult | Female | Blood Pressure - physiology | Hypertension - epidemiology | Hypertension - diagnosis | Blood Pressure Determination | Hypercholesterolemia - epidemiology | Risk Factors | Hypertension - physiopathology | Regression Analysis | Aging - physiology | Smoking - epidemiology | Adolescent | Diabetic Angiopathies - diagnosis | Diabetic Angiopathies - epidemiology | Aged | Aorta - physiology | Brachial Artery - physiology
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5. Full Text Effects of Age, Gender, Obesity, and Diabetes on the Efficacy and Safety of the Selective A2A Agonist Regadenoson Versus Adenosine in Myocardial Perfusion Imaging. Integrated ADVANCE-MPI Trial Results
by Cerqueira, Manuel D and Nguyen, Patricia and Staehr, Peter and Underwood, S. Richard and Iskandrian, Ami E and ADVANCE-MPI Trial Investigators
JACC: Cardiovascular Imaging, ISSN 1936-878X, 05/2008, Volume 1, Issue 3, pp. 307 - 316
Objectives: To compare the effects of age, gender, body mass index, and diabetes on the safety and efficacy of regadenoson stress myocardial perfusion imaging,... 
Predictive Value of Tests | Age Factors | Humans | Middle Aged | Tomography, Emission-Computed, Single-Photon | Image Interpretation, Computer-Assisted | Male | Patient Satisfaction | Adenosine - adverse effects | Aged, 80 and over | Myocardial Ischemia - diagnostic imaging | Myocardial Ischemia - physiopathology | Adult | Female | Diabetes Complications - diagnostic imaging | Purines - adverse effects | Obesity - diagnostic imaging | Pyrazoles - adverse effects | Body Mass Index | Double-Blind Method | Risk Assessment | Obesity - complications | Risk Factors | Myocardium - pathology | Adenosine A2 Receptor Agonists | Myocardial Perfusion Imaging - methods | Myocardial Ischemia - complications | Sex Factors | Aged | Coronary Circulation - drug effects | Index Medicus
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6. Full Text Process evaluation results of a cluster randomised controlled childhood obesity prevention trial: The WAVES study
by Griffin, T.L and Clarke, J.L and Lancashire, E.R and Pallan, Miranda J and Adab, Peymane and Adab, Peymane and Barrett, Tim and Cheng, K.K and Daley, Amanda and Deeks, Jonathan J and Duda, Joan L and Frew, Emma and Gill, Paramjit and Hemming, Karla and Pallan, Miranda J and Parry, Jayne and Ekelund, Ulf and Cade, Janet E and Bhopal, Raj and McGee, Eleanor and Passmore, Sandra and WAVES Study Trial Investigators and WAVES study trial investigators and On behalf of the WAVES study trial investigators
BMC Public Health, ISSN 1471-2458, 08/2017, Volume 17, Issue 1, pp. 681 - 13
Background: Increasing prevalence of childhood obesity and its related consequences emphasises the importance of developing and evaluating interventions aimed... 
Intervention | Primary school | Process evaluation results | Cluster randomised controlled trial | Implementation fidelity | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ASSOCIATIONS | PHYSICAL-ACTIVITY | PROGRAM | Life Style | Cooking | Humans | Male | United Kingdom | Pediatric Obesity - prevention & control | Health Promotion - organization & administration | Exercise | Female | Program Evaluation | School Health Services - organization & administration | Child | Research Design | Prevention | Elementary school students | Obesity in children | Health aspects | Performance evaluation | Health care | Allocations | Physical activity | Parents | Families & family life | Research | Promotion | Waves | Recruitment | Elementary schools | Logbooks | Teachers | Consultation | Children | Physical education | Schools | Public health | Obesity | Evaluation | Triangulation | Health promotion | Tabulation | Data acquisition | Curricula | Workshops | Football | Studies | Researchers | Teaching methods | Heating | Data collection | Collection | Lifestyles | Cost analysis
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7. Full Text Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: The EMBLEM trial
by Tanaka, Atsushi and Shimabukuro, Michio and Okada, Yosuke and Taguchi, Isao and Yamaoka-Tojo, Minako and Tomiyama, Hirofumi and Teragawa, Hiroki and Sugiyama, Seigo and Yoshida, Hisako and Sato, Yasunori and Kawaguchi, Atsushi and Ikehara, Yumi and Machii, Noritaka and Maruhashi, Tatsuya and Shima, Kosuke R and Takamura, Toshinari and Matsuzawa, Yasushi and Kimura, Kazuo and Sakuma, Masashi and Oyama, Jun-ichi and Inoue, Teruo and Higashi, Yukihito and Ueda, Shinichiro and Node, Koichi and EMBLEM Trial Investigators and On Behalf of the EMBLEM Trial Investigators
Cardiovascular Diabetology, ISSN 1475-2840, 04/2017, Volume 16, Issue 1, pp. 48 - 12
Background: Type 2 diabetes mellitus (T2DM) is characterized by systemic metabolic abnormalities and the development of micro- and macrovascular complications,... 
Empagliflozin | Endothelial function | Type 2 diabetes mellitus (T2DM) | Reactive hyperemia peripheral arterial tonometry (RH-PAT) | Sodium glucose cotransporter 2 (SGLT2) inhibitor | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | COTRANSPORTER 2 INHIBITORS | SGLT2 INHIBITOR | HEART-FAILURE | BLOOD-PRESSURE | VASCULAR-DISEASE | ARTERIAL STIFFNESS | EJECTION FRACTION | ENDOCRINOLOGY & METABOLISM | TYPE-2 DIABETES-MELLITUS | CARDIOVASCULAR RISK | Hypoglycemic Agents - therapeutic use | Atherosclerosis - drug therapy | Metformin - therapeutic use | Prospective Studies | Benzhydryl Compounds - administration & dosage | Double-Blind Method | Humans | Middle Aged | Treatment Outcome | Young Adult | Diabetes Mellitus, Type 2 - blood | Drug Therapy, Combination - methods | Glucosides - administration & dosage | Aged, 80 and over | Adult | Glucosides - therapeutic use | Aged | Blood Pressure - drug effects | Diabetes Mellitus, Type 2 - drug therapy | Benzhydryl Compounds - therapeutic use | Endothelial Cells - drug effects | Heart | Drugs | Oxidative stress | Renal function | Pathogenesis | Medical services | Disorders | Clinical trials | Cardiovascular disease | Glucose | Confidence intervals | Design | Randomization | Covariance | Safety engineering | Atherosclerosis | Classification | Stiffness | Blood pressure | Heart diseases | Heart failure | Life expectancy | Complications | Abnormalities | Diabetes mellitus | Markers | Patients | Endothelium | Studies | Side effects | Inhibitors | Life span | Sodium | Arteriosclerosis | Coronary vessels | Insulin resistance | Hyperemia | Diabetes | Smoking | Kidney transplantation
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8. Full Text Early and late effects of clopidogrel in patients with acute coronary syndromes
by Yusuf, Salim and Mehta, Shamir R and Zhao, Feng and Gersh, Bernard J and Commerford, Patrick J and Blumenthal, Mel and Budaj, Andrzej and Wittlinger, Thomas and Fox, Keith A.A and CURE Trial Investigators and Clopidogrel in Unstable angina to prevent Recurrent Events Trial Investigators
Circulation, ISSN 0009-7322, 02/2003, Volume 107, Issue 7, pp. 966 - 972
Background-The risk of ischemic events is high, both early and late after acute coronary syndromes (ACS). We examine the benefits and risks associated with the... 
Prevention | Platelets | Coronary disease | coronary disease | CARDIAC & CARDIOVASCULAR SYSTEMS | GLYCOPROTEIN IIB/IIIA INHIBITORS | METAANALYSIS | MYOCARDIAL-INFARCTION | RANDOMIZED TRIALS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | prevention | platelets | TIROFIBAN | Myocardial Infarction - epidemiology | Myocardial Infarction - mortality | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Secondary Prevention | Angina, Unstable - drug therapy | Ticlopidine - adverse effects | Female | Stroke - epidemiology | Aspirin - therapeutic use | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Myocardial Ischemia - epidemiology | Platelet Aggregation Inhibitors - adverse effects | Acute Disease | Stroke - prevention & control | Double-Blind Method | Hemorrhage - epidemiology | Risk Assessment | Angina, Unstable - mortality | Treatment Outcome | Syndrome | Ticlopidine - analogs & derivatives | Clopidogrel | Myocardial Infarction - prevention & control | Hemorrhage - chemically induced | Kinetics
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9. Full Text Minimal important change and other measurement properties of the Oxford Elbow Score and the Quick Disabilities of the Arm, Shoulder, and Hand in patients with a simple elbow dislocation; validation study alongside the multicenter FuncSiE trial
by Iordens, Gijs I. T and den Hartog, Dennis and Tuinebreijer, Wim E and Eygendaal, Denise and Schep, Niels W. L and Verhofstad, Michael H. J and van Lieshout, Esther M. M and FuncSIE Trial Investigators and FuncSiE Trial Investigators and on behalf of FuncSiE Trial Investigators
PLoS ONE, ISSN 1932-6203, 2017, Volume 12, Issue 9, p. e0182557
Validation study using data from a multicenter, randomized, clinical trial (RCT). To evaluate the reliability, validity, responsiveness, and minimal important... 
RHEUMATOID-ARTHRITIS | DASH OUTCOME QUESTIONNAIRE | REPORTED OUTCOMES | GERMAN VERSION | MULTIDISCIPLINARY SCIENCES | CLINICALLY IMPORTANT DIFFERENCE | RELIABILITY | QUALITY-OF-LIFE | CONSTRUCT-VALIDITY | CROSS-CULTURAL ADAPTATION | HEALTH-STATUS | Disability Evaluation | Reproducibility of Results | Humans | Middle Aged | Self Report | Male | Joint Dislocations - physiopathology | Patient Outcome Assessment | Arm - physiopathology | Shoulder - physiopathology | Hand - physiopathology | Adult | Female | ROC Curve | Surveys and Questionnaires | Elbow Joint - injuries | Joint Dislocations - diagnosis | Change detection | Consistency | Disabilities | Dislocation | Disability | Ethics | Pain | Shoulder | Surgery | Elbow (anatomy) | Reliability analysis | Elbow | Injuries | Performance indices | Medical research | Patients | Trauma | Quality of life | Dislocations | Anchors | Validity | Hospitals | Fractures | Correlation analysis | Rheumatoid arthritis | Minimum inhibitory concentration | Quantitative psychology | Arm
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10. Full Text CONTINUOUS SUBCUTANEOUS INFUSION VERSUS MULTIPLE DOSE INJECTION OF INSULIN FOR NEWLY-DIAGNOSED T1D PAEDIATRIC PATIENTS: A COST UTILITY ANALYSIS
by Ridyard, CH and Blair, J and Hughes, DA and SCIPI Trial Investigators
VALUE IN HEALTH, ISSN 1098-3015, 10/2017, Volume 20, Issue 9, pp. A582 - A582
HEALTH POLICY & SERVICES | ECONOMICS | HEALTH CARE SCIENCES & SERVICES
Conference Proceeding
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11. Full Text PMD58 - Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis
by Ridyard, CH and Blair, J and Hughes, DA and On behalf of the SCIPI Trial Investigators
Value in Health, ISSN 1098-3015, 10/2017, Volume 20, Issue 9, pp. A582 - A582
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12. Full Text PDB43 - Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
by Ridyard, CH and Blair, J and Hughes, DA and On behalf of the SCIPI Trial Investigators
Value in Health, ISSN 1098-3015, 10/2017, Volume 20, Issue 9, pp. A481 - A482
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13. Full Text PMD45 - Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients
by Ridyard, CH and Blair, J and Hughes, DA and On behalf of the SCIPI Trial Investigators
Value in Health, ISSN 1098-3015, 10/2017, Volume 20, Issue 9, pp. A580 - A580
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14. Full Text PUMP-DOWNLOADED INSULIN USAGE FOR THE FIRST 12 MONTHS IN A COHORT OF CHILDREN NEWLY-DIAGNOSED WITH TYPE 1 DIABETES (T1D)
by Ridyard, CH and Blair, J and Hughes, DA and SCIPI Trial Investigators
VALUE IN HEALTH, ISSN 1098-3015, 10/2017, Volume 20, Issue 9, pp. A481 - A482
HEALTH POLICY & SERVICES | ECONOMICS | HEALTH CARE SCIENCES & SERVICES
Conference Proceeding
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15. Full Text PMD102 - Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
by Ridyard, CH and Blair, J and Hughes, DA and On behalf of the SCIPI Trial Investigators
Value in Health, ISSN 1098-3015, 10/2017, Volume 20, Issue 9, pp. A590 - A590
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16. Full Text Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment
by van den Ham, Henk-Jan and Cooper, Jason D and Tomasik, Jakub and Bahn, Sabine and Aerts, Joeri L and Osterhaus, Albert D. M. E and Gruters, Rob A and Andeweg, Arno C and DC-TRN trial investigators and on behalf of the DC-TRN trial investigators
PLoS ONE, ISSN 1932-6203, 02/2018, Volume 13, Issue 2, p. e0192278
Objectives To characterize the host response to dendritic cell-based immunotherapy and subsequent combined antiretroviral therapy (cART) interruption in... 
RESPONSES | ACTIVATION | REV | REPLICATION | THERAPY | TAT | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | CD4(+) T-CELLS | MICROBIAL TRANSLOCATION | NEF | Usage | Messenger RNA | Immunotherapy | Vaccination | Research | HIV infection | Health aspects | Cluster analysis | Therapy | Biotechnology | Plasma | Immunoassay | Regulators | Neurosciences | Control methods | Laboratories | Chemical engineering | Prophylaxis | Chronic infection | Viruses | Infections | Activation | Hormones | Immunity | Blood | Immunity (cell-mediated) | Proteins | Acquired immune deficiency syndrome--AIDS | Antiretroviral agents | Lymphocytes | Human immunodeficiency virus--HIV | Thyroxine | Growth factors | Lymphatic system | Interruption | Cytokines | Dendritic cells | Neutrophils | Principal components analysis | Leukocytes (neutrophilic) | T cell receptors | Exposure | CXCR3 protein | Regression analysis | Antiretroviral therapy | Studies | Infectious diseases | Globulins | Leptin | Chemokines | Dendritic structure | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
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17. Full Text Does Microvolt T-Wave Alternans Testing Predict Ventricular Tachyarrhythmias in Patients With Ischemic Cardiomyopathy and Prophylactic Defibrillators?. The MASTER (Microvolt T Wave Alternans Testing for Risk Stratification of Post-Myocardial Infarction Patients) Trial
by Chow, Theodore and Kereiakes, Dean J and Onufer, John and Woelfel, Alan and Gursoy, Sinan and Peterson, Brett J and Brown, Mark L and Pu, Wenji and Benditt, David G and MASTER Trial Investigators
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2008, Volume 52, Issue 20, pp. 1607 - 1615
Objectives: The purpose of this trial was to determine whether microvolt T-wave alternans (MTWA) predicts ventricular tachyarrhythmic events (VTEs) in... 
sudden death | T-wave alternans | risk stratification | ventricular arrhythmias | defibrillator therapy | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | HEART-FAILURE | PROGNOSTIC VALUE | BENEFIT | IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR | EJECTION FRACTION | DISEASE | SUDDEN CARDIAC DEATH | DYSFUNCTION | Prospective Studies | Humans | Middle Aged | Tachycardia, Ventricular - etiology | Male | Tachycardia, Ventricular - prevention & control | Cardiomyopathies - therapy | Defibrillators, Implantable | Myocardial Ischemia - complications | Tachycardia, Ventricular - diagnosis | Cardiomyopathies - diagnosis | Myocardial Ischemia - therapy | Cardiomyopathies - complications | Female | Aged | Heart Function Tests | Myocardial Ischemia - diagnosis | Cardiac arrhythmia | Heart attacks | Cardiology | Mortality
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18. Full Text The cost-effectiveness of wound-edge protection devices compared to standard care in reducing surgical site infection after laparotomy: An economic evaluation alongside the ROSSINI trial
by Gheorghe, Adrian and Roberts, Tracy E and Pinkney, Thomas D and Bartlett, David C and Morton, Dion and Calvert, Melanie and ROSSINI Trial Investigators and West Midlands Res Collaborative and West Midlands Research Collaborative and on behalf of the West Midlands Research Collaborative and the ROSSINI Trial Investigators
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e95595
Background: Wound-edge protection devices (WEPDs) have been used in surgery for more than 40 years to reduce surgical site infection (SSI). No economic... 
SURGERY | PREVENTION | RANDOMIZED CONTROLLED-TRIAL | MULTIDISCIPLINARY SCIENCES | Quality-Adjusted Life Years | Surgical Wound Infection - prevention & control | Health Care Costs | Cost-Benefit Analysis | Humans | Surgical Wound Infection - economics | United Kingdom | Laparotomy - economics | Laparotomy - instrumentation | Randomized Controlled Trials as Topic | Care and treatment | Surgical wound infections | Diagnosis | Laparotomy | Patient outcomes | Health care | Abdominal surgery | Evaluation | Economic analysis | Sensitivity analysis | Research & development--R&D | Wounds | Infections | Devices | Patients | Primary care | Generalized linear models | Abdomen | Quality of life | Prevention | Ethics | Infectious diseases | Hospitals | Health economics | Collaboration | Surgery | Cost analysis | Monte Carlo simulation | Research & development | R&D
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