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1. Full Text Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
by Fisher, Sheila A and Regueiro, Miguel D and Anderson, Carl A and Prescott, Natalie J and Mathew, Christopher G and Rutgeerts, Paul and Parkes, Miles and Steinhart, A Hillary and Drummond, Hazel and Bitton, Alain and Georges, Michel and Gut, Ivo and Jewell, Derek and Barrett, Jeffrey C and Daly, Mark J and Dewit, Olivier and Bumpstead, Suzannah and Hansoul, Sarah and Hugot, Jean-Pierre and Barmada, M Michael and Xavier, Ramnik J and Libioulle, Cécile and Tremelling, Mark and Laukens, Debby and Datta, Lisa Wu and Kistner, Emily O and Onnie, Clive M and Griffiths, Anne M and Franchimont, Denis and Lathrop, Mark and Nimmo, Elaine and Green, Todd and Mansfield, John and Zelenika, Diana and Deloukas, Panos and Taylor, Kent D and Ahmad, Tariq and de Vos, Martine and Van Gossum, André and Duerr, Richard H and Silverberg, Mark S and Nicolae, Dan L and Rotter, Jerome I and Schumm, L Philip and Cardon, Lon R and Ghori, Jilur and Heath, Simon and Dassopoulos, Themistocles and Vermeire, Severine and Sandor, Cynthia and Satsangi, Jack and Marchini, Jonathan and Gwilliam, Rhian and Louis, Edouard and Rioux, John D and Mni, Myriam and Belaiche, Jacques and Targan, Stephan R and Brant, Steven R and Murtha, Michael T and Cho, Judy H and Wellcome Trust Case Control and NIDDK IBD Genetics Consortium and Belgian-French IBD Consortium and Wellcome Trust Case Control Consortium and the NIDDK IBD Genetics Consortium and the Belgian-French IBD Consortium and the Wellcome Trust Case Control Consortium
Nature Genetics, ISSN 1061-4036, 08/2008, Volume 40, Issue 8, pp. 955 - 962
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene discovery further, we combined data... 
GENETIC-VARIATION | CELLS | VARIANTS | COLITIS | GENETICS & HEREDITY | RISK | LARGE-SCALE | NONSYNONYMOUS SNPS | IL-23 | EXPRESSION | MULTIPLE | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome, Human | Quantitative Trait Loci | Humans | Physiological aspects | Crohn's disease | Genetic aspects | Research | Genetic susceptibility | Risk factors | Inflammatory bowel disease | Studies | Medical research | Genetics | Genomics | Crohns disease | Index Medicus
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2. Full Text Genome-wide association analysis identifies 20 loci that influence adult height
by Weedon, Michael N and Lango, Hana and Lindgren, Cecilia M and Wallace, Chris and Evans, David M and Mangino, Massimo and Freathy, Rachel M and Perry, John R. B and Stevens, Suzanne and Hall, Alistair S and Samani, Nilesh J and Shields, Beverly and Prokopenko, Inga and Farrall, Martin and Dominiczak, Anna and Johnson, Toby and Bergmann, Sven and Beckmann, Jacques S and Vollenweider, Peter and Waterworth, Dawn M and Mooser, Vincent and Palmer, Colin N. A and Morris, Andrew D and Ouwehand, Willem H and Zhao, Jing Hua and Li, Shengxu and Loos, Ruth J. F and Barroso, Inês and Deloukas, Panagiotis and Sandhu, Manjinder S and Wheeler, Eleanor and Soranzo, Nicole and Inouye, Michael and Wareham, Nicholas J and Caulfield, Mark and Munroe, Patricia B and Hattersley, Andrew T and McCarthy, Mark I and Frayling, Timothy M and Diabet Genetics Initiat and Cambridge GEM Consortium and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and Diabetes Genetics Initiative and The Wellcome Trust Case Control Consortium
Nature Genetics, ISSN 1061-4036, 05/2008, Volume 40, Issue 5, pp. 575 - 583
Adult height is a model polygenic trait, but there has been limited success in identifying the genes underlying its normal variation. To identify genetic... 
POPULATION | COHORTS | STATURE | GENETIC ASSOCIATION | SUSCEPTIBILITY | GENETICS & HEREDITY | OSTEOARTHRITIS | BODY HEIGHT | EXPRESSION | STRATIFICATION | HERITABILITY | Extracellular Matrix Proteins - genetics | Humans | Middle Aged | Genotype | Male | Body Height - genetics | Hedgehog Proteins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome, Human | Neoplasm Proteins - genetics | Stature | Quantitative trait loci | Genetic variation | Physiological aspects | Genetic aspects | Research | Identification and classification | Studies | Genetic research | Genetics | Gene loci | Height | Genes | Index Medicus
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3. Full Text A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity
by Timothy M. Frayling and Nicholas J. Timpson and Michael N. Weedon and Eleftheria Zeggini and Rachel M. Freathy and Cecilia M. Lindgren and John R. B. Perry and Katherine S. Elliott and Hana Lango and Nigel W. Rayner and Beverley Shields and Lorna W. Harries and Jeffrey C. Barrett and Sian Ellard and Christopher J. Groves and Bridget Knight and Ann-Marie Patch and Andrew R. Ness and Shah Ebrahim and Debbie A. Lawlor and Susan M. Ring and Yoav Ben-Shlomo and Marjo-Riitta Jarvelin and Ulla Sovio and Amanda J. Bennett and David Melzer and Luigi Ferrucci and Ruth J. F. Loos and Inês Barroso and Nicholas J. Wareham and Fredrik Karpe and Katharine R. Owen and Lon R. Cardon and Mark Walker and Graham A. Hitman and Colin N. A. Palmer and Alex S. F. Doney and Andrew D. Morris and George Davey Smith and Andrew T. Hattersley and Mark I. McCarthy and Wellcome Trust Case Control and The Wellcome Trust Case Control Consortium
Science, ISSN 0036-8075, 5/2007, Volume 316, Issue 5826, pp. 889 - 894
Obesity is a serious international health problem that increases the risk of several common diseases. The genetic factors predisposing to obesity are poorly... 
Mass | Body mass index | Obesity | Average linear density | Reports | Adults | Type 2 diabetes mellitus | Children | Population genetics | Genotypes | Overweight | ENPP1 | GAD2 | MULTIDISCIPLINARY SCIENCES | Body Mass Index | Genetic Predisposition to Disease | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Overweight - genetics | Male | United Kingdom | Obesity - genetics | Case-Control Studies | Birth Weight | Homozygote | Adolescent | Alleles | Adult | Female | Aged | Polymorphism, Single Nucleotide | Adipose Tissue | Child | Infant, Newborn | Cohort Studies | Obesity gene | Research | Diabetes | Body fat | Genomics | Risk factors | Index Medicus
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4. Full Text Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
by Ouwehand, Willem and Keniry, Andrew and Fisher, Sheila A and Jewell, Derek P and Anderson, Carl A and Prescott, Natalie J and Deloukas, Panos and Blaszczyk, Katarzyna and Mansfield, John C and Mathew, Christopher G and Watkins, Nick and Drummond, Hazel and Cummings, Fraser R and Forbes, Alastair and Barrett, Jeffrey C and Ravindrarajah, Radhi and Sanderson, Jeremy and Inouye, Mike and Hunt, Sarah and Nimmo, Elaine R and Johnson, Christopher and Bumpstead, Suzannah and Hanson, Catherine E and Lobo, Alan and Massey, Dunecan and Cardon, Lon and Ewels, Philip and Satsangi, Jack and Tremelling, Mark and Gwilliam, Rhian and Carter, Martyn and Berzuini, Carlo and Lees, Charlie W and Onnie, Clive M and Parkes, Miles and Lewis, Cathryn M and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and the Wellcome Trust Case Control Consortium
Nature Genetics, ISSN 1061-4036, 06/2008, Volume 40, Issue 6, pp. 710 - 712
We report results of a nonsynonymous SNP scan for ulcerative colitis and identify a previously unknown susceptibility locus at ECM1. We also show that several... 
INFLAMMATORY-BOWEL-DISEASE | VARIANTS | IL23R | SUSCEPTIBILITY | GENETICS & HEREDITY | PHENOTYPE | IDENTIFICATION | GENOME-WIDE ASSOCIATION | Biomarkers - metabolism | Crohn Disease - epidemiology | Crohn Disease - genetics | Interleukin-12 Subunit p40 - genetics | Autophagy-Related Proteins | Genetic Predisposition to Disease | Extracellular Matrix Proteins - genetics | Humans | Risk Factors | Colitis, Ulcerative - genetics | Protein-Serine-Threonine Kinases - genetics | Nod2 Signaling Adaptor Protein - genetics | Colitis, Ulcerative - epidemiology | GTP-Binding Proteins - genetics | Receptors, Interleukin - genetics | Case-Control Studies | Homeodomain Proteins - genetics | Carrier Proteins - genetics | HLA-A Antigens - genetics | Polymorphism, Single Nucleotide - genetics | Cohort Studies | Physiological aspects | Crohn's disease | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Risk factors | Ulcerative colitis | Inflammatory bowel disease | Medical research | Biomedical research | Bowel disease | Colorectal cancer | Genetics | Gene loci | Regression analysis | Crohns disease | Index Medicus
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5. Full Text Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes
by Eleftheria Zeggini and Michael N. Weedon and Cecilia M. Lindgren and Timothy M. Frayling and Katherine S. Elliott and Hana Lango and Nicholas J. Timpson and John R. B. Perry and Nigel W. Rayner and Rachel M. Freathy and Jeffrey C. Barrett and Beverley Shields and Andrew P. Morris and Sian Ellard and Christopher J. Groves and Lorna W. Harries and Jonathan L. Marchini and Katharine R. Owen and Beatrice Knight and Lon R. Cardon and Mark Walker and Graham A. Hitman and Andrew D. Morris and Alex S. F. Doney and Mark I. McCarthy and Andrew T. Hattersley and WTCCC and Wellcome Trust Case Control Consortium (WTCCC) and The Wellcome Trust Case Control Consortium (WTCCC)
Science, ISSN 0036-8075, 6/2007, Volume 316, Issue 5829, pp. 1336 - 1341
The molecular mechanisms involved in the development of type 2 diabetes are poorly understood. Starting from genome-wide genotype data for 1924 diabetic cases... 
Medical research | Forestry research | Hospital buildings | Medical genetics | Genetic research | Hospital units | Genetic loci | Reports | Type 2 diabetes mellitus | Human genetics | Research universities | GENE | INSULIN-DEGRADING ENZYME | CDK4 | MULTIDISCIPLINARY SCIENCES | MASS | PANCREAS | MICE | HEX | VARIANT | MAP | Insulin-Like Growth Factor Binding Proteins - genetics | Genetic Predisposition to Disease | Meta-Analysis as Topic | Oligonucleotide Array Sequence Analysis | Introns | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | United Kingdom | Chromosome Mapping | Transcription Factors - genetics | Genes, p16 | Case-Control Studies | Homeodomain Proteins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome, Human | Type 2 diabetes | Genetic aspects | Research | Risk factors | Biomedical research | Cellular biology | Genomics | Diabetes | Molecular biology | Pancreas | Population genetics | Index Medicus
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6. Full Text Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
by Nejentsev, Sergey and Bailey, Rebecca and Hardy, Matthew and Cooper, Jason D and Howson, Joanna M. M and Walker, Neil M and Maier, Lisa M and Ribas, Gloria and King, Erna and Szeszko, Jeffrey and Field, Sarah F and Reynolds, Pamela and Smyth, Deborah and Todd, John A and Hulme, John and Clayton, David G and Masters, Jennifer and Stevens, Helen E and Campbell, R. Duncan and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and The Wellcome Trust Case Control Consortium
Nature, ISSN 0028-0836, 12/2007, Volume 450, Issue 7171, pp. 887 - 892
The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome,... 
DESTRUCTION | NOD MICE | PREDISPOSITION | MULTIDISCIPLINARY SCIENCES | RISK | MELLITUS | ASSOCIATION | CD8 T-CELLS | REGION | REVEALS | INFILTRATION | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Gene Frequency | Humans | Genes, MHC Class I - genetics | Databases, Genetic | Diabetes Mellitus, Type 1 - genetics | Genotype | Case-Control Studies | HLA-DR Antigens - genetics | Genes, MHC Class II - genetics | Sample Size | HLA-DQ Antigens - genetics | HLA-DRB1 Chains | Alleles | HLA-A Antigens - genetics | Polymorphism, Single Nucleotide - genetics | HLA-B Antigens - genetics | HLA-DQ beta-Chains | Genotype & phenotype | Statistical analysis | Genomics | Diabetes | Autoimmune diseases | Gene expression | Chromosomes | Index Medicus
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7. Full Text Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study
by Hernandez-Fuentes, Maria P and Franklin, Christopher and Rebollo-Mesa, Irene and Mollon, Jennifer and Delaney, Florence and Perucha, Esperanza and Stapleton, Caragh and Borrows, Richard and Byrne, Catherine and Cavalleri, Gianpiero and Clarke, Brendan and Clatworthy, Menna Ruth and Feehally, John and Fuggle, Susan and Gagliano, Sarah A and Griffin, Sian and Hammad, Abdul and Higgins, Robert and Jardine, Alan and Keogan, Mary and Leach, Timothy and MacPhee, Iain and Mark, Patrick B and Marsh, James and Maxwell, Peter and McKane, William and McLean, Adam and Newstead, Charles and Augustine, Titus and Phelan, Paul and Powis, Steve and Rowe, Peter and Sheerin, Neil and Solomon, Ellen and Stephens, Henry and Thuraisingham, Raj and Trembath, Richard and Topham, Peter and Vaughan, Robert and Sacks, Steven H and Conlon, Peter and Opelz, Gerhard and Soranzo, Nicole and Weale, Michael E and Lord, Graham M and United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3
ISSN 1600-6135, 2018
United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3
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8. Full Text A network-based approach to prioritize results from genome-wide association studies
by Akula, Nirmala and Baranova, Ancha and Seto, Donald and Solka, Jeffrey and Nalls, Michael A and Singleton, Andrew and Ferrucci, Luigi and Tanaka, Toshiko and Bandinelli, Stefania and Cho, Yoon Shin and Kim, Young Jin and Lee, Jong-Young and Han, Bok-Ghee and McMahon, Francis J and Bipolar Disorder Genome Study BiG and Wellcome Trust Case-Control Consor and Wellcome Trust Case-Control Consortium and Bipolar Disorder Genome Study (BiGS) Consortium and The Wellcome Trust Case-Control Consortium
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 9, pp. e24220 - e24220
Genome-wide association studies (GWAS) are a valuable approach to understanding the genetic basis of complex traits. One of the challenges of GWAS is the... 
PROTEIN NETWORKS | HYPERCATABOLIC PATIENTS | BIOLOGY | MOLECULAR NETWORKS | GENE-EXPRESSION | PATHWAY ANALYSIS | LARGE-SCALE | COMPLEX DISEASES | HARDY-WEINBERG EQUILIBRIUM | COMMON HUMAN-DISEASES | SYSTEMS BIOLOGY | Receptors, Antigen, T-Cell - metabolism | Humans | Crohn Disease - metabolism | Protein Binding | Chemokines - metabolism | Genome-Wide Association Study - methods | Interleukins - metabolism | Algorithms | Genes | Genomics | Physiological aspects | Cellular signal transduction | Genetic aspects | Genetic transcription | Nucleic acids | T cells | Genetic translation | Methods | Protein-protein interactions | Phosphates | Brain | Transcription | Laboratories | Leukemia | Bias | Interleukin | Mental health | Science | Bipolar disorder | Lymphocytes T | Genomes | Biology | Metastasis | Software development tools | Protein turnover | Confidence intervals | Proteins | Consortia | T-cell receptor | Biological effects | Aging | Search engines | Genetics | Source code | Gene expression | Metabolism | Equilibrium | Zinc | Studies | Freeware | Hypotheses | Lymphocytes B | Data sets | Linear algebra | Stem cells | Connectivity | Transduction | Protein interaction | Polygenic inheritance | Prostate cancer | Translation | software | Data processing | Crohn's disease | nucleic acids | Computer programs | Signal transduction | Interleukins | Phosphate | Chemokines | Index Medicus
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