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Archiv der Pharmazie, ISSN 0365-6233, 10/2015, Volume 348, Issue 10, pp. 730 - 742
Tolmetin hydrazide and a novel series of tolmetin hydrazide–hydrazones 4a–l were synthesized in this study. The structures of the new compounds were determined... 
Tolmetin | Colon cancer | Caspase‐3 | Hydrazide–hydrazone | Apoptosis | Caspase-3 | Hydrazide-hydrazone | CHEMISTRY, MEDICINAL | ANTICANCER AGENTS | BIOLOGICAL-ACTIVITIES | TUMOR-CELLS | CHEMISTRY, MULTIDISCIPLINARY | COX-2 EXPRESSION | IN-VITRO | ANTI-HCV | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | COLORECTAL-CANCER | ASPIRIN USE | PHARMACOLOGY & PHARMACY | PRO-APOPTOSIS | Caspase 9 - metabolism | Apoptosis - drug effects | Antineoplastic Agents - chemical synthesis | Colonic Neoplasms - drug therapy | Humans | Caspase 8 - metabolism | Structure-Activity Relationship | Tolmetin - analogs & derivatives | Antineoplastic Agents - metabolism | Dose-Response Relationship, Drug | Tolmetin - pharmacology | MCF-7 Cells | Drug Design | Cyclooxygenase 1 - chemistry | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Tolmetin - metabolism | HCT116 Cells | Hydrazones - chemical synthesis | Hydrazones - metabolism | Cyclooxygenase Inhibitors - pharmacology | Hydrazones - pharmacology | HT29 Cells | Tolmetin - chemical synthesis | Signal Transduction - drug effects | Colonic Neoplasms - pathology | Cyclooxygenase Inhibitors - chemical synthesis | Protein Conformation | Cell Proliferation - drug effects | Colonic Neoplasms - enzymology | Molecular Docking Simulation | Cyclooxygenase 1 - metabolism | Enzyme Activation | Enzymes | Nonsteroidal anti-inflammatory drugs
Journal Article
Journal Article
Archiv der Pharmazie, ISSN 0365-6233, 05/2013, Volume 346, Issue 5, pp. 367 - 379
Journal Article
Journal of Pineal Research, ISSN 0742-3098, 09/2013, Volume 55, Issue 2, pp. 138 - 148
Journal Article
Journal Article
Molecules, ISSN 1420-3049, 03/2013, Volume 18, Issue 3, pp. 3595 - 3614
A series of novel N-(3-substituted aryl/alkyl-4-oxo-1,3-thiazolidin-2-ylidene)-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamides... 
Hepatitis C NS5B | Sulfonylthiourea | Celecoxib | Anticancer | Anti-inflammatory | NS5B POLYMERASE | ACID | CYCLOOXYGENASE-2 | hepatitis C NS5B | sulfonylthiourea | celecoxib | BIOCHEMISTRY & MOLECULAR BIOLOGY | RING-SYSTEMS | CHEMISTRY, MULTIDISCIPLINARY | anticancer | HEPATOCELLULAR-CARCINOMA | HEPATITIS-C VIRUS | POLYMERASE INHIBITORS | PAW EDEMA | anti-inflammatory | LIPID PEROXIDES | PROSTAGLANDIN | Thiazolidines - chemical synthesis | Antiviral Agents - toxicity | Pyrazoles - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Thiazolidines - toxicity | Male | Antineoplastic Agents - toxicity | Antioxidants | Dose-Response Relationship, Drug | Viral Nonstructural Proteins - chemistry | Isothiocyanates - chemistry | Sulfonylurea Compounds - pharmacology | Lipid Peroxidation - drug effects | Female | Antineoplastic Agents - pharmacology | Drug Evaluation, Preclinical | Thiazolidines - pharmacology | Cyclooxygenase 2 Inhibitors - toxicity | Pyrazoles - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Stomach Ulcer - chemically induced | Antiviral Agents - pharmacology | Catalytic Domain | Cyclooxygenase 2 Inhibitors - pharmacology | Stomach Ulcer - drug therapy | Sulfonylurea Compounds - chemical synthesis | Sulfonylurea Compounds - toxicity | Edema - drug therapy | Sulfonamides - pharmacology | Sulfonamides - chemical synthesis | Hepacivirus - enzymology | Animals | Hindlimb - pathology | Pyrazoles - toxicity | Antiviral Agents - chemical synthesis | Cell Line, Tumor | Protein Binding | Hindlimb - drug effects | Sulfonamides - toxicity | Mice | Mice, Inbred BALB C | Edema - chemically induced | Oxidative Stress - drug effects | Viral Nonstructural Proteins - antagonists & inhibitors
Journal Article
Peptides, ISSN 0196-9781, 04/2016, Volume 78, pp. 1 - 10
•Nesfatin-1 improved oxidative skin injury induced by surgical wound.•Nesfatin-1 facilitated wound healing in non-diabetic and diabetic rats.•Nesfatin-1... 
Surgical wound | Hyperglycaemia | Nesfatin-1 | Neutrophil infiltration | Vascular endothelial growth factor (VEGF) | Oxidative injury | ULCERS | IMMUNOREACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR EXPRESSION | DAMAGE | BETA | INSULIN | GLUTATHIONE | ANTIOXIDANT | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGY & PHARMACY | STRESS | ENDOTHELIAL GROWTH-FACTOR | Neovascularization, Physiologic - drug effects | Diabetes Mellitus, Experimental - drug therapy | Glutathione - metabolism | Streptozocin | Caspase 3 - immunology | Hyperglycemia - complications | Male | Skin - injuries | Vascular Endothelial Growth Factor A - genetics | Hyperglycemia - drug therapy | Interleukin-1beta - blood | Transforming Growth Factor beta1 - immunology | Hyperglycemia - chemically induced | Surgical Wound - complications | Interleukin-6 - blood | Surgical Wound - pathology | Caspase 3 - genetics | Nerve Tissue Proteins - pharmacology | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - complications | Transforming Growth Factor beta1 - blood | Wound Healing - drug effects | Neutrophil Infiltration - drug effects | Skin - immunology | Malondialdehyde - metabolism | DNA-Binding Proteins - pharmacology | Peroxidase - immunology | Oxidation-Reduction | Hyperglycemia - immunology | Injections, Intraperitoneal | Interleukin-1beta - immunology | Rats | Vascular Endothelial Growth Factor A - immunology | Antioxidants - pharmacology | Rats, Sprague-Dawley | Diabetes Mellitus, Experimental - immunology | Glutathione - immunology | Animals | Surgical Wound - immunology | Malondialdehyde - immunology | Interleukin-6 - immunology | Peroxidase - genetics | Calcium-Binding Proteins - pharmacology | Surgical Wound - drug therapy | Skin - drug effects | Skin | College teachers | Surgical clinics | Vascular endothelial growth factor | Paraffins | Hyperglycemia | Wound healing | Peptides | Activation | Skin injuries | Analysis of variance
Journal Article
Psychiatry and Clinical Psychopharmacology, ISSN 2475-0573, 07/2019, Volume 29, Issue 3, pp. 239 - 243
Journal Article