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Studia mediaevalia Bohemica, ISSN 1804-0977, 2014, Volume 6, Issue 2, pp. 303 - 306
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e110291
Thiosemicarbazones (TSCs) are an interesting class of ligands that show a diverse range of biological activity, including antifungal, anti-viral and... 
METASTASIS SUPPRESSOR | SELECTIVE ANTINEOPLASTIC ACTIVITY | ANTIPROLIFERATIVE ACTIVITY | ATOMIC PHYSICOCHEMICAL PARAMETERS | RIBONUCLEOTIDE REDUCTASE INHIBITOR | PHASE-I TRIAL | MULTIDISCIPLINARY SCIENCES | 3-AMINOPYRIDINE-2-CARBOXALDEHYDE THIOSEMICARBAZONE | REDOX ACTIVITY | IRON OVERLOAD DISEASE | ANTITUMOR-ACTIVITY | Antineoplastic Agents - chemical synthesis | Humans | Iron - chemistry | Thiosemicarbazones - chemical synthesis | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Ascorbic Acid - metabolism | Thiosemicarbazones - chemistry | Drug Design | Oxidation-Reduction - drug effects | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Biological Transport - drug effects | Cell Proliferation - drug effects | Thiosemicarbazones - pharmacology | Care and treatment | Nitrogen | Surgery | Cancer | Reactive oxygen species | Ascorbic acid | Fungicides | Clinical trials | Iron | Structure-activity relationships | Kinases | Cancer therapies | Anticancer properties | Biological effects | Immunology | Ribonucleotide reductase | Antitumor agents | Piperazine | Oxidation | Sulfur | Coordination compounds | Antiviral agents | Enzymes | Fragments | Interdisciplinary aspects | Metabolism | Biological activity | Pathology | Morpholine | Chemistry | Pharmacy | In vivo methods and tests | Chelating agents | Alzheimers disease
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 03/2013, Volume 18, Issue 8, pp. 899 - 929
Significance: Anthracyclines (doxorubicin, daunorubicin, or epirubicin) rank among the most effective anticancer drugs, but their clinical usefulness is... 
Forum Review Articles | DOXORUBICIN-INDUCED CARDIOTOXICITY | ADVANCED BREAST-CANCER | SPONTANEOUSLY HYPERTENSIVE-RATS | MANGANESE SUPEROXIDE-DISMUTASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADRIAMYCIN-INDUCED CARDIOMYOPATHY | ACUTE LYMPHOBLASTIC-LEUKEMIA | ENDOCRINOLOGY & METABOLISM | SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE | MITOCHONDRIAL CALCIUM HOMEOSTASIS | CONGESTIVE-HEART-FAILURE | FREE-RADICAL FORMATION | Anthracyclines - adverse effects | Reactive Oxygen Species - metabolism | Antioxidants - chemistry | Oxidative Stress | Humans | Metals - adverse effects | Razoxane - pharmacology | Anthracyclines - pharmacology | Antineoplastic Agents - adverse effects | Cardiotonic Agents - adverse effects | Myocardium - metabolism | Antineoplastic Agents - pharmacology | Razoxane - chemistry | Chelating Agents - adverse effects | Anthracyclines - chemistry | Oxidation-Reduction | Signal Transduction | Chelating Agents - chemistry | Cardiotonic Agents - chemistry | Antioxidants - pharmacology | Cardiotonic Agents - pharmacology | Chelating Agents - pharmacology | Antineoplastic Agents - chemistry | Razoxane - adverse effects | Heart - drug effects | Complications and side effects | Oxidative stress | Anthracyclines | Oxidation-reduction reaction | Chemical reactions | Dosage and administration | Research | Index Medicus | Forum Review
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2013, Volume 165, Issue 2, pp. 91 - 100
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4524 - 12
Sobuzoxane (MST-16) is an approved anticancer agent, a pro-drug of bisdioxopiperazine analog ICRF154. Due to the structural similarity of ICRF-154 to... 
CARDIOPROTECTIVE DRUG DEXRAZOXANE | AGENT | TOPOISOMERASE-II | HUMAN PLASMA | MULTIDISCIPLINARY SCIENCES | HYDROLYSIS-ACTIVATION | MST-16 | ION | CARDIOMYOCYTES | ANTITUMOR | BIS(2,6-DIOXOPIPERAZINE) | Heart | Cell culture | Ammonium | Razoxane | Acidification | Data processing | Edetic acid | Methanol
Journal Article
Pharmacy (Basel, Switzerland), ISSN 2226-4787, 10/2017, Volume 5, Issue 4, p. 54
The PHARMINE ("Pharmacy Education in Europe") project studied the organisation of pharmacy education, practice and legislation in the European Union (EU) with... 
Curricula | Health education | Education | Drug stores | Professions | pharmacy | practice | Czech Republic | education
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 09/2014, Volume 74, pp. 210 - 221
Oxidative stress is a common denominator of numerous cardiovascular disorders. Free cellular iron catalyzes the formation of highly toxic hydroxyl radicals,... 
Deferasirox | Iron chelation | Prochelator | Free radicals | Salicylaldehyde isonicotinoyl hydrazone | ICL670A | BSIH | APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOTOXICITY | DAMAGE | CELL-DEATH | LABILE IRON | IN-VIVO | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | HYDROGEN-PEROXIDE | STRESS | Rats, Wistar | Apoptosis - drug effects | Triazoles - chemistry | Benzoates - chemistry | Semicarbazones - chemistry | Boronic Acids - chemistry | Isonicotinic Acids - chemistry | Mitochondria, Heart - drug effects | Membrane Potential, Mitochondrial - drug effects | Iron Chelating Agents - chemistry | Isonicotinic Acids - pharmacology | Aldehydes - pharmacology | Cytoprotection | Boron Compounds - chemistry | Boron Compounds - pharmacology | Cell Line | Iron - chemistry | Rats | Iron - metabolism | Hydrazones - chemistry | Hydrazones - pharmacology | Hydrogen Peroxide - metabolism | Triazoles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Iron Chelating Agents - pharmacology | Mitochondria, Heart - physiology | Myocytes, Cardiac - physiology | Cell Membrane Permeability - drug effects | Benzoates - pharmacology | Semicarbazones - pharmacology | Oxidative Stress - drug effects | Aldehydes - chemistry | Boronic Acids - pharmacology | Prevention | Oxidative stress | Hydrogen peroxide | Comparative analysis | Index Medicus | iron chelation | deferasirox (ICL670A) | prochelator | salicylaldehyde isonicotinoyl hydrazone (SIH)
Journal Article
Journal Article
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