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Tetrahedron: Asymmetry, ISSN 0957-4166, 2005, Volume 16, Issue 16, pp. 2778 - 2783
The enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione 1 to either of the corresponding... 
ORGANIC-SYNTHESIS | SEROTONIN RECEPTORS | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | BAKERS-YEAST | CHEMISTRY, INORGANIC & NUCLEAR | BUSPIRONE | METABOLISM | ALCOHOL-DEHYDROGENASE | STEREOCHEMICAL CONTROL | ENZYMES | ASYMMETRIC REDUCTION | 5-HT1A RECEPTOR AFFINITY | Enantiomers
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 2005, Volume 16, Issue 16, pp. 2711 - 2716
6-Hydroxybuspirone is an active metabolite of the antianxiety drug buspirone. The ( R)- and ( S)-enantiomers of 6-hydroxybuspirone were prepared using an... 
CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | BUSPIRONE | METABOLISM | PHARMACOLOGY | CHEMISTRY, INORGANIC & NUCLEAR | Hydroxylation | Enzymes
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 07/2004, Volume 8, Issue 4, pp. 616 - 623
The development of a safe and scalable oxidation process for the hydroxylation of the azapirone psychotropic agent buspirone (1) to furnish 6-hydroxybuspirone... 
CHEMISTRY, ORGANIC | BUSPIRONE | KETONES | CHEMISTRY, MEDICINAL
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1991, Volume 32, Issue 29, pp. 3441 - 3444
A wide variety of easily accesible 1,3-cyclohexanediones are readily transformed to substituted dimethyl resorcinols with iodine and methanol. A wide variety... 
CHEMISTRY, ORGANIC
Journal Article
The FASEB journal, ISSN 0892-6638, 2007, Volume 21, Issue 6, pp. LB83 - LB83
C‐C chemokine receptor 2b (CCR2b) and its ligand, monocyte chemoattractant protein‐1 (MCP‐1), have been implicated in chronic pain. Antagonists of CCR2b are... 
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 2003, Volume 14, Issue 22, pp. 3569 - 3574
Asymmetric cyclopropanation of styrene 1 (as the limiting reagent) was demonstrated using excess ethyl diazoacetate and catalytic Ru(ip-Pybox). Selective... 
CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | OLEFINS | CATALYST | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
ACS Symposium Series, ISSN 0097-6156, 2014, Volume 1181, pp. 235 - 244
Conference Proceeding
Tetrahedron Letters, ISSN 0040-4039, 1990, Volume 31, Issue 4, pp. 481 - 484
A wide variety of easily accessible Hagemann's esters are converted to p-methoxybenzoates with iodine and methanol. © 1990. 
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 01/2003, Volume 7, Issue 1, pp. 25 - 27
The final step of the semisynthetic route to paclitaxel involves cleavage of the triethylsilyl (TES) protecting group from the C-7 hydroxyl group. Paclitaxel... 
CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL
Journal Article
12/2009
Disclosed herein are polynucleotides encoding a chimeric C-C chemokine receptor 2B, the encoded polypeptides thereof and methods of making and using said... 
METALLURGY | PEPTIDES | ORGANIC CHEMISTRY | CHEMISTRY
Patent
09/2009
Disclosed herein are polynucleotides encoding a chimeric C-C chemokine receptor 2B, the encoded polypeptides thereof, and methods of making and using said... 
Patent
Organic Process Research & Development, ISSN 1083-6160, 05/2002, Volume 6, Issue 3, pp. 301 - 303
A practical procedure for the efficient removal of pinanol from the reaction mixture has been developed. The process was based on the observation that pinanol... 
CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL | CARBOCYCLIC THYMIDINE
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1990, Volume 31, Issue 4, pp. 481 - 484
A wide variety of easily accessible Hagemann's esters are converted to p-methoxybenzoates with iodine and methanol. A wide variety of easily accessible... 
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 08/1990, Volume 55, Issue 17, pp. 5078 - 5088
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 07/1997, Volume 1, Issue 4, pp. 315 - 319
A regioisomeric impurity is routinely formed during preparation of the first intermediate of the fosinopril sodium side chain. This first step, the... 
CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL
Journal Article
06/2005, 7
"PROCESSO APERFEIçOADO PARA HIDROXIAZAPIRONAS". A presente invenção descreve um processo para preparação de hidroxiazapironas da Fórmula (I) a partir de... 
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
2005 AIChE Spring National Meeting, Conference Proceedings, 2005, pp. 3911 - 3918
Conference Proceeding
Tetrahedron Letters, ISSN 0040-4039, 1987, Volume 28, Issue 25, pp. 2799 - 2800
Tricyclic lactone 4 was produced in one step from acetoacetate 6 which was prepared from α-ionone. The acetoacetate of 1 underwent a double cyclization... 
Journal Article
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