X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (143) 143
pharmacology & pharmacy (124) 124
models, biological (91) 91
pharmacokinetics (86) 86
index medicus (84) 84
male (58) 58
pharmacy (55) 55
pharmacology/toxicology (52) 52
biomedicine (47) 47
female (47) 47
biochemistry, general (45) 45
adult (43) 43
computer simulation (41) 41
biomedical engineering (40) 40
analysis (37) 37
animals (33) 33
population pharmacokinetics (33) 33
middle aged (31) 31
veterinary medicine (30) 30
kinetics (29) 29
administration, oral (28) 28
pharmacodynamics (26) 26
algorithms (24) 24
dose-response relationship, drug (21) 21
pharmacology (21) 21
tissue distribution (21) 21
child (20) 20
nonmem (20) 20
aged (19) 19
time factors (19) 19
absorption (18) 18
adolescent (18) 18
drug interactions (18) 18
rats (18) 18
pharmaceutical preparations - metabolism (15) 15
bayes theorem (14) 14
biological availability (14) 14
child, preschool (14) 14
models, statistical (14) 14
nonlinear dynamics (14) 14
research design (14) 14
fisher information matrix (12) 12
infant (12) 12
injections, intravenous (12) 12
pbpk (12) 12
software (12) 12
studies (12) 12
area under curve (11) 11
bioavailability (11) 11
chemistry, multidisciplinary (11) 11
children (11) 11
modelling (11) 11
optimal design (11) 11
permeability (11) 11
pharmaceutical preparations - administration & dosage (11) 11
population (11) 11
statistics & probability (11) 11
clinical trials (10) 10
drug development (10) 10
medical law (10) 10
oncology (10) 10
parameter-estimation (10) 10
pharmaceutical sciences (10) 10
simulation (10) 10
toxicology (10) 10
young adult (10) 10
bayesian analysis (9) 9
medical and health sciences (9) 9
medicin och hälsovetenskap (9) 9
oral bioavailability (9) 9
parameter estimation (9) 9
protein binding (9) 9
sample size (9) 9
basic medicine (8) 8
cancer (8) 8
cytochrome p-450 (8) 8
double-blind method (8) 8
linear models (8) 8
medicinska och farmaceutiska grundvetenskaper (8) 8
metabolism (8) 8
metabolites (8) 8
microbiology (8) 8
physiologically-based pharmacokinetics (8) 8
prediction (8) 8
variability (8) 8
administration, intravenous (7) 7
biopharmaceutics (7) 7
chemotherapy (7) 7
chromatography, high pressure liquid (7) 7
drug administration schedule (7) 7
farmaceutiska vetenskaper (7) 7
forecasting (7) 7
half-life (7) 7
implementation (7) 7
infusions, intravenous (7) 7
intestinal absorption (7) 7
liver - metabolism (7) 7
medicine (7) 7
models, theoretical (7) 7
reproducibility of results (7) 7
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Pharmacokinetics and Pharmacodynamics, ISSN 1567-567X, 2/2016, Volume 43, Issue 1, pp. 111 - 122
... Lavielle 1 • Leon Aarons 2 Received: 27 July 2015 / Accepted: 26 November 2015 / Published online: 10 December 2015 Springer Science+Business Media New York 2015... 
Biomedical Engineering | Biochemistry, general | Parameter estimation | Biomedicine | Structural identifiability | Pharmacy | Practical identifiability | Veterinary Medicine | Mixed effects model | Pharmacology/Toxicology | Pharmacokinetics | Model identifiability | Likelihood Functions | Algorithms | Computer Simulation | Humans | Population | Models, Statistical
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 1/2015, Volume 32, Issue 1, pp. 144 - 157
Journal Article
Pharmaceutical research, ISSN 1573-904X, 2014, Volume 32, Issue 6, pp. 1864 - 1883
... an Integrated Population PBPK Approach Nikolaos T samandouras & Gemma Dickinson & Yingying Guo & Stephen Hall & Amin Rostami-Hodjegan & Aleksandra Galetin & Leon Aarons... 
Biochemistry, general | Biomedical Engineering | drug-drug interactions | Biomedicine | Pharmacy | PBPK | simvastatin | Medical Law | population model | Pharmacology/Toxicology | OATP1B1 | HYDROXY ACID | VARIANTS | DRUG-INTERACTIONS | "simvastatin" | QUANTIFICATION | IN-VITRO DATA | "population model" | "OATP1B1" | STATINS | CHEMISTRY, MULTIDISCIPLINARY | DISPOSITION | PRIOR DISTRIBUTIONS | "PBPK" | PHARMACOLOGY & PHARMACY | "drug-drug interactions" | PRAVASTATIN | INHIBITORS | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Activation, Metabolic | Cytochrome P-450 Enzyme Inhibitors - therapeutic use | Simvastatin - adverse effects | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood | Biological Availability | Muscle, Skeletal - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - chemistry | Healthy Volunteers | Simvastatin - blood | Organic Anion Transporters - metabolism | Tissue Distribution | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Drug Interactions | Liver - drug effects | Muscle, Skeletal - drug effects | Muscular Diseases - chemically induced | Pharmacogenetics | Reproducibility of Results | Simvastatin - chemistry | Muscular Diseases - metabolism | Simvastatin - administration & dosage | Liver - metabolism | Simvastatin - pharmacokinetics | Simvastatin - analogs & derivatives | Polymorphism, Genetic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Models, Biological | Solute Carrier Organic Anion Transporter Family Member 1b1 | Metabolites | Simvastatin | Drug interactions | Liver | Cytochrome P-450 | Antilipemic agents | Side effects | Pharmacology | Kinetics | Statins | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 02/2011, Volume 31, Issue 2, pp. 439 - 447
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 1/2019, Volume 58, Issue 1, pp. 131 - 138
... Pharmacokinetic Covariate Models Sebastiaan C. Goulooze 1 • Swantje Vo ¨ller 1 • Pyry A. J. Va ¨litalo 1 • Elisa A. M. Calvier 1 • Leon Aarons 2 • Elke H. J. Krekels 1... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | PHARMACOLOGY & PHARMACY | OBESITY | DIAGNOSTICS | SIZE | Body Weight | Models, Biological | Humans | Phenobarbital - pharmacokinetics | Adult | Pharmacokinetics | Infant, Newborn | Obesity - metabolism
Journal Article