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Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 509 - 509
Abstract Background: Sickle cell disease (SCD) is a genetic disorder caused by a mutated hemoglobin S (HbS) that polymerizes in the deoxygenated state and... 
Journal Article
Lancet, The, ISSN 0140-6736, 2017, Volume 390, Issue 10091, pp. 311 - 323
Summary Sickle cell disease is a common and life-threatening haematological disorder that affects millions of people worldwide. Abnormal sickle-shaped... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | PULMONARY-HYPERTENSION | CLINICAL-TRIAL | SUB-SAHARAN AFRICA | FETAL-HEMOGLOBIN | EARLY-CHILDHOOD MORTALITY | TRANSCRANIAL DOPPLER ULTRASONOGRAPHY | TRANSFUSION-TRANSMITTED INFECTIONS | IRON OVERLOAD | YOUNG-CHILDREN | Hemolysis | Antisickling Agents - therapeutic use | Pregnancy Complications, Hematologic - prevention & control | Stroke - prevention & control | Anemia, Sickle Cell - complications | Humans | Pregnancy | Anemia, Sickle Cell - therapy | Global Burden of Disease | Stem Cell Transplantation - methods | Stroke - etiology | Cerebrovascular Disorders - prevention & control | Point-of-Care Systems | Iron Overload - therapy | Female | Hydroxyurea - therapeutic use | Anemia, Sickle Cell - diagnosis | Chronic Disease | Early Diagnosis | Hemolytic Plaque Technique | Blood Transfusion - methods | Genetic Therapy - methods | Prevention | Transplantation | Diagnostic imaging | Sickle cell anemia | Mortality | Stem cells | Occlusion | Erythrocytes | Iron | Pain | Ischemia | Penicillin | Hemoglobin | Sickle cell disease | Genetic modification | Stroke | Hematology | Anemia | Vessels | Blood vessels | Medical screening | Disease control | Morbidity | Blood flow | Magnetic resonance imaging | Antibiotics | Medical prognosis | Diagnostic systems | Chelating agents | Gene therapy | Risk management
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2015, Volume 33, Issue 15_suppl, pp. e21011 - e21011
Journal Article
Contemporary Clinical Trials, ISSN 1551-7144, 10/2019, Volume 85, p. 105835
An unmet need for therapies exists to reduce sickle cell disease (SCD) complications in pediatric patients. Activated platelets contribute to the formation of... 
Antiplatelet therapy | Vaso-occlusive crisis | Sickle cell disease | Ticagrelor | Pediatric
Journal Article
Science Translational Medicine, ISSN 1946-6234, 03/2014, Volume 6, Issue 227, pp. 227ra33 - 227ra33
Journal Article
Thalassemia Reports, ISSN 2039-4357, 03/2013, Volume 3, Issue 1s, pp. 16 - e16
Oral presentation is available online 
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 998 - 998
Abstract Abstract 998 Fetal hemoglobin (Hb F) induction is an effective therapeutic strategy in SCD. Widespread use of hydroxyurea (HU), the only approved... 
Journal Article
Cochrane Database of Systematic Reviews, 10/2016, Volume 2016, Issue 10
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2016, Volume 374, Issue 7, pp. 625 - 635
Journal Article
Blood, ISSN 0006-4971, 04/2010, Volume 115, Issue 14, pp. 2981 - 2982
Journal Article
Blood, ISSN 0006-4971, 11/2009, Volume 114, Issue 22, pp. 1510 - 1510
Abstract Abstract 1510 Poster Board I-533 Background Chronic blood transfusion is currently the standard of care for primary and secondary stroke prevention in... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5163 - 5163
Abstract Background: Cerebral sinus venous thrombosis (CSVT) is a serious complication of childhood acute lymphoblastic leukemia (ALL) therapy. No universal... 
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2019, Volume 381, Issue 6, pp. 509 - 519
In a trial evaluating two daily-dose levels of voxelotor, which binds to sickle hemoglobin and prevents polymerization under hypoxic conditions, hemoglobin... 
HEMOGLOBIN | MEDICINE, GENERAL & INTERNAL | DEATH | GBT440 | Laboratories | Anemia | Oral administration | Polymerization | Thalassemia | Hydroxyurea | Reticulocytes | FDA approval | Bilirubin | Manuscripts | Motivation | Hemoglobin | Adults | Sickle cell disease | Drug dosages | Age | Pharmaceuticals
Journal Article
Journal Article