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1. Full Text Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data
by Guinney, Justin, PhD and Wang, Tao, PhD and Laajala, Teemu D, MSc and Winner, Kimberly Kanigel, PhD and Bare, J Christopher, BS and Neto, Elias Chaibub, PhD and Khan, Suleiman A, PhD and Peddinti, Gopal, PhD and Airola, Antti, PhD and Pahikkala, Tapio, PhD and Mirtti, Tuomas, MD and Yu, Thomas, BS and Bot, Brian M, MS and Shen, Liji, PhD and Abdallah, Kald, MD and Norman, Thea, PhD and Friend, Stephen, MD and Stolovitzky, Gustavo, PhD and Soule, Howard, PhD and Sweeney, Christopher J, MBBS and Ryan, Charles J, Prof and Scher, Howard I, Prof and Sartor, Oliver, Prof and Xie, Yang, PhD and Aittokallio, Tero, Prof and Zhou, Fang Liz, MD and Costello, James C, Dr and Prostate Canc Challenge DREAM Comm and Prostate Cancer Challenge DREAM Community
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 1, pp. 132 - 142
Summary Background Improvements to prognostic models in metastatic castration-resistant prostate cancer have the potential to augment clinical trial design and... 
Hematology, Oncology and Palliative Medicine | PREDNISONE | PLACEBO | ONCOLOGY | PHASE-III | MEN | DOUBLE-BLIND | COMBINATION | DOCETAXEL | CHEMOTHERAPY | ENZALUTAMIDE | ABIRATERONE | Crowdsourcing | Prednisone - administration & dosage | Prognosis | Follow-Up Studies | Humans | Middle Aged | Docetaxel | Male | Survival Rate | Models, Statistical | Prostatic Neoplasms, Castration-Resistant - drug therapy | Young Adult | Prostatic Neoplasms, Castration-Resistant - secondary | Taxoids - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Bayes Theorem | Nomograms | Adult | Aged | Prostatic Neoplasms, Castration-Resistant - mortality | Neoplasm Staging | Clinical trials | Models | Metastasis | Scientists | Patient outcomes | Prostate cancer
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2. Full Text Estimation of tumour regression and growth rates during treatment in patients with advanced prostate cancer: a retrospective analysis
by Wilkerson, Julia, MSc and Abdallah, Kald, MD and Hugh-Jones, Charles, MD and Curt, Greg, MD and Rothenberg, Mace, MD and Simantov, Ronit, MD and Murphy, Martin, PhD and Morrell, Joseph, BA and Beetsch, Joel, PhD and Sargent, Daniel J, Prof and Scher, Howard I, Prof and Lebowitz, Peter, MD and Simon, Richard, DSc and Stein, Wilfred D, Prof and Bates, Susan E, Prof and Fojo, Tito, Prof
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 1, pp. 143 - 154
Summary Background We applied mathematical models to clinical trial data available at Project Data Sphere LLC (Cary, NC, USA), a non-profit universal access... 
Hematology, Oncology and Palliative Medicine | CELL LUNG-CANCER | PHASE-III TRIAL | SURVIVAL | PLACEBO | MITOXANTRONE | ONCOLOGY | RATE CONSTANTS | DOUBLE-BLIND | OPEN-LABEL | DOCETAXEL PLUS PREDNISONE | CHEMOTHERAPY | Prednisone - administration & dosage | Prognosis | Follow-Up Studies | Mitoxantrone - administration & dosage | Prostatic Neoplasms, Castration-Resistant - blood | Humans | Kaplan-Meier Estimate | Male | Survival Rate | Prostatic Neoplasms, Castration-Resistant - drug therapy | Case-Control Studies | Prostate-Specific Antigen - blood | Prostatic Neoplasms, Castration-Resistant - pathology | Randomized Controlled Trials as Topic | Biomarkers, Tumor - blood | Taxoids - administration & dosage | Clinical Trials, Phase III as Topic | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Retrospective Studies | Neoplasm Staging | Cancer patients | Care and treatment | Metastasis | Pharmaceutical industry | Growth | Prostate cancer | Analysis | Tumors
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3. Full Text Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
by Gakidou, Emmanuela and Afshin, Ashkan and Abajobir, Amanuel Alemu and Abate, Kalkidan Hassen and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abdulle, Abdishakur M and Abera, Semaw Ferede and Aboyans, Victor and Abu-Raddad, Laith J and Abu-Rmeileh, Niveen M E and Abyu, Gebre Yitayih and Adedeji, Isaac Akinkunmi and Adetokunboh, Olatunji and Afarideh, Mohsen and Agrawal, Sutapa and Agrawal, Anurag and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Amani Nidhal and Aichour, Miloud Taki Eddine and Aichour, Ibtihel and Akinyemi, Rufus Olusola and Akseer, Nadia and Alahdab, Fares and Al-Aly, Ziyad and Alam, Tahiya and Alam, Noore and Alam, Khurshid and Alasfoor, Deena and Alene, Kefyalew Addis and Ali, Komal and Alizadeh-Navaei, Reza and Alkerwi, Ala'a and Alla, François and Allebeck, Peter and Al-Raddadi, Rajaa and Alsharif, Ubai and Altirkawi, Khalid A and Alvis-Guzman, Nelson and Amare, Azmeraw T and Amini, Erfan and Ammar, Walid and Amoako, Yaw Ampem and Ansari, Hossein and Antó, Josep M and Antonio, Carl Abelardo T and Anwari, Palwasha and Arian, Nicholas and Ärnlöv, Johan and Artaman, Al and Aryal, Krishna Kumar and Asayesh, Hamid and Asgedom, Solomon Weldegebreal and Atey, Tesfay Mehari and Avila-Burgos, Leticia and Avokpaho, Euripide Frinel G Arthur and Awasthi, Ashish and Azzopardi, Peter and Bacha, Umar and Badawi, Alaa and Balakrishnan, Kalpana and Ballew, Shoshana H and Barac, Aleksandra and Barber, Ryan M and Barker-Collo, Suzanne L and Bärnighausen, Till and Barquera, Simon and Barregard, Lars and Barrero, Lope H and Batis, Carolina and Battle, Katherine E and Baumgarner, Blair R and Baune, Bernhard T and Beardsley, Justin and Bedi, Neeraj and Beghi, Ettore and Bell, Michelle L and Bennett, James R and Bennett, Derrick A and Bensenor, Isabela M and Berhane, Adugnaw and Berhe, Derbew Fikadu and Bernabé, Eduardo and Betsu, Balem Demtsu and Beuran, Mircea and Beyene, Addisu Shunu and Bhansali, Anil and Bhutta, Zulfiqar A and Bicer, Burcu Kucuk and Bikbov, Boris and Birungi, Charles and Biryukov, Stan and Blosser, Christopher D and Boneya, Dube Jara and Bou-Orm, Ibrahim R and Brauer, Michael and Breitborde, Nicholas J K and Brenner, Hermann and ... and GBD Risk Factors Collaborators and GBD 2016 Risk Factors Collaborators and Medicinska fakulteten and Klinisk kemi and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper
The Lancet, ISSN 0140-6736, 09/2017, Volume 390, Issue 10100, pp. 1345 - 1422
The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of risk factor exposure and attributable... 
MORTALITY | OBESITY PREVENTION | PRECAUTIONARY PRINCIPLE | COST | COUNTRIES | HEALTH-RISKS | DEATHS | HYPERTENSION | CHINESE POPULATION | EPIDEMIOLOGY | WOMEN | MEDICINE, GENERAL & INTERNAL | OBESITY | PREVENTION | TRENDS | Global Burden of Disease - statistics & numerical data | Humans | Middle Aged | Water Supply - standards | Child, Preschool | Infant | Male | Water Supply - statistics & numerical data | Young Adult | Occupational Diseases - mortality | Life Expectancy | Metabolic Diseases - mortality | Aged, 80 and over | Adult | Disabled Persons - statistics & numerical data | Female | Child | Communicable Diseases - mortality | Infant, Newborn | Body Mass Index | Quality-Adjusted Life Years | Air Pollution - statistics & numerical data | Smoking - mortality | Risk Assessment | Noncommunicable Diseases - mortality | Environmental Health - statistics & numerical data | Adolescent | Sex Distribution | Cause of Death - trends | Aged | Medicine, Experimental | Medical research | Comparative analysis | Risk assessment | Outdoor air quality | Disease | Premature birth | Mortality | Regional analysis | Alcohol | Metabolism | Ecological risk assessment | Disease prevention | Studies | Domestic violence | Tobacco | Diet | Blood pressure | Trends | Risk exposure | Health risk assessment | Injuries | Public health | Glucose | Gestation | Blood | Risk factors | Counting methods | Clusters | Aging | Population | Age | Environmental assessment | Fasting | Population growth | Health | Causation | Health risks | Exposure | Risk analysis | Charities | Air pollution | Fatalities | Birth weight | Kidney diseases | Indoor air pollution | Smoking | Samfunnsmedisin, sosialmedisin: 801 | Community medicine, Social medicine: 801 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Salut | Risk factors in diseases | Factors de risc en les malalties | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences | Nutrition and Disease | HNE Nutrition and Disease | Chair Nutrition and Disease | Voeding en Ziekte | VLAG | HNE Voeding en Ziekte
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4. Full Text Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
by Vos, Theo and Abajobir, Amanuel Alemu and Abate, Kalkidan Hassen and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abdulkader, Rizwan Suliankatchi and Abdulle, Abdishakur M and Abebo, Teshome Abuka and Abera, Semaw Ferede and Aboyans, Victor and Abu-Raddad, Laith J and Ackerman, Ilana N and Adamu, Abdu Abdullahi and Adetokunboh, Olatunji and Afarideh, Mohsen and Afshin, Ashkan and Agarwal, Sanjay Kumar and Aggarwal, Rakesh and Agrawal, Anurag and Agrawal, Sutapa and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Ibtihel and Aichour, Amani Nidhal and Aichour, Miloud Taki Eddine and Aiyar, Sneha and Akinyemi, Rufus Olusola and Akseer, Nadia and Al Lami, Faris Hasan and Alahdab, Fares and Al-Aly, Ziyad and Alam, Khurshid and Alam, Noore and Alam, Tahiya and Alasfoor, Deena and Alene, Kefyalew Addis and Ali, Raghib and Alizadeh-Navaei, Reza and Alkerwi, Ala'a and Alla, François and Allebeck, Peter and Allen, Christine and Al-Maskari, Fatma and Al-Raddadi, Rajaa and Alsharif, Ubai and Alsowaidi, Shirina and Altirkawi, Khalid A and Amare, Azmeraw T and Amini, Erfan and Ammar, Walid and Amoako, Yaw Ampem and Andersen, Hjalte H and Antonio, Carl Abelardo T and Anwari, Palwasha and Ärnlöv, Johan and Artaman, Al and Aryal, Krishna Kumar and Asayesh, Hamid and Asgedom, Solomon W and Assadi, Reza and Atey, Tesfay Mehari and Atnafu, Niguse Tadele and Atre, Sachin R and Avila-Burgos, Leticia and Avokphako, Euripide Frinel G Arthur and Awasthi, Ashish and Bacha, Umar and Badawi, Alaa and Balakrishnan, Kalpana and Banerjee, Amitava and Bannick, Marlena S and Barac, Aleksandra and Barber, Ryan M and Barker-Collo, Suzanne L and Bärnighausen, Till and Barquera, Simon and Barregard, Lars and Barrero, Lope H and Basu, Sanjay and Battista, Bob and Battle, Katherine E and Baune, Bernhard T and Bazargan-Hejazi, Shahrzad and Beardsley, Justin and Bedi, Neeraj and Beghi, Ettore and Béjot, Yannick and Bekele, Bayu Begashaw and Bell, Michelle L and Bennett, Derrick A and Bensenor, Isabela M and Benson, Jennifer and Berhane, Adugnaw and Berhe, Derbew Fikadu and Bernabé, Eduardo and Betsu, Balem Demtsu and Beuran, Mircea and Beyene, Addisu Shunu and Bhala, Neeraj and ... and GBD 2016 Dis Injury Incidence Prev and GBD 2016 Disease and Injury Incidence and Prevalence Collaborators and Institutionen för hälsovetenskaper and Örebro universitet
The Lancet, ISSN 0140-6736, 09/2017, Volume 390, Issue 10100, pp. 1211 - 1259
As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the... 
MORTALITY | DEPRESSION | CHRONIC PAIN | CLIMATE-CHANGE | DISORDERS | FUTURE | PERSONAL HEALTH-CARE | TRENDS | MEDICINE, GENERAL & INTERNAL | Medicine, Experimental | Medical research | Mental disorders | Disease | Personal health | Mortality | Mental health | Disease control | Risk factors | Studies | Disability | Aging | Age | Public health | Injury analysis | Injuries | Chronic illnesses | Guillain-Barre syndrome | Low back pain | Gout | Disorders | Mental depression | Tropical diseases | Incidence | Ratios | Fertility | Anxiety | Alzheimer's disease | Life expectancy | Population growth | Nutrient deficiency | Neurodegenerative diseases | Violence | Anemia | Regression analysis | Firearms | Self destructive behavior | Hearing loss | Diseases | Charities | Substance use | Hospitals | Tuberculosis | Adults | Cardiovascular diseases | Bayesian analysis | Headache | Populations | Iron | Sexual assault | Demographics | Pain | Remission | Children | Heart diseases | Complications | Aggression | Migraine | Diabetes mellitus | Health risks | Estimates | Life span | Community medicine, Social medicine: 801 | Samfunnsmedisin, sosialmedisin: 801 | Epidemiology medical and dental statistics: 803 | Epidemiologi medisinsk og odontologisk statistikk: 803 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Global Health Metrics | Clinical Medicine | Allmänmedicin | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | General Practice
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