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Nature communications, ISSN 2041-1723, 11/2018, Volume 9, Issue 1, pp. 4831 - 11
Much of the mammalian skeleton originates from a cartilage template eventually replaced by bone via endochondral ossification. Despite much knowledge about... 
CHONDROCYTE HYPERTROPHY | ENDOCHONDRAL BONE-GROWTH | MULTIDISCIPLINARY SCIENCES | AEROBIC GLYCOLYSIS | OSTEOBLASTS | INDIAN-HEDGEHOG | DIFFERENTIATION | SMAD | EXPRESSION | CHONDROGENESIS | CARTILAGE | Bone Morphogenetic Protein 1 - deficiency | Bone Morphogenetic Protein 2 - pharmacology | Chondrocytes - cytology | Chondrogenesis - genetics | Embryo, Mammalian | Male | Chondrocytes - drug effects | Bone Morphogenetic Protein 1 - genetics | Mechanistic Target of Rapamycin Complex 1 - genetics | Gene Expression Regulation, Developmental | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Bone Morphogenetic Protein 2 - metabolism | Bone Morphogenetic Protein Receptors, Type I - deficiency | Bone and Bones - metabolism | Cartilage - cytology | Female | Osteoblasts - cytology | Chondrocytes - metabolism | Osteogenesis - genetics | Bone and Bones - cytology | Animals, Newborn | Bone Morphogenetic Protein 2 - genetics | Cartilage - growth & development | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Osteoblasts - drug effects | Bone Morphogenetic Protein Receptors, Type I - genetics | Signal Transduction - genetics | Cartilage - metabolism | Mechanistic Target of Rapamycin Complex 1 - metabolism | Mice, Knockout | Animals | Glucose Transporter Type 1 - deficiency | Glucose Transporter Type 1 - genetics | Cell Differentiation - drug effects | Glucose - metabolism | Cell Proliferation - drug effects | Mice | Primary Cell Culture | Osteoblasts - metabolism | Glucose transporter | Bone morphogenetic protein 2 | mRNA | Glucose | Metabolism | Protein turnover | Ossification | Proteins | Cartilage | Glucose metabolism | Signaling | Clonal deletion | Chondrocytes | Deletion | Skeleton | Chondrogenesis | Growth factors | Transporter | Bone (endochondral) | Hypertrophy | Recombinant
Journal Article
Circulation Research, ISSN 0009-7330, 07/2018, Volume 123, Issue 3, pp. 329 - 331
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 09/2016, Volume 57, Issue 9, pp. 1619 - 1635
Journal Article
by Chen, H and Ji, X and Lee, WC and Shi, Y and Li, BE and Abel, ED and Jiang, DM and Huang, W and Long, FX
FASEB JOURNAL, ISSN 0892-6638, 07/2019, Volume 33, Issue 7, pp. 7810 - 7821
Wingless/integrated (Wnt) signaling has emerged as a major mechanism for promoting bone formation and a target pathway for developing bone anabolic agents... 
glucose | ACTIVATION | WNT1 MUTATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | osteoblast | BETA-CATENIN | DELETION | CELL BIOLOGY | mouse | METABOLISM | SOST GENE | ANABOLISM | Glut1 | AEROBIC GLYCOLYSIS | BIOLOGY | Slc2a1 | DIFFERENTIATION
Journal Article
Obesity, ISSN 1930-7381, 05/2019, Volume 27, Issue 5, pp. 793 - 802
Objective Multiplexed metabolic phenotyping systems are available from multiple commercial vendors, and each system includes unique design features. Although... 
NUTRITION & DIETETICS | RESPIROMETRY | TEMPERATURE | GLUCOSE | CALORIMETRY | ENDOCRINOLOGY & METABOLISM | EXPENDITURE | C57BL/6 | BALANCE | Calorimetry | Energy | Metabolism | Promethion | OxyMax
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 1984
Journal Article
Circulation, ISSN 0009-7322, 06/2007, Volume 115, Issue 25, pp. 3213 - 3223
Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease, and many believe that diabetes leads to... 
Heart failure | Obesity | Metabolism | Fatty acids | Diabetes mellitus | heart failure | CARDIAC & CARDIOVASCULAR SYSTEMS | fatty acids | OBESE ZUCKER RATS | BB WOR RAT | CONTRACTILE DYSFUNCTION | diabetes mellitus | ACTIVATED RECEPTOR-ALPHA | REDUCED CARDIAC EFFICIENCY | LEFT-VENTRICULAR STRUCTURE | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | PERIPHERAL VASCULAR DISEASE | metabolism | CONGESTIVE-HEART-FAILURE | obesity | CORONARY-ARTERY-DISEASE | Diastole | Oxidative Stress | Calcium - metabolism | Humans | Heart Failure - physiopathology | Homeostasis | Cardiomyopathies - prevention & control | Cardiomyopathies - etiology | Heart Failure - prevention & control | Fatty Acids, Nonesterified - metabolism | Cardiomyopathies - physiopathology | Mice, Mutant Strains | Diabetes Complications - epidemiology | Models, Animal | Diabetes Mellitus, Experimental - complications | Heart Failure - epidemiology | Heart Failure - etiology | Diabetes Complications - prevention & control | Diabetes Mellitus, Experimental - physiopathology | Diabetes Complications - physiopathology | Rats | Ventricular Dysfunction, Left - etiology | Renin-Angiotensin System - physiology | Ventricular Dysfunction, Left - physiopathology | Rats, Zucker | Cardiomyopathies - epidemiology | Animals | Mitochondria, Heart - physiology | Mice | PPAR alpha - metabolism | Development and progression | Diabetes | Cardiomyopathy | Heart diseases | Risk factors
Journal Article
Journal Article
Circulation research, 01/2019, Volume 124, Issue 1, pp. 121 - 141
Patients with diabetes mellitus have >2× the risk for developing heart failure (HF; HF with reduced ejection fraction and HF with preserved ejection fraction).... 
heart failure | hyperglycemia | diabetes mellitus | diabetic cardiomyopathy | prognosis
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A17659 - A17659
Glucose and lactate are important fuel substrates for the heart, particularly during acute hemodynamic stresses such as pressure overload or following exercise... 
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue 19
Journal Article