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Journal Article
Cancer Research, ISSN 0008-5472, 12/2016, Volume 76, Issue 24 Supplement, pp. A62 - A62
Journal Article
Cancer Research, ISSN 0008-5472, 07/2015, Volume 75, Issue 13 Supplement, pp. A65 - A65
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 7, pp. 2891 - 2900
The forkhead box transcription factor, FOXD3, is a stemness factor that prevents the production of melanocyte progenitors from the developing neural crest;... 
p21Cip1 | FOXD3 | melanoma | B-RAF | p53
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 3928 - 3928
Journal Article
Oncogene, ISSN 0950-9232, 5/2012, Volume 31, Issue 19, pp. 2471 - 2479
Melanoma cells driven by mutant B-RAF are highly resistant to chemotherapeutic treatments. Recent Phase 1 results with PLX4032/RG7204/Vemurafenib, which... 
FOXD3 | RAF inhibitor | ERK1 | chemotherapeutic resistance
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 4838 - 4838
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e91983 - e91983
Background: Pancreatic cancer stem cells (CSCs) represent a small subpopulation of pancreatic cancer cells that have the capacity to initiate and propagate... 
BREAST-CANCER | TUMOR | DIFFERENTIATION | CLEAVAGE | PROSPECTIVE IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | Transcription Factor HES-1 | Pancreatic Neoplasms - metabolism | Neoplastic Stem Cells - drug effects | Receptors, Notch - metabolism | Homeodomain Proteins - metabolism | Humans | Spheroids, Cellular - pathology | Gene Expression Profiling | Protease Inhibitors - pharmacology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Spheroids, Cellular - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Disease Models, Animal | Basic Helix-Loop-Helix Transcription Factors - genetics | Pancreatic Neoplasms - pathology | Spheroids, Cellular - metabolism | Pancreatic Neoplasms - genetics | Mice, SCID | Homeodomain Proteins - genetics | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | Ligands | Mice, Inbred NOD | RNA, Small Interfering - metabolism | Stem cells | Brain cancer | Stem cell transplantation | Metastasis | Cancer therapies | Signal transduction | Receptors | Cell growth | Allografts | Consent | Surgery | Xenografts | Tumorigenesis | Medical research | Departments | Review boards | Breast cancer | Gene expression | Signaling | Chemotherapy | Brain research | Inhibitors | Pancreatic cancer | Notch protein | Secretase | Tumors | Cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 1067 - 1067
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 4310 - 4310
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 2127 - 2127
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 7, pp. 2750 - 2760
This study addresses the role of PTEN loss in intrinsic resistance to the BRAF inhibitor PLX4720. Immunohistochemical staining of a tissue array covering all... 
METASTATIC MELANOMA | APOPTOSIS | PROTEIN | ONCOLOGY | PHOSPHORYLATION | CUTANEOUS MELANOMA | RAF KINASE | CANCER | MEDIATES RESISTANCE | LINES | ERK | RNA, Small Interfering - genetics | Up-Regulation | Humans | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - biosynthesis | Bcl-2-Like Protein 11 | Melanoma - genetics | Apoptosis Regulatory Proteins - genetics | Indoles - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Apoptosis Regulatory Proteins - biosynthesis | Melanoma - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | PTEN Phosphohydrolase - deficiency | Membrane Proteins - genetics | PTEN Phosphohydrolase - biosynthesis | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Membrane Proteins - biosynthesis | Membrane Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Mutation | RNA, Small Interfering - administration & dosage | Index Medicus | PTEN | melanoma | BRAF | PLX4032 | therapy | resistance
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 4807 - 4807
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2013, Volume 123, Issue 5, pp. 2155 - 2168
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 12/2012, Volume 72, Issue 24, pp. 6382 - 6392
Tumor cells often use developmental processes to progress toward advanced disease. The E-box transcription factor TWIST1 is essential to epithelial-mesenchymal... 
RNA INTERFERENCE | TARGET GENES | ONCOLOGY | MATRIX METALLOPROTEINASE-1 | BRAF MUTATION | TUMOR-METASTASIS | GROWTH | EPITHELIAL-MESENCHYMAL TRANSITIONS | MELANOCYTIC NEVI | UP-REGULATION | CANCER | Gene Expression Regulation, Enzymologic - drug effects | MAP Kinase Signaling System - physiology | Humans | Spheroids, Cellular - pathology | Matrix Metalloproteinase 1 - physiology | Spheroids, Cellular - physiology | MAP Kinase Signaling System - genetics | Melanoma - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Nuclear Proteins - genetics | Matrix Metalloproteinase 1 - genetics | Proto-Oncogene Proteins B-raf - metabolism | Melanoma - metabolism | Skin Neoplasms - pathology | Mitogen-Activated Protein Kinase 3 - genetics | Twist-Related Protein 1 - antagonists & inhibitors | Neoplasm Invasiveness | RNA, Small Interfering - pharmacology | Spheroids, Cellular - metabolism | Nuclear Proteins - metabolism | Melanoma - pathology | Skin Neoplasms - metabolism | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Proto-Oncogene Proteins B-raf - genetics | Nuclear Proteins - antagonists & inhibitors | Skin Neoplasms - genetics | Twist-Related Protein 1 - physiology | Twist-Related Protein 1 - genetics | Cell Proliferation - drug effects | Nuclear Proteins - physiology | Matrix Metalloproteinase 1 - metabolism | Twist-Related Protein 1 - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | TWIST1 | melanoma | invasion | MMP-1 | ERK
Journal Article
Frontiers in Bioscience - Scholar, ISSN 1945-0516, 01/2011, Volume 3, Issue 3, pp. 937 - 945
Journal Article
Oncogene, ISSN 0950-9232, 03/2016, Volume 35, Issue 10, pp. 1225 - 1235
Journal Article
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