Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (50) 50
Publication (18) 18
Book / eBook (6) 6
Dissertation (4) 4
Book Chapter (2) 2
Book Review (2) 2
Conference Proceeding (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (29) 29
humans (24) 24
article (15) 15
animals (13) 13
cancer (11) 11
oncology (11) 11
cell biology (10) 10
cell line, tumor (10) 10
melanoma (9) 9
melanoma - metabolism (9) 9
melanoma - pathology (9) 9
mice (9) 9
gene expression (8) 8
proto-oncogene proteins b-raf - metabolism (8) 8
phosphorylation (7) 7
signal transduction (7) 7
braf (6) 6
genetic aspects (6) 6
pancreatic neoplasms - pathology (6) 6
proto-oncogene proteins b-raf - genetics (6) 6
stem cells (6) 6
b-raf (5) 5
disease models, animal (5) 5
female (5) 5
gene expression regulation, neoplastic (5) 5
metastasis (5) 5
neoplasm invasiveness (5) 5
neoplastic stem cells - metabolism (5) 5
activation (4) 4
biochemistry & molecular biology (4) 4
cyclin d1 (4) 4
ductal adenocarcinoma (4) 4
expression (4) 4
gene knockdown techniques (4) 4
genes (4) 4
genetics & heredity (4) 4
growth (4) 4
male (4) 4
melanoma - genetics (4) 4
melanoma-cells (4) 4
mice, transgenic (4) 4
mutation (4) 4
pancreatic cancer (4) 4
rna, small interfering - genetics (4) 4
signal transduction - drug effects (4) 4
skin neoplasms - metabolism (4) 4
tumor (4) 4
tumor cells, cultured (4) 4
tumors (4) 4
up-regulation (4) 4
animal structures (3) 3
apoptosis (3) 3
biomarkers (3) 3
bladder cancer (3) 3
epithelial-mesenchymal transition (3) 3
extracellular signal-regulated map kinases - metabolism (3) 3
forkhead transcription factors - metabolism (3) 3
gene expression regulation, neoplastic - drug effects (3) 3
history and criticism (3) 3
indoles - pharmacology (3) 3
invasion (3) 3
map kinase signaling system - genetics (3) 3
metabolism (3) 3
mitogen-activated protein kinase kinases - metabolism (3) 3
multidisciplinary sciences (3) 3
neoplastic stem cells - pathology (3) 3
pancreatic neoplasms - genetics (3) 3
pancreatic neoplasms - metabolism (3) 3
physiological aspects (3) 3
progression (3) 3
protein (3) 3
proto-oncogene proteins b-raf - antagonists & inhibitors (3) 3
proto-oncogene proteins p21 - genetics (3) 3
proto-oncogene proteins p21 - metabolism (3) 3
research (3) 3
risk (3) 3
signaling pathway (3) 3
skin neoplasms - pathology (3) 3
sulfonamides - pharmacology (3) 3
transcription factors - metabolism (3) 3
tuberculosis (3) 3
xenograft model antitumor assays (3) 3
abridged index medicus (2) 2
actin depolymerizing factors - metabolism (2) 2
actins - metabolism (2) 2
activated protein-kinase (2) 2
adenocarcinoma - pathology (2) 2
aged (2) 2
analysis (2) 2
antigens, cd - metabolism (2) 2
articles (2) 2
beta catenin - metabolism (2) 2
biomarkers, tumor - metabolism (2) 2
breast-cancer (2) 2
carcinoma, pancreatic ductal - pathology (2) 2
carcinoma, pancreatic ductal - physiopathology (2) 2
care and treatment (2) 2
cell communication (2) 2
cell differentiation (2) 2
cell proliferation (2) 2
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
UTL at Downsview - May be requested (3) 3
Robarts - Stacks (2) 2
Gerstein Science - Stacks (1) 1
Music - Stacks (1) 1
Online Resources - Online (1) 1
Trinity College (John W Graham) - Stacks (1) 1
UofT at Mississauga - Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
Victoria University E.J. Pratt - Stacks (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text FOXD3 Is a Mutant B-RAF-Regulated Inhibitor of G(1)-S Progression in Melanoma Cells
by Abel, EV and Aplin, AE
CANCER RESEARCH, ISSN 0008-5472, 04/2010, Volume 70, Issue 7, pp. 2891 - 2900
The forkhead box transcription factor FOXD3 is a stemness factor that prevents the production of melanocyte progenitors from the developing neural crest;... 
PIGMENT-CELLS | ONCOLOGY | CYCLIN D1 | BRAF MUTATIONS | KINASE | SELF-RENEWAL | MALIGNANT-MELANOMA | NEURAL CREST | LINEAGE | CANCER | MOUSE EMBRYO | RNA, Small Interfering - genetics | Up-Regulation | Tumor Suppressor Protein p53 - biosynthesis | Humans | Gene Expression Regulation, Neoplastic | Cell Growth Processes - physiology | Tumor Suppressor Protein p53 - genetics | Gene Knockdown Techniques | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Transfection | Forkhead Transcription Factors - metabolism | Melanoma - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | MAP Kinase Kinase Kinases - antagonists & inhibitors | Cell Differentiation - physiology | Proto-Oncogene Proteins B-raf - metabolism | Melanoma - metabolism | Forkhead Transcription Factors - biosynthesis | Cyclin-Dependent Kinase Inhibitor p21 - biosynthesis | Down-Regulation | MAP Kinase Kinase Kinases - metabolism | Melanoma - pathology | Forkhead Transcription Factors - genetics | G1 Phase - physiology | Proto-Oncogene Proteins B-raf - genetics | Cell Line, Tumor | S Phase - physiology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Abstract A62: ATDC is required for KRAS-induced pancreatic tumorigenesis
by Wang, Lidong and Yang, Huibin and Abel, Ethan V and Palmbos, Phillip L and Halbrook, Christophe and Takeuchi, Kenneth and Shi, Jiaqi and Zhang, Yaqing and Urs, Sumithra and Waghray, Meghna and Magliano, Marina Pasca di and Rhim, Andrew D and Crawford, Howard C and Simeone, Diane M
Cancer Research, ISSN 0008-5472, 12/2016, Volume 76, Issue 24 Supplement, pp. A62 - A62
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Abstract A65: Pancreatic cancer stem cell function is regulated by HNF1A
by Abel, Ethan V and Goto, Masashi and Dziubinski, Michele L and Kumar, Chandan and Ramanathan, Nikita and Simeone, Diane M
Cancer Research, ISSN 0008-5472, 07/2015, Volume 75, Issue 13 Supplement, pp. A65 - A65
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text FOXD3 is a mutant B-RAF-regulated inhibitor of G1-S progression in melanoma cells
by Abel, Ethan V and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 7, pp. 2891 - 2900
The forkhead box transcription factor, FOXD3, is a stemness factor that prevents the production of melanocyte progenitors from the developing neural crest;... 
p21Cip1 | FOXD3 | melanoma | B-RAF | p53
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Abstract 3928:In vivoERK1/2 reporting demonstrates the association and timing of ERK1/2 pathway reactivation and acquired resistance to RAF inhibitors
by Basile, Kevin J and Abel, Ethan V and Dadpey, Neda and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 3928 - 3928
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Adaptive up-regulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells
by Basile, Kevin J and Abel, Ethan V and Aplin, Andrew E
Oncogene, ISSN 0950-9232, 5/2012, Volume 31, Issue 19, pp. 2471 - 2479
Melanoma cells driven by mutant B-RAF are highly resistant to chemotherapeutic treatments. Recent Phase 1 results with PLX4032/RG7204/Vemurafenib, which... 
FOXD3 | RAF inhibitor | ERK1 | chemotherapeutic resistance
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Abstract 4838: Upregulation of ERBB3/HER3 by FOXD3, an adaptive response promoting resistance to RAF/MEK-inhibitors
by Abel, Ethan V and Basile, Kevin J and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 4838 - 4838
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text The notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer
by Abel, Ethan V and Kim, Edward J and Wu, Jingjiang and Hynes, Mark and Bednar, Filip and Proctor, Erica and Wang, Lidong and Dziubinski, Michele L and Simeone, Diane M
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e91983 - e91983
Background: Pancreatic cancer stem cells (CSCs) represent a small subpopulation of pancreatic cancer cells that have the capacity to initiate and propagate... 
BREAST-CANCER | TUMOR | DIFFERENTIATION | CLEAVAGE | PROSPECTIVE IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | Transcription Factor HES-1 | Pancreatic Neoplasms - metabolism | Neoplastic Stem Cells - drug effects | Receptors, Notch - metabolism | Homeodomain Proteins - metabolism | Humans | Spheroids, Cellular - pathology | Gene Expression Profiling | Protease Inhibitors - pharmacology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Spheroids, Cellular - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Disease Models, Animal | Basic Helix-Loop-Helix Transcription Factors - genetics | Pancreatic Neoplasms - pathology | Spheroids, Cellular - metabolism | Pancreatic Neoplasms - genetics | Mice, SCID | Homeodomain Proteins - genetics | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | Ligands | Mice, Inbred NOD | RNA, Small Interfering - metabolism | Stem cells | Brain cancer | Stem cell transplantation | Metastasis | Cancer therapies | Signal transduction | Receptors | Cell growth | Allografts | Consent | Surgery | Xenografts | Tumorigenesis | Medical research | Departments | Review boards | Breast cancer | Gene expression | Signaling | Chemotherapy | Brain research | Inhibitors | Pancreatic cancer | Notch protein | Secretase | Tumors | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Abstract 1067: FOXD3 is a B-RAFV600E-regulated inhibitor of G1/S progression in melanoma cells
by Abel, Ethan V and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 1067 - 1067
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Abstract 4310: TWIST1, a B-RAF effector, promotes invasion and is a novel regulator of MMP-1 in human melanoma cells
by Weiss, Michele B and Abel, Ethan V and Mayberry, Melanie M and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 4310 - 4310
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Abstract 2127: The role of FOXD3 in resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells
by Basile, Kevin J and Abel, Ethan V and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 2127 - 2127
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression
by Paraiso, Kim H. T and Xiang, Yun and Rebecca, Vito W and Abel, Ethan V and Chen, Y. Ann and Munko, A. Cecilia and Wood, Elizabeth and Fedorenko, Inna V and Sondak, Vernon K and Anderson, Alexander R. A and Ribas, Antoni and Palma, Maurizia Dalla and Nathanson, Katherine L and Koomen, John M and Messina, Jane L and Smalley, Keiran S. M
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 7, pp. 2750 - 2760
This study addresses the role of PTEN loss in intrinsic resistance to the BRAF inhibitor PLX4720. Immunohistochemical staining of a tissue array covering all... 
METASTATIC MELANOMA | APOPTOSIS | PROTEIN | ONCOLOGY | PHOSPHORYLATION | CUTANEOUS MELANOMA | RAF KINASE | CANCER | MEDIATES RESISTANCE | LINES | ERK | RNA, Small Interfering - genetics | Up-Regulation | Humans | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - biosynthesis | Bcl-2-Like Protein 11 | Melanoma - genetics | Apoptosis Regulatory Proteins - genetics | Indoles - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Apoptosis Regulatory Proteins - biosynthesis | Melanoma - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | PTEN Phosphohydrolase - deficiency | Membrane Proteins - genetics | PTEN Phosphohydrolase - biosynthesis | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Membrane Proteins - biosynthesis | Membrane Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Mutation | RNA, Small Interfering - administration & dosage | Index Medicus | PTEN | melanoma | BRAF | PLX4032 | therapy | resistance
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Abstract 4807: FOXD3 regulates Rnd3 and invasion in mutant BRAF melanoma cells
by Katiyar, Pragati Dixit and Abel, Ethan V and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 4807 - 4807
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3
by Abel, Ethan V and Basile, Kevin J and Kugel III, Curtis H and Witkiewicz, Agnieszka K and Le, Kaitlyn and Amaravadi, Ravi K and Karakousis, Giorgos C and Xu, Xiaowei and Xu, Wei and Schuchter, Lynn M and Lee, Jason B and Ertel, Adam and Fortina, Paolo and Aplin, Andrew E
Journal of Clinical Investigation, ISSN 0021-9738, 05/2013, Volume 123, Issue 5, pp. 2155 - 2168
The mechanisms underlying adaptive resistance of melanoma to targeted therapies remain unclear. By combining ChIP sequencing with microarray-based gene... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | INDUCED ACTIVATION | G-S PROGRESSION | MEK INHIBITION | CYCLIN D1 | ACQUIRED-RESISTANCE | TYROSINE KINASE INHIBITOR | BRAF | B-RAF | CELL-DEATH | Immunohistochemistry | Melanoma - metabolism | Phosphorylation | Receptor, ErbB-3 - metabolism | Oligonucleotide Array Sequence Analysis | Signal Transduction | Cell Survival | raf Kinases - antagonists & inhibitors | Humans | Enzyme Inhibitors - pharmacology | Gene Expression Regulation, Neoplastic | MAP Kinase Kinase Kinases - metabolism | Sulfonamides - pharmacology | raf Kinases - metabolism | Skin Neoplasms - metabolism | Forkhead Transcription Factors - metabolism | Indoles - pharmacology | Transcription, Genetic | MAP Kinase Kinase Kinases - antagonists & inhibitors | Quinazolines - pharmacology | Care and treatment | Usage | Enzyme inhibitors | Analysis | Melanoma | Genetic aspects | Cellular signal transduction | Research | Gene expression | Statistical analysis | Genes | Genomics | Software | Mutation | RNA polymerase | Laboratory animals | Experiments | Patients | Skin cancer | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma
by Kim, Edward J and Sahai, Vaibhav and Abel, Ethan V and Griffith, Kent A and Greenson, Joel K and Takebe, Naoko and Khan, Gazala N and Blau, John L and Craig, Ronald and Balis, Ulysses G and Zalupski, Mark M and Simeone, Diane M
Clinical Cancer Research, ISSN 1078-0432, 12/2014, Volume 20, Issue 23, pp. 5937 - 5945
Purpose: The hedgehog (HH) signaling pathway is a key regulator in tumorigenesis of pancreatic adenocarcinoma and is upregulated in pancreatic adenocarcinoma... 
PHASE-III TRIAL | PLUS GEMCITABINE | SURVIVAL | 1ST-LINE TREATMENT | ONCOLOGY-GROUP | THERAPY | ONCOLOGY | DUCTAL ADENOCARCINOMA | STROMA | CANCER | Adenocarcinoma - pathology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Hedgehog Proteins - metabolism | Male | Pancreatic Neoplasms - drug therapy | Neoplasm Metastasis | Neoplastic Stem Cells - metabolism | Aged, 80 and over | Female | Pancreatic Neoplasms - mortality | Biomarkers - metabolism | Pyridines - administration & dosage | Deoxycytidine - administration & dosage | Pancreatic Neoplasms - pathology | Treatment Outcome | Adenocarcinoma - drug therapy | Anilides - administration & dosage | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Biopsy | Aged | Deoxycytidine - analogs & derivatives | Adenocarcinoma - mortality | Index Medicus | GDC-0449 | stem cells | hedgehog | SMO | PTCH1 | fibrosis | GLI1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells
by Weiss, Michele B and Abel, Ethan V and Mayberry, Melanie M and Basile, Kevin J and Berger, Adam C and Aplin, Andrew E
Cancer Research, ISSN 0008-5472, 12/2012, Volume 72, Issue 24, pp. 6382 - 6392
Tumor cells often use developmental processes to progress toward advanced disease. The E-box transcription factor TWIST1 is essential to epithelial-mesenchymal... 
RNA INTERFERENCE | TARGET GENES | ONCOLOGY | MATRIX METALLOPROTEINASE-1 | BRAF MUTATION | TUMOR-METASTASIS | GROWTH | EPITHELIAL-MESENCHYMAL TRANSITIONS | MELANOCYTIC NEVI | UP-REGULATION | CANCER | Gene Expression Regulation, Enzymologic - drug effects | MAP Kinase Signaling System - physiology | Humans | Spheroids, Cellular - pathology | Matrix Metalloproteinase 1 - physiology | Spheroids, Cellular - physiology | MAP Kinase Signaling System - genetics | Melanoma - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Nuclear Proteins - genetics | Matrix Metalloproteinase 1 - genetics | Proto-Oncogene Proteins B-raf - metabolism | Melanoma - metabolism | Skin Neoplasms - pathology | Mitogen-Activated Protein Kinase 3 - genetics | Twist-Related Protein 1 - antagonists & inhibitors | Neoplasm Invasiveness | RNA, Small Interfering - pharmacology | Spheroids, Cellular - metabolism | Nuclear Proteins - metabolism | Melanoma - pathology | Skin Neoplasms - metabolism | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Proto-Oncogene Proteins B-raf - genetics | Nuclear Proteins - antagonists & inhibitors | Skin Neoplasms - genetics | Twist-Related Protein 1 - physiology | Twist-Related Protein 1 - genetics | Cell Proliferation - drug effects | Nuclear Proteins - physiology | Matrix Metalloproteinase 1 - metabolism | Twist-Related Protein 1 - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | TWIST1 | melanoma | invasion | MMP-1 | ERK
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Finding the root of the problem: The quest to identify melanoma stem cells
by Abel, Ethan V and Aplin, Andrew E
Frontiers in Bioscience - Scholar, ISSN 1945-0516, 01/2011, Volume 3, Issue 3, pp. 937 - 945
Stem Cells | Tumor-Initiating Cells | Review | Melanoma | Melanoma Propagating Cells
Journal Article
Details down arrow
18. Full Text Mcl-1 Is Required for Melanoma Cell Resistance to Anoikis
by Karen Boisvert-Adamo and Whitney Longmate and Ethan V. Abel and Andrew E. Aplin
Molecular Cancer Research, ISSN 1541-7786, 04/2009, Volume 7, Issue 4, pp. 549 - 556
Melanoma is a particularly aggressive tumor type that exhibits a high level of resistance to apoptosis. The serine/threonine kinase B-RAF is mutated in 50% to... 
Mcl-1 | Melanoma | Apoptosis | APOPTOSIS | ONCOLOGY | BAX | B-RAF | MALIGNANT-MELANOMA | BH3 DOMAINS | BCL-2 FAMILY-MEMBERS | KINASE ACTIVATION | CANCER | BH3-ONLY PROTEINS | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | Melanoma - metabolism | Skin Neoplasms - pathology | Phosphorylation | Proto-Oncogene Proteins c-bcl-2 - physiology | Signal Transduction | Humans | RNA, Small Interfering - pharmacology | Melanocytes - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Melanoma - pathology | Fibronectins - metabolism | Skin Neoplasms - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | RNA Interference | Cell Adhesion - physiology | Myeloid Cell Leukemia Sequence 1 Protein | Skin Neoplasms - genetics | bcl-Associated Death Protein - metabolism | Anoikis | Tumor Cells, Cultured | bcl-X Protein - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
19. Full Text ATDC mediates a TP63-regulated basal cancer invasive program
by Palmbos, Phillip L and Wang, Yin and Bankhead III, Armand and Kelleher, Alan J and Wang, Lidong and Yang, Huibin and Ahmet, McKenzie L and Gumkowski, Erica R and Welling, Samuel D and Magnuson, Brian and Leflein, Jacob and Lorenzatti Hiles, Guadalupe and Abel, Ethan V and Dziubinski, Michele L and Urs, Sumithra and Day, Mark L and Ljungman, Mats E and Simeone, Diane M
Oncogene, ISSN 0950-9232, 2019, Volume 38, Issue 18, pp. 3340 - 3354
Basal subtype cancers are deadly malignancies but the molecular events driving tumor lethality are not completely understood. Ataxia-telangiectasia group D... 
MIGRATION | BLADDER-CANCER | ISOFORMS | COMPREHENSIVE MOLECULAR CHARACTERIZATION | SUBTYPES | PROGNOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLASSIFICATION | GENOME | CELL BIOLOGY | TAXONOMY | ONCOLOGY | TRIM29 | GENETICS & HEREDITY | Genetic aspects | Gene expression | Health aspects | Genes | Cancer | Transcription | Invasiveness | Ataxia telangiectasia | Ataxia | Lethality | Regulatory sequences | Bladder cancer | Tumors | Metastases | Index Medicus | basal cancer | ATDC | TP63
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
20. Full Text Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells
by Fedorenko, I.V and Abel, E.V and Koomen, J.M and Fang, B and Wood, E.R and Chen, Y.A and Fisher, K.J and Iyengar, S and Dahlman, K.B and Wargo, J.A and Flaherty, K.T and Sosman, J.A and Sondak, V.K and Messina, J.L and Gibney, G.T and Smalley, K.S.M
Oncogene, ISSN 0950-9232, 03/2016, Volume 35, Issue 10, pp. 1225 - 1235
The mechanisms by which some melanoma cells adapt to Serine/threonine-protein kinase B-Raf (BRAF) inhibitor therapy are incompletely understood. In the present... 
ACTIVATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | E-CADHERIN | DRUG-RESISTANCE | BRAF(V600E) | CELL BIOLOGY | ONCOLOGY | ADAPTIVE RESISTANCE | GROWTH | GENETICS & HEREDITY | RAF INHIBITORS | EXTRACELLULAR-MATRIX | B-RAF | Proto-Oncogene Proteins B-raf - deficiency | Cell Survival - drug effects | PTEN Phosphohydrolase - genetics | RNA, Small Interfering - genetics | PTEN Phosphohydrolase - deficiency | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Melanoma - pathology | Fibronectins - metabolism | Gene Knockdown Techniques | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Proteomics | Cell Line, Tumor | Female | Mice | Protein Kinase Inhibitors - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Integrin alpha5beta1 - metabolism | Gene mutations | Melanoma | Cellular signal transduction | Genetic aspects | Models | Gene expression | Health aspects | Proteins | Mutation | Cellular biology | Kinases | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.