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Journal of Photochemistry & Photobiology, C: Photochemistry Reviews, ISSN 1389-5567, 09/2019, Volume 40, pp. 1 - 20
The rapidly expanding field of photoswitchable biomolecules is a major frontier in scientific research and provides unparalleled opportunities for studying... 
Photoswitching | Secondary structure | Peptidomimetics | Peptide | Isomerization | Medicine, Experimental | Medical research | Azo compounds | Peptides
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1720 - 16
Nitric oxide (NO) is a key regulator of endothelial cell and vascular function. The direct measurement of NO is challenging due to its short half-life, and as... 
SYNTHASE | CELLS | PROTEIN CORONA | CELLULAR APPLICATIONS | MULTIDISCIPLINARY SCIENCES | FLUORESCENT-PROBES | MEDIA | STRESS | Hydrogen peroxide | Nitric oxide | Fluorescence | Acetylcholine | Sensors | Spectrophotometry | Endothelial cells | Freeze-thawing
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2019, Volume 29, Issue 3, pp. 396 - 399
A series of dipeptide aldehydes containing different -terminal heterocycles was prepared and assayed against α-chymotrypsin to ascertain the importance of the... 
Chymotrypsin | Heterocycles | Peptidic aldehydes | β-Strand | Protease inhibitors | Peptidomimetic | DESIGN | CHEMISTRY, MEDICINAL | CALPAIN | SPECIFICITY | RECOGNITION | CHEMISTRY, ORGANIC | CYSTEINE | ALDEHYDES | PEPTIDE | beta-Strand | SERINE | BIOLOGICAL EVALUATION
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 09/2018, Volume 51, Issue 9, pp. 2237 - 2246
Journal Article
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 06/2019
PCNA is an excellent inhibition target to shut down highly proliferative cells and thereby develop a broad spectrum cancer therapeutic. It interacts with a... 
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2019, Volume 29, Issue 3, p. 396
A series of dipeptide aldehydes containing different N-terminal heterocycles was prepared and assayed in vitro against [alpha]-chymotrypsin to ascertain the... 
Chymotrypsin | Pyridine | Protease inhibitors | Proteases | Hydrogen | Bonds | Amino acids | Furans | Thiophene | Aldehydes | Hydrogen bonding
Journal Article
Organic Letters, ISSN 1523-7060, 02/2005, Volume 7, Issue 4, pp. 609 - 611
1-Benzyl-4-methylimidazoles with a range of substituents at the 2-position are prepared from O-pentafluorobenzoylamidoximes on treatment with catalytic amounts... 
OXIMES | ANALOGS | PYRROLE DERIVATIVES | CHEMISTRY, ORGANIC | HECK REACTION | ANTAGONISTS | BOND | Oximes - chemistry | Cyclization | Models, Molecular | Palladium | Amino Acids - chemical synthesis | Catalysis | Imidazoles - chemical synthesis
Journal Article
CHEMISTRY-A EUROPEAN JOURNAL, ISSN 0947-6539, 07/2015, Volume 21, Issue 30, pp. 10703 - 10713
Here the synthesis and characterization of a new class of spiropyran-based protease inhibitor is reported that can be reversibly photoswitched between an... 
surface chemistry | SPECIFICITY | LIGHT | ESTERIFICATION | enzymes | photoswitching | CHEMISTRY, MULTIDISCIPLINARY | PROTEASES | spiropyran | FLUORESCENCE MODULATION | NANOPARTICLES | RECOGNIZE BETA-STRANDS | ALPHA-CHYMOTRYPSIN | SURFACE | peptidomimetics | BINDING | Chymotrypsin | Equipment and supplies | Chemical properties | Protease inhibitors | Proteases | Fiber optics
Journal Article
Tetrahedron, ISSN 0040-4020, 03/2018, Volume 74, Issue 12, pp. 1240 - 1244
A rationally designed, pyrene-spiropyran hybrid Ca sensor ( ) with enhanced fluorescence intensity compared to a standalone spiropyran analogue is presented.... 
Spiropyran | Calcium sensor | Merocyanine | Photoswitchable | Fluorescence enhancement | CELLS | DYES | BLUE | CHEMISTRY, ORGANIC | MICROSCOPY | AUTOFLUORESCENCE | PROBES | SPIROBENZOPYRANS | METAL-ION COMPLEXATION | DYADS
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 15967 - 8
Organic fluorescent probes are widely used to detect key biomolecules; however, they often lack the photostability required for extended intracellular imaging.... 
Hydrogen peroxide | Hydrogen | Fluorescent indicators | Biosensors | Macrophages | Stains | Photobleaching
Journal Article
Analytical Chemistry, ISSN 0003-2700, 08/2018, Volume 90, Issue 16, p. 10039
This study reports on the real-time binding assessment between heavy metal ions and blood proteins immobilized onto nanoporous anodic alumina photonic crystals... 
Binding | Plasma | Transferrin | Change detection | Toxicity | Photonic crystals | Serum albumin | Exposure | Real time | Heavy metals | Aluminum oxide | Blood plasma | Proteins | Organic chemistry | Monitoring systems | Affinity | Optical thickness | Monitoring | Mercury (metal) | Metal ions
Journal Article
ACS Applied Materials and Interfaces, ISSN 1944-8244, 12/2018, Volume 10, Issue 49, pp. 41866 - 41870
Many biological processes are driven by the interaction of a host with a guest molecule. We show such interactions can be modulated by carefully defining the... 
nanotechnology | molecular recognition | fluorescence spectroscopy | materials science | ion-molecule reactions | nanoscale environment | nanotethnology | FILM | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | ALUMINUM | CHEMISTRY | FABRICATION | HEALTH
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 360a - 360a
Journal Article
Chemistry (Weinheim an der Bergstrasse, Germany), ISSN 0947-6539, 01/2019, Volume 25, Issue 3, pp. 854 - 862
A new spiropyran-based stimuli-responsive delivery system is fabricated. It encapsulates and then releases an extraneous compound in response to elevated... 
Journal Article
Chemistry - A European Journal, ISSN 0947-6539, 04/2015, Volume 21, Issue 15, p. 5926
Understanding the electronic properties of single peptides is not only of fundamental importance, but it is also paramount to the realization of peptide-based... 
Electrochemistry | Density functionals | Electrochemical reactions | Chemical properties | Peptides | Triazoles
Journal Article
Chemistry - A European Journal, ISSN 0947-6539, 07/2015, Volume 21, Issue 30, pp. 10915 - 10915
Journal Article
09/2017, Volume 7, Issue 67, pp. 4237 - 42378
Understanding the electronic properties inherent to peptides is crucial for controlling charge transfer, and precursory to the design and fabrication of... 
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 41, pp. 9731 - 9735
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 08/2018, Volume 24, Issue 44, pp. 11234 - 11234
PCNA Space Odyssey: PCNA (the human sliding clamp) is depicted as a protein surface representation (colored in grey) in complex with the first p21‐derived... 
protein–protein interactions | X-ray diffraction | peptidomimetics | NMR spectroscopy | DNA
Journal Article
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