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1. Full Text Photocontrol of peptide secondary structure through non-azobenzene photoswitches
by Peddie, Victoria and Abell, Andrew D
Journal of Photochemistry & Photobiology, C: Photochemistry Reviews, ISSN 1389-5567, 09/2019, Volume 40, pp. 1 - 20
The rapidly expanding field of photoswitchable biomolecules is a major frontier in scientific research and provides unparalleled opportunities for studying... 
Photoswitching | Secondary structure | Peptidomimetics | Peptide | Isomerization | Medicine, Experimental | Medical research | Azo compounds | Peptides
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2. Full Text A Novel Ruthenium-based Molecular Sensor to Detect Endothelial Nitric Oxide
by Vidanapathirana, Achini K and Pullen, Benjamin J and Zhang, Run and Duong, MyNgan and Goyne, Jarrad M and Zhang, Xiaozhou and Bonder, Claudine S and Abell, Andrew D and Bursill, Christina A and Nicholls, Stephen J and Psaltis, Peter J
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1720 - 16
Nitric oxide (NO) is a key regulator of endothelial cell and vascular function. The direct measurement of NO is challenging due to its short half-life, and as... 
SYNTHASE | CELLS | PROTEIN CORONA | CELLULAR APPLICATIONS | MULTIDISCIPLINARY SCIENCES | FLUORESCENT-PROBES | MEDIA | STRESS | Hydrogen peroxide | Nitric oxide | Fluorescence | Acetylcholine | Sensors | Spectrophotometry | Endothelial cells | Freeze-thawing
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3. Full Text The role of N-terminal heterocycles in hydrogen bonding to α-chymotrypsin
by Schumann, Nicholas C and Bruning, John and Marshall, Andrew C and Abell, Andrew D
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2019, Volume 29, Issue 3, pp. 396 - 399
A series of dipeptide aldehydes containing different -terminal heterocycles was prepared and assayed against α-chymotrypsin to ascertain the importance of the... 
Chymotrypsin | Heterocycles | Peptidic aldehydes | β-Strand | Protease inhibitors | Peptidomimetic | DESIGN | CHEMISTRY, MEDICINAL | CALPAIN | SPECIFICITY | RECOGNITION | CHEMISTRY, ORGANIC | CYSTEINE | ALDEHYDES | PEPTIDE | beta-Strand | SERINE | BIOLOGICAL EVALUATION
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4. Full Text Peptides as Bio-Inspired Electronic Materials: An Electrochemical and First-Principles Perspective
by Yu, Jingxian and Horsley, John R and Abell, Andrew D
Accounts of Chemical Research, ISSN 0001-4842, 09/2018, Volume 51, Issue 9, pp. 2237 - 2246
CONSPECTUS: Molecular electronics is at the forefront of interdisciplinary research, offering a significant extension of the capabilities of conventional... 
CONDUCTANCE | TRANSPORT | INTERPLAY | HELICAL PEPTIDES | MECHANISTIC TRANSITION | BACKBONE RIGIDITY | SUPEREXCHANGE | TUNABLE MOLECULAR WIRES | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | QUANTUM INTERFERENCE | Protein Conformation, alpha-Helical | Electricity | Peptides - chemistry | Protein Conformation, beta-Strand | Electrochemical Techniques - methods | Electronics - methods | Kinetics | Electrons
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5. Full Text Targeting PCNA with peptide mimetics for therapeutic purposes
by Horsfall, Aimee J and Abell, Andrew D and Bruning, John
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 06/2019
PCNA is an excellent inhibition target to shut down highly proliferative cells and thereby develop a broad spectrum cancer therapeutic. It interacts with a... 
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6. Full Text The role of N-terminal heterocycles in hydrogen bonding to [alpha]-chymotrypsin
by Schumann, Nicholas C and Bruning, John and Marshall, Andrew C and Abell, Andrew D
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2019, Volume 29, Issue 3, p. 396
A series of dipeptide aldehydes containing different N-terminal heterocycles was prepared and assayed in vitro against [alpha]-chymotrypsin to ascertain the... 
Chymotrypsin | Pyridine | Protease inhibitors | Proteases | Hydrogen | Bonds | Amino acids | Furans | Thiophene | Aldehydes | Hydrogen bonding
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7. Full Text Synthesis of trisubstituted imidazoles by palladium-catalyzed cyclization of O-pentafluorobenzoylamidoximes: Application to amino acid mimetics with a C-terminal imidazole
by Zaman, Shazia and Mitsuru, Kitamura and Abell, Andrew D
Organic Letters, ISSN 1523-7060, 02/2005, Volume 7, Issue 4, pp. 609 - 611
1-Benzyl-4-methylimidazoles with a range of substituents at the 2-position are prepared from O-pentafluorobenzoylamidoximes on treatment with catalytic amounts... 
OXIMES | ANALOGS | PYRROLE DERIVATIVES | CHEMISTRY, ORGANIC | HECK REACTION | ANTAGONISTS | BOND | Oximes - chemistry | Cyclization | Models, Molecular | Palladium | Amino Acids - chemical synthesis | Catalysis | Imidazoles - chemical synthesis
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8. Full Text Photoregulation of -Chymotrypsin Activity by Spiropyran-Based Inhibitors in Solution and Attached to an Optical Fiber
by Zhang, XZ and Heng, S and Abell, AD
CHEMISTRY-A EUROPEAN JOURNAL, ISSN 0947-6539, 07/2015, Volume 21, Issue 30, pp. 10703 - 10713
Here the synthesis and characterization of a new class of spiropyran-based protease inhibitor is reported that can be reversibly photoswitched between an... 
surface chemistry | SPECIFICITY | LIGHT | ESTERIFICATION | enzymes | photoswitching | CHEMISTRY, MULTIDISCIPLINARY | PROTEASES | spiropyran | FLUORESCENCE MODULATION | NANOPARTICLES | RECOGNIZE BETA-STRANDS | ALPHA-CHYMOTRYPSIN | SURFACE | peptidomimetics | BINDING | Chymotrypsin | Equipment and supplies | Chemical properties | Protease inhibitors | Proteases | Fiber optics
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9. Full Text A spiropyran with enhanced fluorescence: A bright, photostable and red-emitting calcium sensor
by Sylvia, Georgina M and Heng, Sabrina and Bachhuka, Akash and Ebendorff-Heidepriem, Heike and Abell, Andrew D
Tetrahedron, ISSN 0040-4020, 03/2018, Volume 74, Issue 12, pp. 1240 - 1244
A rationally designed, pyrene-spiropyran hybrid Ca sensor ( ) with enhanced fluorescence intensity compared to a standalone spiropyran analogue is presented.... 
Spiropyran | Calcium sensor | Merocyanine | Photoswitchable | Fluorescence enhancement | CELLS | DYES | BLUE | CHEMISTRY, ORGANIC | MICROSCOPY | AUTOFLUORESCENCE | PROBES | SPIROBENZOPYRANS | METAL-ION COMPLEXATION | DYADS
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10. Full Text An organic fluorophore-nanodiamond hybrid sensor for photostable imaging and orthogonal, on-demand biosensing
by Purdey, Malcolm S and Capon, Patrick K and Pullen, Benjamin J and Reineck, Philipp and Schwarz, Nisha and Psaltis, Peter J and Nicholls, Stephen J and Gibson, Brant C and Abell, Andrew D
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 15967 - 8
Organic fluorescent probes are widely used to detect key biomolecules; however, they often lack the photostability required for extended intracellular imaging.... 
Hydrogen peroxide | Hydrogen | Fluorescent indicators | Biosensors | Macrophages | Stains | Photobleaching
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11. Real-Time Binding Monitoring between Human Blood Proteins and Heavy Metal Ions in Nanoporous Anodic Alumina Photonic Crystals
by Cheryl Suwen Law and Siew Yee Lim and Andrew D Abell and Abel Santos
Analytical Chemistry, ISSN 0003-2700, 08/2018, Volume 90, Issue 16, p. 10039
This study reports on the real-time binding assessment between heavy metal ions and blood proteins immobilized onto nanoporous anodic alumina photonic crystals... 
Binding | Plasma | Transferrin | Change detection | Toxicity | Photonic crystals | Serum albumin | Exposure | Real time | Heavy metals | Aluminum oxide | Blood plasma | Proteins | Organic chemistry | Monitoring systems | Affinity | Optical thickness | Monitoring | Mercury (metal) | Metal ions
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12. Full Text Control of Molecular Recognition via Modulation of the Nanoenvironment
by Kostecki, Roman and Heng, Sabrina and Mak, Adrian M and Ebendorff-Heidepriem, Heike and Monro, Tanya M and Abell, Andrew D
ACS Applied Materials and Interfaces, ISSN 1944-8244, 12/2018, Volume 10, Issue 49, pp. 41866 - 41870
Many biological processes are driven by the interaction of a host with a guest molecule. We show such interactions can be modulated by carefully defining the... 
nanotechnology | molecular recognition | fluorescence spectroscopy | materials science | ion-molecule reactions | nanoscale environment | nanotethnology | FILM | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | ALUMINUM | CHEMISTRY | FABRICATION | HEALTH
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13. Full Text Real-Time Imaging of Lithium ‘Hot-Spots’: An Analysis of Ion Conductance in Aquaporin-1 using Novel Photo-Switchable Sensor
by Pei, Jinxin V and Heng, Sabrina and De Ieso, Micheal and Sylvia, Georgina and Kourghi, Mohamad and Abell, Andrew D and Yool, Andrea J
Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 360a - 360a
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14. Full Text Spiropyran-Based Nanocarrier: A New Zn 2+ -Responsive Delivery System with Real-Time Intracellular Sensing Capabilities
by Heng, Sabrina and Zhang, Xiaozhou and Pei, Jinxin and Adwal, Alaknanda and Reineck, Philipp and Gibson, Brant C and Hutchinson, Mark R and Abell, Andrew D
Chemistry (Weinheim an der Bergstrasse, Germany), ISSN 0947-6539, 01/2019, Volume 25, Issue 3, pp. 854 - 862
A new spiropyran-based stimuli-responsive delivery system is fabricated. It encapsulates and then releases an extraneous compound in response to elevated... 
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15. Full Text The Correlation of Electrochemical Measurements and Molecular Junction Conductance Simulations in [beta]-Strand Peptides
by Horsley, John R and Yu, Jingxian and Abell, Andrew D
Chemistry - A European Journal, ISSN 0947-6539, 04/2015, Volume 21, Issue 15, p. 5926
Understanding the electronic properties of single peptides is not only of fundamental importance, but it is also paramount to the realization of peptide-based... 
Electrochemistry | Density functionals | Electrochemical reactions | Chemical properties | Peptides | Triazoles
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16. Full Text Inside Back Cover: Photoregulation of α-Chymotrypsin Activity by Spiropyran-Based Inhibitors in Solution and Attached to an Optical Fiber (Chem. Eur. J. 30/2015)
by Zhang, Xiaozhou and Heng, Sabrina and Abell, Andrew. D
Chemistry - A European Journal, ISSN 0947-6539, 07/2015, Volume 21, Issue 30, pp. 10915 - 10915
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17. Full Text A controllable mechanistic transition of charge transfer in helical peptides: from hopping to superexchange
by Yu, Jingxian and Horsley, John R and Abell, Andrew D
09/2017, Volume 7, Issue 67, pp. 4237 - 42378
Understanding the electronic properties inherent to peptides is crucial for controlling charge transfer, and precursory to the design and fabrication of... 
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18. Full Text The key position: Influence of staple location on constrained peptide conformation and binding
by Keeling, Kelly L and Cho, Okki and Scanlon, Denis B and Booker, Grant W and Abell, Andrew D and Wegener, Kate L
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 41, pp. 9731 - 9735
Constrained alpha-helical peptides are showing potential as biological probes and therapeutic agents that target protein-protein interactions. However, the... 
DESIGN | INTEGRIN ACTIVATION | ALPHA-HELIX | PROTEIN | ASSIGNMENT | CHEMISTRY, ORGANIC | SECONDARY STRUCTURE | TALIN | WATER | Amino Acid Sequence | Integrin beta3 - metabolism | Peptide Fragments - chemistry | Peptide Fragments - metabolism | Protein Structure, Secondary | Talin - chemistry | Proteolysis | Integrin beta3 - chemistry | Models, Molecular | Protein Binding | Talin - metabolism | Lactams - chemistry
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19. Full Text Front Cover: Rational Design of a 310‐Helical PIP‐Box Mimetic Targeting PCNA, the Human Sliding Clamp (Chem. Eur. J. 44/2018)
by Wegener, Kate L and McGrath, Amy E and Dixon, Nicholas E and Oakley, Aaron J and Scanlon, Denis B and Abell, Andrew D and Bruning, John B
Chemistry – A European Journal, ISSN 0947-6539, 08/2018, Volume 24, Issue 44, pp. 11234 - 11234
PCNA Space Odyssey: PCNA (the human sliding clamp) is depicted as a protein surface representation (colored in grey) in complex with the first p21‐derived... 
protein–protein interactions | X-ray diffraction | peptidomimetics | NMR spectroscopy | DNA
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20. Inside Back Cover: Photoregulation of [alpha]-Chymotrypsin Activity by Spiropyran-Based Inhibitors in Solution and Attached to an Optical Fiber
by Xiaozhou Zhang and Sabrina Heng and Andrew D Abell
Chemistry, ISSN 0947-6539, 07/2015, Volume 21, Issue 30, p. 10915
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