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Journal of Heterocyclic Chemistry, ISSN 0022-152X, 04/2018, Volume 55, Issue 4, pp. i - i
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 04/2018, Volume 55, Issue 4, p. i
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 04/2018, Volume 55, Issue 4, pp. 803 - 813
Series of novel pyrazolo[3,4‐ d ]pyrimidines as potential telomerase inhibitors were synthesized. Results of the antitumor assay indicated that compounds 4b ,... 
CHEMISTRY, ORGANIC | CELLS | DESIGN | ANTICANCER | DERIVATIVES | Telomerase | Pyrimidines | Resveratrol | Inhibitors | Docking | Amino acids | Inhibition | Chemical synthesis | Cancer
Journal Article
ISSN 1477-0520, 4/2015, Volume 13, Issue 18, pp. 5115 - 5121
G-rich anti-parallel DNA triplexes were modified with LNA or α- l -LNA in their Watson-Crick and TFO strands. The triplexes were formed by targeting a... 
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 05/2015, Volume 13, Issue 18, pp. 5115 - 5121
G-rich anti-parallel DNA triplexes were modified with LNA or alpha-L-LNA in their Watson-Crick and TFO strands. The triplexes were formed by targeting a... 
SELF-ASSOCIATION | HELIX-FORMING OLIGODEOXYRIBONUCLEOTIDES | 2'-DEOXY-9-DEAZAGUANOSINE | POTASSIUM-MEDIATED INHIBITION | RNA | QUADRUPLEX DNA | LOCKED NUCLEIC-ACID | CHEMISTRY, ORGANIC | MOTIF | DUPLEX DNA | OLIGONUCLEOTIDES | Models, Molecular | Oligonucleotides - chemistry | DNA - chemistry | Temperature | Circular Dichroism | Index Medicus
Journal Article
Synthesis, ISSN 0039-7881, 12/2013, Volume 45, Issue 23, pp. 3259 - 3262
Abstract An allopurinol locked nucleic acid (LNA) monomer was prepared by a novel strategy through C6 deamination of the corresponding... 
paper | regioselectivity | nucleosides | nucleobases | glycosylations | DUPLEX STABILITY | ADENOSINE-DEAMINASE | NUCLEOSIDE ANALOGS | RNA | 2'-DEOXYRIBOFURANOSIDES | COVALENT HYDRATION | CHEMISTRY, ORGANIC | OLIGONUCLEOTIDES | DNA | RIBONUCLEOSIDES | LNA
Journal Article
Saudi Pharmaceutical Journal, ISSN 1319-0164, 07/2014, Volume 22, Issue 3, pp. 264 - 272
The cross talk between the over expression of oxygen-free radicals is known as reactive oxygen species (ROS) that is associated with the excessive telomerase... 
Design | Docking | Telomerase binding site | Synthesis | Antioxidant | Oxidative DNA damage | MECHANISM | TELOMERASE | CATALYTIC SUBUNIT TERT | DNA-DAMAGE | BIBR1532 | METALS | GROWTH | PHARMACOLOGY & PHARMACY | Original
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 410 - 421
A new series of 2-substituted mercapto-4(3 )-quinazolinone were synthesized and assessed for anti-inflammatory and analgesic activities and inhibition of... 
Docking study | Synthesis | 2-Mercapto-4(3H)-quinazolinone | Cyclooxygenase-1/cyclooxygenase-2 inhibition assay | Anti-inflammatory activities | inhibition assay | Cyclooxygenase-1/cyclooxygenase-2 | SELECTIVE-INHIBITION | DESIGN | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | ANALOGS | ANTITUMOR-ACTIVITY | DRUGS | BIOLOGICAL EVALUATION | DERIVATIVES | PROSTAGLANDIN SYNTHESIS | QUINAZOLINES | Analgesics - pharmacology | Analgesics - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Cyclooxygenase 2 Inhibitors - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Analgesics - chemical synthesis | Cyclooxygenase 1 - chemistry | Cyclooxygenase 2 Inhibitors - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Quinazolinones - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Chemistry Techniques, Synthetic | Cyclooxygenase 2 Inhibitors - pharmacology | Cyclooxygenase 2 - chemistry | Quinazolinones - chemical synthesis | Animals | Analgesics - chemistry | Cyclooxygenase 2 - metabolism | Protein Conformation | Mice | Molecular Docking Simulation | Quinazolinones - chemistry | Cyclooxygenase 1 - metabolism | Quinazolinones - metabolism | Drugstores | COX-2 inhibitors | Pharmacy | Diclofenac | Index Medicus
Journal Article
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 06/2016, Volume 115, pp. 121 - 131
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2010, Volume 18, Issue 8, pp. 2849 - 2863
Journal Article
Journal Article
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