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NATURE COMMUNICATIONS, ISSN 2041-1723, 01/2016, Volume 7, Issue 1, p. 8770
Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias,... 
CONDUCTANCE | PERMEABILITY | DOCKING | MULTIDISCIPLINARY SCIENCES | ALGORITHM | DISEASE | DYNAMICS | MOLECULAR DETERMINANTS | CONNEXIN CHANNELS | CHARMM | SELECTIVITY | Occlusion | Conduction | Intercellular signalling | Calcium | Homeostasis | Tissues | Electrostatic properties | Trauma | Channels | Interfaces | Nerve conduction | Molecular conformation | Computer applications | Chelation | Cations | Calcium ions | Crystal structure | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e42120
Journal Article
Current Computer-Aided Drug Design, ISSN 1573-4099, 2011, Volume 7, Issue 1, pp. 10 - 22
Journal Article
Journal of Clinical and Diagnostic Research, ISSN 2249-782X, 04/2018, Volume 12, Issue 4, pp. OC10 - OC14
Journal Article
Nature communications, ISSN 2041-1723, 01/2016, Volume 7, Issue 2016, p. 8770
Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias,... 
Protein Structure, Tertiary | Calcium - metabolism | Humans | Crystallization | Crystallography, X-Ray | Static Electricity | Molecular Dynamics Simulation | Connexins - metabolism | Spodoptera | Connexin 26 | Sf9 Cells | Animals | Synchrotrons | Connexins - chemistry
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 7/2009, Volume 26, Issue 7, pp. 1665 - 1678
Synthesize aminopiperidine conjugates of glutamyl-bile acids (glu-BAs) and develop a hASBT inhibition model using the conformationally sampled pharmacophore... 
Biomedical Engineering | Biochemistry, general | conformationally sampled pharmacophore | apical sodium-dependent bile acid transporter | Biomedicine | bile acid | Pharmacy | transporter | Medical Law | Pharmacology/Toxicology | CHARMM | Apical sodium-dependent bile acid transporter | Conformationally sampled pharmacophore | Transporter | Bile acid | MOLECULAR-DYNAMICS | ILEAL | MODEL | CHEMISTRY, MULTIDISCIPLINARY | BETA | INTESTINAL-ABSORPTION | PLASMA-CHOLESTEROL | EXPLOITATION | DELTA-OPIOID LIGANDS | PHARMACOLOGY & PHARMACY | EXPRESSION | Cell Line | Piperidines - chemistry | Piperidines - metabolism | Humans | Molecular Conformation | Organic Anion Transporters, Sodium-Dependent - antagonists & inhibitors | Bile Acids and Salts - chemistry | Models, Molecular | Bile Acids and Salts - metabolism | Kidney - cytology | Structure-Activity Relationship | Piperidines - chemical synthesis | Symporters - metabolism | Kidney - metabolism | Animals | Glutamic Acid - chemical synthesis | Computer Simulation | Symporters - antagonists & inhibitors | Dogs | Bile Acids and Salts - chemical synthesis | Glutamic Acid - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | Glutamic Acid - chemistry | Amino acids | Glutamate | Heterocyclic compounds | Analysis | Deoxycholic acid | Cellular biology | Pharmaceutical sciences | Binding sites | Bile | Apical Sodium-dependent Bile acid Transporter
Journal Article
Aaps Journal, ISSN 1550-7416, 2016, Volume 18, Issue 1, pp. 171 - 179
Journal Article
The AAPS Journal, ISSN 1550-7416, 9/2018, Volume 20, Issue 5, pp. 1 - 14
Journal Article
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 11/2010, Volume 21, Issue 11, p. 2038
The human apical sodium-dependent bile acid transporter (ASBT) is a validated drug target and can be employed to increase oral bioavailability of various drug... 
Proteins | Inhibitor drugs | Kinetics | Chemical synthesis | Chemical compounds | Cells | Binding sites
Journal Article
Helvetica chimica acta, ISSN 0018-019X, 2/2010, Volume 93, Issue 2, pp. 220 - 226
The Diels – Alder reaction was applied to 4,5-epoxymorphinan opioids to generate a novel aromatic cycloadduct at C(7) – C(8): Thermolytic cleavage of sultine 8... 
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 02/2010, Volume 93, Issue 2, pp. 220 - 226
Journal Article
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