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Immunity, ISSN 1074-7613, 06/2019, Volume 50, Issue 6, pp. 1344 - 1346
In this issue of Immunity, and show that lymphatic endothelial cells are essential components of the niche that forms and maintains the subcapsular sinusoidal... 
MACROPHAGES | IMMUNOLOGY | Pathogens | Genotype & phenotype | Lymphatic system | Sinuses | Homeostasis | Bone marrow | Infections | Macrophages | Immunity | Niches | Endothelial cells | Immune system
Journal Article
Journal Article
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, ISSN 0962-8436, 08/2019, Volume 374, Issue 1779, p. 20180214
The great ambition to treat cancer through harnessing a patient's own immune responses has started to become reality. Clinical trials have shown impressive... 
CELLS | COLLAGEN | PHASE-II | HYALURONAN | PROLIFERATION | fibroblast | immunotherapy | GROWTH | BIOLOGY | EXTRACELLULAR-MATRIX | DRAINING LYMPH-NODE | EXPRESSION | extracellular matrix | TUMOR MICROENVIRONMENT
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2012, Volume 3, p. 283
Podoplanin (PDPN) is a well-conserved, mucin-type transmembrane protein expressed in multiple tissues during ontogeny and in adult animals, including the... 
CLEC-2 | Cancer-associated fibroblasts | Lymphatic endothelial cells | Platelets | Lymph node stromal cells | Podoplanin | cancer-associated fibroblasts | lymphatic endothelial cells | IMMUNOLOGY | podoplanin | platelets | lymph node stromal cells | Clec-2
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2011, Volume 12, Issue 11, pp. 1096 - 1104
Journal Article
Nature, ISSN 0028-0836, 10/2014, Volume 514, Issue 7253, pp. 498 - 502
Journal Article
Immunity, ISSN 1074-7613, 08/2012, Volume 37, Issue 2, pp. 276 - 289
To initiate adaptive immunity, dendritic cells (DCs) move from parenchymal tissues to lymphoid organs by migrating along stromal scaffolds that display the... 
MIGRATION | LYMPHATIC VESSELS | INVASION | GTPASES | RAC | ROLES | IN-VIVO | RHO | NEUTROPHILS | IMMUNOLOGY | SECONDARY LYMPHOID ORGANS | Skin - cytology | Membrane Glycoproteins - metabolism | Embryo, Mammalian | Skin - metabolism | Dendritic Cells - immunology | Humans | Actins - metabolism | Lectins, C-Type - immunology | rhoA GTP-Binding Protein - metabolism | Lectins, C-Type - genetics | Cell Movement - physiology | Lectins, C-Type - metabolism | Flow Cytometry | Female | Endothelium, Lymphatic - metabolism | Dendritic Cells - metabolism | Green Fluorescent Proteins - metabolism | Adaptive Immunity - physiology | Antigen-Presenting Cells - metabolism | Endothelial Cells - metabolism | Tissue Culture Techniques | Mice, Inbred C57BL | Cells, Cultured | Lymph Nodes - metabolism | Lymph Nodes - cytology | Mice, Knockout | Pregnancy | Microscopy, Confocal | Animals | Blood Platelets - metabolism | Platelet Activation | Endothelium, Lymphatic - cytology | Signal Transduction - physiology | Mice | Myosin Light Chains - metabolism | Proto-Oncogene Proteins c-vav - metabolism | rac1 GTP-Binding Protein - metabolism | Medical colleges | Nervous system diseases | Dendritic cells | Actin | Developmental biology | Myosin | Lectins | Muscle proteins | T cells | Endothelium | Telecommunications services industry | Communications industry | Scholarships & fellowships | Phosphorylation | Statistical analysis | Motility | Blood platelets | Microscopy | Migration | Chemokines
Journal Article
ELIFE, ISSN 2050-084X, 09/2019, Volume 8
The challenges facing a new independent group leader, principal investigator (PI) or university lecturer are formidable: secure funding, recruit staff and... 
BIOLOGY | Variables | Leadership | Ethnicity | Researchers | Careers | Sex differences | Life sciences | Research | Gender | Age | Optimism
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2011, Volume 2, p. 35
Within lymph nodes, non-hematopoietic stromal cells organize and interact with leukocytes in an immunologically important manner. In addition to organizing T... 
Human lymph nodes | Stromal cells | Tolerance | Mouse lymph nodes | Fibroblastic reticular cells | Lymph node stromal cells | Endothelial cells | fibroblastic reticular cells | endothelial cells | stromal cells | human lymph nodes | IMMUNOLOGY | tolerance | mouse lymph nodes | lymph node stromal cells | Stromal Cells | Endothelial Cells
Journal Article
Journal of cell science, ISSN 0021-9533, 10/2018, Volume 131, Issue 19, p. jcs214551
Cell migration is central to evoking a potent immune response. Dendritic cell (DC) migration to lymph nodes is dependent on the interaction of C-type... 
CLEC-2 | Dendritic cell | Migration | Membrane organization | Tetraspanin | TYROSINE PHOSPHATASE | LIPID RAFT MICRODOMAINS | ACTIVATION | SYK | TRAFFICKING | TSPANC8 TETRASPANINS | CELL BIOLOGY | DC-SIGN | EXPRESSION | ASSOCIATION
Journal Article
Immunological Reviews, ISSN 0105-2896, 05/2016, Volume 271, Issue 1, pp. 221 - 229
Summary A critical hallmark of adaptive immune responses is the rapid and extensive expansion of lymph nodes. During this process, the complex internal... 
fibroblastic reticular cells | dendritic cells | inflammation