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Nature Cell Biology, ISSN 1465-7392, 03/2012, Volume 14, Issue 3, pp. 318 - 328
Repair of DNA double-strand breaks is critical to genomic stability and the prevention of developmental disorders and cancer. A central pathway for this repair... 
TARGET | SPINDLE-CHECKPOINT | NUCLEAR RIBONUCLEOPROTEIN-G | REPAIR | STABILIZATION | TAO1 | DOUBLE-STRAND BREAKS | MAMMALIAN-CELLS | PROMOTES | EXPRESSION | CELL BIOLOGY | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Histone Chaperones - genetics | Humans | Histone Chaperones - metabolism | Homologous Recombination | Immunoblotting | Green Fluorescent Proteins - genetics | Gene Regulatory Networks | Nuclear Pore Complex Proteins - genetics | RNA Interference | Cell Cycle Proteins - genetics | RNA Precursors - metabolism | Nuclear Proteins - genetics | Rad51 Recombinase - metabolism | Green Fluorescent Proteins - metabolism | Rad51 Recombinase - genetics | Nuclear Pore Complex Proteins - metabolism | Cell Cycle Proteins - metabolism | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Nuclear Proteins - metabolism | RNA Precursors - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Genome, Human - genetics | Heterogeneous-Nuclear Ribonucleoproteins - genetics | Transcription Factors - metabolism | Poly(ADP-ribose) Polymerases - metabolism | BRCA2 Protein - metabolism | Poly(ADP-ribose) Polymerases - genetics | DNA Repair | Cell Line, Tumor | Models, Genetic | DNA Damage | BRCA2 Protein - genetics | Microscopy, Fluorescence | RNA-Binding Proteins - metabolism | Proteins | Physiological aspects | Research | Binding proteins | DNA damage | Ribonucleoproteins
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 43, pp. 18475 - 18480
Many proteins that respond to DNA damage are recruited to DNA lesions. We used a proteomics approach that coupled isotopic labeling with chromatin... 
Chromatin | Ultraviolet lasers | RNA | DNA damage | DNA | Stem cells | HeLa cells | Histones | Antibodies | Lesions | Damage signaling | MEL-18 | Polycomb repressive complex 1 | Polycomb repressive complex 2 | B lymphoma Mo-MLV insertion region 1 homolog (BMI1) | MONOUBIQUITINATED FANCD2 | MULTIDISCIPLINARY SCIENCES | damage signaling | polycomb repressive complex 1 | polycomb repressive complex 2 | DOUBLE-STRAND BREAKS | BRCA1 | IDENTIFICATION | REPAIR PROTEINS | CAENORHABDITIS-ELEGANS | GENE | PATHWAY | ATM | CELL | Chromatin - metabolism | Caenorhabditis elegans - metabolism | Humans | Mi-2 Nucleosome Remodeling and Deacetylase Complex - metabolism | Polycomb-Group Proteins | Caenorhabditis elegans - radiation effects | Ultraviolet Rays - adverse effects | Poly Adenosine Diphosphate Ribose - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Chromatin - radiation effects | DNA Repair | Proteomics | DNA Damage | HeLa Cells | In Vitro Techniques | Repressor Proteins - metabolism | Development and progression | Lymphomas | Cellular signal transduction | Genetic aspects | Research | Properties | Histone deacetylase | Transcription | proteomics | NuRD protein | Poly(ADP-ribose) polymerase | Mass spectroscopy | polycomb group proteins | DNA repair | DNA-directed RNA polymerase | Mammalian cells | Metastases | DNA helicase | Nucleoli | DNA-binding protein | Lasers | Ribose | Nucleosomes | Biological Sciences
Journal Article
Journal of Neurosurgery, ISSN 0022-3085, 04/2016, Volume 124, Issue 4, pp. 998 - 1007
Journal Article
Journal Article
Journal Article
NATURE, ISSN 0028-0836, 06/2019, Volume 570, Issue 7759, pp. 77 - 77
Journal Article
Journal Article
CIN: Computers, Informatics, Nursing, ISSN 1538-2931, 11/2009, Volume 27, Issue 6, pp. 393 - 397
Journal Article
Cell, ISSN 0092-8674, 08/2018, Volume 174, Issue 4, pp. 953 - 967.e22
Seminal yeast studies have established the value of comprehensively mapping genetic interactions (GIs) for inferring gene function. Efforts in human cells... 
CRISPR | functional genomics | epistasis | CRISPRi | genetic interactions | PLATFORM | VISUALIZATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | NETWORKS | IDENTIFICATION | MAMMALIAN-CELLS | SACCHAROMYCES-CEREVISIAE | GENOME | CELL BIOLOGY | Genetic research | Anopheles | DNA damage | Genes | Cells | Genetic interactions | Functional genomics
Journal Article