X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (637) 637
Book Chapter (135) 135
Publication (11) 11
Patent (8) 8
Book / eBook (4) 4
Newspaper Article (3) 3
Web Resource (2) 2
Book Review (1) 1
Conference Proceeding (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (398) 398
life sciences & biomedicine (382) 382
humans (304) 304
asthma (160) 160
respiratory system (154) 154
animals (127) 127
male (126) 126
immunology (117) 117
female (107) 107
inflammation (105) 105
abridged index medicus (85) 85
respiratory tract diseases (84) 84
gene expression (80) 80
middle aged (74) 74
asthma - drug therapy (68) 68
adult (66) 66
chronic obstructive pulmonary disease (64) 64
research (58) 58
general & internal medicine (56) 56
pharmacology & pharmacy (54) 54
oxidative stress (53) 53
mice (52) 52
allergy (51) 51
aged (46) 46
biochemistry & molecular biology (46) 46
copd (46) 46
cells, cultured (43) 43
critical care medicine (43) 43
health aspects (43) 43
analysis (42) 42
medicine (41) 41
lung diseases (40) 40
pulmonary disease, chronic obstructive - metabolism (39) 39
lung diseases, obstructive (38) 38
asthma - genetics (37) 37
corticosteroids (37) 37
proteins (37) 37
pulmonary disease, chronic obstructive - drug therapy (37) 37
11 medical and health sciences (35) 35
smoking (35) 35
biomarkers (33) 33
cell biology (33) 33
cytokines (33) 33
asthma - immunology (32) 32
review (32) 32
lung - metabolism (31) 31
risk factors (31) 31
disease models, animal (30) 30
glucocorticoids - pharmacology (30) 30
1103 clinical sciences (29) 29
asthma - metabolism (29) 29
signal transduction (29) 29
case-control studies (28) 28
cell line (28) 28
dexamethasone - pharmacology (28) 28
apoptosis (27) 27
research article (27) 27
adrenal cortex hormones - therapeutic use (26) 26
drug resistance (26) 26
kinases (26) 26
patients (26) 26
receptors, glucocorticoid - metabolism (26) 26
airway inflammation (25) 25
nf-kappa b - metabolism (25) 25
pulmonary disease, chronic obstructive - physiopathology (25) 25
asthma - physiopathology (24) 24
drug therapy (24) 24
glucocorticoids (24) 24
glucocorticoids - therapeutic use (24) 24
pulmonary disease, chronic obstructive - pathology (24) 24
respiratory tract (24) 24
tuberculosis (24) 24
care and treatment (23) 23
immunohistochemistry (23) 23
lungs (23) 23
pathogenesis (23) 23
gene expression regulation (22) 22
genetic aspects (22) 22
rodents (22) 22
severity of illness index (22) 22
smoking - adverse effects (22) 22
sputum (22) 22
macrophages (21) 21
neutrophils (21) 21
steroids (21) 21
treatment outcome (21) 21
1107 immunology (20) 20
anti-inflammatory agents - pharmacology (20) 20
anti-inflammatory agents - therapeutic use (20) 20
asthma - pathology (20) 20
clinical medicine (20) 20
disease (20) 20
studies (20) 20
1115 pharmacology and pharmaceutical sciences (19) 19
gene expression regulation - drug effects (19) 19
medical research (19) 19
mice, inbred c57bl (19) 19
acetylation (18) 18
biopsy (18) 18
cytokines - metabolism (18) 18
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (2) 2
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
Online Resources - Online (1) 1
Robarts - Stacks (1) 1
Scarborough Hospital - Online (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
St. Michael's College (John M. Kelly) - Chesterton (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The Lancet (British edition), ISSN 0140-6736, 2009, Volume 373, Issue 9678, pp. 1905 - 1917
Summary Glucocorticoid resistance or insensitivity is a major barrier to the treatment of several common inflammatory diseases—including chronic obstructive... 
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Transcription Factor AP-1 - drug effects | Glucocorticoids - therapeutic use | Transcriptional Activation - genetics | Transcription Factor AP-1 - genetics | Humans | Macrophage Migration-Inhibitory Factors - immunology | Transcriptional Activation - drug effects | Transcription Factor AP-1 - immunology | Histone Deacetylases - immunology | Transcriptional Activation - immunology | ATP-Binding Cassette, Sub-Family B, Member 1 - drug effects | Calcineurin Inhibitors | Macrophage Migration-Inhibitory Factors - genetics | Inflammation - drug therapy | Phosphodiesterase 4 Inhibitors | Anti-Inflammatory Agents - therapeutic use | Mitogen-Activated Protein Kinases - immunology | Genetic Predisposition to Disease - genetics | NF-kappa B - antagonists & inhibitors | Histone Deacetylases - genetics | Macrophage Migration-Inhibitory Factors - drug effects | Repressor Proteins - genetics | Histone Deacetylase 2 | Drug Resistance - drug effects | Inflammation - immunology | Asthma - drug therapy | ATP-Binding Cassette, Sub-Family B, Member 1 - immunology | Drug Resistance - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Drug Resistance - immunology | Repressor Proteins - immunology | Histone Deacetylases - drug effects | Mitogen-Activated Protein Kinases - genetics | Repressor Proteins - drug effects | Mitogen-Activated Protein Kinases - drug effects | Pulmonary Disease, Chronic Obstructive - drug therapy | Corticosteroids | Dosage and administration | Inflammation | Research | Drug resistance | Drug therapy | Health aspects | Complications and side effects | Risk factors | Inflammatory bowel disease | Proteins | Respiratory distress syndrome | Asthma | Steroids | Index Medicus | Abridged Index Medicus
Journal Article
2008, 1, ISBN 9780470058084, x, 292
Written by well-known experts in field, this is the first book dedicated to dealing with the single most challenging management issue in long-term steroid... 
Chemotherapy | Drug resistance | Respiratory organs | Steroid drugs | Diseases
Book
Journal of allergy and clinical immunology, ISSN 0091-6749, 09/2015, Volume 136, Issue 3, pp. 769 - 780
Background Inflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). Mitochondrial oxidative stress... 
Allergy and Immunology | airway hyperresponsiveness | antioxidant | proliferation | MitoQ | inflammation | mitochondria | airway smooth muscle | Ozone | oxidative stress | chronic obstructive pulmonary disease | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Respiratory System - pathology | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - pathology | Bronchial Hyperreactivity - genetics | Ubiquinone - pharmacology | Muscle, Smooth - drug effects | Smoking - physiopathology | Organophosphorus Compounds - pharmacology | Myocytes, Smooth Muscle - drug effects | Pneumonia - genetics | Pulmonary Disease, Chronic Obstructive - genetics | Bronchial Hyperreactivity - chemically induced | Signal Transduction | Mitochondria - pathology | Smoking - metabolism | Bronchial Hyperreactivity - pathology | Reactive Oxygen Species - antagonists & inhibitors | Electron Transport Chain Complex Proteins - metabolism | Pulmonary Disease, Chronic Obstructive - chemically induced | Respiratory System - drug effects | Airway Remodeling - genetics | Mice | Oxidative Stress - drug effects | Bronchial Hyperreactivity - drug therapy | Myocytes, Smooth Muscle - pathology | Pneumonia - pathology | Membrane Potential, Mitochondrial - drug effects | Pneumonia - chemically induced | Adult | Female | Pulmonary Disease, Chronic Obstructive - metabolism | Myocytes, Smooth Muscle - metabolism | Ubiquinone - analogs & derivatives | Gene Expression Regulation | Hydrogen Peroxide - pharmacology | Electron Transport Chain Complex Proteins - genetics | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Muscle, Smooth - metabolism | Animals | Pneumonia - drug therapy | Respiratory System - metabolism | Aged | Muscle, Smooth - pathology | Oxidative stress | Care and treatment | Lung diseases, Obstructive | Inflammation | Pharmaceutical industry | Biomedical research | Disease | Laboratories | Mortality | Colleges & universities | Smooth muscle | Mitochondrial DNA | Metabolism | Defects | Antioxidants | Mitochondria | Hospitals | Biopsy | Chronic obstructive pulmonary disease | Apoptosis | Smoking | Index Medicus | Abridged Index Medicus | NO, Nitric oxide | ΔΨm, Mitochondrial membrane potential | ASM, Airway smooth muscle | NAC, N-acetylcysteine | RL, Lung resistance | BAL, Bronchoalveolar lavage | OCR, Oxygen consumption rate | dTPP, Decyltriphenylphosphonium bromide | AHR, Airway hyperresponsiveness | logPC100, Concentration of acetylcholine that increased lung resistance by 100 | GOLD, Global Initiative for Chronic Obstructive Lung Disease | ATP, Adenosine triphosphate | KC, Keratinocyte-derived cytokine | JC-1, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide | COPD, Chronic obstructive pulmonary disease | ROS, Reactive oxygen species | Mechanisms of Allergy and Clinical Immunology
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 02/2017, Volume 139, Issue 2, pp. 519 - 532
Background Severe steroid-insensitive asthma is a substantial clinical problem. Effective treatments are urgently required, however, their development is... 
Allergy and Immunology | influenza | airway hyperresponsiveness | corticosteroids | PI3 kinase | Chlamydia species | histone deacetylase 2 | miR-21 | Severe asthma | respiratory syncytial virus | Haemophilus influenzae | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Influenza A Virus, H1N1 Subtype - immunology | Phosphorylation | Humans | Respiratory Syncytial Viruses - immunology | MicroRNAs - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Respiratory Tract Infections - genetics | Chlamydia muridarum - immunology | Asthma - immunology | Pneumonia - immunology | Proto-Oncogene Proteins c-akt - metabolism | Drug Resistance | Disease Models, Animal | Pneumonia - genetics | Histone Deacetylase 2 - genetics | PTEN Phosphohydrolase - genetics | Gene Expression Regulation | PTEN Phosphohydrolase - metabolism | Respiratory Tract Infections - drug therapy | Asthma - drug therapy | Asthma - genetics | Dexamethasone - therapeutic use | Animals | Pneumonia - drug therapy | Haemophilus influenzae - immunology | Respiratory Tract Infections - immunology | Mice | Mice, Inbred BALB C | MicroRNAs - genetics | Histone Deacetylase 2 - metabolism | Antagomirs - genetics | MicroRNA | Research institutes | Analysis | Asthma | Therapeutics | Health aspects | Homeopathy | Materia medica and therapeutics | Respiratory syncytial virus | Pathogenesis | Rodents | Influenza | Tumor necrosis factor-TNF | Chronic obstructive pulmonary disease | Infections | Inflammation | Viral infections | Steroids | Index Medicus | Abridged Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e95051 - e95051
..., National Heart & Lung Institute, Imperial College London, London, United Kingdom Ian M. Adcock * E-mail: ian.adcock@imperial.ac.uk Affiliation: Airways Disease Section... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Inflammation - chemically induced | Cell Line | Interleukin-1beta - pharmacology | Enzyme-Linked Immunosorbent Assay | Epithelial Cells - drug effects | Humans | Hydrogen Peroxide - pharmacology | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Inflammation - metabolism | Chromatin Immunoprecipitation | Epithelial Cells - immunology | Nuclear Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Cell Cycle Proteins | Protein-Serine-Threonine Kinases - metabolism | Oxidative stress | Chromatin | Immunoprecipitation | Hydrogen peroxide | Disease | Epithelial cells | Gene regulation | Recruitment | Interleukin 6 | Proteins | Respiratory tract | Rodents | Cell cycle | Interleukin 1 | Histones | Chronic obstructive pulmonary disease | Inhibition | Pretreatment | Acetylation | Interleukin 8 | Enzyme-linked immunosorbent assay | NF-κB protein | Lung diseases | Inflammation | siRNA | RNA polymerase | Gene expression | Disease control | Promoters | Polymerase chain reaction | Inhibitors | Obstructive lung disease | Cell lines | Cancer | Index Medicus
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 03/2017, Volume 139, Issue 3, pp. 780 - 789
Journal Article
by McManus, Richard J and Mant, Jonathan and Franssen, Marloes and Nickless, Alecia and Schwartz, Claire and Hodgkinson, James and Bradburn, Peter and Farmer, Andrew and Grant, Sabrina and Greenfield, Sheila M and Heneghan, Carl and Jowett, Susan and Martin, Una and Milner, Siobhan and Monahan, Mark and Mort, Sam and Ogburn, Emma and Perera-Salazar, Rafael and Shah, Syed Ahmar and Yu, Ly-Mee and Tarassenko, Lionel and Hobbs, F D Richard and Bradley, Brendan and Lovekin, Chris and Judge, David and Castello, Luis and Dawson, Maureen and Brice, Rebecca and Dunbabin, Bethany and Maslen, Sophie and Rutter, Heather and Norris, Mary and French, Lauren and Loynd, Michael and Whitbread, Pippa and Saldana Ortaga, Luisa and Noel, Irene and Madronal, Karen and Timmins, Julie and Hughes, Lucy and Hinks, Beth and Bailey, Sheila and Read, Sue and Weston, Andrea and Spannuth, Somi and Maiden, Sue and Chermahini, Makiko and McDonald, Ann and Rajan, Shelina and Allen, Sue and Deboys, Brenda and Fell, Kim and Johnson, Jenny and Jung, Helen and Lister, Rachel and Osborne, Ruth and Secker, Amy and Qasim, Irene and William, Kirsty and Harris, Abi and Zhao, Susan and Butcher, Elaine and Darbyshire, Pauline and Joshi, Sarah and Davies, Jon and Talbot, Claire and Hoverd, Eleanor and Field, Linda and Adcock, Tracey and Rooney, Julia and Cooter, Nina and Butler, Aaron and Allen, Naomi and Abdul-Wahab, Maria and McNicholas, Kathryn and Peniket, Lara and Dodd, Kate and Mugurza, Julie and Baskerville, Richard and Syed, Rakshan and Bailey, Clare and Adams, Jill and Uglow, Paul and Townsend, Neil and Macleod, Alison and Hawkins, Charlotte and Behura, Suparna and Crawshaw, Jonathan and Fox, Robin and Doski, Waleed and Aylward, Martin and A'Court, Christine and Rapley, David and Walsh, Jo and Batra, Paul and Seoane, Ana and Mukherjee, Sluti and Dixon, Jonathan and Arthur, Peter and Sutcliffe, Karen and ... and TASMINH4 investigators and TASMINH4 Investigators
The Lancet (British edition), ISSN 0140-6736, 03/2018, Volume 391, Issue 10124, pp. 949 - 959
Journal Article