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1. Full Text Naturally occurring canine melanoma as a predictive comparative oncology model for human mucosal and other triple wild-type melanomas
by Hernandez, Belen and Adissu, Hibret A and Wei, Bih-Rong and Michael, Helen T and Merlino, Glenn and Mark Simpson, R
International journal of molecular sciences, ISSN 1661-6596, 02/2018, Volume 19, Issue 2, p. 394
Signal transduction | Translational research | Kinase inhibition | Precision medicine | Immunotherapy | Dogs | Comparative genomics | Clinical trial design | Drug development | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | TOR protein | Animal models | Copy number | Mucosa | Clinical trials | Neurofibromin 1 | Homology | AKT protein | Neuroblastoma | Kinases | Gene sequencing | Proteins | Alterations | Annotations | Mathematical models | Genotypes | Medical research | Sarcoma | Immunomodulation | Melanoma | MAP kinase | Rapamycin | Decoding | 1-Phosphatidylinositol 3-kinase | Tumor suppressor genes | Transduction | Mutation | Protein structure | Structure-function relationships | Index Medicus | signal transduction | immunotherapy | dogs | drug development | clinical trial design | precision medicine | translational research | Review | kinase inhibition | comparative genomics
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2. Full Text The Price of “Humanization”
by Adissu, Hibret A
Veterinary pathology, ISSN 0300-9858, 1/2021, Volume 58, Issue 1, pp. 7 - 9
Pathology | Veterinary Sciences | Life Sciences & Biomedicine | Science & Technology | Mice | Animals | Humans | Hematopoietic Stem Cells | Index Medicus
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3. Full Text Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma
by Shao, Yang W and Wood, Geoffrey A and Lu, Jinchang and Tang, Qing-Lian and Liu, Jonathan and Molyneux, Sam and Chen, Yan and Fang, Hui and Adissu, Hibret and McKee, Trevor and Waterhouse, Paul and Khokha, Rama
Oncogene, ISSN 0950-9232, 01/2019, Volume 38, Issue 2, pp. 291 - 298
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Care and treatment | Osteosarcoma | Development and progression | Tumor suppressor genes | Genetic aspects | Gene expression | Health aspects | Clonal deletion | Copy number | Genomics | Cell division | Tumorigenesis | Genetic engineering | Bone tumors | Species | Cell migration | Cancer | Index Medicus | Brief Communication | Bone cancer | Cancer genomics
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4. Full Text Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: Example of the breast epithelium
by Plachot, Cedric and Chaboub, Lesley S and Adissu, Hibret A and Wang, Lei and Urazaev, Albert and Sturgis, Jennifer and Asem, Elikplimi K and Lelièvre, Sophie A
BMC biology, ISSN 1741-7007, 11/2009, Volume 7, Issue 1, pp. 77 - 77
Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Collagen Type IV - metabolism | Cell Line | Mammary Glands, Human - cytology | Signal Transduction | Humans | Basement Membrane - metabolism | Epithelial Cells - physiology | High-Throughput Screening Assays | Breast | Cell Polarity - physiology | Female | Mammary Glands, Human - physiology | Cell Culture Techniques | Epithelial Cells - cytology | Spheroids, Cellular | Cell Differentiation - physiology | Laminin | Physiological aspects | Models | Polarity (Biology) | Research | Epithelium | Human cell culture | Proteins | Medical research | Experiments | Manuscripts | Cell cycle | Cancer | Index Medicus | Methodology article
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5. Full Text Cancer incidence profile in sub‐Saharan African‐born blacks in the United States: Similarities and differences with US‐born non‐Hispanic blacks
by Medhanie, Genet A and Fedewa, Stacey A and Adissu, Hibret and DeSantis, Carol E and Siegel, Rebecca L and Jemal, Ahmedin
Cancer, ISSN 0008-543X, 08/2017, Volume 123, Issue 16, pp. 3116 - 3124
sub‐Saharan | non‐Hispanic | blacks | Africa | proportional incidence ratio | non-Hispanic | sub-Saharan | Life Sciences & Biomedicine | Oncology | Science & Technology | United States - epidemiology | Africa, Eastern - ethnology | Humans | Middle Aged | Thyroid Neoplasms - epidemiology | Male | Incidence | Young Adult | Liver Neoplasms - epidemiology | Adult | Female | Stomach Neoplasms - epidemiology | Emigrants and Immigrants | Sarcoma, Kaposi - epidemiology | Leukemia - epidemiology | Colorectal Neoplasms - epidemiology | SEER Program | Lymphoma, Non-Hodgkin - epidemiology | Prostatic Neoplasms - epidemiology | African Continental Ancestry Group - statistics & numerical data | African Americans - statistics & numerical data | Lung Neoplasms - epidemiology | Sex Factors | Africa South of the Sahara - ethnology | Africa, Western - ethnology | Aged | Neoplasms - epidemiology | Prevention | Social classes | Cancer patients | Demographic aspects | Analysis | Diagnosis | Social aspects | Health aspects | Cancer | Control methods | Leukemia | Liver | Lung cancer | Bladder | Infections | Thyroid gland | Birth | Epidemiology | Blood | Confidence intervals | Liver cancer | Urinary bladder | Etiology | Larynx | Genetic factors | Age | Thyroid | Stomach | Sarcoma | Lymphoma | Childbirth & labor | Oral cavity | Thyroid cancer | Men | Health risk assessment | Females | Prostate cancer | Prostate | Smoking | Index Medicus | Abridged Index Medicus
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6. Full Text Polymer–lipid hybrid nanoparticles synchronize pharmacokinetics of co-encapsulated doxorubicin–mitomycin C and enable their spatiotemporal co-delivery and local bioavailability in breast tumor
by Zhang, Rui Xue, MSc and Cai, Ping, MD and Zhang, Tian, BSc and Chen, King, BSc in Pharmacy and Li, Jason, MASc and Cheng, Ji, PhD and Pang, K. Sandy, Prof. PhD and Adissu, Hibret A., DVM, PhD, DACVP and Rauth, Andrew M., Prof. PhD and Wu, Xiao Yu, Prof. PhD
Nanomedicine, ISSN 1549-9634, 2015, Volume 12, Issue 5, pp. 1279 - 1290
Internal Medicine | Ratiometric delivery | Doxorubicin combination | Pharmacokinetics | Biodistribution | Polymer–lipid nanoparticles | Polymer-lipid nanoparticles | Science & Technology - Other Topics | Nanoscience & Nanotechnology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Humans | Biological Availability | Drug Resistance, Neoplasm | Lipids | Breast Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Drug Synergism | Nanoparticles | Tissue Distribution | Animals | Cell Line, Tumor | Antineoplastic Agents - pharmacokinetics | Mice | Mitomycin - pharmacokinetics | Polymers | Mitomycin - administration & dosage | Doxorubicin - administration & dosage | Chemotherapy | Anthracyclines | Mitomycin | Breast cancer | Drug therapy, Combination | Polymer industry | Cancer | Drugstores | Polyols | Metabolites | Pharmacy | Mass spectrometry | High performance liquid chromatography | Index Medicus
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7. Full Text Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer
by Adissu, Hibret A and McKerlie, Colin and Di Grappa, Marco and Waterhouse, Paul and Xu, Qiang and Fang, Hui and Khokha, Rama and Wood, Geoffrey A
The Prostate, ISSN 0270-4137, 12/2015, Volume 75, Issue 16, pp. 1831 - 1843
metalloproteinases | macrophages | cytokines | tissue inhibitor of metalloproteinase 3 | Endocrinology & Metabolism | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Inflammation - pathology | PTEN Phosphohydrolase - genetics | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Matrix Metalloproteinase 2 - metabolism | PTEN Phosphohydrolase - metabolism | Male | Disease Progression | Prostate - metabolism | Mice, Knockout | Matrix Metalloproteinase 2 - genetics | Prostate - pathology | Inflammation - metabolism | Matrix Metalloproteinase 9 - metabolism | Animals | Prostatic Neoplasms - genetics | Matrix Metalloproteinase 9 - genetics | Neoplasm Invasiveness - pathology | Tissue Inhibitor of Metalloproteinase-3 - metabolism | Inflammation - genetics | Mice | Neoplasm Invasiveness - genetics | Disease Models, Animal | Tissue Inhibitor of Metalloproteinase-3 - genetics | Immunohistochemistry | COX-2 inhibitors | Proteases | Analysis | Prostatitis | Inflammation | Prostate cancer | Tumors | Index Medicus
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8. Full Text Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism
by Matsumoto, Yoshinori and La Rose, Jose and Lim, Melissa and Adissu, Hibret A and Law, Napoleon and Mao, Xiaohong and Cong, Feng and Mera, Paula and Karsenty, Gerard and Goltzman, David and Changoor, Adele and Zhang, Lucia and Stajkowski, Megan and Grynpas, Marc D and Bergmann, Carsten and Rottapel, Robert
The Journal of clinical investigation, ISSN 0021-9738, 06/2017, Volume 127, Issue 7, pp. 2612 - 2625
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Osteocalcin - biosynthesis | Axin Protein - genetics | Signal Transduction | Humans | Osteocalcin - genetics | Ubiquitin-Protein Ligases - metabolism | Bone Development | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Animals | Energy Metabolism | Core Binding Factor Alpha 1 Subunit - biosynthesis | Cleidocranial Dysplasia - genetics | Axin Protein - biosynthesis | Mice | Cleidocranial Dysplasia - metabolism | Osteoblasts - metabolism | Ubiquitin-Protein Ligases - genetics | Core Binding Factor Alpha 1 Subunit - genetics | Ubiquitin | Dysplasia | Dosage and administration | Genetic aspects | Research | Gene expression | Drug therapy | Energy metabolism | Transcription factors | Bone (intramembranous) | Adipocytes | Osteoblasts | Bone growth | Embryogenesis | Cell growth | Mineralization | Rodents | Fibroblasts | Bone dysplasia | Bones | Fibroblast growth factor 18 | Catenin | Growth factors | Osteopenia | Ubiquitin-protein ligase | Adipogenesis | Cbfa-1 protein | Osteocalcin | Craniofacial syndromes | Embryo fibroblasts | Metabolism | Hereditary diseases | Osteoblastogenesis | Protein expression | Mutation | Osteogenesis | Cancer | Index Medicus | Abridged Index Medicus
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9. Full Text Topical Application of Culture‐Expanded CD34+ Umbilical Cord Blood Cells from Frozen Units Accelerates Healing of Diabetic Skin Wounds in Mice
by Whiteley, Jennifer and Chow, Theresa and Adissu, Hibret and Keating, Armand and Rogers, Ian M
Stem cells translational medicine, ISSN 2157-6564, 08/2018, Volume 7, Issue 8, pp. 591 - 601
Diabetes | Umbilical cord blood | Skin ulcer | Stem cells | Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell culture | Flow cytometry | Stem cell transplantation | Paracrine signalling | Blood | Stem cell factor | Angiogenesis | Cord blood | Fibroblasts | Bone marrow | Diabetes mellitus (non-insulin dependent) | Growth factors | CD34 antigen | Wound healing | Cytokines | Tissue engineering | Blood cells | Neutrophils | Inflammation | Trauma | Ulcers | Ligands | Umbilical cord | Topical application | Index Medicus | Tissue-specific Progenitor and Stem cells | Tissue‐Specific Progenitor and Stem Cells | Translational s and Reviews | Tissue Specific Stem Cells | Epidermal Regeneration | Hematopoietic Stem | Progenitor Cells
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10. Full Text The voltage‐gated proton channel Hv1/VSOP inhibits neutrophil granule release
by Okochi, Yoshifumi and Aratani, Yasuaki and Adissu, Hibret A and Miyawaki, Nana and Sasaki, Mari and Suzuki, Kazuo and Okamura, Yasushi
Journal of leukocyte biology, ISSN 0741-5400, 01/2016, Volume 99, Issue 1, pp. 7 - 19
proton channel | inflammation | Proton channel | Inflammation | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | Lung - microbiology | Lung - pathology | NADPH Oxidases - metabolism | Neutrophils - immunology | Secretory Vesicles - metabolism | Ion Channels - genetics | Cell Degranulation - immunology | Exocytosis | Mice, Knockout | Protein Transport | Animals | Cell Degranulation - genetics | Ion Channels - metabolism | Immunoglobulin G - immunology | Cytoplasmic Granules - metabolism | Protein Binding | Female | Cell Membrane - metabolism | Lung - metabolism | Mice | Neutrophils - metabolism | Lung - immunology | Peroxidase - metabolism | Index Medicus
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