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2016, ISBN 2889197204
Web Resource
Journal of Alzheimer's Disease, ISSN 1387-2877, 2018, Volume 62, Issue 3, pp. 1369 - 1379
It is estimated that by the year 2050 there will be more than 1.5 billion people globally over the age of 65 years. Aging is associated with changes to a... 
therapeutic | copper | iron | metals | clinical trials | Alzheimer's disease | zinc | TARGETING A-BETA | NEUROFIBRILLARY TANGLES | CONTROLLED-TRIAL | AMYLOID PRECURSOR PROTEIN | NEUROSCIENCES | COGNITIVE DECLINE | ZINC-DEFICIENCY | IN-VIVO | DESFERRIOXAMINE B | BRAIN IRON | PARKINSONS-DISEASE
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2019, Volume 514, Issue 3, pp. 888 - 892
Human amyloid-β (Aβ ) and rat Aβ have lower affinity for extracellular Zn than human Aβ . Here we report extracellular Zn -independent attenuation of dentate... 
Rat amyloid β1-42 | Dentate gyrus LTP | Human amyloid β1-40 | Zn2
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2019, Volume 514, Issue 3, p. 888
Human amyloid-[beta].sub.1-40 (A[beta].sub.1-40) and rat A[beta].sub.1-42 have lower affinity for extracellular Zn.sup.2+ than human A[beta].sub.1-42. Here we... 
Zinc compounds
Journal Article
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 03/2018, Volume 62, Issue 3, pp. 1369 - 1379
It is estimated that by the year 2050 there will be more than 1.5 billion people globally over the age of 65 years. Aging is associated with changes to a... 
Elderly people | Brain | Neurodegenerative diseases | Pathogenesis | Metals | Medical services | Disorders | Clinical trials | Homeostasis | Tissues | Risk factors | Aging | Elderly | Alzheimer's disease | Age | Geriatrics | Metal ions
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 05/2015, Volume 46, Issue 2, pp. 297 - 311
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e17669
We have previously demonstrated that brief treatment of APP transgenic mice with metal ionophores (PBT2, Prana Biotechnology) rapidly and markedly improves... 
CAMKII | ABNORMALITIES | BIOLOGY | A-BETA | LONG-TERM POTENTIATION | ACCUMULATION | MICROSCOPY | MOLECULAR-BASIS | TRANSGENIC MICE | KINASE-II | PLASTICITY | Memory - drug effects | Clioquinol - analogs & derivatives | Ionophores - administration & dosage | Cells, Cultured | Mice, Transgenic | Hippocampus - pathology | Neurites - metabolism | Hippocampus - drug effects | Alzheimer Disease - pathology | Nerve Tissue Proteins - metabolism | Animals | Synapses - metabolism | Metals - administration & dosage | Dendritic Spines - drug effects | Dendritic Spines - pathology | Alzheimer Disease - metabolism | Female | Mice | Neurogenesis - drug effects | Ionophores - pharmacology | Neurites - drug effects | Disease Models, Animal | Metals - pharmacology | Proteins | Genetically modified animals | Physiological aspects | Animal genetic engineering | Alzheimer's disease | Ionophores | Brain | Cell culture | Spine | Memory | Cognitive ability | Neurobiology | Glutamic acid receptors | Synaptic density | Density | Learning | Drug dosages | Medical research | Neurodegenerative diseases | Axonogenesis | Medical treatment | Pathology | Morphology | β-Amyloid | Hippocampus | Biotechnology | Neurosciences | Laboratories | Metals | Mental health | Clinical trials | Biology | Kinases | Dendritic spines | Transgenic animals | Rodents | Oxidation | Trends | Incubation | Neurons | Transgenic mice | N-Methyl-D-aspartic acid receptors | Zinc | Brain research | Brain-derived neurotrophic factor | Spinophilin | Alzheimers disease | Potassium | Ca2+/calmodulin-dependent protein kinase II | Animal cognition
Journal Article
FRONTIERS IN NEUROSCIENCE, ISSN 1662-453X, 12/2018, Volume 12, p. 981
Traumatic brain injury (TBI) consists of acute and long-term pathophysiological sequelae that ultimately lead to cognitive and motor function deficits, with... 
OXIDATIVE DAMAGE | ALZHEIMERS-DISEASE | traumatic brain injury | neurodegeneration | metals | SUBSTANTIA-NIGRA | NEUROSCIENCES | COGNITIVE DYSFUNCTION | DEFEROXAMINE | inflammation | CEREBRAL MICROBLEEDS | INTRACEREBRAL HEMORRHAGE | iron | HEME OXYGENASE-1 HO-1 | ACCUMULATION | oxidative stress | PARKINSONS-DISEASE | Brain | Phenotype | Nervous system | Iron in the body | Degeneration | Research | Injuries | Risk factors
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 8
Neuronal amyloid β1–42 (Aβ1–42) accumulation is considered an upstream event in Alzheimer’s disease pathogenesis. Here we report the mechanism on synaptic... 
Tetrodotoxin | Genistein | Granule cells | Brain slice preparation | Cognitive ability | Injection | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors | Chlorpromazine | Zinc | Dentate gyrus | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid | Plasma membranes | Ion channels | Hippocampus
Journal Article