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SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 1 - 17
Journal Article
Nature Communications, ISSN 2041-1723, 12/2020, Volume 11, Issue 1, pp. 1 - 1
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Sleep disorders | Phenotypes | Orexins | Lymphocytes | Narcolepsy | Lymphocytes T | CD4 antigen
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7578, pp. 379 - 383
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 11/2019, Volume 10, Issue 1, pp. 1 - 17
Individuals with narcolepsy suffer from abnormal sleep patterns due to loss of neurons that uniquely supply hypocretin (HCRT). Previous studies found... 
AUTOANTIBODIES | MULTIMERS | SYSTEM | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | COMPLEXES | SEQUENCE | CATAPLEXY | RECEPTORS | ONSET | REVEALS | Antigens | Phenotypes | Orexins | Effector cells | Lymphocytes T | Leukocytes | CD4 antigen | T-cell receptor | Sleep disorders | Sleep | Lymphocytes | Alleles | Narcolepsy | Histocompatibility antigen HLA | In vivo methods and tests | Expansion
Journal Article
The Plant Cell, ISSN 1040-4651, 10/2012, Volume 24, Issue 10, pp. 3921 - 3948
Journal Article
ONCOGENE, ISSN 0950-9232, 01/2020, Volume 39, Issue 1, pp. 164 - 175
Citrin, encoded by SLC25A13 gene, is an inner mitochondrial transporter that is part of the malate-aspartate shuttle, which regulates the NAD+/NADH ratio... 
ASPARTATE | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | EXPERIENCE | CANCER | DEFICIENCY | CELL BIOLOGY | Carbohydrates | Phosphorylation | Phenotypes | Autophagy | Cytosol | Carcinogenesis | NAD | Mitochondria | NADH | Oxidative phosphorylation | Glycolysis | Mutation | Phagocytosis | Cancer | Index Medicus | Optics | Physics
Journal Article
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7680, pp. 384 - 388
The branched-chain amino acid (BCAA) pathway and high levels of BCAA transaminase 1 (BCAT1) have recently been associated with aggressiveness in several cancer... 
AMINO-ACID-METABOLISM | IDH2 MUTATIONS | 5-METHYLCYTOSINE | MULTIDISCIPLINARY SCIENCES | METHYLATION DATA | HYDROXYLATION | PROLIFERATION | ACUTE MYELOID-LEUKEMIA | DIFFERENTIATION | CANCER PROGRESSION | COMPREHENSIVE ANALYSIS | Cell Proliferation | Prognosis | Amino Acids, Branched-Chain - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Molecular Targeted Therapy | DNA-Binding Proteins - metabolism | DNA Methylation | Leukemia, Myeloid, Acute - enzymology | Neoplastic Stem Cells - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Proteolysis | Transaminases - metabolism | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Female | Ketoglutaric Acids - metabolism | Transaminases - deficiency | Proto-Oncogene Proteins - metabolism | Leukemia, Myeloid, Acute - pathology | Transaminases - genetics | Isocitrate Dehydrogenase - genetics | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Epistasis, Genetic | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Proteomics | Isocitrate Dehydrogenase - metabolism | Mice | Mutation | Medical and Health Sciences | Medicin och hälsovetenskap | Leukemia, Myeloid, Acute | Hypoxia-Inducible Factor 1, alpha Subunit | Journal Article | Research Support, U.S. Gov't, Non-P.H.S | Proto-Oncogene Proteins | Isocitrate Dehydrogenase | DNA-Binding Proteins | Basic Medicine | Cell and Molecular Biology | Hypoxia-Inducible Factor-Proline Dioxygenases | Neoplastic Stem Cells | Transaminases | Amino Acids, Branched-Chain | Medicinska och farmaceutiska grundvetenskaper | Ketoglutaric Acids | Cell- och molekylärbiologi
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 03/2017, Volume 8, p. 319
Journal Article
Cell, ISSN 0092-8674, 09/2018, Volume 174, Issue 6, pp. 1559 - 1570.e22
The urea cycle (UC) is the main pathway by which mammals dispose of waste nitrogen. We find that specific alterations in the expression of most UC enzymes... 
cancer metabolism | pyrimidines | urea cycle | mutagenesis | CAD | immunotherapy | CTLA-4 BLOCKADE | HEPATOCELLULAR-CARCINOMA | OROTIC-ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | PATIENT | PYRIMIDINE SYNTHESIS | IDENTIFICATION | CANCER | BINDING | PROGRESSION | PREDICTION | CELL BIOLOGY | Neoplasms - metabolism | Metabolomics | TOR Serine-Threonine Kinases - metabolism | Dihydroorotase - genetics | Aspartate Carbamoyltransferase - metabolism | Genomics | Humans | Ornithine Carbamoyltransferase - genetics | Pyrimidines - biosynthesis | Ornithine Carbamoyltransferase - antagonists & inhibitors | Pyrimidines - chemistry | TOR Serine-Threonine Kinases - antagonists & inhibitors | RNA Interference | Female | Ornithine Carbamoyltransferase - metabolism | Urea - metabolism | Dihydroorotase - metabolism | Phosphorylation - drug effects | Aspartate Carbamoyltransferase - genetics | Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) - metabolism | Mice, Inbred C57BL | Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) - genetics | Mice, SCID | Sirolimus - pharmacology | Animals | Cell Line, Tumor | Mice | Amino Acid Transport Systems, Basic - metabolism | Neoplasms - pathology | RNA, Small Interfering - metabolism | Urea | Pyrimidines | Metabolites | Immunotherapy | Refuse and refuse disposal | Resveratrol | Physiological aspects | Nucleotides
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 02/2019, Volume 79, Issue 3, pp. 518 - 533
Downregulation of the urea cycle enzyme argininosuccinate synthase (ASS1) by either promoter methylation or by HIF1 alpha is associated with increased... 
EXERCISE TEST | GLUTAMINE | AMMONIA | GENE | ONCOLOGY | LIVER | DYSREGULATED PH | CELL-GROWTH | HYPOXIA
Journal Article