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PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 8, pp. e72301 - e72301
Progressive aggregation of protein Tau into oligomers and fibrils correlates with cognitive decline and synaptic dysfunction, leading to neurodegeneration in... 
NEUROFIBRILLARY TANGLES | IMMUNOTHERAPY | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | AMYLOID-BETA-PEPTIDE | MOUSE MODEL | PATHOLOGY | CONFORMATION | PASSIVE-IMMUNIZATION | BRAIN | DEGENERATION | Phosphoproteins - immunology | Phosphorylation | Tauopathies - immunology | tau Proteins - immunology | Humans | Vaccination | Peptides - administration & dosage | Phosphoproteins - chemical synthesis | Peptides - chemical synthesis | tau Proteins - genetics | Tauopathies - physiopathology | tau Proteins - antagonists & inhibitors | Alzheimer Vaccines - immunology | Disease Models, Animal | Brain - physiopathology | Peptides - immunology | Alzheimer Vaccines - administration & dosage | Mice, Transgenic | Treatment Outcome | Psychomotor Performance - drug effects | Brain - drug effects | Liposomes - chemistry | Animals | Mice | Tauopathies - drug therapy | Brain - immunology | Antibodies, Neutralizing - blood | Phosphoproteins - administration & dosage | Oligomers | Medical research | Peptides | Medicine, Experimental | Disease susceptibility | Vaccines | Alzheimer's disease | Antigenic determinants | Brain | Neurosciences | Cognitive ability | Clinical trials | Lipids | Antisera | Proteins | Neurodegeneration | Transgenic animals | Immunotherapy | Rodents | Genetics | Neurodegenerative diseases | Medical treatment | Fibrils | Pharmacology | Pathology | Tau protein | Liposomes | Mutation | Alzheimers disease | Animal cognition | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2011, Volume 286, Issue 10, pp. 8585 - 8596
The identification of toxic Aβ species and/or the process of their formation is crucial for understanding the mechanism(s) of Aβ neurotoxicity in Alzheimer... 
Oligomers | Molecular Bases of Disease | Protein Self-assembly | Neurodegeneration | Cell Death | Amyloid | Alzheimer Disease | Nucleated Polymerization
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1 - 15
The aggregation of intracellular tau protein is a major hallmark of Alzheimer’s disease (AD). The extent and the stereotypical spread of tau pathology in the... 
Brain | Oligomerization | Tau protein | Site selection | Proteolysis | Edman degradation | Cognitive ability | Mass spectroscopy | Calpain | Alzheimer's disease
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2006, Volume 12, Issue 23, pp. 3729 - 3735
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2012, Volume 32, Issue 28, pp. 9677 - 9689
Passive immunization against beta-amyloid (A beta) has become an increasingly desirable strategy as a therapeutic treatment for Alzheimer's disease (AD).... 
APP TRANSGENIC MICE | NATURAL OLIGOMERS | HUMAN IGG1 | ALZHEIMERS-DISEASE | PROTEIN-KINASE | LONG-TERM POTENTIATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | PASSIVE-IMMUNIZATION | SECRETED OLIGOMERS | P38 MAP KINASE | Microglia - metabolism | Humans | Middle Aged | Male | Green Fluorescent Proteins - genetics | Neuroprotective Agents - metabolism | Alzheimer Disease - pathology | Neuroprotective Agents - pharmacology | Time Factors | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Statistics, Nonparametric | Aged, 80 and over | Neurons - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Alzheimer Disease - immunology | Receptors, Chemokine - genetics | Plaque, Amyloid - immunology | Disease Models, Animal | Animals, Newborn | Rats | Mice, Transgenic | Mutation - genetics | Rats, Sprague-Dawley | Microscopy, Confocal | Plaque, Amyloid - metabolism | Mice | CX3C Chemokine Receptor 1 | Alzheimer Disease - blood | Immunoglobulin G - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dose-Response Relationship, Immunologic | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Immunoglobulin G - pharmacology | Female | Neurons - drug effects | Peptide Fragments - metabolism | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Plaque, Amyloid - pathology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Alzheimer Disease - therapy | Cells, Cultured | Presenilin-1 - genetics | Hippocampus - cytology | Gene Expression Regulation - drug effects | Amyloid beta-Protein Precursor - genetics | Animals | Amyloid beta-Peptides - immunology | Aged | Index Medicus
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2017, Volume 56, Issue 2, pp. 585 - 599
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, pp. 39374 - 39374
Accumulation of amyloid-beta (A beta) peptides and amyloid plaque deposition in brain is postulated as a cause of Alzheimer's disease (AD). The precise... 
PROTEIN | FIBRILS | ATOMIC-RESOLUTION STRUCTURE | ALZHEIMERS-DISEASE | AMYLOID-BETA | MULTIDISCIPLINARY SCIENCES | X-RAY-DIFFRACTION | ANTIBODY | CONFORMATION | OLIGOMERS | PEPTIDE
Journal Article
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P1296 - P1296
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2018, Volume 8, Issue 1, pp. 16725 - 16725
The aggregation of intracellular tau protein is a major hallmark of Alzheimer's disease (AD). The extent and the stereotypical spread of tau pathology in the... 
NEUROFIBRILLARY TANGLES | TRAUMATIC BRAIN-INJURY | MULTIDISCIPLINARY SCIENCES | NEUTRAL PROTEINASE CALPAIN | IN-VIVO | PAIRED HELICAL FILAMENTS | NEURODEGENERATION | RAT-BRAIN | PROTEOLYSIS | PATHOLOGY | CLEAVAGE
Journal Article
Plant Physiology, ISSN 0032-0889, 1/2015, Volume 167, Issue 1, pp. 251 - 261
The secondary metabolite sulforaphane is produced during the hypersensitive response and is involved in protection against infections . Plants defend... 
Journal Article
by Acharya, S and Acosta, F T and Adamová, D and Adolfsson, J and Aggarwal, M M and Aglieri Rinella, G and Agnello, M and Agrawal, N and Ahammed, Z and Ahn, S U and Aiola, S and Akindinov, A and Al-Turany, M and Alam, S N and Albuquerque, D S. D and Aleksandrov, D and Alessandro, B and Alfaro Molina, R and Ali, Y and Alici, A and Alkin, A and Alme, J and Alt, T and Altenkamper, L and Altsybeev, I and Andrei, C and Andreou, D and Andrews, H A and Andronic, A and Angeletti, M and Anguelov, V and Anson, C and Antičić, T and Antinori, F and Antonioli, P and Apadula, N and Aphecetche, L and Appelshäuser, H and Arcelli, S and Arnaldi, R and Arnold, O W and Arsene, I C and Arslandok, M and Audurier, B and Augustinus, A and Averbeck, R and Azmi, M D and Badalà, A and Baek, Y W and Bagnasco, S and Bailhache, R and Bala, R and Baldisseri, A and Ball, M and Baral, R C and Barbano, A M and Barbera, R and Barile, F and Barioglio, L and Barnaföldi, G G and Barnby, L S and Barret, V and Bartalini, P and Barth, K and Bartsch, E and Bastid, N and Basu, S and Batigne, G and Batyunya, B and Batzing, P C and Bazo Alba, J L and Bearden, I G and Beck, H and Bedda, C and Behera, N K and Belikov, I and Bellini, F and Bello Martinez, H and Bellwied, R and Beltran, L G. E and Belyaev, V and Bencedi, G and Beole, S and Bercuci, A and Berdnikov, Y and Berenyi, D and Bertens, R A and Berzano, D and Betev, L and Bhaduri, P P and Bhasin, A and Bhat, I R and Bhattacharjee, B and Bhom, J and Bianchi, A and Bianchi, L and Bianchi, N and Bielčík, J and Bielčíková, J and Bilandzic, A and ... and ALICE Collaboration and The ALICE collaboration and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and eSSENCE: The e-Science Collaboration and Lund University and Partikelfysik and Lunds universitet and Particle Physics
Journal of High Energy Physics, ISSN 1126-6708, 11/2018, Volume 2018, Issue 11, pp. 1 - 33
Journal Article