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1. Full Text MDS: Roadblock to differentiation
by Agarwal, Anupriya
Blood, ISSN 0006-4971, 09/2012, Volume 120, Issue 10, pp. 1968 - 1969
Life Sciences & Biomedicine | Hematology | Science & Technology | Myelodysplastic Syndromes - genetics | Chromosomes, Human, Pair 7 - genetics | Humans | STAT3 Transcription Factor - genetics | Chromosome Aberrations | Hematopoietic Stem Cells | Index Medicus | Abridged Index Medicus
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2. Full Text Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
by Corbin, Amie S and Agarwal, Anupriya and Loriaux, Marc and Cortes, Jorge and Deininger, Michael W and Druker, Brian J
The Journal of clinical investigation, ISSN 0021-9738, 01/2011, Volume 121, Issue 1, pp. 396 - 409
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cell Survival - drug effects | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Drug Resistance, Neoplasm | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Neoplastic Stem Cells - metabolism | Models, Biological | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Fusion Proteins, bcr-abl - antagonists & inhibitors | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Benzamides | In Vitro Techniques | Cytokines - pharmacology | Stem cells | Physiological aspects | Genetic aspects | Research | Chronic myeloid leukemia | Drug therapy | Oncogenes | Index Medicus | Abridged Index Medicus
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3. Full Text Oncogenic CSF3R Mutations in Chronic Neutrophilic Leukemia and Atypical CML
by Maxson, Julia E and Gotlib, Jason and Pollyea, Daniel A and Fleischman, Angela G and Agarwal, Anupriya and Eide, Christopher A and Bottomly, Daniel and Wilmot, Beth and McWeeney, Shannon K and Tognon, Cristina E and Pond, J. Blake and Collins, Robert H and Goueli, Basem and Oh, Stephen T and Deininger, Michael W and Chang, Bill H and Loriaux, Marc M and Druker, Brian J and Tyner, Jeffrey W
The New England journal of medicine, ISSN 0028-4793, 05/2013, Volume 368, Issue 19, pp. 1781 - 1790
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | General aspects | Medical sciences | Leukemia, Neutrophilic, Chronic - diagnosis | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - diagnosis | Humans | Janus Kinases - antagonists & inhibitors | Animals | Receptors, Colony-Stimulating Factor - genetics | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Signal Transduction - physiology | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Leukemia, Neutrophilic, Chronic - genetics | Mutation | Leukemia, Lymphoid - genetics | Protein-Tyrosine Kinases - antagonists & inhibitors | Dasatinib | Care and treatment | Gene mutations | Causes of | Genetic aspects | Dosage and administration | Chronic myeloid leukemia | Diagnosis | Research | Drug therapy | Health aspects | Oncogenes | Tyrosine | BCR protein | Transformation | Myeloid leukemia | Colonies | Leukemia | Colleges & universities | Leukocytes (neutrophilic) | Patients | Lymphoma | Bone marrow | Janus kinase | Colony-stimulating factor | Protein-tyrosine kinase | Adapter proteins | Tumors | Index Medicus | Abridged Index Medicus
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4. Full Text Preferences for Immunotherapy in Melanoma: A Systematic Review
by Livingstone, Ann and Agarwal, Anupriya and Stockler, Martin R and Menzies, Alexander M and Howard, Kirsten and Morton, Rachael L
Annals of surgical oncology, ISSN 1068-9265, 02/2020, Volume 27, Issue 2, pp. 571 - 584
Oncology | Life Sciences & Biomedicine | Surgery | Science & Technology | Care and treatment | Immunotherapy | Ipilimumab | Melanoma | Interferon | Drug therapy | Biological response modifiers | Cancer | Index Medicus
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5. Full Text Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia
by Carey, Alyssa and Edwards, David K and Eide, Christopher A and Newell, Laura and Traer, Elie and Medeiros, Bruno C and Pollyea, Daniel A and Deininger, Michael W and Collins, Robert H and Tyner, Jeffrey W and Druker, Brian J and Bagby, Grover C and McWeeney, Shannon K and Agarwal, Anupriya
Cell reports (Cambridge), ISSN 2211-1247, 03/2017, Volume 18, Issue 13, pp. 3204 - 3218
AML | interleukin-1 | IL1R1 | bone marrow microenvironment | p38MAPK | functional screening | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Survival - drug effects | Interleukin-1 - metabolism | Tumor Stem Cell Assay | Leukemia, Myeloid, Acute - pathology | Humans | Leukemia, Myeloid, Acute - metabolism | Monocytes - metabolism | Disease Progression | Interleukin-1beta - blood | Receptors, Interleukin-1 - metabolism | Signal Transduction - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Interleukin-1beta - metabolism | Models, Biological | Bone Marrow - metabolism | Inflammation Mediators - metabolism | Cell Proliferation - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Bone Marrow - drug effects | Index Medicus | Interleukin-1 | Functional screening | Bone marrow microenvironment
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6. Full Text Simultaneous kinase inhibition with ibrutinib and BCL2 inhibition with venetoclax offers a therapeutic strategy for acute myeloid leukemia
by Eide, Christopher A and Kurtz, Stephen E and Kaempf, Andy and Long, Nicola and Agarwal, Anupriya and Tognon, Cristina E and Mori, Motomi and Druker, Brian J and Chang, Bill H and Danilov, Alexey V and Tyner, Jeffrey W
Leukemia, ISSN 0887-6924, 09/2020, Volume 34, Issue 9, pp. 2342 - 2353
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Pyrazoles - therapeutic use | Humans | Sulfonamides - pharmacology | Xenograft Model Antitumor Assays | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Sulfonamides - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Pyrimidines - therapeutic use | Cell Line, Tumor | Leukemia, Myeloid, Acute - drug therapy | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mice | Health aspects | Hematopoietic stem cells | Cell proliferation | Chronic lymphatic leukemia | Myeloid leukemia | Leukemia | Xenotransplantation | Clinical trials | Lymphatic leukemia | Kinases | Bruton's tyrosine kinase | Progenitor cells | Hemopoiesis | Cells (biology) | Interleukin 10 | Xenografts | Acute myeloid leukemia | Index Medicus
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7. Full Text Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia"
by Perrotti, Danilo and Agarwal, Anupriya and Lucas, Claire M and Narla, Goutham and Neviani, Paolo and Odero, Maria D and Ruvolo, Peter P and Verrills, Nicole M
Science translational medicine, ISSN 1946-6234, 07/2019, Volume 11, Issue 501, p. eaau0416
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Protein Kinase Inhibitors | Fusion Proteins, bcr-abl | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Drug Resistance, Neoplasm - drug effects | Tyrosine | BCR protein | Stem cells | Abl protein | Fusion protein | Protein-tyrosine kinase | Apoptosis | Index Medicus
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8. Full Text Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy
by Singer, Jack W and Fleischman, Angela and Al-Fayoumi, Suliman and Mascarenhas, John O and Yu, Qiang and Agarwal, Anupriya
Oncotarget, ISSN 1949-2553, 09/2018, Volume 9, Issue 70, pp. 33416 - 33439
Interleukin-1 receptor associated kinase (IRAK1) | Pacritinib | MyD88 | Inflammatory diseases | Cancer
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9. Full Text Pro-Inflammatory Pathways Drive Selective Advantage of Preleukemic Progenitors by Promoting Their Self-Renewal and Myeloid Differentiation
by Agarwal, Anupriya and Eden, Chris and Goldman, Devorah and Fleming, William
Experimental hematology, ISSN 0301-472X, 08/2018, Volume 64, pp. S53 - S54
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10. Full Text Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes
by Hosseini, Mona M and Kurtz, Stephen E and Abdelhamed, Sherif and Mahmood, Shawn and Davare, Monika A and Kaempf, Andy and Elferich, Johannes and McDermott, Jason E and Liu, Tao and Payne, Samuel H and Shinde, Ujwal and Rodland, Karin D and Mori, Motomi and Druker, Brian J and Singer, Jack W and Agarwal, Anupriya and Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Leukemia, ISSN 0887-6924, 11/2018, Volume 32, Issue 11, pp. 2374 - 2387
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Interleukin-1 Receptor-Associated Kinases - metabolism | Pyrazoles - therapeutic use | Humans | Leukemia, Myeloid, Acute - metabolism | Middle Aged | Male | Young Adult | Janus Kinase 2 - metabolism | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Child | Bridged-Ring Compounds - therapeutic use | Phenylurea Compounds - therapeutic use | Mice, SCID | Mutation - genetics | fms-Like Tyrosine Kinase 3 - metabolism | Xenograft Model Antitumor Assays | Animals | Mutation - drug effects | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Adolescent | Cell Line, Tumor | Mice, Inbred NOD | Aged | Benzothiazoles - therapeutic use | Mice | Chemotherapy | Usage | Interleukin-1 | Xenotransplantation | Nucleotide sequencing | Research | Gene expression | Health aspects | DNA sequencing | Cancer | Phosphorylation | Leukemia | Interleukin | Innate immunity | Kinases | Immunity | Genetic abnormalities | Janus kinase 2 | Interleukin 1 | Xenografts | Janus kinase | Inhibition | IRAK protein | Cell survival | Cytokines | Myeloid leukemia | Abnormalities | Inflammation | Survival | Inhibitors | Mutagenesis | Site-directed mutagenesis | Computer applications | Acute myeloid leukemia | Index Medicus | 60 APPLIED LIFE SCIENCES
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11. Full Text Marcks Is a Critical Downstream Mediator of IL-1-Driven AML Progression
by M.Hosseini, Mona and Lin, Hsin-Yun and Dewson, Gabby and Vivier, Ruthey and Agarwal, Anupriya
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2679 - 2679
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12. Full Text FGF2 from marrow microenvironment promotes resistance to FLT3 inhibitors in acute myeloid leukemia
by Traer, Elie and Martinez, Jacqueline and Javidi-Sharifi, Nathalie and Agarwal, Anupriya and Dunlap, Jennifer and English, Isabel and Kovacsovics, Tibor and Tyner, Jeffrey W and Wong, Melissa and Druker, Brian J
Cancer research (Chicago, Ill.), ISSN 0008-5472, 11/2016, Volume 76, Issue 22, pp. 6471 - 6482
Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Line, Tumor | Tumor Microenvironment | Fibroblast Growth Factor 2 - genetics | Humans | fms-Like Tyrosine Kinase 3 - metabolism | Leukemia, Myeloid, Acute - genetics | Index Medicus
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13. Full Text Differential regulation of microRNA-15a by radiation affects angiogenesis and tumor growth via modulation of acid sphingomyelinase
by Rana, Shushan and Espinosa-Diez, Cristina and Ruhl, Rebecca and Chatterjee, Namita and Hudson, Clayton and Fraile-Bethencourt, Eugenia and Agarwal, Anupriya and Khou, Sokchea and Thomas, Charles R and Anand, Sudarshan
Scientific reports, ISSN 2045-2322, 03/2020, Volume 10, Issue 1, pp. 5581 - 5581
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Human Umbilical Vein Endothelial Cells | Neoplasm Transplantation | Enzyme-Linked Immunosorbent Assay | Lung Neoplasms - mortality | HCT116 Cells | Humans | Lung Neoplasms - metabolism | MicroRNAs - radiation effects | MicroRNAs - metabolism | Ovarian Neoplasms - mortality | Blotting, Western | Breast Neoplasms - metabolism | Animals | Caspases - metabolism | Sphingomyelin Phosphodiesterase - metabolism | Breast Neoplasms - mortality | Female | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Ovarian Neoplasms - metabolism | Dose-Response Relationship, Radiation | Index Medicus
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