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Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2016, Volume 1470, pp. 85 - 94
RNAi-mediated screening has been an integral tool for biological discovery for the past 15 years. A variety of approaches have been employed for implementation... 
siRNA screening | Electroporation | Leukemia | Leukemia - pathology | RNA Interference | Electroporation - methods | Humans | Leukemia - genetics
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2013, Volume 368, Issue 19, pp. 1781 - 1790
Journal Article
Experimental Hematology, ISSN 0301-472X, 08/2018, Volume 64, pp. S53 - S54
Journal Article
Experimental Hematology, ISSN 0301-472X, 08/2018, Volume 64, pp. S53 - S54
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e106489
Cancer cachexia is a syndrome of weight loss that results from the selective depletion of skeletal muscle mass and contributes significantly to cancer... 
CANCER CACHEXIA | ACTIVATION | IMMUNE-SYSTEM | MULTIDISCIPLINARY SCIENCES | CARDIAC-HYPERTROPHY | IN-VIVO | FACTOR-KAPPA-B | NLRP3 INFLAMMASOME | ADRENAL AXIS | AUTOPHAGY | ATROGIN-1 | Neoplasms - metabolism | Receptors, Glucocorticoid - deficiency | Cachexia - chemically induced | Apoptosis - drug effects | Ubiquitin - metabolism | Male | Muscle, Skeletal - metabolism | Antineoplastic Agents - therapeutic use | Muscular Atrophy - chemically induced | Autophagy - drug effects | Lysosomes - metabolism | Antineoplastic Agents - adverse effects | Glucocorticoids - metabolism | Muscle, Skeletal - drug effects | Myocardium - metabolism | Female | Corticosterone - blood | Muscular Atrophy - metabolism | Muscular Atrophy - blood | Muscular Atrophy - pathology | Myocardium - pathology | Gene Knockout Techniques | Organ Specificity | Neoplasms - drug therapy | Organ Size - drug effects | Animals | Signal Transduction - drug effects | Receptors, Glucocorticoid - genetics | Mice | Muscle, Skeletal - pathology | Proteasome Endopeptidase Complex - metabolism | Neoplasms - pathology | Ubiquitin | Chemotherapy | Corticosterone | Muscles | Inflammation | Health aspects | Steroids | Cancer | Pediatrics | Glucocorticoids | Science | Cytotoxicity | Inflammatory response | Hypothalamus | Autophagy | Proteins | Atrophy | Rodents | Cytokines | Hypothalamic-pituitary-adrenal axis | Pharmacology | Cachexia | Morbidity | Skeletal muscle | Musculoskeletal system | Signaling | Pituitary | Laboratory animals | Phagocytosis
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2017, Volume 12, Issue 11, pp. e0188910 - e0188910
Protein phosphatase 2A (PP2A) is a ubiquitously expressed Serine-Threonine phosphatase mediating 30-50% of protein phosphatase activity. PP2A functions as a... 
Index Medicus
Journal Article
by Tyner, Jeffrey W and Tognon, Cristina E and Bottomly, Daniel and Wilmot, Beth and Kurtz, Stephen E and Savage, Samantha L and Long, Nicola and Schultz, Anna Reister and Traer, Elie and Abel, Melissa and Agarwal, Anupriya and Blucher, Aurora and Borate, Uma and Bryant, Jade and Burke, Russell and Carlos, Amy and Carpenter, Richie and Carroll, Joseph and Chang, Bill H and Coblentz, Cody and d’Almeida, Amanda and Cook, Rachel and Danilov, Alexey and Dao, Kim-Hien T and Degnin, Michie and Devine, Deirdre and Dibb, James and Edwards, David K and Eide, Christopher A and English, Isabel and Glover, Jason and Henson, Rachel and Ho, Hibery and Jemal, Abdusebur and Johnson, Kara and Johnson, Ryan and Junio, Brian and Kaempf, Andy and Leonard, Jessica and Lin, Chenwei and Liu, Selina Qiuying and Lo, Pierrette and Loriaux, Marc M and Luty, Samuel and Macey, Tara and MacManiman, Jason and Martinez, Jacqueline and Mori, Motomi and Nelson, Dylan and Nichols, Ceilidh and Peters, Jill and Ramsdill, Justin and Rofelty, Angela and Schuff, Robert and Searles, Robert and Segerdell, Erik and Smith, Rebecca L and Spurgeon, Stephen E and Sweeney, Tyler and Thapa, Aashis and Visser, Corinne and Wagner, Jake and Watanabe-Smith, Kevin and Werth, Kristen and Wolf, Joelle and White, Libbey and Yates, Amy and Zhang, Haijiao and Cogle, Christopher R and Collins, Robert H and Connolly, Denise C and Deininger, Michael W and Drusbosky, Leylah and Hourigan, Christopher S and Jordan, Craig T and Kropf, Patricia and Lin, Tara L and Martinez, Micaela E and Medeiros, Bruno C and Pallapati, Rachel R and Pollyea, Daniel A and Swords, Ronan T and Watts, Justin M and Weir, Scott J and Wiest, David L and Winters, Ryan M and McWeeney, Shannon K and Druker, Brian J
Nature, ISSN 0028-0836, 10/2018, Volume 562, Issue 7728, pp. 526 - 531
Journal Article
Cell Reports, ISSN 2211-1247, 03/2017, Volume 18, Issue 13, pp. 3204 - 3218
Journal Article
Reproductive BioMedicine Online, ISSN 1472-6483, 04/2019, Volume 38, pp. e29 - e30
Journal Article
Science Translational Medicine, ISSN 1946-6234, 07/2019, Volume 11, Issue 501, p. eaau0416
LB100 does not sensitize CML stem cells to tyrosine kinase inhibitor–induced apoptosis. 
Journal Article
Oncotarget, ISSN 1949-2553, 09/2018, Volume 9, Issue 70, pp. 33416 - 33439
Interleukin-1 receptor-associated kinases (IRAK1, IRAK2, IRAK3 [IRAK-M], and IRAK4) are serine-threonine kinases involved in toll-like receptor and... 
Interleukin-1 receptor associated kinase (IRAK1) | Pacritinib | MyD88 | Inflammatory diseases | Cancer
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 2726 - 2726
Abstract Background : Various pro-inflammatory and stress-related stimuli activate p38 mitogen-activated protein kinase (p38MAPK), triggering cascades of cell... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 329 - 329
Abstract Hematopoietic stem cells (HSCs) are a rare population in the bone marrow (BM) that mostly exists in a quiescent state. Upon environmental stresses... 
Journal Article