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Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7652, pp. 112 - 115
Protease-activated receptors ( PARs) are a family of G-proteincoupled receptors ( GPCRs) that are irreversibly activated by proteolytic cleavage of the N... 
PHENIX | THROMBIN | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | Allosteric Regulation - drug effects | Benzyl Alcohols - chemistry | Allosteric Site - drug effects | Humans | Receptor, PAR-2 - metabolism | Imidazoles - chemistry | Models, Molecular | Crystallography, X-Ray | Antibodies, Blocking - pharmacology | Imidazoles - pharmacology | Benzimidazoles - chemistry | Receptor, PAR-2 - chemistry | Immunoglobulin Fab Fragments - pharmacology | Receptor, PAR-2 - antagonists & inhibitors | Signal Transduction - drug effects | Antibodies, Blocking - chemistry | Immunoglobulin Fab Fragments - chemistry | Benzyl Alcohols - pharmacology | Benzimidazoles - pharmacology | Ligands | Benzodioxoles - chemistry | Kinetics | Benzodioxoles - pharmacology | Physiological aspects | Cell receptors | Allosteric proteins | Cytochrome | Residues | G protein-coupled receptors | Peptides | Molecular structure | Hydrogen | Homology | Antagonists | Hydrophobicity | Hydrogen bonding | Optimization | Proteins | Lipophilic | Allosteric properties | Imidazole | Cleavage | Inhibition | Thromboembolism | Lysozyme | Hydrogen ion concentration | Deoxyribonucleic acid--DNA | Cultivation | Architecture | Fab | Crystals | Crystallization | Pharmacology | Inflammation | Glycosylation | Computer programs | Chemistry | Diffraction | Antagonist drugs | Lysine | Isoforms | Computer applications | Mutation | Internet | Receptor mechanisms | Binding sites | Glutamine | Cancer
Journal Article
BioTechniques, ISSN 0736-6205, 08/2018, Volume 65, Issue 3, pp. 127 - 136
The benefits of polyclonal antibodies as tools for assay-specific target discovery and detection are numerous. As the future of basic research, diagnostics and... 
multi-antigen binding | antibodies | antibody comparisons | validation | polyclonal antibodies | THERAPEUTICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | FUTURE | CANCER-THERAPY | GENE | MONOCLONAL-ANTIBODIES | PROTEINS | Antibody Affinity | Reproducibility of Results | Binding Sites, Antibody | Research Design | Antibodies - chemistry
Journal Article
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1554, pp. 273 - 283
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 42 - 42
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/1999, Volume 274, Issue 48, p. 34233
Mutants with a cysteine residue in the γ subunit at position 207 and the ε subunit at position 31 were expressed in combination with a c -dimer construct,... 
Journal Article
PATHOLOGY, ISSN 0031-3025, 10/2014, Volume 46, Issue 6, pp. 509 - 517
The most common of all activating BRAF mutations (T1799A) leads to a substitution of valine (V) to glutamic acid (E) at the position 600 of the amino acid... 
PROTEIN | ASSAY | colon cancer | thyroid cancer | COLON | PATHOLOGY | IMMUNOHISTOCHEMICAL DETECTION | CANCER | BRAF V600E | MELANOMA | BRAF(V600E) MUTATION | DISEASE | immunohistochemistry | DNA sequencing
Journal Article
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