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Cell Cycle, ISSN 1538-4101, 06/2010, Volume 9, Issue 12, pp. 2423 - 2433
Loss of stromal caveolin 1 (Cav-1) is a novel biomarker for cancer-associated fibroblasts that predicts poor clinical outcome in breast cancer and DCIS... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Caveolin-1 | Lysosomal degradation | Chloroquine | Myofibroblast | Tumor stroma | TGFbeta signaling | Cancer associated fibroblasts | Autophagy | ACTIVATION | autophagy | TGF-BETA | lysosomal degradation | myofibroblast | SYSTEMIC-SCLEROSIS | cancer associated fibroblasts | CELL BIOLOGY | chloroquine | caveolin-1 | GROWTH | GENE-EXPRESSION | STROMAL FIBROBLASTS | VIMENTIN EXPRESSION | tumor stroma | TENASCIN | MMP-9 | PROGRESSION | Prognosis | Extracellular Matrix Proteins - biosynthesis | Coculture Techniques | Humans | Carcinoma, Intraductal, Noninfiltrating - metabolism | Transforming Growth Factor beta - biosynthesis | Autophagy - drug effects | Actins - genetics | Breast Neoplasms - metabolism | Chloroquine - pharmacology | Smad2 Protein - biosynthesis | Vimentin - genetics | Female | Microfilament Proteins - genetics | Fibroblasts - metabolism | Actins - biosynthesis | Calcium-Binding Proteins - biosynthesis | Vimentin - biosynthesis | Extracellular Matrix Proteins - genetics | Caveolin 1 - genetics | Caveolin 1 - metabolism | Microfilament Proteins - biosynthesis | Phenotype | Cell Line, Tumor | Biomarkers, Tumor - genetics | Transforming Growth Factor beta - metabolism | Biomarkers, Tumor - biosynthesis | Calcium-Binding Proteins - genetics
Journal Article
Cell Cycle, ISSN 1538-4101, 04/2012, Volume 11, Issue 7, pp. 1445 - 1454
We have recently proposed a new two-compartment model for understanding the Warburg effect in tumor metabolism. In this model, glycolytic stromal cells produce... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | complex IV | Report | mitochondria | OXPHOS | monocarboxylic acid transporter | TOMM20 | caveolin-1 | MCT4 | metastasis | inflammation | tumor stroma | two-compartment tumor metabolism | metabolic coupling | SLC16A3 | oxidative stress
Journal Article
Cell Cycle, ISSN 1538-4101, 03/2012, Volume 11, Issue 6, pp. 1108 - 1117
We have recently proposed a new model of cancer metabolism to explain the role of aerobic glycolysis and L-lactate production in fueling tumor growth and... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | caveolin-1 | lactate shuttle | MCT4 | Report | pseudohypoxia | monocarboxylic acid transporter | tumor stroma | predictive biomarker | two-compartment tumor metabolism | metabolic coupling | SLC16A3 | oxidative stress
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 01/2018, Volume 22, Issue 5, pp. 1185 - 1199
Approximately 30% of triple-negative breast cancers (TNBCs) exhibit functional loss of the RB tumor suppressor, suggesting a target for precision intervention.... 
cyclin | CHK1 | CDK4 | retinoblastoma | PLK1 | E2F | palbociclib | chemotherapy | ribociclib | CELL LUNG-CANCER | MODELS | SUBTYPES | PANCREATIC-CANCER | DNA-DAMAGE | CDK4/6 INHIBITION | S-PHASE PROGRESSION | THERAPEUTIC RESPONSE | RETINOBLASTOMA PATHWAY | TUMORIGENESIS | CELL BIOLOGY
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2010, Volume 9, Issue 10, pp. 1960 - 1971
Journal Article
Journal Article
Journal Article
Journal Article