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Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 5109 - 5109
Journal Article
International Journal of Cancer, ISSN 0020-7136, 06/2014, Volume 134, Issue 12, pp. 2798 - 2807
Aberrant glucose metabolism characterized by high levels of glycolysis, even in the presence of oxygen, is an important hallmark of cancer. This metabolic... 
HIF‐1α | metabolism | NF‐κB | drug resistance | metastasis | EMT | NF-κB | HIF-1α | COMPLEX | HIF-1 alpha | INDUCIBLE FACTOR-I | HYPOXIA | DEHYDROGENASE | BREAST-CANCER | NF-kappa B | GENE | ONCOLOGY | GROWTH | NF-KAPPA-B | TISSUE TRANSGLUTAMINASE | EXPRESSION | Up-Regulation | Epithelial Cells - metabolism | Humans | Gene Expression Regulation, Neoplastic | Transglutaminases - genetics | Mammary Glands, Human - metabolism | GTP-Binding Proteins - genetics | Promoter Regions, Genetic - genetics | Oxygen - metabolism | Breast Neoplasms - metabolism | Signal Transduction - immunology | Cell Respiration - genetics | MCF-7 Cells | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Lactic Acid - biosynthesis | Female | Hypoxia-Inducible Factor 1, alpha Subunit - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Down-Regulation | Transglutaminases - biosynthesis | Epithelial Cells - pathology | Mammary Glands, Human - pathology | Inflammation - immunology | Mitochondria - metabolism | Breast Neoplasms - genetics | Transcription Factor RelA - metabolism | Transcription Factor RelA - biosynthesis | Transglutaminases - metabolism | Cell Line, Tumor | Glucose - metabolism | Glycolysis | GTP-Binding Proteins - biosynthesis | RNA, Small Interfering | GTP-Binding Proteins - metabolism | Lactates | Glucose metabolism | Physiological aspects | Mitochondrial DNA | Glucose | Drug resistance | Dextrose | Rodents | Protein expression | Breast cancer | Metastasis | Metabolism | Cells | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e84627 - e84627
Homeostasis in eukaryotic tissues is tightly regulated by an intricate balance of the prosurvival and antisurvival signals. The tumor suppressor PTEN... 
POLY(ADP-RIBOSE) POLYMERASE | APOPTOSIS | CHEMOPREVENTIVE ACTION | CORN-OIL | MULTIDISCIPLINARY SCIENCES | RAT COLON | PROSTATE-CANCER | COLON CARCINOGENESIS | FATTY-ACIDS | UP-REGULATION | TRANSCRIPTION FACTOR | NF-kappa B p50 Subunit - metabolism | Rats, Wistar | Apoptosis - drug effects | PTEN Phosphohydrolase - metabolism | Rats | Male | Protein Transport - drug effects | Vascular Endothelial Growth Factor A - metabolism | Fish Oils - pharmacology | Corn Oil - pharmacology | Carcinogenesis - drug effects | Neoplasm Metastasis | Animals | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | Cell Proliferation - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Colorectal Neoplasms - pathology | Dietary Supplements | Immunohistochemistry | Regulators | Colorectal carcinoma | DNA damage | Colorectal cancer | Homeostasis | Homology | Kinases | ADP | Metastases | Ethylenediamine | Cell growth | Colon cancer | Ribose | Rodents | Animal tissues | Chromosome 10 | Cell cycle | Fish | Colon | Supplementation | Localization | Vascular endothelial growth factor | Deoxyribonucleic acid--DNA | Tensin | NF-κB protein | Receiving | Fish oils | Dietary supplements | Poly(ADP-ribose) polymerase | Inflammation | Augmentation | Polymerase | Signaling | Tumor suppressor genes | Fats and oils | Immunofluorescence | PTEN protein | Apoptosis | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Nutrition and Cancer, ISSN 0163-5581, 10/2016, Volume 68, Issue 7, pp. 1181 - 1191
Gut-associated immune response plays a major role in pathogenesis of many diseases including cancer. Modulation of intestinal immune response via dietary... 
Fish oils | Cytokines | Lymphocytes | Rodents | Colorectal cancer
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 01/2019, Volume 109, pp. 1462 - 1477
Colorectal cancer (CRC) is the most common carcinoma of the digestive tract. The slow growing nature of CRC offers a great opportunity for prevention... 
Cell proliferation | PI3K/Akt/mTOR signaling pathway | Piperlongumine | Colorectal cancer | Apoptosis | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | RAS | NATURAL-PRODUCTS | KINASE | CYCLE ARREST | GASTROINTESTINAL PHYSIOLOGY | COLORECTAL-CANCER | MYC | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | Proteins | Prevention | Alkaloids | Care and treatment | Colon cancer | Growth | Analysis | Liver | Tumors | Cancer | Index Medicus
Journal Article
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 04/2016, Volume 79, p. 9
Resistance in apoptosis by disruption in signaling pathways is a common trait in malignancy. Celecoxib, a specific COX-2 inhibitor, has been reported to exert... 
Prevention | COX-2 inhibitors | Celecoxib | Angiogenesis inhibitors | Carcinogenesis | Cancer | Apoptosis | Proteins | Nonsteroidal anti-inflammatory drugs
Journal Article
Tumor Biology, ISSN 1010-4283, 3/2017, Volume 39, Issue 3, pp. 1010428317695019 - 1010428317695019
5-Fluorouracil has been considered as a cornerstone therapy for colorectal cancer; however, it suffers from low therapeutic response rate and severe side... 
5-fluorouracil | apoptosis | colorectal cancer | Fish oil | n-3 polyunsaturated fatty acids | MITOCHONDRIA | DEATH | DRUG-RESISTANCE | PLASMA-MEMBRANE | BREAST-CANCER CELLS | CARCINOGENESIS | ONCOLOGY | COLORECTAL-CANCER | MEMBRANE-FLUIDITY | POLYUNSATURATED FATTY-ACIDS | UP-REGULATION | Colonic Neoplasms - genetics | Apoptosis - drug effects | Colonic Neoplasms - drug therapy | Humans | Colonic Neoplasms - chemically induced | Neoplasms, Experimental - chemically induced | Neoplasms, Experimental - pathology | Fluorouracil - administration & dosage | Neoplasms, Experimental - genetics | Fish Oils - administration & dosage | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma - pathology | Carcinoma - drug therapy | DNA Damage - drug effects | Neoplasm Proteins - biosynthesis | Carcinoma - chemically induced | Dextran Sulfate - toxicity | Drug Synergism | Animals | Colonic Neoplasms - pathology | Carcinoma - genetics | Cell Proliferation - drug effects | Mice | Methylhistamines - toxicity | Neoplasms, Experimental - drug therapy | Drug Resistance, Neoplasm - drug effects | Cytochrome | Bax protein | Bcl-2 protein | 5-Fluorouracil | Polyunsaturated fatty acids | DNA damage | Colorectal carcinoma | Colorectal cancer | Science | Chemosensitization | Cancer therapies | Membrane fluidity | Cell growth | Colon cancer | Fluidity | Dextran sulfate | Supplementation | Colon | Drug dosages | Deoxyribonucleic acid--DNA | Fish oils | Tumor cells | Caspase | Fatty acids | Dextran | Caspase-8 | Hypotheses | FasL protein | Sodium | Ligands | Tumors | Apoptosis | Index Medicus
Journal Article
BioMed Research International, ISSN 2314-6133, 01/2014, Volume 2014
  Ceramide mediates inhibition of cyclooxygenase-2 (COX-2) which catalyzes formation of prostaglandin further activating peroxisome proliferator-activated... 
Fish oils | Kinases | Fatty acids | Rodents | Colorectal cancer
Journal Article
Microchimica Acta, ISSN 0026-3672, 3/2019, Volume 186, Issue 3, pp. 1 - 11
An electrochemical hybridization assay is described for the determination of microRNA-21. Fluorine tin oxide (FTO) sheets were coated with carboxylated... 
Chemistry | Analytical Chemistry | Gene assay | Microengineering | Characterization and Evaluation of Materials | Electrochemical biosensor | MicroRNA-21 | Au-PtBNPs | Nanochemistry | Breast Cancer | Nanotechnology | BREAST-CANCER | CHEMISTRY, ANALYTICAL | MIRNA | LABEL | NANOCOMPOSITE | Nanoparticles | MicroRNA | Graphene | Analysis | Graphite | Electrochemistry | Biotin | Fluorides | Sensors | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 06/2014, Volume 134, Issue 12, pp. 2798 - 2807
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 02/2018, Volume 98, pp. 600 - 608
Intraepithelial lymphocytes (IELs) impart a crucial role in maintaining intestinal homeostasis, yet their role in colon cancer pathogenesis remains unknown.... 
Intraepithelial lymphocytes | n-3 PUFAs | Colon cancer | Dendritic cells | DMH | Cytotoxic T cells | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | IFN-GAMMA | LACTOBACILLI | MATURATION | INTERFERON-GAMMA | IMMUNOTHERAPY | COLORECTAL-CANCER | PHARMACOLOGY & PHARMACY | FISH-OIL | GRANZYME-B | PROGRESSION | Index Medicus
Journal Article
2017
This doctoral research focuses on the exploration of the working lives of ‘management consultants’ with an emphasis on how consultants make sense of, interact... 
Dissertation
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 10/2019, Volume 1864, Issue 10, pp. 1314 - 1327
Accumulation of cholesterol is a well-known feature in cancer. Preclinical studies suggest the contribution of various cholesterol regulators in CRC. However,... 
HMGCR | Liver X receptors | LDLR | SREBF2 | Cholesterol efflux | SURVIVAL | CELLS | PROGNOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | BREAST-CANCER | BIOPHYSICS | GROWTH | 27-HYDROXYCHOLESTEROL | EXPRESSION | Deregulation | RNA | Liver | Genes | Colorectal cancer | Homeostasis | Genetic research | Genetic aspects | Metastasis | Cholesterol | Cancer | Index Medicus
Journal Article
Tumor Biology, ISSN 1010-4283, 12/2013, Volume 34, Issue 6, pp. 3753 - 3764
Cyclooxygenase (COX)-2 inhibition by nonsteroidal anti-inflammatory drugs is a useful approach for cancer prevention but has several side effects. A novel... 
Breast cancer | c-myc | Redox signaling | Cell cycle | Apoptosis | OXIDATIVE STRESS | INCREASED EXPRESSION | BETA-CATENIN | BREAST-CANCER | COLON-CANCER | PROGNOSTIC-FACTOR | EPITHELIAL-CELLS | ONCOLOGY | C-MYC AMPLIFICATION | POLYUNSATURATED FATTY-ACIDS | CYCLOOXYGENASE-2 INHIBITOR | Immunohistochemistry | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Rats, Wistar | Apoptosis - drug effects | Calcium - metabolism | Epithelial Cells - drug effects | Mammary Neoplasms, Experimental - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Flow Cytometry | Fatty Acids, Omega-3 - pharmacology | Female | Fish Oils - administration & dosage | Epithelial Cells - cytology | Fatty Acids, Omega-3 - administration & dosage | Pyrazoles - pharmacology | Mammary Neoplasms, Experimental - prevention & control | Cyclooxygenase 2 Inhibitors - pharmacology | Cyclooxygenase 2 Inhibitors - administration & dosage | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Rats | Celecoxib | Fish Oils - pharmacology | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-myc - metabolism | Mammary Glands, Animal - cytology | Mammary Neoplasms, Experimental - chemically induced | Pyrazoles - administration & dosage | Animals | 9,10-Dimethyl-1,2-benzanthracene | Cell Cycle - drug effects | Keratin-19 - metabolism | Fish Oils - chemistry | Sulfonamides - administration & dosage | COX-2 inhibitors | Unsaturated fatty acids | Analysis | Benzene | Xylene | Dietary fat | Nonsteroidal anti-inflammatory drugs | Tumor proteins | Carcinogenesis | Preventive medicine | Fish oils | Cellular biology | Rodents | Index Medicus
Journal Article