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1. Full Text MicroRNAs (miRNAs) in cancer invasion and metastasis: therapeutic approaches based on metastasis-related miRNAs
by Aigner, Achim
Journal of molecular medicine (Berlin, Germany), ISSN 0946-2716, 5/2011, Volume 89, Issue 5, pp. 445 - 457
Human Genetics | Biomedicine | MicroRNAs | Novel miRNA-based therapies | Internal Medicine | miRNA | Molecular Medicine | Metastasis | Genetics & Heredity | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Neoplasm Metastasis - genetics | Neoplasms - therapy | MicroRNAs - genetics | Neoplasms - genetics | Neoplasms - pathology | Humans | Care and treatment | MicroRNA | Physiological aspects | Genetic aspects | Research | Gene therapy | Health aspects | Index Medicus
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2. Perspectives, issues and solutions in RNAi therapy: the expected and the less expected
by Aigner, Achim
Nanomedicine (London, England), 11/2019, Volume 14, Issue 21, pp. 2777 - 2782
Nanocapsules - administration & dosage | Humans | Amyloid Neuropathies, Familial - therapy | Molecular Targeted Therapy | Nanocapsules - chemistry | Chemistry, Pharmaceutical | RNAi Therapeutics - methods | Gene Knockdown Techniques | Animals | Biological Transport | RNA Interference | Genetic Vectors | Genome | RNA, Small Interfering - metabolism | Index Medicus
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3. Full Text Applications of RNA interference: current state and prospects for siRNA-based strategies in vivo
by Aigner, Achim
Applied microbiology and biotechnology, ISSN 0175-7598, 8/2007, Volume 76, Issue 1, pp. 9 - 21
Biotechnology | Chemistry | RNAi | Nanoplexes | RNA interference | Microbiology | Microbial Genetics and Genomics | Gene-targeting | siRNA | Nonviral siRNA delivery | Gene knockdown | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Gene Targeting | RNA, Small Interfering - genetics | Neoplasms - therapy | Animals | RNA Interference | RNA, Small Interfering - therapeutic use | Humans | Gene Silencing | Virus Diseases - therapy | Clinical Trials as Topic | Chemistry, Pharmaceutical | Nanoparticles | Ribonucleic acid--RNA | Medical treatment | Index Medicus | Mini-Review
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4. Full Text Gene silencing through RNA interference (RNAi) in vivo: Strategies based on the direct application of siRNAs
by Aigner, Achim
Journal of biotechnology, ISSN 0168-1656, 2006, Volume 124, Issue 1, pp. 12 - 25
RNAi | Polyethylenimine | Gene-silencing | In vivo siRNA delivery | PEI | siRNAs | RNA, Small Interfering - chemistry | RNA, Small Interfering - genetics | Polyethyleneimine - metabolism | RNA Interference | Polyethyleneimine - administration & dosage | Polyethyleneimine - chemistry | Gene Silencing | RNA, Small Interfering - administration & dosage | RNA, Small Interfering - metabolism | Fluorescence | Genetic engineering | Messenger RNA | Epidermal growth factor | Health aspects | Index Medicus
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5. MicroRNAs (miRNAs) in colorectal cancer: From aberrant expression towards therapy
by Dassow, Hannelore and Aigner, Achim
Current pharmaceutical design, ISSN 1381-6128, 2013, Volume 19, Issue 7, pp. 1242 - 1252
Nanoparticles | RNA delivery | MiRNA replacement | Novel miRNA-based therapies | Colorectal cancer | AntimiRs | MiRNAs | Anticancer therapy | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Colorectal Neoplasms - therapy | Gene Expression | Models, Biological | Colorectal Neoplasms - genetics | Humans | MicroRNAs - genetics | Colorectal Neoplasms - diagnosis | Drugs | Angiogenesis | Chemotherapy | Molecular modelling | Reviews | RNA | Therapeutic applications | miRNA | Tumorigenesis | Metastases
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6. Nanoparticle/siRNA-based therapy strategies in glioma: Which nanoparticles, which siRNAs?
by Aigner, Achim and Kögel, Donat
Nanomedicine (London, England), ISSN 1743-5889, 01/2018, Volume 13, Issue 1, pp. 89 - 103
target gene knockdown | siRNA delivery | glioma | preclinical mouse glioma models | RNAi | nanoparticles | Science & Technology - Other Topics | Nanoscience & Nanotechnology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Index Medicus
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7. Full Text A Poly(Propyleneimine) Dendrimer‐Based Polyplex‐System for Single‐Chain Antibody‐Mediated Targeted Delivery and Cellular Uptake of SiRNA
by Tietze, Stefanie and Schau, Isabell and Michen, Susanne and Ennen, Franka and Janke, Andreas and Schackert, Gabriele and Aigner, Achim and Appelhans, Dietmar and Temme, Achim
Small (Weinheim an der Bergstrasse, Germany), ISSN 1613-6810, 07/2017, Volume 13, Issue 27, pp. 1700072 - n/a
targeted delivery | siRNA | single chain antibodies | poly(propyleneimine) | polyplexes | RNA, Small Interfering - chemistry | Nanoparticles - chemistry | Humans | Cell Line, Tumor | Dendrimers - chemistry | Polypropylenes - chemistry | Endocytosis - genetics | Single-Chain Antibodies - chemistry | Endocytosis - physiology | Viral antibodies | Antibodies | Dendrimers | Metastasis | Sugars | Excretion | Modular systems | Organs | Chains | Pharmacology | Biotin | Maltose | Fragmentation | Carriers | Nanoparticles | Side effects | Barriers | Strategy | Ligands | Tumors | Cancer | Index Medicus
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8. Full Text The Special AT-rich Sequence Binding Protein 1 (SATB1) and its role in solid tumors
by Frömberg, Anja and Engeland, Kurt and Aigner, Achim
Cancer letters, ISSN 0304-3835, 03/2018, Volume 417, pp. 96 - 111
Mamma carcinoma | Chromatin | Glioma | SATB1 | Colorectal carcinoma | Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | Cell Cycle - genetics | Cell Proliferation - genetics | Matrix Attachment Region Binding Proteins - metabolism | Humans | Carcinogenesis - genetics | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Epithelial-Mesenchymal Transition - genetics | Carcinogenesis - metabolism | Neoplasm Metastasis | Neoplasms - genetics | Matrix Attachment Region Binding Proteins - genetics | Neoplasms - pathology | Gliomas | Oncology, Experimental | Colorectal cancer | Development and progression | Metastasis | Research | Genetic transcription | Drug resistance | Cancer | Protein binding | Index Medicus
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