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by Wray, Naomi R and Ripke, Stephan and Mattheisen, Manuel and Trzaskowski, MacIej and Byrne, Enda M and Abdellaoui, Abdel and Adams, Mark J and Agerbo, Esben and Air, Tracy M and Andlauer, Till M. F and Bacanu, Silviu-Alin and Bækvad-Hansen, Marie and Beekman, Aartjan F. T and Bigdeli, Tim B and Binder, Elisabeth B and Blackwood, Douglas R. H and Bryois, Julien and Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and Cai, Na and Castelao, Enrique and Christensen, Jane Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan I. R and Colodro-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Crowley, Cheynna A and Dashti, Hassan S and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and DIrek, Nese and Dolan, Conor V and Dunn, Erin C and Eley, Thalia C and Eriksson, Nicholas and Escott-Price, Valentina and Kiadeh, Farnush Hassan Farhadi and Finucane, Hilary K and Forstner, Andreas J and Frank, Josef and Gaspar, Héléna A and Gill, Michael and Giusti-Rodríguez, Paola and Goes, Fernando S and Gordon, Scott D and Grove, Jakob and Hall, Lynsey S and Hannon, Eilis and Hansen, Christine Søholm and Hansen, Thomas F and Herms, Stefan and Hickie, Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten and Hottenga, Jouke-Jan and Hougaard, David M and Hu, Ming and Hyde, Craig L and Ising, Marcus and Jansen, Rick and Jin, Fulai and Jorgenson, Eric and Knowles, James A and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren W and Krogh, Jesper and Kutalik, Zoltán and Lane, Jacqueline M and Li, Yihan and Li, Yun and Lind, Penelope A and Liu, Xiaoxiao and Lu, Leina and MacIntyre, Donald J and MacKinnon, Dean F and Maier, Robert M and Maier, Wolfgang and Marchini, Jonathan and Mbarek, Hamdi and McGrath, Patrick and McGuffin, Peter and Medland, Sarah E and Mehta, DIvya and Middeldorp, Christel M and Mihailov, Evelin and Milaneschi, Yuri and Milani, Lili and Mill, Jonathan and Mondimore, Francis M and Montgomery, Grant W and Mostafavi, Sara and Mullins, Niamh and Nauck, Matthias and Ng, Bernard and ... and Major Depressive Disorder Working and EQTLGEN and eQTLGen and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and 23andMe and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Nature Genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 668 - 681
Journal Article
by Culverhouse, R.C and Saccone, N.L and Horton, A.C and Ma, Y and Anstey, K.J and Banaschewski, T and Burmeister, M and Cohen-Woods, S and Etain, B and Fisher, H.L and Goldman, N and Guillaume, S and Horwood, J and Juhasz, G and Lester, K.J and Mandelli, L and Middeldorp, C.M and Olié, E and Villafuerte, S and Air, T.M and Araya, R and Bowes, L and Burns, R and Byrne, E.M and Coffey, C and Coventry, W.L and Gawronski, K.A.B and Glei, D and Hatzimanolis, A and Hottenga, J.-J and Jaussent, I and Jawahar, C and Jennen-Steinmetz, C and Kramer, J.R and Lajnef, M and Little, K and Zu Schwabedissen, H.M and Nauck, M and Nederhof, E and Petschner, P and Peyrot, W.J and Schwahn, C and Sinnamon, G and Stacey, D and Tian, Y and Toben, C and Van Der Auwera, S and Wainwright, N and Wang, J.-C and Willemsen, G and Anderson, I.M and Arolt, V and Aslund, C and Bagdy, G and Baune, B.T and Bellivier, F and Boomsma, D.I and Courtet, P and Dannlowski, U and De Geus, E.J.C and Deakin, J.F.W and Easteal, S and Eley, T and Fergusson, D.M and Goate, A.M and Gonda, X and Grabe, H.J and Holzman, C and Johnson, E.O and Kennedy, M and Laucht, M and Martin, N.G and Munafò, M.R and Nilsson, K.W and Oldehinkel, A.J and Olsson, C.A and Ormel, J and Otte, C and Patton, G.C and Penninx, B.W.J.H and Ritchie, K and Sarchiapone, M and Scheid, J.M and Serretti, A and Smit, J.H and Stefanis, N.C and Surtees, P.G and Völzke, H and Weinstein, M and Whooley, M and Nurnberger, J.I and Breslau, N and Bierut, L.J and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Centrum för klinisk forskning, Västerås
Molecular Psychiatry, ISSN 1359-4184, 01/2018, Volume 23, Issue 1, pp. 133 - 142
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with increased risk of depression, but only in individuals... 
COHORT PROFILE | CHILDHOOD MALTREATMENT | ENVIRONMENT INTERACTION | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | RISK | MAJOR DEPRESSION | SEROTONIN TRANSPORTER GENE | NEUROSCIENCES | SAMPLE | POLYMORPHISM 5-HTTLPR | DISORDER | LIFE EVENTS | Stress, Psychological - genetics | Genetic Predisposition to Disease | Serotonin Plasma Membrane Transport Proteins - genetics | Humans | Life Change Events | Cooperative Behavior | Depression - psychology | Genotype | Depression - genetics | Gene-Environment Interaction | Stress, Psychological - complications | Genetic aspects | Research | Depression, Mental | Risk factors | Data analysis | Statistical analysis | Serotonin | Data processing | Mental depression | Subgroups | Strong interactions (field theory) | Consortia | Genotype & phenotype | Hypotheses | Serotonin transporter | Alleles | Children | Transporter | Genotypes | Index Medicus | Neurologi | Basic Medicine | Biological Sciences | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Hälsovetenskaper | Klinisk medicin | Clinical Medicine | Neurology | Occupational Health and Environmental Health | Naturvetenskap | Biokemi och molekylärbiologi | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Arbetsmedicin och miljömedicin | Psykiatri | Biochemistry and Molecular Biology | Natural Sciences | Psychiatry | Health Sciences | Neurovetenskaper
Journal Article
by Grove, Jakob and Ripke, Stephan and Als, Thomas D and Mattheisen, Manuel and Walters, Raymond K and Won, Hyejung and Pallesen, Jonatan and Agerbo, Esben and Andreassen, Ole A and Anney, Richard and Awashti, Swapnil and Belliveau, Rich and Bettella, Francesco and Buxbaum, Joseph D and Bybjerg-Grauholm, Jonas and Bækvad-Hansen, Marie and Cerrato, Felecia and Chambert, Kimberly and Christensen, Jane H and Churchhouse, Claire and Dellenvall, Karin and Demontis, Ditte and De Rubeis, Silvia and Devlin, Bernie and Djurovic, Srdjan and Dumont, Ashley L and Goldstein, Jacqueline I and Hansen, Christine S and Hauberg, Mads Engel and Hollegaard, Mads V and Hope, Sigrun and Howrigan, Daniel P and Huang, Hailiang and Hultman, Christina M and Klei, Lambertus and Maller, Julian and Martin, Joanna and Martin, Alicia R and Moran, Jennifer L and Nyegaard, Mette and Nærland, Terje and Palmer, Duncan S and Palotie, Aarno and Pedersen, Carsten Bøcker and Pedersen, Marianne Giørtz and dPoterba, Timothy and Poulsen, Jesper Buchhave and Pourcain, Beate St and Qvist, Per and Rehnström, Karola and Reichenberg, Abraham and Reichert, Jennifer and Robinson, Elise B and Roeder, Kathryn and Roussos, Panos and Saemundsen, Evald and Sandin, Sven and Satterstrom, F. Kyle and Davey Smith, George and Stefansson, Hreinn and Steinberg, Stacy and Stevens, Christine R and Sullivan, Patrick F and Turley, Patrick and Walters, G. Bragi and Xu, Xinyi and Wray, Naomi R and Trzaskowski, Maciej and Byrne, Enda M and Abdellaoui, Abdel and Adams, Mark J and Air, Tracy M and Andlauer, Till F. M and Bacanu, Silviu-Alin and Beekman, Aartjan T. F and Bigdeli, Tim B and Binder, Elisabeth B and Blackwood, Douglas H. R and Bryois, Julien and Buttenschøn, Henriette N and Cai, Na and Castelao, Enrique and Clarke, Toni-Kim and Coleman, Jonathan R. I and Colodro-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and Direk, Nese and Dolan, Conor V and Dunn, Erin C and Eley, Thalia C and Escott-Price, Valentina and Kiadeh, Farnush Farhadi Hassan and Finucane, Hilary K and Forstner, Andreas J and ... and Psychiat Genomics Consortium and BUPGEN and 23andMe Res Team and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and 23andMe Research Team and Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium
Nature Genetics, ISSN 1061-4036, 2019, Volume 51, Issue 3, pp. 431 - 431
Journal Article
by Peyrot, Wouter J and Van der Auwera, Sandra and Milaneschi, Yuri and Dolan, Conor V and Madden, Pamela A.F and Sullivan, Patrick F and Strohmaier, Jana and Ripke, Stephan and Rietschel, Marcella and Nivard, Michel G and Mullins, Niamh and Montgomery, Grant W and Henders, Anjali K and Heat, Andrew C and Fisher, Helen L and Dunn, Erin C and Byrne, Enda M and Air, Tracy A and Air, Tracy M and Wray, Naomi R and Mattheisen, Manuel and Trzaskowski, Maciej and Abdellaoui, Abdel and Adams, Mark J and Agerbo, Esben and Andlauer, Till F.M and Bacanu, Silviu-Alin and Bækvad-Hansen, Marie and Beekman, Aartjan T.F and Bigdeli, Tim B and Binder, Elisabeth B and Blackwood, Douglas H.R and Bryois, Julien and Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and Cai, Na and Castelao, Enrique and Christensen, Jane Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan R.I and Colodro-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and Direk, Nese and Eley, Thalia C and Escott-Price, Valentina and Farnush and Kiadeh, Farhadi Hassan and Finucane, Hilary K and Forstner, Andreas J and Frank, Josef and Gaspar, Héléna A and Gill, Michael and Goes, Fernando S and Gordon, Scott D and Grove, Jakob and Hall, Lynsey S and Hansen, Christine Søholm and Hansen, Thomas F and Herms, Stefan and Hicki, Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten and Hottenga, Jouke-Jan and Hougaard, David M and Ising, Marcus and Jansen, Rick and Jorgenson, Eric and Knowles, James A and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren W and Krogh, Jesper and Kutalik, Zoltán and Li, Yihan and Li, Qingqin S and Lind, Penelope A and MacIntyre, Donald J and MacKinnon, Dean F and Maier, Wolfgang and Maier, Robert M and Marchini, Jonathan and Mbarek, Hamdi and McGrath, Patrick and McGuffin, Peter and Medland, Sarah E and Mehta, Divya and Middeldorp, Christel M and Mihailov, Evelin and Milani, Lili and Mondimore, Francis M and Mostafavi, Sara and Nauck, Matthias and Ng, Bernard and ... and Disorder Working Grp Psychiatric G and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Biological Psychiatry, ISSN 0006-3223, 07/2018, Volume 84, Issue 2, pp. 138 - 147
The heterogeneity of genetic effects on major depressive disorder (MDD) may be partly attributable to moderation of genetic effects by environment, such as... 
Depression | Genetics | Polygenic risk | Childhood trauma | Interaction | Meta-analysis | 5-HTTLPR | VARIANTS | PSYCHIATRY | DISORDERS | LOCI | MAJOR DEPRESSION | NEUROSCIENCES | GENE-ENVIRONMENT INTERACTION | LIFE STRESS | QUESTIONNAIRE | ASSOCIATION | PSYCHOPATHOLOGY | Psychological aspects | Depression, Mental | Genetic research | Genetic aspects | Psychic trauma | Child psychopathology | Risk factors
Journal Article
by Mullins, Niamh and Bigdeli, Tim B and Børglum, Anders D and Coleman, Jonathan R.I and Demontis, Ditte and Mehta, Divya and Power, Robert A and Ripke, Stephan and Stahl, Eli A and Starnawska, Anna and Anjorin, Adebayo and Corvin, Aiden and Sanders, Alan R and Forstner, Andreas J and Reif, Andreas and Koller, Anna C and Świątkowska, Beata and Baune, Bernhard T and Müller-Myhsok, Bertram and Penninx, Brenda W.J.H and Pato, Carlos and Zai, Clement and Rujescu, Dan and Hougaard, David M and Quested, Digby and Levinson, Douglas F and Binder, Elisabeth B and Byrne, Enda M and Agerbo, Esben and Streit, Fabian and Mayoral, Fermin and Bellivier, Frank and Degenhardt, Franziska and Breen, Gerome and Morken, Gunnar and Turecki, Gustavo and Rouleau, Guy A and Grabe, Hans J and Völzke, Henry and Jones, Ian and Giegling, Ina and Agartz, Ingrid and Melle, Ingrid and Lawrence, Jacob and Walters, James T.R and Strohmaier, Jana and Shi, Jianxin and Hauser, Joanna and Biernacka, Joanna M and Vincent, John B and Kelsoe, John and Strauss, John S and Lissowska, Jolanta and Pimm, Jonathan and Smoller, Jordan W and Guzman-Parra, José and Berger, Klaus and Scott, Laura J and Jones, Lisa A and Azevedo, M. Helena and Trzaskowski, Maciej and Kogevinas, Manolis and Rietschel, Marcella and Boks, Marco and Ising, Marcus and Grigoroiu-Serbanescu, Maria and Hamshere, Marian L and Leboyer, Marion and Frye, Mark and Nöthen, Markus M and Alda, Martin and Preisig, Martin and Nordentoft, Merete and Boehnke, Michael and O’Donovan, Michael C and Owen, Michael J and Pato, Michele T and Renteria, Miguel E and Budde, Monika and Weissman, Myrna M and Wray, Naomi R and Bass, Nicholas and Craddock, Nicholas and Smeland, Olav B and Andreassen, Ole A and Mors, Ole and Gejman, Pablo V and Sklar, Pamela and McGrath, Patrick and Hoffmann, Per and McGuffin, Peter and Lee, Phil H and Mortensen, Preben Bo and Kahn, René S and Ophoff, Roel A and Adolfsson, Rolf and Van der Auwera, Sandra and Djurovic, Srdjan and Kloiber, Stefan and Heilmann-Heimbach, Stefanie and ... and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium and Dipl.-Psych and M.R.C.Psych and Dr.Med.Sc and Bipolar Disorder Working Group of the Psychiatric Genomics Consortium and Schizophrenia Working Group of the Psychiatric Genomics Consortium
American Journal of Psychiatry, ISSN 0002-953X, 08/2019, Volume 176, Issue 8, pp. 651 - 660
Objective:More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of... 
Genetics | Bipolar disorder | Mental disorders | Etiology | Suicides & suicide attempts | Index Medicus | Abridged Index Medicus
Journal Article
by Czamara, Darina and Eraslan, Gökçen and Page, Christian M and Lahti, Jari and Lahti-Pulkkinen, Marius and Hämäläinen, Esa and Kajantie, Eero and Laivuori, Hannele and Villa, Pia M and Reynolds, Rebecca M and Nystad, Wenche and Håberg, Siri E and London, Stephanie J and O’Donnell, Kieran J and Garg, Elika and Meaney, Michael J and Entringer, Sonja and Wadhwa, Pathik D and Buss, Claudia and Jones, Meaghan J and Lin, David T. S and MacIsaac, Julie L and Kobor, Michael S and Koen, Nastassja and Zar, Heather J and Koenen, Karestan C and Dalvie, Shareefa and Stein, Dan J and Kondofersky, Ivan and Müller, Nikola S and Theis, Fabian J and Wray, Naomi R and Ripke, Stephan and Mattheisen, Manuel and Trzaskowski, Maciej and Byrne, Enda M and Abdellaoui, Abdel and Adams, Mark J and Agerbo, Esben and Air, Tracy M and Andlauer, Till F. M and Bacanu, Silviu-Alin and Bækvad-Hansen, Marie and Beekman, Aartjan T. F and Bigdeli, Tim B and Blackwood, Douglas H. R and Bryois, Julien and Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and Cai, Na and Castelao, Enrique and Christensen, Jane Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan R. I and Colodro-Conde, Lucía and Couvy-Duchesne, Baptiste and Craddock, Nick and Crawford, Gregory E and Davies, Gail and Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and Direk, Nese and Dolan, Conor V and Dunn, Erin C and Eley, Thalia C and Escott-Price, Valentina and Kiadeh, Farnush Farhadi Hassan and Finucane, Hilary K and Forstner, Andreas J and Frank, Josef and Gaspar, Héléna A and Gill, Michael and Goes, Fernando S and Gordon, Scott D and Grove, Jakob and Hall, Lynsey S and Hansen, Christine Søholm and Hansen, Thomas F and Herms, Stefan and Hickie, Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten and Hottenga, Jouke-Jan and Hougaard, David M and Ising, Marcus and Jansen, Rick and Jorgenson, Eric and Knowles, James A and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren W and Krogh, Jesper and Kutalik, Zoltán and Li, Yihan and Lind, Penelope A and MacIntyre, Donald J and MacKinnon, Dean F and Maier, Robert M and ... and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2548 - 18
Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms allowing integration of genetic and environmental factors to shape cellular... 
Epigenesis, Genetic | Humans | Risk Factors | Genotype | Male | DNA Methylation - genetics | Gene-Environment Interaction | DNA - blood | Pregnancy | Female | Fetal Blood | Infant, Newborn | Cohort Studies | Neonates | Genetic variance | Cord blood | Genetic analysis | Health risks | DNA methylation | Environmental factors | Methylation | Blood | Environmental effects | Genotypes | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article