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CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2019, Volume 25, Issue 15, pp. 4586 - 4588
Multitarget assays have become common in clinical molecular diagnostic laboratories. However, all assays, no matter how well designed, have inherent gaps due... 
ONCOLOGY
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 08/2015, Volume 10, Issue 8, pp. 1129 - 1130
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 06/2018, Volume 142, Issue 6, pp. 684 - 685
The number of proven and investigational targeted therapies associated with specific genomic or other alterations is ever-growing, leaving challenges for... 
MEDICINE, RESEARCH & EXPERIMENTAL | CYTOLOGY SPECIMENS | SAMPLES | MEDICAL LABORATORY TECHNOLOGY | PATHOLOGY | CANCER | EGFR | Pathology | Cellular biology | Precision medicine | Laboratories | Biopsy | Lung cancer | Non-small cell lung carcinoma | Cytopathology | Mutation | Patients | Tumors
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2015, Volume 372, Issue 18, pp. 1700 - 1709
Patients with non–small-cell lung cancer and mutated epidermal growth factor receptors who develop resistance to EGFR inhibitors through a particular mutation... 
TYROSINE KINASE INHIBITORS | MEDICINE, GENERAL & INTERNAL | PHASE-II TRIAL | GEFITINIB | ADENOCARCINOMA | ACQUIRED-RESISTANCE | MUTATIONS | AFATINIB | ERLOTINIB | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Acrylamides - pharmacokinetics | Dose-Response Relationship, Drug | Hyperglycemia - chemically induced | Antineoplastic Agents - adverse effects | Female | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Protein Kinase Inhibitors - pharmacokinetics | Carcinoma, Non-Small-Cell Lung - genetics | Pyrimidines - administration & dosage | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Acrylamides - administration & dosage | Pyrimidines - adverse effects | Pyrimidines - pharmacokinetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Acrylamides - adverse effects | Clinical trials | Care and treatment | Usage | Diagnosis | Lung cancer, Non-small cell | Hyperglycemia | Chemotherapy | Epidermal growth factor | Inhibitor drugs | Epidermal growth factor receptors | Lung cancer | Genes | Non-small cell lung carcinoma | Antitumor activity | Pharmacokinetics | Patients | Index Medicus | Abridged Index Medicus
Journal Article
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 05/2018, Volume 38, Issue 38, pp. 708 - 715
Non-small cell lung cancer (NSCLC) has become a prominent example of precision medicine among solid tumor malignancies. Clinical management of NSCLC now... 
Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - therapy | Humans | Lung Neoplasms - pathology | Lung Neoplasms - therapy | Biomarkers, Tumor | Precision Medicine - methods
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2013, Volume 19, Issue 11, pp. 1469 - 1472
Journal Article
The Journal of molecular diagnostics : JMD, 05/2019
Chromosomal rearrangements involving the NTRK1, NTRK2, and NTRK3 genes (NTRK gene fusions), which encode the high-affinity nerve growth factor receptor,... 
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2012, Volume 18, Issue 5, pp. 1472 - 1482
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 12/2012, Volume 7, Issue 12, pp. 1807 - 1814
Many patients with oncogene-driven non–small-cell lung cancer (NSCLC) treated with tyrosine kinase inhibitors experience limited sites of disease progression.... 
anaplastic lymphoma kinase gene arrangement non–small-cell lung cancer | EGFR-mutant non–small-cell lung cancer | Radiation therapy | Oligoprogressive disease | anaplastic lymphoma kinase gene arrangement non-small-cell lung cancer | EGFR-mutant non-small-cell lung cancer | PHASE-I/II TRIAL | ACQUIRED-RESISTANCE | BODY RADIATION-THERAPY | DOSE WEEKLY ERLOTINIB | BREAST-CANCER | LIVER METASTASES | SYNCHRONOUS BRAIN METASTASES | STEREOTACTIC RADIOSURGERY | ONCOLOGY | LEPTOMENINGEAL METASTASES | RESPIRATORY SYSTEM | RECURRENT MALIGNANT GLIOMAS | Erlotinib Hydrochloride | Receptor, Epidermal Growth Factor - genetics | Pyrazoles - therapeutic use | Prognosis | Follow-Up Studies | Lung Neoplasms - mortality | Humans | Middle Aged | Catheter Ablation | Lung Neoplasms - pathology | Male | Young Adult | Brain Neoplasms - secondary | Aged, 80 and over | Adult | Female | Retrospective Studies | Brain Neoplasms - mortality | Pyridines - therapeutic use | Carcinoma, Non-Small-Cell Lung - pathology | Survival Rate | Combined Modality Therapy | Lung Neoplasms - therapy | Mutation - genetics | Carcinoma, Non-Small-Cell Lung - mortality | Disease Progression | Carcinoma, Non-Small-Cell Lung - therapy | Receptor Protein-Tyrosine Kinases - genetics | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Gene Rearrangement | Brain Neoplasms - therapy | Aged | Neoplasm Staging
Journal Article
Clinical Nuclear Medicine, ISSN 0363-9762, 01/2015, Volume 40, Issue 1, pp. 79 - 81
ABSTRACTA 35-year-old man presented to the emergency department with a worsening cough and a history of unintended weight loss. Chest radiograph revealed a... 
Lung - pathology | Hamartoma - diagnostic imaging | Humans | Male | Tomography, X-Ray Computed | Lung - diagnostic imaging | Positron-Emission Tomography | Hamartoma - pathology | Multimodal Imaging | Bone and Bones - diagnostic imaging | Adult | Fluorodeoxyglucose F18 | Radiopharmaceuticals
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 03/2018, Volume 142, Issue 3, pp. 321 - 346
Journal Article