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American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 10/2008, Volume 295, Issue 4, pp. 833 - 842
Alcoholic fatty liver is associated with inhibition of sirtuin 1 (SIRT1) and AMP-activated kinase (AMPK), two critical signaling molecules regulating the... 
Sirtuin 1 | Alcoholic liver steatosis | Acetylation | Lipid metabolism | Peroxisome proliferator-activated receptor γ coactivator α | AMP-activated kinase | Sterol regulatory element-binding protein 1c | sirtuin 1 | DIETARY SATURATED FAT | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | LIPID-METABOLISM | alcoholic liver steatosis | lipid metabolism | MITOCHONDRIAL-FUNCTION | ENDOPLASMIC-RETICULUM STRESS | peroxisome proliferator-activated receptor gamma coactivator alpha | acetylation | sterol regulatory element-binding protein 1c | MAMMALIAN SIRTUIN-1 | TRANSCRIPTION FACTOR FOXO1 | INDUCED OXIDATIVE STRESS | ADIPONECTIN SECRETION | GASTROENTEROLOGY & HEPATOLOGY | CALORIE RESTRICTION | Up-Regulation | Ethanol - toxicity | Stilbenes - therapeutic use | Mice, Inbred C57BL | Receptors, Adiponectin - metabolism | Male | Sirtuins - biosynthesis | Animals | Adenylate Kinase - metabolism | Fatty Liver, Alcoholic - drug therapy | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Sterol Regulatory Element Binding Protein 1 - antagonists & inhibitors | Adiponectin - metabolism | Trans-Activators - metabolism | Mice | Transcription Factors | Oxidative Stress - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Index Medicus | Liver and Biliary Tract | peroxisome proliferator-activated receptor γ coactivator α
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 3, pp. 801 - 811
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 04/2008, Volume 294, Issue 4, pp. 892 - 898
Chronic ethanol feeding causes liver steatosis in animal models by upregulating the sterol regulatory element-binding protein 1 (SREBP-1), which subsequently... 
Alcoholic liver steatosis | Sterol regulatory element-binding protein-1c | Acetylation | Coactivator-1α | Lipid metabolism | Peroxisome proliferator-activated receptor-γ | TRANSCRIPTION FACTORS | RAT-LIVER | LIFE-SPAN | OXIDATIVE STRESS | PHYSIOLOGY | FATTY-ACID SYNTHESIS | sterol regulatory element-binding protein-1c | ELEMENT-BINDING PROTEIN-1 | alcoholic liver steatosis | lipid metabolism | MITOCHONDRIAL-FUNCTION | SREBP FAMILY | ENDOPLASMIC-RETICULUM STRESS | peroxisome proliferator-activated receptor-gamma coactivator-1 alpha | acetylation | GASTROENTEROLOGY & HEPATOLOGY | CALORIE RESTRICTION | Enzyme Activators - pharmacology | Gene Expression Regulation, Enzymologic - drug effects | Transcription, Genetic - drug effects | Liver - enzymology | Ethanol - toxicity | Ethanol - administration & dosage | Stilbenes - pharmacology | Fatty Liver, Alcoholic - metabolism | Glycerol-3-Phosphate O-Acyltransferase - metabolism | Transfection | Lipogenesis - genetics | Liver - drug effects | RNA Interference | Sirtuin 1 | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Sirtuins - genetics | Alcohol Drinking - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Disease Models, Animal | Glycerol-3-Phosphate O-Acyltransferase - genetics | Down-Regulation | Fatty Liver, Alcoholic - etiology | Liver - metabolism | Rats | Stearoyl-CoA Desaturase - genetics | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Lipogenesis - drug effects | Cell Line, Tumor | Stearoyl-CoA Desaturase - metabolism | Trans-Activators - metabolism | Transcription Factors | Sirtuins - antagonists & inhibitors | Sirtuins - metabolism | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 05/2009, Volume 296, Issue 5, pp. G1047 - G1053
Journal Article
Experimental Brain Research, ISSN 0014-4819, 04/2010, Volume 202, Issue 2, p. 885
Byline: Paul E. Gottschall (1), Joanne M. Ajmo (2), Autumn K. Eakin (2), Matthew D. Howell (1), Hina Mehta (1), Lauren A. Bailey (1) Keywords: Synapse;... 
Viral antibodies | Nervous system diseases | Analysis | Physiological aspects | Antibodies | Genetic aspects | Intermediate filament proteins | Enzyme-linked immunosorbent assay | Nerve proteins | Protein binding
Journal Article
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 01/2013, Volume 304, Issue 1, pp. G38 - G47
Ethanol administration exacerbates the abnormalities in hepatic lipid oxidation in genetically obese mice. Am J Physiol Gastrointest Liver Physiol 304:... 
Ethanol and obesity synergism | Signal transduction | Fatty liver disease | Lipid metabolism | LOCALIZATION | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | ethanol and obesity synergism | signal transduction | lipid metabolism | ALCOHOLIC FATTY LIVER | NONALCOHOLIC STEATOHEPATITIS | SIRT1 | fatty liver disease | STEATOSIS | DISEASE | BODY-MASS INDEX | PPAR-GAMMA | ENERGY-METABOLISM | GASTROENTEROLOGY & HEPATOLOGY | AMP-Activated Protein Kinases - metabolism | Liver - pathology | Fatty Liver - pathology | Phosphatidate Phosphatase - metabolism | Obesity - genetics | Sirtuin 1 - genetics | Central Nervous System Depressants - pharmacology | Lipid Peroxidation - drug effects | Real-Time Polymerase Chain Reaction | Fatty Liver - metabolism | Oxidation-Reduction | Liver - metabolism | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Organ Size - physiology | Cell Nucleus - ultrastructure | DNA Primers | Blotting, Western | Obesity - metabolism | Obesity - pathology | AMP-Activated Protein Kinases - physiology | Ethanol - pharmacology | PPAR gamma - physiology | Animals | Signal Transduction - drug effects | Sirtuin 1 - physiology | Fluorescent Antibody Technique | Lipid Metabolism - drug effects | Mice, Obese | Mice | Body Weight - physiology | Cell Nucleus - drug effects | Obesity | Liver diseases | Alcohol, Denatured | Physiological aspects | Development and progression | Aspartate | Alcohol | Health aspects | Liver and Biliary Tract
Journal Article
Brain Research, ISSN 0006-8993, 07/2019, Volume 1715, pp. 94 - 105
Inflammation causes activation of nociceptive sensory nerves, resulting in debilitating sensations and reflexes. Inflammation also induces mitochondrial... 
Nociceptor | Mitochondria | Reactive oxygen species | TRPA1 | C-fiber | Antimycin A | TRPV1 | Vagal | OXYGEN SPECIES PRODUCTION | NERVES | CYSTEINE | NEUROSCIENCES | C-FIBERS | CAPSAICIN RECEPTOR | PAIN | ENDOTHELIAL-CELLS | CALCIUM | ION-CHANNEL | RECEPTOR POTENTIAL A1
Journal Article
Journal Article
Journal of Nutrition, ISSN 0022-3166, 03/2008, Volume 138, Issue 3, pp. 497 - 501
This study was undertaken to elucidate the mechanism underling the protective effect of a high saturated fat (HSF) diet against the development of alcoholic... 
Journal Article
Hepatology, ISSN 0270-9139, 12/2013, Volume 58, Issue 6, pp. 1953 - 1963
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2012, Volume 418, Issue 2, pp. 267 - 272
Journal Article