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Science, ISSN 0036-8075, 12/2008, Volume 322, Issue 5909, pp. 1839 - 1842
Differences in the amount of fetal hemoglobin (HbF) that persists into adulthood affect the severity of sickle cell disease and the ?-thalassemia syndromes.... 
Protein isoforms | K562 cells | Erythroblasts | Genes | Cell lines | Small interfering RNA | Genetic loci | Reports | Erythroid cells | Gene expression | Hemoglobins | LOCUS-CONTROL REGION | COMPLEX | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | ZINC-FINGER PROTEIN | DIFFERENTIATION | RECRUITS | BETA-THALASSEMIA | LINEAGE | GENOME-WIDE ASSOCIATION | Erythropoiesis | Fetal Hemoglobin - biosynthesis | Multigene Family | Mi-2 Nucleosome Remodeling and Deacetylase Complex | Humans | Erythroblasts - metabolism | gamma-Globins - metabolism | Protein Isoforms - metabolism | RNA Interference | Transcription, Genetic | gamma-Globins - genetics | Nuclear Proteins - genetics | Down-Regulation | Cells, Cultured | Erythroid Cells - metabolism | Gene Expression Regulation | Histone Deacetylases - metabolism | Nuclear Proteins - metabolism | GATA1 Transcription Factor - metabolism | beta-Globins - genetics | Hemoglobinopathies - therapy | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | beta-Globins - metabolism | Fetal Hemoglobin - genetics | K562 Cells | Cell Line, Tumor | Erythroid Precursor Cells - metabolism | Mice | Polymorphism, Single Nucleotide | Protein Isoforms - genetics | Sickle cell anemia | Physiological aspects | Thalassemia | Genetic aspects | Risk factors | Fetal hemoglobin | Medical research | Genotype & phenotype | Hematology | Sickle cell disease | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 02/2012, Volume 45, Issue 3, pp. 330 - 343
Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian... 
TRANSFORMATION | MAINTENANCE | ADULT HEMATOPOIESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMATOPOIETIC STEM-CELLS | CBFA2 | MEGAKARYOCYTE | MICE | DIFFERENTIATION | RUNX1 | HAPLOINSUFFICIENCY | CELL BIOLOGY | Chromatin - metabolism | Thymocytes - metabolism | Protein Multimerization | Gene Expression Profiling | Core Binding Factor beta Subunit - genetics | Zebrafish - embryology | Gene Knockdown Techniques | T-Lymphocytes - metabolism | Hematopoietic Stem Cells - physiology | Repressor Proteins - isolation & purification | Megakaryocytes - metabolism | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Core Binding Factor beta Subunit - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | Core Binding Factor Alpha 2 Subunit - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Polycomb-Group Proteins | Zebrafish - genetics | Mice, Knockout | Animals | Chromatography, Affinity | Polycomb Repressive Complex 1 | Protein Binding | Mice | Ubiquitin-Protein Ligases - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Cluster Analysis | Computer science | Employee recruitment | Chromatin | Genomics | Genes | Stem cells | Chemical properties | DNA binding proteins | Artificial intelligence | Genetic research | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 2010, Volume 142, Issue 1, pp. 133 - 143
Recent genome-wide studies have demonstrated that pausing of RNA polymerase II (Pol II) occurred on many vertebrate genes. By genetic studies in the zebrafish... 
RNA | DEV BIO | Dev Bio | RNA-POLYMERASE-II | DOMAIN | ZEBRAFISH | HEMATOPOIESIS | EMBRYO | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | PAF1 COMPLEX | GENES | GATA-1 | P-TEFB | CELL BIOLOGY
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0125617 - e0125617
OXPHOS is believed to play an important role in non-alcoholic fatty liver disease (NAFLD), however, precise mechanisms whereby OXPHOS influences lipid... 
RESPIRATORY-CHAIN | PPAR-ALPHA | PROTEIN-KINASE-C | MITOCHONDRIAL ABNORMALITIES | ACTIVATION | HOMEOSTASIS | HEPATIC INSULIN-RESISTANCE | STEATOSIS | MULTIDISCIPLINARY SCIENCES | OXIDASE DEFICIENCY | STEATOHEPATITIS | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Humans | Non-alcoholic Fatty Liver Disease - etiology | Hepatocytes - pathology | Male | Sirtuin 3 - deficiency | Hepatocytes - metabolism | Neoplasm Proteins - metabolism | Mitochondria - genetics | Diet, High-Fat | Lipid Metabolism - genetics | Neoplasm Proteins - genetics | Fatty Acids - metabolism | NAD - metabolism | Sirtuin 3 - genetics | Non-alcoholic Fatty Liver Disease - genetics | Oxidation-Reduction | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Insulin Resistance | Oxidative Phosphorylation | Protein Kinase C-epsilon - genetics | Mice, Transgenic | Mitochondria - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Mitochondria - pathology | Animals | Protein Kinase C-epsilon - metabolism | Mice | Primary Cell Culture | Cytochrome | Reactive oxygen species | Protein kinase C | Phosphorylation | Liver | Homeostasis | Lipids | Kinases | Medical schools | Proteins | Fatty liver | NADH | Rodents | Oxidation | Obesity | Liver diseases | Pharmacology | Inflammation | Metabolism | Gene expression | Insulin | Fatty acids | NAD | Medicine | Mitigation | Hepatocytes | Nicotinamide adenine dinucleotide | Cristae | Insulin resistance | Diabetes | Respiration | Index Medicus
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2014, Volume 124, Issue 2, pp. 768 - 784
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3292 - 3304
Journal Article
Journal Article
Cell, ISSN 0092-8674, 07/2010, Volume 142, Issue 1, pp. 133 - 143
Recent genome-wide studies have demonstrated that pausing of RNA polymerase II (Pol II) occurred on many vertebrate genes. By genetic studies in the zebrafish... 
Journal Article
Cell, 07/2010, Volume 142, Issue 1, pp. 133 - 143
Recent genome-wide studies have demonstrated that pausing of RNA polymerase II (Pol II) occurred on many vertebrate genes. By genetic studies in the zebrafish... 
Erythropoiesis | Transcription Factors - metabolism | Animals | Zebrafish Proteins - metabolism | Humans | Zebrafish - metabolism | Cells, Cultured | Erythroid Cells - metabolism | Cell Line, Tumor | Transcription, Genetic | RNA Polymerase II - metabolism | Zebrafish - embryology | Index Medicus
Journal Article
Pediatric Neurology, ISSN 0887-8994, 1995, Volume 13, Issue 2, pp. 175 - 177
Journal Article
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