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index medicus (7) 7
malaria (6) 6
children (5) 5
humans (5) 5
infant (5) 5
parasitic diseases (5) 5
immunogenicity (4) 4
incidence (4) 4
infants (4) 4
malaria vaccine (4) 4
prevention (4) 4
vaccines (4) 4
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clinical trials (3) 3
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immunization (3) 3
malaria vaccines - adverse effects (3) 3
malaria vaccines - immunology (3) 3
malaria, falciparum - epidemiology (3) 3
malaria, falciparum - prevention & control (3) 3
male (3) 3
medicine, general & internal (3) 3
plasmodium falciparum - immunology (3) 3
risk factors (3) 3
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double-blind (2) 2
drug therapy (2) 2
efficacy (2) 2
health aspects (2) 2
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immunology (2) 2
infectious diseases (2) 2
intention to treat analysis (2) 2
medicine (2) 2
medicine and health sciences (2) 2
parasitology (2) 2
plasmodium-falciparum infection (2) 2
prevalence (2) 2
research (2) 2
research article (2) 2
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: malaria (1) 1
adolescent (1) 1
adult (1) 1
africa south of the sahara - epidemiology (1) 1
african children (1) 1
age factors (1) 1
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anatomy (1) 1
animal cells (1) 1
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1. Full Text Malaria hotspots defined by clinical malaria, asymptomatic carriage, PCR and vector numbers in a low transmission area on the Kenyan Coast
by Kangoye, David Tiga and Noor, Abdisalan and Midega, Janet and Mwongeli, Joyce and Mkabili, Dora and Mogeni, Polycarp and Kerubo, Christine and Akoo, Pauline and Mwangangi, Joseph and Drakeley, Chris and Marsh, Kevin and Bejon, Philip and Njuguna, Patricia
Malaria Journal, ISSN 1475-2875, 04/2016, Volume 15, Issue 1, p. 213
Background: Targeted malaria control interventions are expected to be cost-effective. Clinical, parasitological and serological markers of malaria transmission... 
Spatial scan statistic | Malaria | Targeted intervention | Hotspots | Transmission | Antibodies | Asymptomatic parasitemia | Serology | INFECTIOUS DISEASES | PLASMODIUM-FALCIPARUM INFECTION | RISK | KILIFI DISTRICT | TROPICAL MEDICINE | CHILDREN | DYNAMICS | ANTIBODY-RESPONSES | EXPOSURE | PARASITOLOGY | Prevalence | Cross-Sectional Studies | Kenya - epidemiology | Asymptomatic Infections - epidemiology | Humans | Middle Aged | Child, Preschool | Infant | Malaria - diagnosis | Seroepidemiologic Studies | Anopheles - physiology | Incidence | Young Adult | Animals | Insect Vectors - physiology | Malaria - epidemiology | Population Density | Adolescent | Polymerase Chain Reaction | Adult | Aged | Malaria - transmission | Child | Polymerase chain reaction | Usage | Disease transmission | Distribution | Research | Risk factors
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2. Full Text Clinical laboratory reference values amongst children aged 4 weeks to 17 months in Kilifi, Kenya: A cross sectional observational study
by Gitaka, Jesse and Ogwang, Caroline and Ngari, Moses and Akoo, Pauline and Olotu, Ally and Kerubo, Christine and Fegan, Greg and Njuguna, Patricia and Nyakaya, Godfrey and Otieno, Tuda and Mwambingu, Gabriel and Awuondo, Ken and Lowe, Brett and Chilengi, Roma and Berkley, James A
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0177382 - e0177382
Reference intervals for clinical laboratory parameters are important for assessing eligibility, toxicity grading and management of adverse events in clinical... 
IN-VITRO | IMMUNOLOGICAL REFERENCE VALUES | COAST | AFRICAN CHILDREN | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | INFANTS | MALARIA | IRON-DEFICIENCY | REFERENCE RANGES | PEDIATRIC REFERENCE INTERVALS | Confidence Intervals | Clinical Laboratory Services | Cross-Sectional Studies | Humans | Female | Infant | Male | Reference Values | Leukocyte Count | Kenya | Infant, Newborn | Clinical trials | Usage | Children | Health aspects | Developed countries | Disease | Laboratories | Toxicity | Communities | Infants | Biochemistry | Vaccines | Family medical history | Blood | Tropical diseases | Confidence intervals | Illnesses | Gender aspects | Grading | Cross sections | Age | Vector-borne diseases | Medical research | Parasitology | Statistical analysis | Hematology | Malaria | Rural areas | Norms | Sex differences | Medicine | Nutrition research | Platelets | Hygiene | Community | Index Medicus
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3. Full Text A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
by Agnandji, Selidji Todagbe and Lell, Bertrand and Fernandes, José Francisco and Abossolo, Béatrice Peggy and Methogo, Barbara Gaelle Nfono Ondo and Kabwende, Anita Lumeka and Adegnika, Ayola Akim and Mordmüller, Benjamin and Issifou, Saadou and Kremsner, Peter Gottfried and Sacarlal, Jahit and Aide, Pedro and Lanaspa, Miguel and Aponte, John J and Machevo, Sonia and Acacio, Sozinho and Bulo, Helder and Sigauque, Betuel and Macete, Eusébio and Alonso, Pedro and Abdulla, Salim and Salim, Nahya and Minja, Rose and Mpina, Maxmillian and Ahmed, Saumu and Ali, Ali Mohammed and Mtoro, Ali Takadir and Hamad, Ali Said and Mutani, Paul and Tanner, Marcel and Tinto, Halidou and D'Alessandro, Umberto and Sorgho, Hermann and Valea, Innocent and Bihoun, Biébo and Guiraud, Issa and Kaboré, Berenger and Sombié, Olivier and Guiguemdé, Robert Tinga and Ouédraogo, Jean Bosco and Hamel, Mary J and Kariuki, Simon and Oneko, Martina and Odero, Chris and Otieno, Kephas and Awino, Norbert and McMorrow, Meredith and Muturi-Kioi, Vincent and Laserson, Kayla F and Slutsker, Laurence and Otieno, Walter and Otieno, Lucas and Otsyula, Nekoye and Gondi, Stacey and Otieno, Allan and Owira, Victorine and Oguk, Esther and Odongo, George and Ben Woods, Jon and Ogutu, Bernhards and Njuguna, Patricia and Chilengi, Roma and Akoo, Pauline and Kerubo, Christine and Maingi, Charity and Lang, Trudie and Olotu, Ally and Bejon, Philip and Marsh, Kevin and Mwambingu, Gabriel and Owusu-Agyei, Seth and Asante, Kwaku Poku and Osei-Kwakye, Kingsley and Boahen, Owusu and Dosoo, David and Asante, Isaac and Adjei, George and Kwara, Evans and Chandramohan, Daniel and Greenwood, Brian and Lusingu, John and Gesase, Samwel and Malabeja, Anangisye and Abdul, Omari and Mahende, Coline and Liheluka, Edwin and Malle, Lincoln and Lemnge, Martha and Theander, Thor G and Drakeley, Chris and Ansong, Daniel and Agbenyega, Tsiri and Adjei, Samuel and Boateng, Harry Owusu and Rettig, Theresa and Bawa, John and Sylverken, Justice and Sambian, David and Sarfo, Anima and Agyekum, Alex and ... and The RTS,S Clinical Trials Partnership and RTS S Clin Trials Partnership and RTS,S Clinical Trials Partnership
The New England Journal of Medicine, ISSN 0028-4793, 12/2012, Volume 367, Issue 24, pp. 2284 - 2295
In this ongoing phase 3 study of over 6000 infants (6 to 12 weeks of age) at 11 centers in Africa, the RTS,S/AS01 vaccine had 30% efficacy in preventing the... 
CASE-DEFINITION | IMMUNIZATION | MEDICINE, GENERAL & INTERNAL | IMMUNOGENICITY | FALCIPARUM-MALARIA | EFFICACY | DATA-COLLECTION | III MULTICENTER TRIAL | DOUBLE-BLIND | SAFETY DATA | CANDIDATE VACCINE | Malaria, Falciparum - prevention & control | Humans | Africa | Proportional Hazards Models | Infant | Male | Treatment Outcome | Plasmodium falciparum - immunology | Vaccines, Synthetic - immunology | Incidence | Vaccines, Synthetic - adverse effects | Malaria Vaccines - adverse effects | Intention to Treat Analysis | Malaria Vaccines - immunology | Malaria, Falciparum - epidemiology | Female | Immunization Schedule | Prevention | Drugs | Dose-response relationship (Biochemistry) | Malaria | Malaria vaccine | Dosage and administration | Product/Service Evaluations | Drug therapy | Confidence intervals | Vaccines | Appropriate technology | Age
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4. Full Text First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
by Agnandji, Selidji Todagbe and Lell, Bertrand and Soulanoudjingar, Solange Solmeheim and Fernandes, José Francisco and Abossolo, Béatrice Peggy and Conzelmann, Cornelia and Methogo, Barbara Gaelle Nfono Ondo and Doucka, Yannick and Flamen, Arnaud and Mordmüller, Benjamin and Issifou, Saadou and Kremsner, Peter Gottfried and Sacarlal, Jahit and Aide, Pedro and Lanaspa, Miguel and Aponte, John J and Nhamuave, Arlindo and Quelhas, Diana and Bassat, Quique and Mandjate, Sofia and Macete, Eusébio and Alonso, Pedro and Abdulla, Salim and Salim, Nahya and Juma, Omar and Shomari, Mwanajaa and Shubis, Kafuruki and Machera, Francisca and Hamad, Ali Said and Minja, Rose and Mpina, Maxmillian and Mtoro, Ali and Sykes, Alma and Ahmed, Saumu and Urassa, Alwisa Martin and Ali, Mohammed and Mwangoka, Grace and Tanner, Marcel and Tinto, Halidou and D'Alessandro, Umberto and Sorgho, Hermann and Valea, Innocent and Tahita, Marc Christian and Kaboré, William and Ouédraogo, Sayouba and Sandrine, Yara and Guiguemdé, Robert Tinga and Ouédraogo, Jean Bosco and Hamel, Mary J and Kariuki, Simon and Odero, Chris and Oneko, Martina and Otieno, Kephas and Awino, Norbert and Omoto, Jackton and Williamson, John and Muturi-Kioi, Vincent and Laserson, Kayla F and Slutsker, Laurence and Otieno, Walter and Otieno, Lucas and Nekoye, Otsyula and Gondi, Stacey and Otieno, Allan and Ogutu, Bernhards and Wasuna, Ruth and Owira, Victorine and Jones, David and Onyango, Agnes Akoth and Njuguna, Patricia and Chilengi, Roma and Akoo, Pauline and Kerubo, Christine and Gitaka, Jesse and Maingi, Charity and Lang, Trudie and Olotu, Ally and Tsofa, Benjamin and Bejon, Philip and Peshu, Norbert and Marsh, Kevin and Owusu-Agyei, Seth and Asante, Kwaku Poku and Osei-Kwakye, Kingsley and Boahen, Owusu and Ayamba, Samuel and Kayan, Kingsley and Owusu-Ofori, Ruth and Dosoo, David and Asante, Isaac and Adjei, George and Kwara, Evans and Chandramohan, Daniel and Greenwood, Brian and Lusingu, John and Gesase, Samwel and Malabeja, Anangisye and Abdul, Omari and Kilavo, Hassan and Mahende, Coline and ... and The RTS,S Clinical Trials Partnership and S Clinical Trials Partnership and RTS,S Clinical Trials Partnership
The New England Journal of Medicine, ISSN 0028-4793, 11/2011, Volume 365, Issue 20, pp. 1863 - 1875
Each year, about 225 million persons have malaria, with some 781,000 associated deaths. In a preliminary report of a phase 3 trial in African children, the... 
IMMUNIZATION | MEDICINE, GENERAL & INTERNAL | IMMUNOGENICITY | EFFICACY | SAFETY | PLASMODIUM-FALCIPARUM INFECTION | III MULTICENTER TRIAL | MOZAMBICAN CHILDREN | INFANTS | EXPANDED-PROGRAM | CANDIDATE VACCINE | Malaria, Falciparum - prevention & control | Age Factors | Double-Blind Method | Follow-Up Studies | Humans | Parasite Load | Africa | Infant | Male | Treatment Outcome | Plasmodium falciparum - immunology | Meningitis - epidemiology | Meningitis - etiology | Incidence | Malaria, Falciparum - parasitology | Malaria Vaccines - adverse effects | Plasmodium falciparum - isolation & purification | Seizures - epidemiology | Intention to Treat Analysis | Malaria Vaccines - immunology | Malaria, Falciparum - epidemiology | Seizures - etiology | Female | Prevention | Dosage and administration | Malaria | Drug therapy | Malaria vaccine | Drug utilization | Immunization | Enrollments | Mortality | Vaccination | Vaccines | Tropical diseases | Motivation | Immunogenicity | Surveillance | Rabies | Combined vaccines | Children | Age | Seizures
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5. Full Text Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites
by Agnandji, Selidji Todagbe and Lell, Bertrand and Fernandes, José Francisco and Abossolo, Béatrice Peggy and Kabwende, Anita Lumeka and Adegnika, Ayola Akim and Mordmüller, Benjamin and Issifou, Saadou and Kremsner, Peter Gottfried and Loembe, Marguerite Massinga and Sacarlal, Jahit and Aide, Pedro and Madrid, Lola and Lanaspa, Miguel and Mandjate, Sofia and Aponte, John J and Bulo, Helder and Nhama, Abel and Macete, Eusébio and Alonso, Pedro and Abdulla, Salim and Salim, Nahya and Mtoro, Ali Takadir and Mutani, Paul and Tanner, Marcel and Mavere, Caroline and Mwangoka, Grace and Lweno, Omar and Juma, Omar Ali and Shekalaghe, Seif and Tinto, Halidou and D'Alessandro, Umberto and Sorgho, Hermann and Valea, Innocent and Ouédraogo, Jean Bosco and Lompo, Palpouguini and Diallo, Salou and Traore, Ousmane and Bassole, Armand and Dao, Edgard and Hamel, Mary J and Kariuki, Simon and Oneko, Martina and Odero, Chris and Otieno, Kephas and Awino, Norbert and Muturi-Kioi, Vincent and Omoto, Jackton and Laserson, Kayla F and Slutsker, Laurence and Otieno, Walter and Otieno, Lucas and Otsyula, Nekoye and Gondi, Stacey and Otieno, Allan and Ogutu, Bernhards and Ochola, Jew and Onyango, Irene and Oyieko, Janet and Njuguna, Patricia and Chilengi, Roma and Akoo, Pauline and Kerubo, Christine and Maingi, Charity and Olotu, Ally and Bejon, Philip and Marsh, Kevin and Mwabingu, Gabriel and Gitaka, Jesse and Owusu-Agyei, Seth and Asante, Kwaku Poku and Boahen, Owusu and Dosoo, David and Adjei, George and Adeniji, Elisha and Yawson, Abena Kunadu and Kayan, Kingsley and Chandramohan, Daniel and Greenwood, Brian and Lusingu, John and Gesase, Samwel and Malabeja, Anangisye and Abdul, Omari and Mahende, Coline and Liheluka, Edwin and Lemnge, Martha and Theander, Thor G and Drakeley, Chris and Mbwana, Joyce and Ansong, Daniel and Agbenyega, Tsiri and Adjei, Samuel and Boateng, Harry Owusu and Rettig, Theresa and Bawa, John and Sylverken, Justice and Sambian, David and Sarfo, Anima and Agyekum, Alex and Martinson, Francis and ... and RTS S Clinical Trials Partnership and RTS,S Clinical Trials Partnership and The RTS,S Clinical Trials Partnership
PLoS Medicine, ISSN 1549-1277, 2014, Volume 11, Issue 7, p. e1001685
Background: A malaria vaccine could be an important addition to current control strategies. We report the safety and vaccine efficacy (VE) of the RTS, S/AS01... 
IMMUNITY | MEDICINE, GENERAL & INTERNAL | TRANSMISSION | IMMUNOGENICITY | MULTICENTER | CIRCUMSPOROZOITE PROTEIN | SUSCEPTIBILITY | DOUBLE-BLIND | RESISTANCE | INFECTION | PROGRAM | Malaria, Falciparum - prevention & control | Malaria Vaccines - administration & dosage | Prevalence | Vaccination - standards | Humans | Malaria Vaccines - adverse effects | Malaria Vaccines - immunology | Malaria, Falciparum - epidemiology | Infant | Plasmodium falciparum - immunology | Africa South of the Sahara - epidemiology | Incidence | Prevention | Infants (Newborn) | Complications and side effects | Malaria | Analysis | Malaria vaccine | Clinical trials | Infants | Research | Health aspects | Risk factors | Immunization | Vaccines | Parasites
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6. Full Text Safety and immunogenicity of the RTS,S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa
by Otieno, Lucas and Guerra Mendoza, Yolanda and Adjei, Samuel and Agbenyega, Tsiri and Agnandji, Selidji Todagbe and Aide, Pedro and Akoo, Pauline and Ansong, Daniel and Asante, Kwaku Poku and Berkley, James A and Gesase, Samwel and Hamel, Mary J and Hoffman, Irving and Kaali, Seyram and Kamthunzi, Portia and Kariuki, Simon and Kremsner, Peter and Lanaspa, Miguel and Lell, Bertrand and Lievens, Marc and Lusingu, John and Malabeja, Anangisye and Masoud, Nahya Salim and Mtoro, Ali Takadir and Njuguna, Patricia and Ofori-Anyinam, Opokua and Otieno, Godfrey Allan and Otieno, Walter and Owusu-Agyei, Seth and Schuerman, Lode and Sorgho, Hermann and Tanner, Marcel and Tinto, Halidou and Valea, Innocent and Vandoolaeghe, Pascale and Sacarlal, Jahit and Oneko, Martina
Vaccine, ISSN 0264-410X, 11/2019
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7. Full Text Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa
by Guerra Mendoza, Yolanda and Garric, Elodie and Leach, Amanda and Lievens, Marc and Ofori-Anyinam, Opokua and Pirçon, Jean-Yves and Stegmann, Jens-Ulrich and Vandoolaeghe, Pascale and Otieno, Lucas and Otieno, Walter and Owusu-Agyei, Seth and Sacarlal, Jahit and Masoud, Nahya Salim and Sorgho, Hermann and Tanner, Marcel and Tinto, Halidou and Valea, Innocent and Mtoro, Ali Takadir and Njuguna, Patricia and Oneko, Martina and Otieno, Godfrey Allan and Otieno, Kephas and Gesase, Samwel and Hamel, Mary J and Hoffman, Irving and Kaali, Seyram and Kamthunzi, Portia and Kremsner, Peter and Lanaspa, Miguel and Lell, Bertrand and Lusingu, John and Malabeja, Anangisye and Aide, Pedro and Akoo, Pauline and Ansong, Daniel and Asante, Kwaku Poku and Berkley, James A and Adjei, Samuel and Agbenyega, Tsiri and Agnandji, Selidji Todagbe and Schuerman, Lode
Human Vaccines & Immunotherapeutics, ISSN 2164-5515, 10/2019, Volume 15, Issue 10, pp. 2386 - 2398
A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS,S/AS01 vaccine efficacy against malaria. We now present... 
RTS,S/AS01 vaccine | (5-10): Malaria | cerebral malaria | safety | febrile convulsions | meningitis | Infants | Vacuna de la malària | Children | Malaria vaccine | Sub-Saharan Africa | Àfrica subsahariana
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8. Full Text Enrolling study personnel in Ebola vaccine trials: from guidelines to practice in a non-epidemic context
by Lhomme, E and Modet, C and Augier, A and Faye, S and Dabakuyo-Yonli, TS and Levy-Marchal, C and D'Ortenzio, E and Yazdanpanah, Y and Chene, G and Beavogui, AH and Richert, L and Abdoulaye, C and Aboulhab, J and Akpa, E and Akoo, P and Akpata, R and Albert, S and Ale, B and Anoma, S and Andrews, BC and Assiandi, SS and Badio, M and Bagayoko, A and Bakare, N and Balde, A and de Saint Fare, EB and Barrington, K and Baseler, B and Bauder, A and Bauduin, C and Bawo, L and Belson, M and Bererd, M and Beyslow, T and Binachon, B and Blie, J and Bockstal, V and Boire, Y and Boison, P and Bolay, F and Boly, A and Borg, AG and Bowers, D and Browne, S and Cagnard, B and Cahill, K and Cash, J and Camara, K and Camara, M and Campion, C and Chai, SP and Chambelin, F and Chieck, K and Ciancia, S and Cisse, PN and Clide, E and Colin, C and Coller, BA and Conde, DS and Cone, K and Connor, L and Couffin-Cardiergues, S and Coulibaly, F and Coulibaly, M and Dabakuyo-Yonli, S and Damerval, T and Davids, B and Deen, GF and Dekeyster, E and Delfraissy, JF and Delmas, C and Dembele, R and Diakite, M and Diallo, A and Diarra, A and Diawara, O and Diop, S and Diouf, W and Doepel, L and Doumbia, S and Doumbia, MM and Douoguih, M and DuChene, A and Duvenhage, M and Eckes, R and Egan, A and Enria, L and Esperou, H and Etienne, C and Eyler, A and Fernandez, J and Fleck, S and Franklin, K and Fusco, D and Gaddah, A and Gaignet, M and Gallagher, K and Gray, M and Gozalbes, JG and Greenwood, B and ... and PREVAC Study Team and PREVAC study team and the PREVAC study team
TRIALS, ISSN 1745-6215, 07/2019, Volume 20, Issue 1, pp. 422 - 6
Background: Enrolling participants in clinical trials can be challenging, especially with respect to prophylactic vaccine trials. The vaccination of study... 
MEDICINE, RESEARCH & EXPERIMENTAL | Ethics | Research participants | Site staff | Low- and middle-income countries | Trial participants | Clinical trials | Employees | Ebola vaccine | Health workers | Prevention | Usage | Viral vaccines | Analysis | Practice guidelines (Medicine) | Ebola virus infections | Risk factors
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