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Profiles of Drug Substances, Excipients and Related Methodology, ISSN 1871-5125, 2019, Volume 44, p. 239
Sorafenib (BAY-43-9006), marketed by Bayer as Nexavar® (USA), is anticancer drug approved by US-FDA for the treatment of unresectable hepatocellular carcinoma... 
Comprehensive profile | Clinical uses | Sorafenib | Hepatocellular carcinoma | Cancer drug | Drug-drug interactions | Pharmacology | Tyrosine kinase inhibitors | Sorafenib - chemistry | Antineoplastic Agents - pharmacology | Sorafenib - pharmacology | Antineoplastic Agents - chemistry
Journal Article
AAPS PharmSciTech, ISSN 1530-9932, 10/2017, Volume 18, Issue 7, pp. 2737 - 2743
The aim of the present study was to ascertain the solubility of nitrendipine (NP), an antihypertensive drug in six different pure solvents such as water, ethyl... 
Biochemistry, general | nitrendipine | Biotechnology | Biomedicine | Pharmacy | dissolution | thermodynamics | solubility | Pharmacology/Toxicology | Apelblat equation | Antihypertensive drugs | Thermodynamics | Esters | Polyethylene glycol | Polyols | Analysis
Journal Article
Saudi Pharmaceutical Journal, ISSN 1319-0164, 2010, Volume 18, Issue 3, pp. 167 - 171
To investigate the potential effects of eleven of the most commonly used Saudi folk herbal medications on the metabolic activity of CYP2C9 in human liver... 
CYP2C9 | Human liver microsomes | Metabolism | Interaction | Tolbutamide | Herb | Short Communication
Journal Article
Journal Article
Saudi Pharmaceutical Journal, ISSN 1319-0164, 07/2018, Volume 26, Issue 5, pp. 673 - 677
The aim of the present study was to investigate the potential effect of thymoquinone (TQ) on the metabolic activity of four major drug metabolizing enzymes in... 
Human liver microsomes | Metabolism | Cytochrome P450 | Thymoquinone | RAT-LIVER | HERBAL MEDICINES | SEEDS | EXTRACTION | RABBITS | OIL | METABOLIC-ACTIVITY | DRUGS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | NIGELLA-SATIVA L | Usage | Quinone | Cytochrome P-450 | Drug metabolism | Genetic aspects | Health aspects | Microsomes
Journal Article
Journal Article
Pharmacological reports : PR, ISSN 1734-1140, 10/2018, Volume 71, Issue 2, p. 201
This study was designed to investigate the effects of dasatinib and nilotinib on the pharmacokinetics of cyclosporine in rats, as these drugs have been... 
Journal Article
Current Analytical Chemistry, ISSN 1573-4110, 2018, Volume 14, Issue 6, pp. 634 - 640
Background: Regorafenib is a multikinase inhibitor, indicated for the treatment of metastatic colorectal cancer and locally advanced, unresectable or... 
Regorafenib | UPLC-MS/MS | Elution | Pharmacokinetics | Bioanalysis | Sorafenib | PERFORMANCE LIQUID-CHROMATOGRAPHY | CHEMISTRY, ANALYTICAL | METABOLITES | ASSAY | sorafenib | elution | pharmacokinetics | bioanalysis | INHIBITOR | BAY 73-4506
Journal Article
International Journal of Analytical Chemistry, ISSN 1687-8760, 02/2019, Volume 2019, pp. 1 - 1
Journal Article
Materials Science & Engineering. C, Biomimetic Materials, Sensors and Systems, ISSN 0928-4931, 07/2017, Volume 76, p. 319
Thymoquinone (TQ) is a poorly water soluble bioactive compound which shows poor oral bioavailability upon oral administration. Due to poor aqueous solubility... 
Formulations | Evaluation | Drug delivery systems | Animal models | Oral administration | Nanoemulsions | Pharmacology | Drug delivery | Bioavailability | Bioactive compounds | Biocompatibility | Dialysis | In vivo methods and tests
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 06/2018, Volume 544, Issue 1, pp. 165 - 171
The purpose of the present study was to determine the solubility of raloxifene hydrochloride (RHCl) in ten solvents: water, ethanol, isopropyl alcohol (IPA),... 
Thermodynamics | Dissolution | Raloxifene hydrochloride | Solubility | Apelblat equation | MOLECULAR-INTERACTIONS | DIFFERENT NEAT SOLVENTS | MAGNESIUM-DL-ASPARTATE | DELIVERY | P-TOLUIC ACID | NANOPARTICLES | DIFFERENT MONO SOLVENTS | PLUS WATER MIXTURES | CALCIUM | PHARMACOLOGY & PHARMACY | OPTIMIZATION | Polyethylene glycol | Pharmacy | Analysis | Dimethyl sulfoxide | Drugstores | Esters | Raloxifene
Journal Article
Current drug delivery, 02/2018, Volume 15, Issue 2, p. 260
Niosomes are non-ionic surfactant vesicles used as drug carriers for encapsulating both hydrophobic and hydrophilic drugs. The aim of the present study was to... 
Journal Article
International journal of analytical chemistry, ISSN 1687-8760, 2019, Volume 2019, p. 6470528
[This corrects the article DOI: 10.1155/2018/2569027.]. 
Journal Article
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