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PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, pp. e50360 - e50360
The zinc (Zn++) transporter ZnT8 plays a crucial role in zinc homeostasis. It's been reported that an acute decrease in ZnT8 levels impairs beta cell function... 
ACTIVATION | PANCREATIC-ISLETS | OXYGEN-INDUCED RETINOPATHY | MULTIDISCIPLINARY SCIENCES | YC-1 | MACULAR DEGENERATION | MICE | KAPPA-B | TYPE-2 | LOCUS | BETA-CELL FUNCTION | Enzyme Activators - pharmacology | Retinal Diseases - prevention & control | Cell Line | Retina - metabolism | Cation Transport Proteins - biosynthesis | Zinc Transporter 8 | Mice, Inbred C57BL | Gene Expression Regulation | Cation Transport Proteins - physiology | Rats | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Retinal Diseases - metabolism | Immunohistochemistry - methods | Indazoles - pharmacology | Animals | Neuroprotective Agents - pharmacology | Image Processing, Computer-Assisted | Retinal Diseases - pathology | Hypoxia | Mice | Retina - pathology | Ischemia - pathology | Immunohistochemistry | Diabetic retinopathy | Zinc compounds | Health aspects | Neuroprotection | Hypoxia-inducible factor 1 | Retinopathy | Pathogenesis | Homeostasis | Retina | Iron | Kinases | Retinal pigment epithelium | Eye | Proteins | Ischemia | Prolactin | Eye injuries | Rodents | Physiology | Localization | Diabetes mellitus | Metabolism | Gene expression | Epithelium | Insulin | Zinc | Zinc transporter | Studies | Polymerase chain reaction | Hospitals | Nitric oxide | Photoreceptors | Eye diseases | Diabetes | Aberration | Transporter | Apoptosis | Polymorphism | Index Medicus
Journal Article
Journal Article
Journal Article
ONCOGENE, ISSN 0950-9232, 04/2016, Volume 35, Issue 15, pp. 1909 - 1918
The BRAF(V600E) mutation is found in approximately 40% of papillary thyroid cancers (PTC). Mice with thyroid-specific expression of BRAF(V600E)... 
CELLS | RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PTEN | ONCOGENE-INDUCED SENESCENCE | CELL BIOLOGY | ONCOLOGY | BRAF MUTATIONS | MOUSE MODEL | IN-VIVO | GENETICS & HEREDITY | SERUM TSH | CARCINOMA | TRANSGENIC MICE | Neoplasm Transplantation | Carcinoma, Papillary - genetics | Tumor Suppressor Protein p53 - biosynthesis | Proto-Oncogene Proteins B-raf - physiology | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Mutation, Missense | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Tumor Suppressor Protein p53 - genetics | Genes, p53 | Cellular Senescence | Female | Indoles - pharmacology | Carcinoma - pathology | Chromones - pharmacology | Neoplasm Proteins - genetics | Chromones - therapeutic use | Morpholines - therapeutic use | Thyrotropin - blood | Down-Regulation | Morpholines - pharmacology | Mice, Transgenic | Proto-Oncogene Proteins c-akt - physiology | Sulfonamides - pharmacology | Tumor Suppressor Protein p53 - deficiency | Carcinoma, Papillary - pathology | Disease Progression | Mice, Knockout | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Thyroid Neoplasms - genetics | Animals | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Sulfonamides - therapeutic use | Mice, Nude | Proto-Oncogene Proteins B-raf - genetics | Thyrotropin - physiology | Phosphatidylinositol 3-Kinases - physiology | Carcinoma - genetics | Indoles - therapeutic use | Neoplasm Proteins - blood | Mice | Mice, Inbred BALB C | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Lymphocytes, Tumor-Infiltrating - immunology | Thyroid Neoplasms - pathology | Index Medicus
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 04/2017, Volume 77, Issue 8, pp. 2161 - 2172
CYP24A1, the primary inactivating enzyme for vitamin D, is often overexpressed in human cancers, potentially neutralizing the antitumor effects of calcitriol,... 
EPITHELIAL-MESENCHYMAL TRANSITION | VITAMIN-D | MURINE MODEL | OVEREXPRESSION | POTENTIAL BIOMARKER | ACTIVATION | ONCOLOGY | MAP KINASE | PROSTATE-CANCER | GENE-EXPRESSION | CARCINOMA
Journal Article
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 2015, Volume 52, Issue 3, pp. 186 - 194
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2009, Volume 50, Issue 8, pp. 1521 - 1537
The effects of dietary monosodium glutamate (MSG) on trans-fatty acid (TFA)-induced nonalcoholic fatty liver disease (NAFLD) are addressed in an animal model.... 
Mitochondria | Peroxisomes | Triglycerides | Trans-fatty acid | Microsomes | Free fatty acids | PPAR-ALPHA | ACIDS | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | free fatty acids | triglycerides | OVEREXPRESSION | OBESITY | INSULIN-RESISTANCE | GENE-EXPRESSION | peroxisomes | STEATOHEPATITIS | MICE | ASSOCIATION | trans-fatty acid | microsomes | ADIPOSE-TISSUE | Liver - pathology | Oligonucleotide Array Sequence Analysis | Fatty Liver - pathology | Cholesterol - blood | Male | Insulin - blood | Leptin - blood | Sodium Glutamate - toxicity | Liver - drug effects | Lipids - blood | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Dietary Fats - administration & dosage | Trans-Activators - genetics | Female | Lipid Metabolism - genetics | Intra-Abdominal Fat - drug effects | Trans Fatty Acids - administration & dosage | Fatty Liver - genetics | Adiposity - drug effects | Fatty Liver - metabolism | Blood Glucose - analysis | Trans Fatty Acids - toxicity | Cell Size - drug effects | Liver - metabolism | Mice, Inbred C57BL | Adiposity - genetics | Gene Expression Regulation - drug effects | Pregnancy | Organ Size - drug effects | Animals | Diet | Sterol Regulatory Element Binding Protein 1 - genetics | Lipid Metabolism - drug effects | Mice | Transcription Factors | Intra-Abdominal Fat - pathology | Sodium Glutamate - administration & dosage | Index Medicus
Journal Article