Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (141) 141
Publication (17) 17
Book Review (11) 11
Book Chapter (1) 1
Conference Proceeding (1) 1
Dissertation (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (83) 83
humans (79) 79
female (55) 55
male (53) 53
immunology (38) 38
child (36) 36
child, preschool (32) 32
mutation (30) 30
asthma (24) 24
infant (22) 22
genetic aspects (21) 21
adolescent (19) 19
adult (19) 19
saudi arabia (18) 18
abridged index medicus (17) 17
research (17) 17
risk factors (17) 17
allergy (16) 16
animals (16) 16
article (15) 15
cytokines (15) 15
disease (15) 15
medical colleges (15) 15
medicine, general & internal (14) 14
pedigree (14) 14
health aspects (13) 13
genotype (12) 12
immunodeficiency (12) 12
infectious diseases (12) 12
respiratory system (12) 12
analysis (11) 11
biomedicine (11) 11
care and treatment (11) 11
disease susceptibility (11) 11
immunity (11) 11
internal medicine (11) 11
mutations (11) 11
alleles (10) 10
allergy and immunology (10) 10
diagnosis (10) 10
genes (10) 10
lymphocytes (10) 10
medical microbiology (10) 10
mice (10) 10
physiological aspects (10) 10
asthma - immunology (9) 9
children (9) 9
consanguinity (9) 9
genetic research (9) 9
genetics (9) 9
interleukin-17 - immunology (9) 9
middle aged (9) 9
patients (9) 9
polymorphism, single nucleotide (9) 9
retrospective studies (9) 9
studies (9) 9
treatment outcome (9) 9
young adult (9) 9
immunologic deficiency syndromes - genetics (8) 8
respiratory tract diseases (8) 8
saudi arabia - epidemiology (8) 8
stem cells (8) 8
asthma - pathology (7) 7
clinical-features (7) 7
deficiency (7) 7
genetic predisposition to disease (7) 7
genetics & heredity (7) 7
hyper-ige syndrome (7) 7
ifn-gamma (7) 7
infections (7) 7
inflammation (7) 7
medicine (7) 7
mortality (7) 7
multidisciplinary sciences (7) 7
original (7) 7
pediatrics (7) 7
proteins (7) 7
severe combined immunodeficiency (7) 7
stem cell transplantation (7) 7
t-lymphocytes - immunology (7) 7
asthma - physiopathology (6) 6
base sequence (6) 6
biochemistry & molecular biology (6) 6
cells, cultured (6) 6
chronic mucocutaneous candidiasis (6) 6
cross-sectional studies (6) 6
development and progression (6) 6
dna mutational analysis (6) 6
expression (6) 6
gene (6) 6
gene mutations (6) 6
hematology (6) 6
homozygote (6) 6
hospitals (6) 6
identification (6) 6
inborn-errors (6) 6
infant, newborn (6) 6
life sciences (6) 6
medical research (6) 6
medicine, research & experimental (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity
by Anne Puel and Sophie Cypowyj and Jacinta Bustamante and Jill F. Wright and Luyan Liu and Hye Kyung Lim and Mélanie Migaud and Laura Israel and Maya Chrabieh and Magali Audry and Matthew Gumbleton and Antoine Toulon and Christine Bodemer and Jamila El-Baghdadi and Matthew Whitters and Theresa Paradis and Jonathan Brooks and Mary Collins and Neil M. Wolfman and Saleh Al-Muhsen and Miguel Galicchio and Laurent Abel and Capucine Picard and Jean-Laurent Casanova
Science, ISSN 0036-8075, 4/2011, Volume 332, Issue 6025, pp. 65 - 68
Chronic mucocutaneous candidiasis disease (CMCD) is characterized by recurrent or persistent infections of the skin, nails, and oral and genital mucosae caused... 
T lymphocytes | Receptors | Cytokines | RESEARCH ARTICLES | Alleles | Fibroblasts | Innate immunity | Infections | Genetic mutation | Immunity | Human genetics | HYPER-IGE SYNDROME | IL-17F | MULTIDISCIPLINARY SCIENCES | HOST-DEFENSE | CYTOKINE | BACTERIAL-INFECTION | DIFFERENTIATION | MUTATIONS | ALBICANS | TH17 CELLS | FAMILY | Candida albicans | Candidiasis, Chronic Mucocutaneous - genetics | Humans | Candidiasis, Chronic Mucocutaneous - immunology | Interleukin-17 - immunology | Child, Preschool | Molecular Sequence Data | Male | Receptors, Interleukin-17 - genetics | Signal Transduction - genetics | Genes, Recessive | Genes, Dominant | Pedigree | Th17 Cells - immunology | Female | Mutation | Child | Candidiasis | Genetic aspects | Interleukins | Properties | Staphylococcus infections | Immunology | Fungal infections | Mucous membrane | Index Medicus | Human | Nails | Candida | Genetics | Staphylococcus aureus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
by Romain Lévy and Satoshi Okada and Vivien Béziat and Kunihiko Moriya and Caini Liu and Louis Yi Ann Chai and Mélanie Migaud and Fabian Hauck and Amein Al Ali and Cyril Cyrus and Chittibabu Vatte and Turkan Patiroglu and Ekrem Unal and Marie Ferneiny and Nobuyuki Hyakuna and Serdar Nepesov and Matias Oleastro and Aydan Ikinciogullari and Figen Dogu and Takaki Asano and Osamu Ohara and Ling Yun and Erika Della Mina and Didier Bronnimann and Yuval Itan and Florian Gothe and Jacinta Bustamante and Stéphanie Boisson-Dupuis and Natalia Tahuil and Caner Aytekin and Aicha Salhi and Saleh Al Muhsen and Masao Kobayashi and Julie Toubiana and Laurent Abel and Xiaoxia Li and Yildiz Camcioglu and Fatih Celmeli and Christoph Klein and Suzan A. AlKhater and Jean-Laurent Casanova and Anne Puel
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2016, Volume 113, Issue 51, pp. E8277 - E8285
Chronic mucocutaneous candidiasis (CMC) is defined as recurrent or persistent infection of the skin, nails, and/or mucosae with commensal species. The first... 
Genetics | Candidiasis | Immunodeficiency | FUNCTION STAT1 MUTATIONS | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | CHRONIC MUCOCUTANEOUS CANDIDIASIS | INBORN-ERRORS | HYPER-IGE SYNDROME | genetics | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | GAIN-OF-FUNCTION | FUNCTION SIGNAL TRANSDUCER | RECEPTOR-BETA-1 DEFICIENCY | immunodeficiency | candidiasis | DOMINANT GAIN | Cell Membrane | Skin - microbiology | Humans | Open Reading Frames | Child, Preschool | Family Health | Infant | Male | Receptors, Interleukin-17 - genetics | Receptors, Interleukin-17 - deficiency | Bacterial Infections - immunology | HEK293 Cells | Female | Receptors, Interleukin-17 - metabolism | Candidiasis - immunology | Child | Infant, Newborn | Fibroblasts - metabolism | Genome-Wide Association Study | Immunophenotyping | Genes, Recessive | Homozygote | Interleukin-17 - metabolism | T-Lymphocytes - cytology | Pedigree | Candida | Alleles | Mutation | Mycoses - immunology | Leucocytes | Staphylococcus infections | Membranes | Cells | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells
by Lafaille, Fabien G and Pessach, Itai M and Zhang, Shen-Ying and Ciancanelli, Michael J and Herman, Melina and Abhyankar, Avinash and Ying, Shui-Wang and Keros, Sotirios and Goldstein, Peter A and Mostoslavsky, Gustavo and Ordovas-Montanes, Jose and Jouanguy, Emmanuelle and Plancoulaine, Sabine and Tu, Edmund and Elkabetz, Yechiel and Al-Muhsen, Saleh and Tardieu, Marc and Schlaeger, Thorsten M and Daley, George Q and Abel, Laurent and Casanova, Jean-Laurent and Studer, Lorenz and Notarangelo, Luigi D
Nature, ISSN 0028-0836, 11/2012, Volume 491, Issue 7426, pp. 769 - 773
In the course of primary infection with herpes simplex virus 1 (HSV-1), children with inborn errors of toll-like receptor 3 (TLR3) immunity are prone to HSV-1... 
TOLL-LIKE RECEPTOR-3 | TLR3 DEFICIENCY | DOUBLE-STRANDED-RNA | HUMAN ES | PROTECTIVE IMMUNITY | VIRUS ENCEPHALITIS | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | CENTRAL-NERVOUS-SYSTEM | HERPES-SIMPLEX ENCEPHALITIS | RETICULAR THALAMIC NEURONS | Neurons - pathology | Encephalitis, Herpes Simplex - immunology | Humans | Central Nervous System - pathology | Interferons - immunology | Central Nervous System - immunology | Membrane Transport Proteins - deficiency | Neural Stem Cells - immunology | Oligodendroglia - immunology | Astrocytes - immunology | Membrane Transport Proteins - genetics | Toll-Like Receptor 3 - deficiency | Herpesvirus 1, Human - immunology | Cell Differentiation | Toll-Like Receptor 3 - genetics | Induced Pluripotent Stem Cells - cytology | Child | Astrocytes - virology | Central Nervous System - virology | Neurons - virology | Disease Susceptibility | Cell Separation | Induced Pluripotent Stem Cells - virology | Neural Stem Cells - virology | Cells, Cultured | Neurons - immunology | Oligodendroglia - virology | Immunity, Innate | Encephalitis, Herpes Simplex - pathology | Oligodendroglia - pathology | Cell Lineage | Central Nervous System - cytology | Encephalitis, Herpes Simplex - virology | Encephalitis, Herpes Simplex - metabolism | Biomarkers | Herpesvirus 1, Human - pathogenicity | Neurons | Stem cells | Physiological aspects | Toll-like receptors | Virulence (Microbiology) | Research | Health aspects | Herpes simplex virus | Proteins | Epidermal growth factor | Patients | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text LPS-responsive beige-like anchor ( LRBA ) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency
by Alangari, Abdullah, MD and Alsultan, Abdulrahman, MD and Adly, Nouran, BSc and Massaad, Michel J., PhD and Kiani, Iram Shakir, MD and Aljebreen, Abdulrahman, MD and Raddaoui, Emad, MD and Almomen, Abdul-Kareem, MD and Al-Muhsen, Saleh, MD and Geha, Raif S., MD and Alkuraya, Fowzan S., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 481 - 488.e2
Background Clinical immunology has traditionally relied on accurate phenotyping of the patient's immune dysfunction for the identification of a candidate gene... 
Allergy and Immunology | common variable immunodeficiency | autoimmunity | LPS-responsive beige-like anchor (LRBA) | chronic diarrhea | ANTIBODY-DEFICIENCY SYNDROME | B-CELL | TACI | ALLERGY | HUMANS | CHEDIAK-HIGASHI-SYNDROME | IMMUNOLOGY | Humans | Inflammatory Bowel Diseases - immunology | Molecular Sequence Data | Male | Lipopolysaccharides - immunology | Exome - immunology | Young Adult | DNA Mutational Analysis | Base Sequence | Inflammatory Bowel Diseases - genetics | Inflammatory Bowel Diseases - complications | Child | Immunophenotyping | Severe Combined Immunodeficiency - immunology | Severe Combined Immunodeficiency - complications | Severe Combined Immunodeficiency - genetics | Exome - genetics | Phenotype | Pedigree | Adaptor Proteins, Signal Transducing - deficiency | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Family | Consanguinity | Mutation | Medical colleges | Gene mutations | Gastrointestinal diseases | Genes | Immunodeficiency | Genetic research | Genetic aspects | Inflammatory bowel disease | Immune system | Index Medicus | Abridged Index Medicus | Inflammatory bowel diseases | Filtration | Intestine | Phenotyping | Point mutation | Gene mapping | Immunity | Genetic screening
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency
by Dusan Bogunovic and Minji Byun and Larissa A. Durfee and Avinash Abhyankar and Ozden Sanal and Davood Mansouri and Sandra Salem and Irena Radovanovic and Audrey V. Grant and Parisa Adimi and Nahal Mansouri and Satoshi Okada and Vanessa L. Bryant and Xiao-Fei Kong and Alexandra Kreins and Marcela Moncada Velez and Bertrand Boisson and Soheila Khalilzadeh and Ugur Ozcelik and Ilad Alavi Darazam and John W. Schoggins and Charles M. Rice and Saleh Al-Muhsen and Marcel Behr and Guillaume Vogt and Anne Puel and Jacinta Bustamante and Philippe Gros and Jon M. Huibregtse and Laurent Abel and Stéphanie Boisson-Dupuis and Jean-Laurent Casanova
Science, ISSN 0036-8075, 9/2012, Volume 337, Issue 6102, pp. 1684 - 1688
ISG15 is an Interferon (IFN)-α/β—inducible, ubiquitin-like intracellular protein. Its conjugation to various proteins (ISGylation) contributes to antiviral... 
Infectious diseases | Memory interference | Secretion | REPORTS | Alleles | Cell lines | Fibroblasts | Infections | Leukocytes | Natural killer cells | Immunity | INFECTIOUS-DISEASES | GENETICS | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | UBIQUITIN-LIKE PROTEIN | MONOCYTES | CYTOKINE | MUTATIONS | LYMPHOCYTES | Ubiquitins - immunology | Virus Diseases - blood | Virus Diseases - immunology | Ubiquitins - genetics | Humans | Male | Antibodies, Viral - blood | Mycobacterium Infections - blood | Mycobacterium Infections - immunology | Animals | Pedigree | Interferon-gamma - immunology | Mycobacterium Infections - genetics | Interleukin-12 - immunology | Killer Cells, Natural - immunology | Female | T-Lymphocytes - immunology | Mice | Cytokines - genetics | Granulocytes - immunology | Cytokines - immunology | Index Medicus | Human | Mutations | Tuberculosis | Cytokines | Bacteria | Attenuation | Vaccines
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Unbiased targeted next-generation sequencing molecular approach for primary immunodeficiency diseases
by Al-Mousa, Hamoud, MD and Abouelhoda, Mohamed, PhD and Monies, Dorota M., PhD and Al-Tassan, Nada, PhD and Al-Ghonaium, Abdulaziz, MD and Al-Saud, Bandar, MD and Al-Dhekri, Hasan, MD and Arnaout, Rand, MD and Al-Muhsen, Saleh, MD and Ades, Nazema, BN and Elshorbagi, Sahar, MD and Al Gazlan, Sulaiman, MD and Sheikh, Farrukh, MD and Dasouki, Majed, MD and El-Baik, Lina, BSc and Elamin, Tanzeil, MS and Jaber, Amal, BSc and Kheir, Omnia, BPharm and El-Kalioby, Mohamed, MS and Subhani, Shazia, MS and Al Idrissi, Eman, MD and Al-Zahrani, Mofareh, MD and Alhelale, Maryam, MD and Alnader, Noukha, BSc and Al-Otaibi, Afaf, BSc and Kattan, Rana, BSc and Al Abdelrahman, Khalid, BSc and Al Breacan, Muna M., BSc and Bin Humaid, Faisal S., BSc and Wakil, Salma Majid, PhD and Alzayer, Fadi, BSc and Al-Dusery, Haya, BSc and Faquih, Tariq, MS and Al-Hissi, Safa, BSc and Meyer, Brian F., PhD and Hawwari, Abbas, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 137, Issue 6, pp. 1780 - 1787
Background Molecular genetics techniques are an essential diagnostic tool for primary immunodeficiency diseases (PIDs). The use of next-generation sequencing... 
Allergy and Immunology | genetic | mutation | Saudi | next-generation sequencing | Immunodeficiency | targeted | primary immunodeficiency | diagnosis | variants | DEFECTS | IMMUNOLOGY | IDENTIFICATION | ALLERGY | WHOLE-EXOME | MUTATIONS | CAPTURE | Genetic Predisposition to Disease | Genome-Wide Association Study | Genetic Testing | Humans | Computational Biology | Workflow | Genetic Markers | DNA Copy Number Variations | DNA Mutational Analysis | Immunologic Deficiency Syndromes - genetics | High-Throughput Nucleotide Sequencing | Polymorphism, Single Nucleotide | Mutation | Immunologic Deficiency Syndromes - diagnosis | Immunologic Deficiency Syndromes - immunology | Medical colleges | Immunological deficiency syndromes | Genes | Genomics | Studies | Genetic counseling | Disease | Laboratories | Ataxia | Genomes | Patients | Defects | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text IRF8 Mutations and Human Dendritic-Cell Immunodeficiency
by Hambleton, Sophie and Salem, Sandra and Bustamante, Jacinta and Bigley, Venetia and Boisson-Dupuis, Stéphanie and Azevedo, Joana and Fortin, Anny and Haniffa, Muzlifah and Ceron-Gutierrez, Lourdes and Bacon, Chris M and Menon, Geetha and Trouillet, Céline and McDonald, David and Carey, Peter and Ginhoux, Florent and Alsina, Laia and Zumwalt, Timothy J and Kong, Xiao-Fei and Kumararatne, Dinakantha and Butler, Karina and Hubeau, Marjorie and Feinberg, Jacqueline and Al-Muhsen, Saleh and Cant, Andrew and Abel, Laurent and Chaussabel, Damien and Doffinger, Rainer and Talesnik, Eduardo and Grumach, Anete and Duarte, Alberto and Abarca, Katia and Moraes-Vasconcelos, Dewton and Burk, David and Berghuis, Albert and Geissmann, Frédéric and Collin, Matthew and Casanova, Jean-Laurent and Gros, Philippe
The New England Journal of Medicine, ISSN 0028-4793, 07/2011, Volume 365, Issue 2, pp. 127 - 138
Monocytes and dendritic cells regulate adaptive and innate immunity. This study uncovers an association between mutations in the gene encoding interferon... 
RESPONSES | IMMUNITY | MEDICINE, GENERAL & INTERNAL | ICSBP | TUBERCULOSIS | MACROPHAGES | MOUSE | MICE | BINDING | REGULATORY FACTOR-8 | REVEALS | Dendritic Cells - immunology | Humans | Infant | Male | Interferon Regulatory Factors - deficiency | Mycobacterium Infections - immunology | BCG Vaccine - genetics | Genes, Dominant | Leukocytes, Mononuclear - immunology | Mycobacterium Infections - genetics | Adult | Female | Interleukin-12 - biosynthesis | Amino Acid Sequence | Interferon Regulatory Factors - genetics | Models, Molecular | Sequence Alignment | Animals | Antigen-Presenting Cells | Pedigree | Adolescent | BCG Vaccine - immunology | Immunologic Deficiency Syndromes - genetics | Protein Conformation | Mutation | Care and treatment | Gene mutations | Human genome | Immunological deficiency syndromes | Genetic aspects | Interferon | Diagnosis | Research | Transcription factors | Severe combined immunodeficiency | Disease | Transcription | Disseminated infection | Families & family life | Stem cell transplantation | Leukocytes (mononuclear) | Infections | Cell adhesion & migration | Phagocytes | Parents & parenting | Granulocytes | Lymphocytes | Genetic analysis | Combined vaccines | Children | Age | Deoxyribonucleic acid--DNA | Medical research | CD11c antigen | Cytokines | Dendritic cells | BCG | Grants | Hemopoiesis | CD1c antigen | Monocytes | Councils | Antibiotics | Biopsy | Interferon regulatory factor | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
by Okada, Satoshi and Markle, Janet G and Deenick, Elissa K and Mele, Federico and Averbuch, Dina and Lagos, Macarena and Alzahrani, Mohammed and Al-Muhsen, Saleh and Halwani, Rabih and Ma, Cindy S and Wong, Natalie and Soudais, Claire and Henderson, Lauren A and Marzouqa, Hiyam and Shamma, Jamal and Gonzalez, Marcela and Martinez-Barricarte, Rubén and Okada, Chizuru and Avery, Danielle T and Latorre, Daniela and Deswarte, Caroline and Jabot-Hanin, Fabienne and Torrado, Egidio and Fountain, Jeffrey and Belkadi, Aziz and Itan, Yuval and Boisson, Bertrand and Migaud, Mélanie and Lindestam Arlehamn, Cecilia S and Sette, Alessandro and Breton, Sylvain and Cluskey, James and Rossjohn, Jamie and De Villartay, Jean-Pierre and Moshous, Despina and Hambleton, Sophie and Latour, Sylvain and Arkwright, Peter D and Picard, Capucine and Lantz, Olivier and Engelhard, Dan and Kobayashi, Masao and Abel, Laurent and Cooper, Andrea M and Notarangelo, Luigi D and Boisson-Dupuis, Stéphanie and Puel, Anne and Sallusto, Federica and Bustamante, Jacinta and Tangye, Stuart G and Casanova, Jean-Laurent
Science, ISSN 0036-8075, 08/2015, Volume 349, Issue 6248, pp. 606 - 613
Human inborn errors of immunity mediated by the cytokines interleukin-17A and interleukin-17F (IL-17A/F) underlie mucocutaneous candidiasis, whereas inborn... 
IFN-GAMMA IMMUNITY | GENE | MULTIDISCIPLINARY SCIENCES | IL-17 | ORPHAN RECEPTOR | ALPHA | DIFFERENTIATION | CHRONIC MUCOCUTANEOUS CANDIDIASIS | T-CELLS | DEFICIENCY | INBORN-ERRORS | Mycoses | Genetic aspects | Disease susceptibility | Bacteria | Yeast | Mutation | Cytokines | Immune system | Immune systems | Mutations | Errors | Accounting | Candida | Interleukin | Immunity
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text IL-17 enhances the migration of B cells during asthma by inducing CXCL13 chemokine production in structural lung cells
by Al-Kufaidy, Roua, MSc and Vazquez-Tello, Alejandro, PhD and BaHammam, Ahmed S., MD and Hamid, Qutayba, MD, PhD and Al-Muhsen, Saleh, MD and Halwani, Rabih, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 696 - 699.e5
Here, we report a positive correlation between expression of IL-17 cytokines with CXCL13+ cells and B cells numbers in asthmatic airways. IL-17A/F stimulated... 
Allergy and Immunology | IMMUNOLOGY | ALLERGY | BINDING | MHC CLASS-II | EPITOPES | Lung - pathology | Humans | Cells, Cultured | Interleukin-17 - immunology | Male | B-Lymphocytes, Regulatory - immunology | B-Lymphocytes, Regulatory - pathology | Cell Movement - immunology | Asthma - immunology | Th17 Cells - immunology | Adult | Female | Asthma - pathology | Chemokine CXCL13 - immunology | Lung - immunology | Th17 Cells - pathology | Medical colleges | College teachers | B cells | Asthma | Proteins | Immunoglobulins | Statistical analysis | Cytokines | Fibroblasts | Smooth muscle | Software | Kinases | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Glucocorticoid Receptor-Beta Up-Regulation and Steroid Resistance Induction by IL-17 and IL-23 Cytokine Stimulation in Peripheral Mononuclear Cells
by Vazquez-Tello, Alejandro and Halwani, Rabih and Hamid, Qutayba and Al-Muhsen, Saleh
Journal of Clinical Immunology, ISSN 0271-9142, 2/2013, Volume 33, Issue 2, pp. 466 - 478
Most asthmatic patients have well controlled symptoms with regular treatment, but some require much higher doses of inhaled and oral corticosteroids, or in... 
Medical Microbiology | Glucocorticoid resistance | IL-17F | IL-17A | Th-17 cells | IL-4 | Internal Medicine | IL-2 | asthma | GILZ | Biomedicine | Immunology | glucocorticoid receptor-alpha | Infectious Diseases | Glucocorticoid receptor-alpha | Asthma | SYSTEMIC-LUPUS-ERYTHEMATOSUS | INHALED CORTICOSTEROIDS | HETERODIMERIC CYTOKINE | CHRONIC ASTHMA | IMMUNOLOGY | POTENTIAL MECHANISM | IN-VITRO | EPITHELIAL-CELLS | ENDOTHELIAL-CELLS | AIRWAY HYPERRESPONSIVENESS | T-CELLS | Leukocytes, Mononuclear - metabolism | Asthma - metabolism | Leukocytes, Mononuclear - drug effects | Interleukin-6 - genetics | Apoptosis - drug effects | Humans | Middle Aged | Male | Up-Regulation - genetics | Receptors, Glucocorticoid - metabolism | Interleukin-17 - pharmacology | Asthma - drug therapy | Asthma - genetics | Gene Expression Regulation - drug effects | Drug Resistance - genetics | Dexamethasone - pharmacology | Interleukin-23 - pharmacology | Receptors, Glucocorticoid - genetics | Adult | Female | Cell Proliferation - drug effects | Dexamethasone | Cytokines | Analysis | Central nervous system depressants | Steroids | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency
by Sancho-Shimizu, Vanessa and Pérez De Diego, Rebeca and Lorenzo, Lazaro and Halwani, Rabih and Alangari, Abdullah and Israelsson, Elisabeth and Fabrega, Sylvie and Cardon, Annabelle and Maluenda, Jerome and Tatematsu, Megumi and Mahvelati, Farhad and Herman, Melina and Ciancanelli, Michael and Guo, Yiqi and AlSum, Zobaida and Alkhamis, Nouf and Al-Makadma, Abdulkarim S and Ghadiri, Ata and Boucherit, Soraya and Plancoulaine, Sabine and Picard, Capucine and Rozenberg, Flore and Tardieu, Marc and Lebon, Pierre and Jouanguy, Emmanuelle and Rezaei, Nima and Seya, Tsukasa and Matsumoto, Misako and Chaussabel, Damien and Puel, Anne and Zhang, Shen-Ying and Abel, Laurent and Al-Muhsen, Saleh and Casanova, Jean-Laurent
Journal of Clinical Investigation, ISSN 0021-9738, 12/2011, Volume 121, Issue 12, pp. 4889 - 4902
Herpes simplex encephalitis (HSE) is the most common sporadic viral encephalitis of childhood. Autosomal recessive (AR) UNC-93B and TLR3 deficiencies and... 
TOLL-LIKE RECEPTOR-3 | TLR3 DEFICIENCY | MEDICINE, RESEARCH & EXPERIMENTAL | DOMAIN-CONTAINING ADAPTER | PROTECTIVE IMMUNITY | ANTIVIRAL RESPONSES | VIRUS ENCEPHALITIS | SIGNALING PATHWAY | PRIMARY IMMUNODEFICIENCIES | INTERFERON-BETA | NF-KAPPA-B | Humans | Adaptor Proteins, Vesicular Transport - deficiency | Adaptor Proteins, Vesicular Transport - genetics | Child, Preschool | Molecular Sequence Data | Infant | Male | Mutation, Missense | Saudi Arabia | DEAD-box RNA Helicases - physiology | Genes, Dominant | Interferon-alpha - genetics | Encephalitis, Herpes Simplex - genetics | Female | Amino Acid Sequence | Genetic Predisposition to Disease | Genome-Wide Association Study | Adaptor Proteins, Vesicular Transport - physiology | Interferon-alpha - biosynthesis | Genotype | Codon, Nonsense | Genes, Recessive | Genetic Heterogeneity | Herpesvirus 1, Human | Sequence Homology, Amino Acid | Toll-Like Receptor 4 - physiology | Toll-Like Receptor 3 - physiology | Sequence Alignment | Pedigree | Signal Transduction - physiology | Consanguinity | Cellular proteins | Care and treatment | Development and progression | Children | Research | Properties | Health aspects | Herpes simplex encephalitis | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights