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1. Full Text MicroRNA profile in CD8+ T-lymphocytes from HIV-infected individuals: Relationship with antiviral immune response and disease progression
by Egaña-Gorroño, Lander and Guardo, Alberto C and Bargalló, Manel E and Planet, Evarist and Vilaplana, Elisenda and Escribà, Tuixent and Pérez, Iñaki and Gatell, Josep Maria and García, Felipe and Arnedo, Mireia and Plana M, Montserrat and Pineda, Juan Antonio and Sánchez, Eva Recio and De León, Fernando Lozano and Macías, Juan and Palomares, José Carlos and Parra, Manuel and Gómez-Mateos, Jesús and Martínez-Madrid, Onofre Juan and Vera, Francisco and Martínez, Lorena and Miró, José M and Manzardo, Christian and Zamora, Laura and García, Ma. Teresa and Ligero, Carmen and Blanco, José Luis and García-Alcaide, Felipe and Martínez, Esteban and Mallolas, Josep and Gatell, José M and Portilla, Joaquín and Merino, Esperanza and Reus, Sergio and Boix, Vicente and Giner, Livia and Gadea, Carmen and Portilla, Irene and Pampliega, Maria and Díez, Marcos and Rodríguez, Juan Carlos and Sánchez-Payá, Jose and Podzamczer, Daniel and Imaz, Elena Ferrerm Arkaitz and Van Den Eyncle, Evan and Di Yacovo, Silvana and Sumoy, Maria and Gómez, Juan Luis and Rodríguez, Patricia and Alemán, María Remedios and Alonso, María Del Mar and Hernández, María Inmaculada and Díaz-Flores, Felicitas and García, Dácil and Pelazas, Ricardo and Soriano, Vicente and Labarga, Pablo and Barreiro, Pablo and Rivas, Pablo and Blanco, Francisco and Carbonero, Luz Martín and Vispo, Eugenia and Solera, Carmen and Asensi, Victor and Valle, Eulalia and Cartón, José Antonio and Rubio, Rafael and Pulido, Federico and Matarranz, Mariano and Lagarde, Maria and Maestro, Guillermo and Rubio-Martín, Rafael and Iribarren, José Antonio and Arrizabalaga, Julio and Aramburu, María José and Camino, Xabier and Rodríguez-Arrondo, Francisco and Von Wichmann, Miguel Ángel and Tomé, Lidia Pascual and Goenaga, Miguel Ángel and Bustinduy, Ma. Jesús and Galparsoro, Harkaitz Azkune and Ibarguren, Maialen and Aguado, Mirian and Gutiérrez, Félix and Masiá, Mar and López, Cristina and Padilla, Sergio and Navarro, Andrés and Montolio, Fernando and Robledano, Catalina and Colomé, Joan Gregori and Adsuar, Araceli and Pascual, Rafael and Carlos, Federico and Martinez, Maravillas and Muga, Roberto and Tor, Jordi and Sanvisens, Arantza and Berenguer, Juan and ... and HIV Controllers Consortium AIDS and HIV Controllers Consortium of the AIDS Spanish Network
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155245
Background The relationship between host microRNAs (miRNA), viral control and immune response has not yet been elucidated in the field of HIV. The aim of this... 
EFFECTOR | T-CELL DIFFERENTIATION | ACTIVATION | BIOINFORMATICS | MEMORY | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | CD4(+) | ABSENCE | EXPRESSION | MIR-181A | Anti-HIV Agents - pharmacology | Reproducibility of Results | HIV Infections - genetics | Humans | Middle Aged | Male | MicroRNAs - metabolism | Gene Expression Profiling | Disease Progression | Immunity - drug effects | HIV Infections - immunology | HIV Infections - pathology | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy | MicroRNAs - genetics | CD8-Positive T-Lymphocytes - immunology | Real-Time Polymerase Chain Reaction | Complications and side effects | Care and treatment | MicroRNA | Analysis | Influence | Cellular signal transduction | Research | HIV infection | Enrichment | Controllers | Antiretroviral drugs | Immune response | Control methods | CD8 antigen | Genes | MiRNA | Lymphocytes T | CD3 antigen | T cell receptors | Gene expression | CD28 antigen | Ribonucleic acid--RNA | Disease control | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Transduction | Apoptosis | Immune system | RNA | Ribonucleic acid | AIDS | HIV | Acquired immune deficiency syndrome | Human immunodeficiency virus
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2. Full Text Abstracts of the HIV Research for Prevention Meeting, HIVR4P, 21-25 October, 2018, Madrid
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2018, Volume 34, Issue S1, pp. 1 - 407
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3. Full Text Correction: Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization
by Guardo, Alberto C and Gómez, Carmen Elena and Díaz-Brito, Vicens and Pich, Judit and Arnaiz, Joan Albert and Perdiguero, Beatriz and García-Arriaza, Juan and González, Nuria and Sorzano, Carlos O S and Jiménez, Laura and Jiménez, José Luis and Muñoz-Fernández, María Ángeles and Gatell, José M and Alcamí, José and Esteban, Mariano and de Quirós, Juan Carlos López Bernaldo and García, Felipe and Plana, Montserrat and RISVAC02boost study and for the RISVAC02boost study
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 4, p. e0195915
[This corrects the article DOI: 10.1371/journal.pone.0186602.]. 
Immunization | Immune response | Vaccines | Human immunodeficiency virus--HIV | Human immunodeficiency virus | HIV
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4. Full Text Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization
by Guardo, Alberto C and Gómez, Carmen Elena and Díaz-Brito, Vicens and Pich, Judit and Arnaiz, Joan Albert and Perdiguero, Beatriz and García-Arriaza, Juan and González, Nuria and Sorzano, Carlos O. S and Jiménez, Laura and Jiménez, José Luis and Muñoz-Fernández, María Ángeles and Gatell, José M and Alcamí, José and Esteban, Mariano and Bernaldo de Quirós, Juan Carlos López and García, Felipe and Plana, Montserrat and RISVAC02boost Study and RISVAC02boost study and for the RISVAC02boost study
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, p. e0186602
Background We have previously shown that an HIV vaccine regimen including three doses of HIV-modified vaccinia virus Ankara vector expressing HIV-1 antigens... 
HIV/AIDS | TRIAL | ANKARA VACCINES | IMMUNOGENICITY | MEMORY | DNA | MULTIDISCIPLINARY SCIENCES | POXVIRUS VECTORS | HUMANS | VIRUS-LIKE PARTICLES | NYVAC | HIV Antibodies - blood | Enzyme-Linked Immunosorbent Assay | Humans | AIDS Vaccines - immunology | Healthy Volunteers | AIDS Vaccines - adverse effects | CD4-Positive T-Lymphocytes - immunology | Antibodies, Neutralizing - immunology | HIV-1 - immunology | Flow Cytometry | Immunization, Secondary | Placebos | CD8-Positive T-Lymphocytes - immunology | Physiological aspects | AIDS vaccines | Immunization | Safety and security measures | Immune response | Research | Bioengineering | CD8 antigen | Antibodies | Clinical trials | Viruses | Lymphocytes T | Genomes | Vaccines | Biomedical materials | Immunology | Gag protein | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Safety | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Binding | Antigens | Durability | Immune response (humoral) | CD4 antigen | Infectious diseases | Immunogenicity | Neutralizing | γ-Interferon | Interferon | Glycoprotein gp120 | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
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5. Full Text Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers
by Benito, José M and Ortiz, María C and León, Agathe and Sarabia, Luis A and Ligos, José M and Montoya, María and Garcia, Marcial and Ruiz-Mateos, Ezequiel and Palacios, Rosario and Cabello, Alfonso and Restrepo, Clara and Rodriguez, Carmen and del Romero, Jorge and Leal, Manuel and Muñoz-Fernández, María A and Alcamí, José and García, Felipe and Górgolas, Miguel and Rallón, Norma and ECRIS Integrated Spanish AIDS Res and ECRIS integrated in the Spanish AIDS Research Network and On behalf of ECRIS integrated in the Spanish AIDS Research Network
BMC Medicine, ISSN 1741-7015, 02/2018, Volume 16, Issue 1, pp. 30 - 12
Background: Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss.... 
CD4 T-cell loss | T-cell homeostatic parameters | CD8 exhaustion | Class modeling | Elite controllers | NATURAL VIRAL SUPPRESSORS | ACTIVATION | T cell homeostatic parameters | ATHEROSCLEROSIS | FUNCTIONAL CURE | ANTIRETROVIRAL THERAPY | MECHANISMS | MEDICINE, GENERAL & INTERNAL | HIV-INFECTION | MEMORY STEM-CELLS | CD4 T cell loss | ABSENCE | IMMUNODEFICIENCY | T cells | Research
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6. Full Text Novel association of five HLA alleles with HIV-1 progression in Spanish long-term non progressor patients
by de Arellano, ER and Diez-Fuertes, F and Aguilar, F and Tarazona, HED and Sanchez-Lara, S and Lao, Y and Vicario, JL and Garcia, F and Gonzalez-Garcia, J and Pulido, F and Gutierrez-Rodero, FPL and Moreno, S and Iribarren, JA and Viciana, P and Vilches, C and Ramos, M and Capa, L and Alcami, J and Del Val, M
PLOS ONE, ISSN 1932-6203, 08/2019, Volume 14, Issue 8, p. e0220459
Certain host genetic variants, especially in the human leucocyte antigen (HLA) region, are associated with different progression of HIV-1-induced diseases and... 
REPLICATION | CLASS-I ALLELES | NONPROGRESSION | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | IMMUNODEFICIENCY-VIRUS TYPE-1 | AIDS | INFECTION | COHORT | POLYMORPHISM | GENETIC RESTRICTION | Histocompatibility antigens | HLA histocompatibility antigens | Development and progression | Genetic aspects | Single nucleotide polymorphisms | HIV infection | Health aspects | Health care | CC chemokine receptors | Positive selection | Cytotoxicity | Population studies | Infections | Genomes | Single-nucleotide polymorphism | Leukocytes | Nucleotides | Homozygosity | Population genetics | Immunology | CCR2 protein | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Genetic analysis | Population | Genetic factors | Antigens | Phenotypes | Studies | Genetic variance | Infectious diseases | Hospitals | Gene frequency | Alleles | Histocompatibility antigen HLA | Monocyte chemoattractant protein 1 | Acquired immune deficiency syndrome | HIV | Human immunodeficiency virus
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7. Full Text Neoflavonoids as inhibitors of HIV-1 replication by targeting the Tat and NF-κB pathways
by Olmedo, Dionisio A and López-Pérez, José Luis and Del Olmo, Esther and Bedoya, Luis M and Sancho, Rocío and Alcamí, José and Muñoz, Eduardo and San Feliciano, Arturo and Gupta, Mahabir P
Molecules, ISSN 1420-3049, 02/2017, Volume 22, Issue 2, pp. 321 - 321
Twenty-eight neoflavonoids have been prepared and evaluated in vitro against HIV-1. Antiviral activity was assessed on MT-2 cells infected with viral clones... 
Neoflavonoids | Anti-HIV activity | Tat protein | AIDS | NF-κB inhibition | 4-phenyl-chromen-one | Anti-HIV Agents - pharmacology | Virus Replication - drug effects | HIV-1 - drug effects | HIV Infections - virology | Humans | NF-kappa B - metabolism | Microbial Sensitivity Tests | Anti-HIV Agents - chemistry | Signal Transduction - drug effects | HIV Infections - drug therapy | Flavonoids - isolation & purification | Flavonoids - pharmacology | Molecular Structure | Anti-HIV Agents - isolation & purification | Flavonoids - chemistry | HIV Infections - metabolism | tat Gene Products, Human Immunodeficiency Virus - metabolism | Reporter gene | Transcription | Human immunodeficiency virus--HIV | Antiviral activity | Replication | Inhibition | In vitro methods and tests | neoflavonoids | anti-HIV activity
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8. Full Text Use of RT-Defective HIV Virions: New Tool to Evaluate Specific Response in Chronic Asymptomatic HIV-Infected Individuals
by Guardo, Alberto Crespo and Álvarez-Fernández, Carmen and Arberas, Hodei and García-Pérez, Javier and García, Felipe and Bargalló, Manuel Enric and Maleno, María José and Gatell, José María and Mothe, Beatriz and Alcami, José and Sánchez-Palomino, Sonsoles and Plana, Montserrat
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58927
Background: Generation of new reagents that can be used to screen or monitor HIV-1-specific responses constituted an interesting field in the development of... 
IMMUNITY | T-CELL RESPONSES | DENDRITIC CELLS | PEPTIDE SETS | MULTIDISCIPLINARY SCIENCES | ALVAC-HIV | IMMUNODEFICIENCY-VIRUS TYPE-1 | HLA-B | PROTEINS | VIRAL REPLICATION | SUBTYPE-A | Humans | Middle Aged | HIV Reverse Transcriptase - genetics | Male | Asymptomatic Diseases | Viral Vaccines - adverse effects | Leukocytes, Mononuclear - virology | Microbial Viability - immunology | CD4-Positive T-Lymphocytes - immunology | Young Adult | HIV Infections - immunology | HIV-1 - physiology | Time Factors | Leukocytes, Mononuclear - immunology | Virion - enzymology | Adult | Female | Safety | CD4-Positive T-Lymphocytes - virology | Virion - immunology | Virion - physiology | Sex Characteristics | Viral Load - immunology | HIV Reverse Transcriptase - metabolism | HIV-1 - immunology | CD8-Positive T-Lymphocytes - virology | Alleles | HIV-1 - enzymology | CD8-Positive T-Lymphocytes - immunology | Viral Vaccines - immunology | AIDS vaccines | Cytokines | HIV testing | Development and progression | HIV patients | HIV (Viruses) | T cells | HIV infection | Flow cytometry | Peptides | Clinical trials | Viruses | Activation | Lymphocytes T | Vaccines | Defects | Envelopes | CD69 antigen | Surface activation | Cell activation | Gag protein | Acquired immune deficiency syndrome--AIDS | Cryopreservation | Lymphocytes | Prototypes | CD38 antigen | Virions | Human immunodeficiency virus--HIV | Low cost | Peripheral blood mononuclear cells | Enzyme-linked immunosorbent assay | Markers | T cell receptors | CD4 antigen | Cytometry | Nef protein | Immunogenicity | Gene frequency | γ-Interferon | Reagents | Interferon | Histocompatibility antigen HLA | VIH (Virus) | Immunologia | Immunology | Viral vaccines | Vacunes antivíriques | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
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9. Full Text Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy
by Betancor, Gilberto and Garriga, César and Puertas, Maria C and Nevot, María and Anta, Lourdes and Blanco, José L and Pérez-Elías, M J and de Mendoza, Carmen and Martínez, Miguel A and Martinez-Picado, Javier and Menéndez-Arias, Luis and Iribarren, Joś Antonio and Caballero, Estrella and Ribera, Esteban and Llibre, Josep Maria and Clotet, Bonaventura and Jaén, Angels and Dalmau, David and Gatell, Joś María and Peraire, Joaquín and Vidal, Francesc and Vidal, Carmen and Riera, Melchor and Córdoba, Juan and Aldeguer, José López and Galindo, María José and Gutiérrez, Félix and Álvarez, Marta and García, Federico and Pérez-Romero, Pilar and Viciana, Pompeyo and Leal, Manuel and Palomares, José Carlos and Pineda, Juan Antonio and Viciana, Isabel and Santos, Jesús and Rodríguez, Patricia and Luis, Juan and Sirvent, Gómez and Gutiérrez, Carolina and Moreno, Santiago and Pérez-Olmeda, Mayte and Alcamí, José and Rodríguez, Carmen and del Romero, Jorge and Cañizares, Angelina and Pedreira, José and Miralles, Celia and Ocampo, Antonio and Morano, Luis and Aguilera, Antonio and Garrido, Carolina and Manuzza, Gustavo and Poveda, Eva and Soriano, Vicente and Resistance Platform Spanish AIDS R and Resistance Platform of the Spanish AIDS Research Network (ResRIS) and for the Resistance Platform of the Spanish AIDS Research Network (ResRIS)
Retrovirology, ISSN 1742-4690, 08/2012, Volume 9, Issue 1, pp. 68 - 68
Background: Thymidine analogue resistance mutations (TAMs) selected under treatment with nucleoside analogues generate two distinct genotypic profiles in the... 
NUCLEOTIDE ANALOGS | NUCLEOSIDE | PRIMER UNBLOCKING | VIROLOGY | DNA | AMINO-ACID SUBSTITUTIONS | ANTIRETROVIRAL THERAPY | DRUG SUSCEPTIBILITY | CONFERS ZIDOVUDINE | H DOMAIN | CONNECTION DOMAIN | Anti-HIV Agents - pharmacology | Humans | Drug Resistance, Viral | Molecular Sequence Data | Deoxycytidine - pharmacology | HIV Reverse Transcriptase - genetics | Mutation, Missense | Anti-HIV Agents - administration & dosage | Tenofovir | HIV-1 - isolation & purification | Treatment Failure | Emtricitabine | Adenine - analogs & derivatives | HIV-1 - drug effects | Deoxycytidine - administration & dosage | HIV Infections - virology | Selection, Genetic | Adenine - pharmacology | HIV-1 - genetics | Sequence Analysis, DNA | Adenine - administration & dosage | HIV Reverse Transcriptase - metabolism | Organophosphonates - administration & dosage | Organophosphonates - pharmacology | HIV Infections - drug therapy | Deoxycytidine - analogs & derivatives | Drug resistance in microorganisms | Highly active antiretroviral therapy | Care and treatment | Reverse transcriptase | Gene mutations | DNA polymerases | Genetic aspects | Ribonuclease | Drug resistance | HIV (Viruses) | Zidovudine | Genetic polymorphisms
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10. Full Text Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02)
by García, Felipe and Bernaldo de Quirós, Juan Carlos López and Gómez, Carmen E and Perdiguero, Beatriz and Nájera, Jose L and Jiménez, Victoria and García-Arriaza, Juan and Guardo, Alberto C and Pérez, Iñaki and Díaz-Brito, Vicens and Conde, Matilde Sánchez and González, Nuria and Alvarez, Amparo and Alcamí, José and Jiménez, José Luis and Pich, Judit and Arnaiz, Joan Albert and Maleno, María J and León, Agathe and Muñoz-Fernández, María Angeles and Liljeström, Peter and Weber, Jonathan and Pantaleo, Giuseppe and Gatell, José M and Plana, Montserrat and Esteban, Mariano
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 46, pp. 8309 - 8316
Highlights ► Safety and immunogenicity of HIV/AIDS MVA-B. ► This first phase I trial with candidate MVA-B in healthy volunteers showed that this immunogen was... 
Allergy and Immunology | HIV | MVA-B | Vaccine | HIV Antibodies - blood | Humans | Middle Aged | AIDS Vaccines - immunology | Viral Proteins - immunology | Male | Vaccines, Synthetic - immunology | Human Experimentation | Vaccinia virus - genetics | AIDS Vaccines - adverse effects | Drug Carriers | Young Adult | Leukocytes, Mononuclear - immunology | Adult | Female | Placebos - administration & dosage | Double-Blind Method | Vaccines, Synthetic - genetics | Cytokines - secretion | Viral Proteins - genetics | Enzyme-Linked Immunospot Assay | Injections, Intramuscular | HIV-1 - genetics | HIV-1 - immunology | Adolescent | AIDS Vaccines - genetics | Vaccines, Synthetic - administration & dosage | AIDS Vaccines - administration & dosage | Genetic Vectors | Antigens | AIDS vaccines | Viral proteins | AIDS (Disease) | Clinical trials | Product development | HIV (Viruses) | T cells | Studies | Smallpox | Vaccines | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV
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11. Full Text 3-phenylcoumarins as inhibitors of HIV-1 replication
by Olmedo, Dionisio and Sancho, Rocío and Bedoya, Luis M and López-Pérez, José L and Del Olmo, Esther and Muñoz, Eduardo and Alcamí, José and Gupta, Mahabir P and Feliciano, Arturo San
Molecules, ISSN 1420-3049, 08/2012, Volume 17, Issue 8, pp. 9245 - 9257
We have synthesized fourteen 3-phenylcoumarin derivatives and evaluated their anti-HIV activity. Antiviral activity was assessed on MT-2 cells infected with... 
Anti-HIV activity | Tat protein | AIDS | NF-κB inhibition | 3-phenylcoumarins | CONVENIENT SYNTHESIS | 4-PHENYLCOUMARINS | NF-kappa B inhibition | SERIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | anti-HIV activity | CHEMISTRY, MULTIDISCIPLINARY | POTENT | TREE | PROTEASE | COUMARIN DERIVATIVES | Anti-HIV Agents - pharmacology | Cell Line | Transcription, Genetic - drug effects | Virus Replication - drug effects | NF-kappa B - antagonists & inhibitors | HIV-1 - drug effects | Humans | Anti-HIV Agents - chemical synthesis | Luciferases - genetics | Coumarins - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | HIV-1 - physiology | Coumarins - chemical synthesis | Inhibitory Concentration 50 | tat Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | HeLa Cells | Genes, Reporter | Luciferases - biosynthesis | NF- κ B inhibition
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12. Full Text Surface‐Supported Robust 2D Lanthanide‐Carboxylate Coordination Networks
by Urgel, José I and Cirera, Borja and Wang, Yang and Auwärter, Willi and Otero, Roberto and Gallego, José M and Alcamí, Manuel and Klyatskaya, Svetlana and Ruben, Mario and Martín, Fernando and Miranda, Rodolfo and Ecija, David and Barth, Johannes V
Small, ISSN 1613-6810, 12/2015, Volume 11, Issue 47, pp. 6358 - 6364
Lanthanide‐based metal–organic compounds and architectures are promising systems for sensing, heterogeneous catalysis, photoluminescence, and magnetism.... 
coordination networks, self‐assembly | metal–organic coordination networks | surface coordination chemistry | lanthanides | coordination networks, self-assembly | metal-organic coordination networks | POLYMERS | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | ACID | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | TOTAL-ENERGY CALCULATIONS | CHEMISTRY, MULTIDISCIPLINARY | FRAMEWORKS | QUARTET | PHOTOEMISSION | DYNAMICS | METAL | Rare earth metals | Density functionals | Heterogeneous catalysis | Magnetism
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