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PLoS ONE, ISSN 1932-6203, 04/2019, Volume 14, Issue 4
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 07/2015, Volume 80, Issue 13, pp. 6545 - 6552
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 03/2018, Volume 9, Issue 3, pp. 159 - 160
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2015, Volume 54, Issue 44, pp. 13041 - 13044
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2012, Volume 12, Issue 7, pp. 671 - 671
Journal Article
PLOS ONE, ISSN 1932-6203, 04/2019, Volume 14, Issue 4, p. e0216008
Imidazolium salts are shown to catalyze the rapid room temperature reaction of indoles or naphthol with aldehydes to provide bis(indolyl) methanes or... 
ACID | BISINDOLYLMETHANES | MULTIDISCIPLINARY SCIENCES | EFFICIENT SYNTHESIS | BACTERIUM | IONIC LIQUID | ARSINDOLINE B | INDOLE ALKALOIDS | DERIVATIVES | BIS | MARINE NATURAL-PRODUCTS | Methane | Additives | Salts | Aldehydes | Substrates | Chemistry | Imidazole | Dichloromethane | Naphthol | Methylene chloride | Catalysis | Indoles | Pharmaceutical sciences
Journal Article
Chemistry (Weinheim an der Bergstrasse, Germany), ISSN 0947-6539, 10/2017, Volume 23, Issue 58, pp. 14434 - 14438
Reduction of phosphine oxides to the corresponding phosphine represents the most straightforward method to prepare these valuable reagents. However, existing... 
Synthetic methods | Phosphine oxides | Disiloxane | Chemoselective methods | Silane reductions
Journal Article
Nature Communications, 2018, Volume 9, Issue 1
Journal Article
Acta Crystallographica Section C, ISSN 2053-2296, 08/2019, Volume 75, Issue 8, pp. 1031 - 1035
Mycobacterium tuberculosis ( Mtb ), the principal etiological agent of tuberculosis (TB), infects over one‐quarter of humanity and is now the leading cause of... 
synthesis | crystal structure | macozinone | drug sensitive | tuberculosis | drug resistant | DIASTEREOSELECTIVE SYNTHESIS | BENZOTHIAZINONES | CRYSTALLOGRAPHY | CHEMISTRY, MULTIDISCIPLINARY | Medical research | Nuclear magnetic resonance--NMR | Infectious diseases | Tuberculosis | Etiology | Crystallography | Crystal structure | Structural analysis
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 08/2013, Volume 78, Issue 15, pp. 7470 - 7481
MbtA catalyzes the first committed step of mycobactin biosynthesis in Mycobacterium tuberculosis (Mtb) and is responsible for the incorporation of salicylic... 
MYCOBACTERIUM-TUBERCULOSIS | DOMAIN | NONRIBOSOMAL PEPTIDE SYNTHETASE | FLUORESCENCE POLARIZATION | GENE-CLUSTER | ANTITUBERCULAR AGENTS | ANALOGS | CHEMISTRY, ORGANIC | IRON ACQUISITION | ANTIBACTERIAL AGENTS | DISCOVERY | Antitubercular Agents - chemical synthesis | Antitubercular Agents - chemistry | Nucleosides - chemical synthesis | Benzoxazines - chemical synthesis | Quinolones - pharmacology | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Mycobacterium tuberculosis - drug effects | Siderophores - biosynthesis | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Quinolones - chemistry | Quinolones - chemical synthesis | Enzyme Inhibitors - chemistry | Nucleosides - pharmacology | Molecular Structure | Chromones - pharmacology | Benzoxazines - chemistry | Nucleosides - chemistry | Biocatalysis | Sulfonamides - chemistry | Antitubercular Agents - pharmacology | Enzyme Inhibitors - pharmacology | Ligases - metabolism | Models, Molecular | Sulfonamides - pharmacology | Chromones - chemistry | Sulfonamides - chemical synthesis | Ligases - antagonists & inhibitors | Mycobacterium tuberculosis - enzymology | Benzoxazines - pharmacology | Chromones - chemical synthesis | Thermal properties | Mycobacterium tuberculosis | Analysis | Conformational analysis | Molecular dynamics | Research | Chemical properties | Enzyme kinetics | Methods
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 08/2017, Volume 82, Issue 15, pp. 7806 - 7819
Amiclenomycin (ACM) is a chemically unstable antibiotic with selective activity against Mycobacterium tuberculosis (Mtb) due to mechanism-based inhibition of... 
MYCOBACTERIUM-TUBERCULOSIS | SYNTHASE | INACTIVATION | N-BOC GROUP | ACID AMINOTRANSFERASE | PEPTIDES | BIOTIN BIOSYNTHESIS | NATURAL-PRODUCTS | CHEMISTRY, ORGANIC | DEPROTECTION | AMICLENOMYCIN | Usage | Ring formation (Chemistry) | Chemical properties | Chemical synthesis | Amino compounds
Journal Article
Angewandte Chemie, ISSN 0044-8249, 10/2015, Volume 127, Issue 44, p. 13233
  The Mitsunobu reaction is renowned for its mild reaction conditions and broad substrate tolerance, but has limited utility in process chemistry and... 
Journal Article
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