Stroke, ISSN 0039-2499, 10/2019, Volume 50, Issue 10, pp. 2738 - 2744
BACKGROUND AND PURPOSE—Clazosentan, an endothelin receptor antagonist, has been shown to reduce angiographic vasospasm and vasospasm-related morbidity after...
METAANALYSIS | DELAYED CEREBRAL-ISCHEMIA | Glasgow Outcome Scale | COGNITIVE IMPAIRMENT | vasospasm | clazosentan | delayed cerebral ischemia | ENDOTHELIN-RECEPTOR ANTAGONISTS | CLINICAL NEUROLOGY | INFARCTION | subarachnoid hemorrhage | PREDICTORS | DOUBLE-BLIND | ANGIOGRAPHIC VASOSPASM | PERIPHERAL VASCULAR DISEASE | COMPLICATIONS | QUALITY-OF-LIFE | Prevention | Cerebrovascular spasm | Subarachnoid hemorrhage | Antihypertensive drugs | Physiological aspects | Dosage and administration | Drug therapy
METAANALYSIS | DELAYED CEREBRAL-ISCHEMIA | Glasgow Outcome Scale | COGNITIVE IMPAIRMENT | vasospasm | clazosentan | delayed cerebral ischemia | ENDOTHELIN-RECEPTOR ANTAGONISTS | CLINICAL NEUROLOGY | INFARCTION | subarachnoid hemorrhage | PREDICTORS | DOUBLE-BLIND | ANGIOGRAPHIC VASOSPASM | PERIPHERAL VASCULAR DISEASE | COMPLICATIONS | QUALITY-OF-LIFE | Prevention | Cerebrovascular spasm | Subarachnoid hemorrhage | Antihypertensive drugs | Physiological aspects | Dosage and administration | Drug therapy
Journal Article
Journal of Neurosurgery, ISSN 0022-3085, 01/2013, Volume 118, Issue 1, pp. 74 - 83
Object. The object of this study was to assess outcomes in patients with arteriovenous malformations (AVMs) treated by Gamma Knife stereotactic radiosurgery...
Stereotactic radiosurgery | Spetzler-Martin grading system | Vascular disorders | Surgery | Arteriovenous malformation | Gamma knife | arteriovenous malformation | MANAGEMENT | SPECIAL WRITING GROUP | FOLLOW-UP | RISK | NATURAL-HISTORY | HEALTH-CARE PROFESSIONALS | vascular disorders | CLINICAL NEUROLOGY | stereotactic radiosurgery | GRADING SYSTEM | RECOMMENDATIONS | AMERICAN-STROKE-ASSOCIATION | COMPLICATIONS | Gamma Knife | surgery
Stereotactic radiosurgery | Spetzler-Martin grading system | Vascular disorders | Surgery | Arteriovenous malformation | Gamma knife | arteriovenous malformation | MANAGEMENT | SPECIAL WRITING GROUP | FOLLOW-UP | RISK | NATURAL-HISTORY | HEALTH-CARE PROFESSIONALS | vascular disorders | CLINICAL NEUROLOGY | stereotactic radiosurgery | GRADING SYSTEM | RECOMMENDATIONS | AMERICAN-STROKE-ASSOCIATION | COMPLICATIONS | Gamma Knife | surgery
Journal Article
Lancet, The, ISSN 0140-6736, 2017, Volume 389, Issue 10069, pp. 603 - 611
Summary Background Intraventricular haemorrhage is a subtype of intracerebral haemorrhage, with 50% mortality and serious disability for survivors. We aimed to...
Internal Medicine | INTRACEREBRAL HEMORRHAGE | MEDICINE, GENERAL & INTERNAL | UPDATE | PLASMINOGEN-ACTIVATOR | RESOLUTION | BLOOD | Stroke (Disease) | Clinical trials | United Kingdom | Nervous system diseases | Drug therapy | Mortality | Care and treatment | Analysis | Intensive care | Stroke | Patients | Hemorrhage | Medical treatment
Internal Medicine | INTRACEREBRAL HEMORRHAGE | MEDICINE, GENERAL & INTERNAL | UPDATE | PLASMINOGEN-ACTIVATOR | RESOLUTION | BLOOD | Stroke (Disease) | Clinical trials | United Kingdom | Nervous system diseases | Drug therapy | Mortality | Care and treatment | Analysis | Intensive care | Stroke | Patients | Hemorrhage | Medical treatment
Journal Article
Journal of Neurosurgery, ISSN 0022-3085, 09/2013, Volume 119, Issue 3, pp. 821 - 822
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2016, Volume 15, Issue 12, pp. 1228 - 1237
Summary Background Craniotomy, according to the results from trials, does not improve functional outcome after intracerebral haemorrhage. Whether minimally...
Neurology | Cerebral Hemorrhage - drug therapy | Follow-Up Studies | Outcome Assessment (Health Care) | Humans | Middle Aged | Cerebral Hemorrhage - mortality | Cerebral Hemorrhage - surgery | Male | Tissue Plasminogen Activator - administration & dosage | Combined Modality Therapy | Thrombectomy - adverse effects | Tissue Plasminogen Activator - adverse effects | Fibrinolytic Agents - adverse effects | Fibrinolytic Agents - pharmacology | Postoperative Hemorrhage - etiology | Tissue Plasminogen Activator - pharmacology | Thrombectomy - methods | Surgery, Computer-Assisted | Female | Aged | Fibrinolytic Agents - administration & dosage | Minimally Invasive Surgical Procedures | Brain | Evacuation of civilians | Tissue plasminogen activator | Surgery | Injuries | Biometry | Coma | Stroke | Intensive care | Pragmatism | Mortality | Blood pressure | Laparoscopy | Hemorrhage | Patients
Neurology | Cerebral Hemorrhage - drug therapy | Follow-Up Studies | Outcome Assessment (Health Care) | Humans | Middle Aged | Cerebral Hemorrhage - mortality | Cerebral Hemorrhage - surgery | Male | Tissue Plasminogen Activator - administration & dosage | Combined Modality Therapy | Thrombectomy - adverse effects | Tissue Plasminogen Activator - adverse effects | Fibrinolytic Agents - adverse effects | Fibrinolytic Agents - pharmacology | Postoperative Hemorrhage - etiology | Tissue Plasminogen Activator - pharmacology | Thrombectomy - methods | Surgery, Computer-Assisted | Female | Aged | Fibrinolytic Agents - administration & dosage | Minimally Invasive Surgical Procedures | Brain | Evacuation of civilians | Tissue plasminogen activator | Surgery | Injuries | Biometry | Coma | Stroke | Intensive care | Pragmatism | Mortality | Blood pressure | Laparoscopy | Hemorrhage | Patients
Journal Article
Neurosurgery, ISSN 0148-396X, 09/2019
Subarachnoid hemorrhage (SAH) is most commonly caused by a ruptured vascular lesion. A significant number of patients presenting with SAH have no identifiable...
Journal Article
Journal of Neurosurgery, ISSN 0022-3085, 06/2019, Volume 130, Issue 6, pp. 1984 - 1991
OBJECTIVEThe authors sought to evaluate whether a sustained systemic inflammatory response was associated with shunt-dependent hydrocephalus following...
Journal Article
The Lancet, ISSN 0140-6736, 03/2019, Volume 393, Issue 10175, pp. 1021 - 1032
Acute stroke due to supratentorial intracerebral haemorrhage is associated with high morbidity and mortality. Open craniotomy haematoma evacuation has not been...
STROKE | MEDICINE, GENERAL & INTERNAL | THERAPY | METAANALYSIS | INITIAL CONSERVATIVE TREATMENT | TISSUE-PLASMINOGEN ACTIVATOR | FEASIBILITY | PERFORMANCE | HEMATOMAS | ASPIRATION | FACTOR-VII | Minimally Invasive Surgical Procedures - methods | Minimally Invasive Surgical Procedures - adverse effects | Humans | Middle Aged | Intention to Treat Analysis | Thrombolytic Therapy - methods | Cerebral Hemorrhage - surgery | Female | Male | Treatment Outcome | Aged | Thrombolytic Therapy - adverse effects | Evacuation of civilians | Canada | Analysis | Surgery | United Kingdom | Australia | Maryland | Coma | Health care | Brain | Intensive care | Medical services | Clinical trials | Infections | Hemorrhage | Bleeding | Regression models | Randomization | Motivation | Safety | Drug dosages | Medical personnel | Stroke | Sensitivity analysis | Statistical analysis | Effectiveness | Adjustment | Mortality | Medical instruments | Laparoscopy | Stability analysis | Regression analysis | Patients | Thrombolysis | Morbidity | Neurological diseases | Studies | Hematoma
STROKE | MEDICINE, GENERAL & INTERNAL | THERAPY | METAANALYSIS | INITIAL CONSERVATIVE TREATMENT | TISSUE-PLASMINOGEN ACTIVATOR | FEASIBILITY | PERFORMANCE | HEMATOMAS | ASPIRATION | FACTOR-VII | Minimally Invasive Surgical Procedures - methods | Minimally Invasive Surgical Procedures - adverse effects | Humans | Middle Aged | Intention to Treat Analysis | Thrombolytic Therapy - methods | Cerebral Hemorrhage - surgery | Female | Male | Treatment Outcome | Aged | Thrombolytic Therapy - adverse effects | Evacuation of civilians | Canada | Analysis | Surgery | United Kingdom | Australia | Maryland | Coma | Health care | Brain | Intensive care | Medical services | Clinical trials | Infections | Hemorrhage | Bleeding | Regression models | Randomization | Motivation | Safety | Drug dosages | Medical personnel | Stroke | Sensitivity analysis | Statistical analysis | Effectiveness | Adjustment | Mortality | Medical instruments | Laparoscopy | Stability analysis | Regression analysis | Patients | Thrombolysis | Morbidity | Neurological diseases | Studies | Hematoma
Journal Article
Journal of Neurosurgery, ISSN 0022-3085, 12/2013, Volume 119, Issue 6, pp. 1611 - 1619
Object. Aneurysmal subarachnoid hemorrhage (aSAH) predisposes to delayed neurological deficits, including stroke and cognitive and neuropsychological...
Cerebral vasospasm | Inflammation | Heparin | Subarachnoid hemorrhage | Vascular disorders | ENOXAPARIN | SURGERY | INDUCED THROMBOCYTOPENIA | MONONUCLEAR-CELLS | KAPPA-B | cerebral vasospasm | vascular disorders | CLINICAL NEUROLOGY | heparin | INFARCTION | inflammation | subarachnoid hemorrhage | DOUBLE-BLIND | ANGIOGRAPHIC VASOSPASM | UNFRACTIONATED HEPARIN
Cerebral vasospasm | Inflammation | Heparin | Subarachnoid hemorrhage | Vascular disorders | ENOXAPARIN | SURGERY | INDUCED THROMBOCYTOPENIA | MONONUCLEAR-CELLS | KAPPA-B | cerebral vasospasm | vascular disorders | CLINICAL NEUROLOGY | heparin | INFARCTION | inflammation | subarachnoid hemorrhage | DOUBLE-BLIND | ANGIOGRAPHIC VASOSPASM | UNFRACTIONATED HEPARIN
Journal Article
Neurocritical Care, ISSN 1541-6933, 2/2019, Volume 30, Issue 1, pp. 88 - 97
Nimodipine is the only drug approved in the treatment of aneurysmal subarachnoid hemorrhage (aSAH) in many countries. EG-1962, a product developed using the...
Neurology | Cerebral aneurysm | Delayed cerebral ischemia | Extended release | Medicine & Public Health | Nimodipine | aSAH | Subarachnoid hemorrhage | Intensive / Critical Care Medicine | Internal Medicine | Clinical trial | PROLONGED-RELEASE IMPLANTS | MANAGEMENT | VASOSPASM | DELAYED CEREBRAL-ISCHEMIA | CLINICAL NEUROLOGY | SCALE | CRITICAL CARE MEDICINE
Neurology | Cerebral aneurysm | Delayed cerebral ischemia | Extended release | Medicine & Public Health | Nimodipine | aSAH | Subarachnoid hemorrhage | Intensive / Critical Care Medicine | Internal Medicine | Clinical trial | PROLONGED-RELEASE IMPLANTS | MANAGEMENT | VASOSPASM | DELAYED CEREBRAL-ISCHEMIA | CLINICAL NEUROLOGY | SCALE | CRITICAL CARE MEDICINE
Journal Article
Neurosurgery, ISSN 0148-396X, 06/2019, Volume 84, Issue 6, pp. 1157 - 1168
Abstract BACKGROUND Minimally invasive surgery procedures, including stereotactic catheter aspiration and clearance of intracerebral hemorrhage (ICH) with...
Intracranial hemorrhage | MISTIE | Minimally invasive surgery | Recombinant tissue plasminogen activator | Intraparenchymal hemorrhage | SURGERY | MANAGEMENT | EFFICACY | GUIDELINES | GUIDANCE | HEMATOMAS | CLINICAL NEUROLOGY | STROKE | PLACEMENT | INITIAL CONSERVATIVE TREATMENT | CATHETERS | INTRAVENTRICULAR HEMORRHAGE
Intracranial hemorrhage | MISTIE | Minimally invasive surgery | Recombinant tissue plasminogen activator | Intraparenchymal hemorrhage | SURGERY | MANAGEMENT | EFFICACY | GUIDELINES | GUIDANCE | HEMATOMAS | CLINICAL NEUROLOGY | STROKE | PLACEMENT | INITIAL CONSERVATIVE TREATMENT | CATHETERS | INTRAVENTRICULAR HEMORRHAGE
Journal Article
WORLD NEUROSURGERY, ISSN 1878-8750, 08/2019, Volume 128, pp. E639 - E648
BACKGROUND: Clazosentan, an endothelin-1 receptor antagonist, has been shown to prevent the development of large vessel angiographic vasospasm after aneurysmal...
SURGERY | MANAGEMENT | Subarachnoid hemorrhage | Aneurysm | Cerebral vasospasm | TIME | NIMODIPINE | Endothelin-1 receptor antagonist | RECEPTOR ANTAGONIST | CLINICAL NEUROLOGY | TRIAL | DOUBLE-BLIND | ENDOTHELIN | Stroke (Disease) | Medicine, Experimental | Medical research | Endothelin | Analysis
SURGERY | MANAGEMENT | Subarachnoid hemorrhage | Aneurysm | Cerebral vasospasm | TIME | NIMODIPINE | Endothelin-1 receptor antagonist | RECEPTOR ANTAGONIST | CLINICAL NEUROLOGY | TRIAL | DOUBLE-BLIND | ENDOTHELIN | Stroke (Disease) | Medicine, Experimental | Medical research | Endothelin | Analysis
Journal Article
Journal of neurosurgery, ISSN 0022-3085, 12/2013, Volume 119, Issue 6, pp. 1611 - 1619
Aneurysmal subarachnoid hemorrhage (aSAH) predisposes to delayed neurological deficits, including stroke and cognitive and neuropsychological abnormalities....
Severity of Illness Index | Vasospasm, Intracranial - etiology | Anticoagulants - administration & dosage | Vasospasm, Intracranial - surgery | Humans | Middle Aged | Clinical Protocols | Heparin - administration & dosage | Male | Treatment Outcome | Administration, Cutaneous | Heparin - adverse effects | Anticoagulants - pharmacology | Adult | Female | Venous Thrombosis - prevention & control | Aged | Retrospective Studies | Infusions, Intravenous | Heparin - pharmacology | Subarachnoid Hemorrhage - drug therapy | Vasospasm, Intracranial - drug therapy | heparin | inflammation | cerebral vasospasm | subarachnoid hemorrhage | vascular disorders
Severity of Illness Index | Vasospasm, Intracranial - etiology | Anticoagulants - administration & dosage | Vasospasm, Intracranial - surgery | Humans | Middle Aged | Clinical Protocols | Heparin - administration & dosage | Male | Treatment Outcome | Administration, Cutaneous | Heparin - adverse effects | Anticoagulants - pharmacology | Adult | Female | Venous Thrombosis - prevention & control | Aged | Retrospective Studies | Infusions, Intravenous | Heparin - pharmacology | Subarachnoid Hemorrhage - drug therapy | Vasospasm, Intracranial - drug therapy | heparin | inflammation | cerebral vasospasm | subarachnoid hemorrhage | vascular disorders
Journal Article
Journal of neurosurgery, ISSN 0022-3085, 01/2013, Volume 118, Issue 1, pp. 74 - 83
The object of this study was to assess outcomes in patients with arteriovenous malformations (AVMs) treated by Gamma Knife stereotactic radiosurgery (SRS);...
Follow-Up Studies | Humans | Adult | Brain - surgery | Female | Male | Treatment Outcome | Intracranial Arteriovenous Malformations - surgery | Radiosurgery - instrumentation | Retrospective Studies
Follow-Up Studies | Humans | Adult | Brain - surgery | Female | Male | Treatment Outcome | Intracranial Arteriovenous Malformations - surgery | Radiosurgery - instrumentation | Retrospective Studies
Journal Article