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Molecular neurobiology, ISSN 0893-7648, 04/2019, pp. 1 - 17
Multidrug resistance protein 1 (MDR1, ABCB1, P-glycoprotein) is a critical efflux transporter that extrudes chemicals from the blood-brain barrier (BBB) and... 
Cytochrome | Histone deacetylase | Brain | Rhodamine | Cytochrome P450 | Multidrug resistance | Hydroxamic acid | Hydrocarbons | Regulatory sequences | Valproic acid | Endothelial cells | Proteins | MDR1 protein | Inhibitors | Blood-brain barrier | Acids | Acetylation | Xenobiotics | P-Glycoprotein | Naphthoflavone | Deoxyribonucleic acid--DNA
Journal Article
Toxicology, ISSN 0300-483X, 03/2019, Volume 416, p. 15
Hepatic carboxylesterases (Ces) catalyze the metabolism of drugs, environmental toxicants, and endogenous lipids and are known to be regulated by multiple... 
RNA | Liver | Physiological aspects | Progesterone | Ammonium perfluorooctanoate | Protein binding
Journal Article
Toxicological Sciences, ISSN 1096-6080, 04/2019, Volume 168, Issue 2, pp. 394 - 404
Abstract In the placenta, the breast cancer resistance protein (BCRP)/ABCG2 efflux transporter limits the maternal-to-fetal transfer of drugs and chemicals.... 
BCRP | zearalenone | MOUSE | MODEL | GLYBURIDE | mycotoxin | NANOPARTICLES | METABOLISM | SUBSTRATE | placenta | TOXICOLOGY | SECRETION | EXPRESSION | CELL-LINE | ABCG2 | CANCER RESISTANCE PROTEIN
Journal Article
Current drug metabolism, 2015, Volume 16, Issue 2, p. 124
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, pp. 619 - 627
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 07/2012, Volume 40, Issue 7, pp. 1366 - 1379
The transcription factors aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR), pregnane X receptor (PXR), peroxisome proliferator-activated... 
TRANSCRIPTION FACTORS | PRIMARY HUMAN HEPATOCYTES | ANTIOXIDANT RESPONSE ELEMENT | MESSENGER-RNA EXPRESSION | CONSTITUTIVE ANDROSTANE RECEPTOR | BILIARY-EXCRETION | PROLIFERATOR-ACTIVATED RECEPTOR | MOUSE-LIVER | PHARMACOLOGY & PHARMACY | MICROSOMAL-ENZYME INDUCERS | PREGNANE-X-RECEPTOR | Inactivation, Metabolic | Receptors, Steroid - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | NAD(P)H Dehydrogenase (Quinone) - genetics | Organic Anion Transporters - metabolism | Glucuronosyltransferase - genetics | Organic Anion Transporters - genetics | Glutathione Transferase - genetics | Receptors, Aryl Hydrocarbon - metabolism | Female | NF-E2-Related Factor 2 - genetics | Sulfotransferases - metabolism | Aldehyde Dehydrogenase - metabolism | Sulfotransferases - genetics | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Receptors, Aryl Hydrocarbon - genetics | Glutathione Transferase - metabolism | Aldehyde Dehydrogenase - genetics | PPAR alpha - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | Mice, Knockout | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Animals | Glucuronosyltransferase - metabolism | Receptors, Steroid - genetics | NF-E2-Related Factor 2 - metabolism | Cytochrome P-450 Enzyme System - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | PPAR alpha - metabolism | Multidrug Resistance-Associated Proteins | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article
Journal of biochemical and molecular toxicology, ISSN 1095-6670, 03/2019, pp. e22318 - e22318
Multidrug resistance protein 1 (MDR1) and breast cancer resistance protein (BCRP) protect the brain by restricting the passage of chemicals across the... 
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 02/2013, Volume 41, Issue 2, pp. 326 - 331
Journal Article
Journal of Maternal-Fetal and Neonatal Medicine, ISSN 1476-7058, 2018, pp. 1 - 6
Fibroblast growth factor 19 (FGF19) is a gut-derived hormone that regulates the expression of CYP7A1, the rate-limiting enzyme in bile acid (BA) synthesis... 
liver disease | Cholestasis | cholesterol 7α-hydroxylase | fibroblast growth factor 19
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 01/2018, Volume 33, Issue 1, pp. S10 - S10
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 05/2017, Volume 31, Issue 5, p. e21880
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 12/2015, Volume 29, Issue 12, pp. 545 - 551
Journal Article
Current Drug Metabolism, ISSN 1389-2002, 07/2015, Volume 16, Issue 2, pp. 124 - 140
This review will provide a comprehensive overview of the interactions between dietary isoflavones and the ATP-binding cassette (ABC) G2 efflux transporter,... 
BCRP | Biochanin A | Daidzein | Genistein | Isoflavones | Phase II metabolites | isoflavones | BIOCHEMISTRY & MOLECULAR BIOLOGY | COLON-CARCINOMA-CELLS | P-GLYCOPROTEIN | daidzein | IN-VITRO | MILK SECRETION | genistein | PROTEIN BCRP/ABCG2 | biochanin A | SOY ISOFLAVONES | PHARMACOLOGY & PHARMACY | phase II metabolites | HUMAN LIVER | ABC HALF-TRANSPORTER | BREAST-CANCER RESISTANCE | IMATINIB MESYLATE
Journal Article
Journal of Biochemical and Molecular Toxicology, ISSN 1095-6670, 06/2015, Volume 29, Issue 6, pp. 261 - 266
Journal Article
Journal Article
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