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index medicus (9) 9
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autophagy (4) 4
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1. Full Text Guidelines for the use and interpretation of assays for monitoring autophagy
by Klionsky, Daniel J and Abdalla, Fabio C and Abeliovich, Hagai and Abraham, Robert T and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agholme, Lotta and Agnello, Maria and Agostinis, Patrizia and Aguirre-Ghiso, Julio A and Ahn, Hyung Jun and Ait-Mohamed, Ouardia and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akira, Shizuo and Al-Younes, Hesham M and Al-Zeer, Munir A and Albert, Matthew L and Albin, Roger L and Alegre-Abarrategui, Javier and Aleo, Maria Francesca and Alirezaei, Mehrdad and Almasan, Alexandru and Almonte-Becerril, Maylin and Amano, Atsuo and Amaravadi, Ravi K and Amarnath, Shoba and Amer, Amal O and Andrieu-Abadie, Nathalie and Anantharam, Vellareddy and Ann, David K and Anoopkumar-Dukie, Shailendra and Aoki, Hiroshi and Apostolova, Nadezda and Arancia, Giuseppe and Aris, John P and Asanuma, Katsuhiko and Asare, Nana Y.O and Ashida, Hisashi and Askanas, Valerie and Askew, David S and Auberger, Patrick and Baba, Misuzu and Backues, Steven K and Baehrecke, Eric H and Bahr, Ben A and Bai, Xue-Yuan and Bailly, Yannick and Baiocchi, Robert and Baldini, Giulia and Balduini, Walter and Ballabio, Andrea and Bamber, Bruce A and Bampton, Edward T.W and Juhász, Gábor and Bartholomew, Clinton R and Bassham, Diane C and Bast, Robert C and Batoko, Henri and Bay, Boon-Huat and Beau, Isabelle and Béchet, Daniel M and Begley, Thomas J and Behl, Christian and Behrends, Christian and Bekri, Soumeya and Bellaire, Bryan and Bendall, Linda J and Benetti, Luca and Berliocchi, Laura and Bernardi, Henri and Bernassola, Francesca and Besteiro, Sébastien and Bhatia-Kissova, Ingrid and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Boise, Lawrence H and Bonaldo, Paolo and Boone, David L and Bornhauser, Beat C and Bortoluci, Karina R and Bossis, Ioannis and Bost, Frédéric and Bourquin, Jean-Pierre and Boya, Patricia and Boyer-Guittaut, Michaël and Bozhkov, Peter V and Brady, Nathan R and Brancolini, Claudio and Brech, Andreas and Brenman, Jay E and Brennand, Ana and Bresnick, Emery H and Brest, Patrick and Bridges, Dave and Bristol, Molly L and Brookes, Paul S and Brown, Eric J and Brumell, John H and ... and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Geriatrik and Institutionen för medicin och hälsa and Farmakologi and Experimentell patologi and Hälsouniversitetet and Cellbiologi
Autophagy, ISSN 1554-8627, 04/2012, Volume 8, Issue 4, pp. 445 - 544
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and... 
stress | vacuole | autolysosome | flux | LC3 | autophagosome | lysosome | phagophore | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Phagophore | Lysosome | Autolysosome | Flux | Autophagosome | Vacuole | Stress | ACTIVATED PROTEIN-KINASE | CHAPERONE-MEDIATED AUTOPHAGY | VACUOLE TARGETING PATHWAY | ENDOPLASMIC-RETICULUM STRESS | ISOLATED RAT HEPATOCYTES | STARVATION-INDUCED AUTOPHAGY | GLUCAGON-INDUCED AUTOPHAGY | CELL BIOLOGY | PROGRAMMED CELL-DEATH | BREAST-CANCER CELLS | BETAINE HOMOCYSTEINE METHYLTRANSFERASE | Biological Assay - methods | Animals | Autophagy - genetics | Models, Biological | Humans | Life Sciences | Cellular Biology | Review | Medical and Health Sciences | Medicin och hälsovetenskap
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2. Full Text Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
by Vaccaro, Olga and Masulli, Maria and Nicolucci, Antonio and Bonora, Enzo and Del Prato, Stefano and Maggioni, Aldo Pietro and Maggioni, Aldo P and Rivellese, Angela A and Rivellese, Angela Albarosa and Squatrito, Sebastiano and Giorda, Carlo B and Sesti, Giorgio and Mocarelli, Paolo and Lucisano, Giuseppe and Sacco, Michele and Signorini, Stefano and Cappellini, Fabrizio and Perriello, Gabriele and Babini, Massimiliano and Babini, Anna Carla and Lapolla, Annunziata and Gregori, Giovanna and Giordano, Carla and Corsi, Simona and Corsi, Laura and Corsi, Anna and Buzzetti, Raffaella and Clemente, Gennaro and Di Cianni, Graziano and Iannarelli, Rossella and Cordera, Renzo and La Macchia, Olga and Zamboni, Chiara and Scaranna, Cristiana and Boemi, Massimo and Iovine, Ciro and Lauro, Davide and Leotta, Sergio and Dall'Aglio, Elisabetta and Cannarsa, Emanuela and Tonutti, Laura and Pugliese, Giuseppe and Bossi, Antonio C and Bossi, Antonio Carlo and Anichini, Roberto and Dotta, Francesco and Di Benedetto, Antonino and Citro, Giuseppe and Antenucci, Daniela and Ricci, Lucia and Giorgino, Francesco and Santini, Costanza and Gnasso, Agostino and De Cosmo, Salvatore and Zavaroni, Donatella and Vedovato, Monica and Consoli, Agostino and Calabrese, Maria and di Bartolo, Paolo and Fornengo, Paolo and Riccardi, Gabriele and D'Angelo, Federica and D'Angelo, Paola and Giansanti, Roberto and Tanase, Laura and Lanari, Luigi and Testa, Ivano and Pancani, Francesca and Ranchelli, Anna and Vagheggi, Paolo and Scatona, Alessia and Fontana, Lucia and Laviola, Luigi and Tarantino, Lucia and Ippolito, Claudia and Ippolito, Giulio and Gigantelli, Vittoria and Manicone, Mariangela and Conte, Eleonora and Trevisan, Roberto and Rota, Giuseppe and Rota, Rossella and Dodesini, Alessandro R and Reggiani, Giulio Marchesini and Montesi, Luca and Mazzella, Natalia and Forlani, Gabriele and Caselli, Chiara and Di Luzio, Raffaella and Mazzotti, Arianna and Aiello, Antimo and Barrea, Angelina and Musto, Antonio and D'Amico, Fiorentina and Sinagra, Tiziana and Longhitano, Sara and Trowpea, Vanessa and Sparti, Maria and Italia, Salvatore and Lisi, Enrico and ... and Thizolidinediones Sulfonylureas Ca and Italian Diabetes Society and Thiazolidinediones Or Sulfonylureas Cardiovascular Accidents Intervention Trial (TOSCA.IT) study group
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 11/2017, Volume 5, Issue 11, pp. 887 - 897
The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We... 
MORTALITY | INSULIN | GLYCEMIC CONTROL | IMPACT | METAANALYSIS | GLUCOSE-LOWERING DRUGS | ENDOCRINOLOGY & METABOLISM | FOLLOW-UP | RISK | GLIMEPIRIDE | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Metformin - therapeutic use | Cardiovascular Diseases - drug therapy | Humans | Middle Aged | Pioglitazone | Sulfonylurea Compounds - therapeutic use | Male | Treatment Outcome | Diabetes Mellitus, Type 2 - epidemiology | Incidence | Thiazolidinediones - therapeutic use | Cardiovascular Diseases - epidemiology | Female | Aged | Drug Therapy, Combination | Diabetes Mellitus, Type 2 - complications
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3. Full Text Guidelines for the use and interpretation of assays for monitoring autophagy
by Klionsky, Daniel J and Abeliovich, Hagai and Abraham, Robert T and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agholme, Lotta and Agnello, Maria and Agostinis, Patrizia and Aguirre-Ghiso, Julio A and Ahn, Hyung Jun and Ait-Mohamed, Ouardia and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akira, Shizuo and Al-Younes, Hesham M and Al-Zeer, Munir A and Albert, Matthew L and Albin, Roger L and Alegre-Abarrategui, Javier and Aleo, Maria Francesca and Alirezaei, Mehrdad and Almasan, Alexandru and Almonte-Becerril, Maylin and Amano, Atsuo and Amaravadi, Ravi and Amarnath, Shoba and Amer, Amal O and Andrieu-Abadie, Nathalie and Anantharam, Vellareddy and Bozhkov, Peter and Zuckerbraun, Brian and Sveriges lantbruksuniversitet
Autophagy, ISSN 1554-8635, 2012, Volume 3, Issue 4, p. 445
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and... 
Cellbiologi | Cell Biology
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4. Full Text ER signaling regulation drives the switch between autophagy and apoptosis in NRK-52E cells exposed to cisplatin
by Rovetta, Francesca and Stacchiotti, Alessandra and Consiglio, Antonella and Cadei, Moris and Grigolato, Pier Giovanni and Lavazza, Antonio and Rezzani, Rita and Aleo, Maria Francesca
Experimental Cell Research, ISSN 0014-4827, 2012, Volume 318, Issue 3, pp. 238 - 250
Cisplatin (cisPt) use in chemotherapy is limited by the occurrence of a severe nephrotoxicity. Both autophagy and apoptosis seem to contribute in kidney... 
ER chaperones | ER stress pathway | Nephrotoxicity | Autophagy | Cisplatin | Apoptosis | UNFOLDED-PROTEIN RESPONSE | INJURY | DEATH | MECHANISMS | ENDOPLASMIC-RETICULUM STRESS | MAMMALIAN-CELLS | CELL BIOLOGY | ONCOLOGY | TUBULAR EPITHELIAL-CELLS | INDUCED NEPHROTOXICITY | KIDNEY | LIFE | Apoptosis - drug effects | Cell Survival - genetics | Endoplasmic Reticulum - metabolism | Apoptosis - genetics | Autophagy - physiology | Cytoprotection - physiology | Endoplasmic Reticulum Stress - genetics | Autophagy - drug effects | Heat-Shock Proteins - genetics | Kidney - metabolism | Endoplasmic Reticulum - drug effects | Cytoprotection - drug effects | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Autophagy - genetics | Cell Line | Cell Survival - drug effects | Kidney - drug effects | Endoplasmic Reticulum Stress - drug effects | Membrane Proteins - genetics | Heat-Shock Proteins - metabolism | Endoplasmic Reticulum - physiology | Rats | HSP70 Heat-Shock Proteins - genetics | Kidney - cytology | Signal Transduction - genetics | Cisplatin - pharmacology | Kidney - ultrastructure | HSP70 Heat-Shock Proteins - metabolism | Gene Expression Regulation - drug effects | Animals | Signal Transduction - drug effects | Cytoprotection - genetics | Apoptosis - physiology | Endoplasmic Reticulum Stress - physiology | Enzymes | Taurine | Automobile driving | Dimethyl sulfoxide | Motor vehicle driving | Signal transduction | Chemotherapy | Cells | Index Medicus
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5. Full Text Cisplatin triggers atrophy of skeletal C2C12 myotubes via impairment of Akt signalling pathway and subsequent increment activity of proteasome and autophagy systems
by Fanzani, Alessandro and Zanola, Alessandra and Rovetta, Francesca and Rossi, Stefania and Aleo, Maria Francesca
Toxicology and Applied Pharmacology, ISSN 0041-008X, 02/2011, Volume 250, Issue 3, pp. 312 - 321
Cisplatin (cisPt) is an antineoplastic drug which causes an array of adverse effects on different organs and tissues, including skeletal muscle. In this work... 
Atrophy | Akt | Autophagy | Cisplatin | Myoblasts | Proteasome | CANCER CACHEXIA | OXIDATIVE STRESS | MUSCLE ATROPHY | CELL-DEATH | HYPERTROPHY | IN-VITRO | DISEASE STATES | PROTEIN-DEGRADATION | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MOLECULAR-MECHANISMS | Cell Survival - drug effects | Phosphorylation | Signal Transduction | Apoptosis - drug effects | Cells, Cultured | Proto-Oncogene Proteins c-akt - physiology | Antineoplastic Agents - administration & dosage | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Autophagy - drug effects | Antineoplastic Agents - toxicity | Cisplatin - administration & dosage | Necrosis | Dose-Response Relationship, Drug | Myoblasts - drug effects | Myoblasts - metabolism | Animals | Cisplatin - toxicity | Muscle Fibers, Skeletal - pathology | Transcription, Genetic | Mice | Proteasome Endopeptidase Complex - metabolism | Phosphates | Albumin | GABA | Superoxide | Protein kinases | ANIMALS | DOMESTIC ANIMALS | ATROPHY | DMSO | ORGANIC COMPOUNDS | CATTLE | ALBUMINS | MYOBLASTS | ANTINEOPLASTIC DRUGS | 60 APPLIED LIFE SCIENCES | SKELETON | ORGANS | RUMINANTS | SULFOXIDES | DRUGS | ORGANIC SULFUR COMPOUNDS | VERTEBRATES | PROTEINS | BODY | PATHOLOGICAL CHANGES | MUSCLES | MAMMALS
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6. Full Text Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead
by Stacchiotti, Alessandra and Morandini, Fausta and Bettoni, Francesca and Schena, Ilaria and Lavazza, Antonio and Grigolato, Pier Giovanni and Apostoli, Pietro and Rezzani, Rita and Aleo, Maria Francesca
Toxicology, ISSN 0300-483X, 2009, Volume 264, Issue 3, pp. 215 - 224
Abstract A close link between stress protein up-regulation and oxidative damage may provide a novel therapeutic tool to counteract nephrotoxicity induced by... 
Emergency | Pb(II) | Oxidative stress | Hg(II) | NRK-52E | Stress proteins | Nephrotoxicity | RAT-KIDNEY | MOLECULAR CHAPERONES | TOXICITY | FREE-RADICALS | HEAT-SHOCK PROTEINS | EPITHELIAL-CELLS | GLUTATHIONE | TUBULAR INJURY | ER CHAPERONE BIP | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CHLORIDE | Metallothionein - metabolism | Molecular Chaperones - metabolism | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Glutathione - metabolism | Endoplasmic Reticulum - metabolism | Necrosis | Dose-Response Relationship, Drug | Time Factors | Endoplasmic Reticulum - drug effects | Lead - toxicity | Biomarkers - metabolism | Cell Line | Cell Survival - drug effects | Kidney Tubules, Proximal - pathology | Heat-Shock Proteins - metabolism | Glutathione Transferase - metabolism | Rats | HSP72 Heat-Shock Proteins - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Animals | Kidney Tubules, Proximal - metabolism | HSP27 Heat-Shock Proteins - metabolism | Mercuric Chloride - toxicity | Cell Proliferation - drug effects | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Kidney Tubules, Proximal - drug effects | Proteins | Heat shock proteins | Medical colleges | Human anatomy | Glutathione transferase | Glutathione | Index Medicus
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7. Full Text Cobalt triggers necrotic cell death and atrophy in skeletal C2C12 myotubes
by Rovetta, Francesca and Stacchiotti, Alessandra and Faggi, Fiorella and Catalani, Simona and Apostoli, Pietro and Fanzani, Alessandro and Aleo, Maria Francesca
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2013, Volume 271, Issue 2, pp. 196 - 205
Severe poisoning has recently been diagnosed in humans having hip implants composed of cobalt–chrome alloys due to the release of particulate wear debris on... 
Atrophy | Cell stress | C2C12 myotubes | Necroptosis | Cobalt | Skeletal muscle | APOPTOSIS | MUSCLE ATROPHY | MECHANISMS | HYPOXIA | GRP94 | HIP | HEAT-SHOCK PROTEINS | GENOTOXICITY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | UP-REGULATION | Immunohistochemistry | Cell Line | Prostheses and Implants - adverse effects | Coloring Agents | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Fluorometry | Muscle Fibers, Skeletal - drug effects | Autophagy | Blotting, Western | Necrosis | Tetrazolium Salts | Cobalt - toxicity | Myoblasts - drug effects | Proteasome Endopeptidase Complex - drug effects | Signal Transduction - drug effects | Muscle Fibers, Skeletal - pathology | Thiazoles | Indicators and Reagents | Cell Death - drug effects | Oncogene Protein v-akt - metabolism | Real-Time Polymerase Chain Reaction | Muscles | Heat shock proteins | Biochemistry | Cell death | Analysis | Index Medicus | HOMEOSTASIS | POLYETHYLENES | ATROPHY | PHOSPHORYLATION | 60 APPLIED LIFE SCIENCES | COBALT CHLORIDES | NECROSIS | ALLOYS | IN VITRO | MICE | POISONING | RECEPTORS | MUSCLES | CERAMICS | COBALT
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