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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2004, Volume 101, Issue 15, pp. 5598 - 5603
Viral infection of mammalian host results in the activation of innate immune responses. Toll-like receptors (TLRs) have been shown to mediate the recognition... 
Biological Sciences | Double stranded RNA | RNA | Dendritic cells | B lymphocytes | Antivirals | Bone marrow | Viruses | Cultured cells | Infections | Bone marrow cells | PLASMACYTOID DENDRITIC CELLS | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | FUSION PROTEIN | GLYCOPROTEINS | INTERFERON-PRODUCING CELLS | INFECTION | TLR7 | VESICULAR STOMATITIS-VIRUS | IDENTIFICATION | EXPRESSION | Endosomes - immunology | Dendritic Cells - immunology | Toll-Like Receptor 7 | Orthomyxoviridae - immunology | Chloroquine - pharmacology | RNA, Viral - genetics | Bone Marrow Cells - immunology | Peritoneum - cytology | Antigens, Differentiation - metabolism | Membrane Glycoproteins - immunology | Macrophages - immunology | Endosomes - virology | Vesicular stomatitis Indiana virus - genetics | Spleen - cytology | Myeloid Differentiation Factor 88 | Chick Embryo | Receptors, Cell Surface - immunology | Membrane Glycoproteins - genetics | Mice, Knockout | Adaptor Proteins, Signal Transducing | Animals | Interferon-alpha - secretion | Receptors, Cell Surface - deficiency | Rhabdoviridae Infections - immunology | Orthomyxoviridae - genetics | RNA, Viral - immunology | Mice | Cytokines - biosynthesis | Membrane Glycoproteins - deficiency | Receptors, Immunologic - metabolism | Vesicular stomatitis Indiana virus - immunology | Receptors, Cell Surface - genetics | RNA viruses | Research
Journal Article
Journal Article
Journal Article
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2014, Volume 1197, pp. 209 - 225
Innate immune recognition of microbial components is critical for the onset of an appropriate immune response against invading pathogens, in particular by... 
Dendritic cell | Bacteria | TLR | Animals | Bone Marrow Cells - cytology | Signal Transduction - physiology | Mice | Toll-Like Receptors - metabolism | Dendritic Cells - metabolism | Microscopy, Fluorescence | Bacterial Infections - metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2004, Volume 101, Issue 10, pp. 3516 - 3521
Several subsets of dendritic cells have been shown to produce type I IFN in response to viral infections, thereby assisting the natural killer cell-dependent... 
Biological Sciences | Phenotypes | Receptors | Double stranded RNA | Cytokines | Natural killer T cells | Alleles | Infections | Mice | Viral infections | Genotypes | PLASMACYTOID DENDRITIC CELLS | INTERFERON-ALPHA/BETA | NATURAL-KILLER-CELLS | DOUBLE-STRANDED-RNA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MURINE CYTOMEGALOVIRUS | NF-KAPPA-B | BACTERIAL CPG-DNA | VIRAL-INFECTION | ACTIVATION RECEPTOR | Toll-Like Receptor 3 | Membrane Glycoproteins - metabolism | DNA, Complementary - genetics | Immunity, Innate - genetics | Molecular Sequence Data | Toll-Like Receptor 9 | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - genetics | Mutation, Missense | DNA-Binding Proteins - metabolism | Toll-Like Receptors | Mice, Mutant Strains | Oligodeoxyribonucleotides - genetics | Killer Cells, Natural - immunology | Antigens, Differentiation - metabolism | Amino Acid Sequence | Immunity, Innate - drug effects | Signal Transduction | Mice, Inbred C57BL | Receptors, Immunologic - deficiency | Receptors, Cell Surface - metabolism | Myeloid Differentiation Factor 88 | DNA-Binding Proteins - genetics | Membrane Glycoproteins - genetics | Mice, Knockout | Sequence Homology, Amino Acid | Point Mutation | Adaptor Proteins, Signal Transducing | Phenotype | Animals | Receptors, Cell Surface - deficiency | Antigens, Differentiation - genetics | Mice, Inbred BALB C | Oligodeoxyribonucleotides - pharmacology | Receptors, Immunologic - genetics | Cytokines - biosynthesis | Membrane Glycoproteins - deficiency | Receptors, Immunologic - metabolism | Receptors, Cell Surface - genetics | Dendritic cells | Research
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 6, pp. 2372 - 2377
The critical role of Toll-like receptors (TLRs) in mammalian host defense has been extensively explored in recent years. The capacity of about 10 TLRs to... 
Double stranded RNA | Vascular diseases | Atherosclerosis | Toll like receptors | Ligands | Agonists | Mice | Inflammation | Lesions | Carotid arteries | Innate immunity | Intimal hyperplasia | DOUBLE-STRANDED-RNA | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | intimal hyperplasia | INTERFERON-BETA | KAPPA-B | APOLIPOPROTEIN-E | innate immunity | MULTIPLE-SCLEROSIS | inflammation | SMOOTH-MUSCLE-CELLS | E-DEFICIENT MICE | Carotid Arteries - metabolism | Poly I-C - pharmacology | Muscle, Smooth, Vascular - metabolism | Signal Transduction | Humans | Myocytes, Smooth Muscle - pathology | Male | Toll-Like Receptor 3 - agonists | Toll-Like Receptor 3 - metabolism | Mice, Knockout | Muscle, Smooth, Vascular - pathology | Animals | Hypercholesterolemia - pathology | Carotid Artery Diseases - pathology | Female | Carotid Arteries - pathology | Toll-Like Receptor 3 - genetics | Carotid Artery Diseases - metabolism | Hypercholesterolemia - metabolism | Myocytes, Smooth Muscle - metabolism | Interferon Inducers - pharmacology | Physiological aspects | Immunity | Health aspects | Arteries | Toll-Like Receptor 3 | Carotid Arteries | Life Sciences | Muscle, Smooth, Vascular | Myocytes, Smooth Muscle | Hypercholesterolemia | Immunology | Carotid Artery Diseases | Interferon Inducers | Poly I-C | Biological Sciences
Journal Article
Nature Immunology, ISSN 1529-2908, 12/2003, Volume 4, Issue 12, pp. 1223 - 1229
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2006, Volume 103, Issue 33, pp. 12487 - 12492
Journal Article