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1. Full Text Commentary: The static use of the transannular patch in the repair of tetralogy of Fallot
by Alfieris, George M and Swartz, Michael F and Algahim, Mohamed
The Journal of Thoracic and Cardiovascular Surgery, ISSN 0022-5223, 09/2019
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2. Full Text The Initial Glimpse at Long-term Outcomes Following the Repair of Truncus Arteriosus
by Alfieris, George M and Swartz, Michael F
Seminars in Thoracic and Cardiovascular Surgery, ISSN 1043-0679, 2016, Volume 28, Issue 2, pp. 512 - 513
The article by Naimo and colleagues (outcomes of truncus arteriosus repair in children: 35 years of experience from a single center) provides the initial... 
Right ventricular outflow tract reconstruction | Congenital heart disease | Interrupted aortic arch | Truncus arteriosus | Reoperation | Truncus Arteriosus, Persistent | Humans | Truncus Arteriosus - surgery
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3. Full Text Editorial Commentary: The Initial Glimpse at Long-Term Outcomes following the Repair of Truncus Arteriosus
by Alfieris, George M, MD and Swartz, Michael F, PhD
Seminars in Thoracic and Cardiovascular Surgery, ISSN 1043-0679, 2016
The article by Naimo and colleagues (Outcomes of truncus arteriosus repair in children: 35 years of experience from a single center) provides the initial... 
Cardiothoracic Surgery
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4. Full Text Successful surgical palliation of a triple-outlet right ventricle: A rare congenital cardiac malformation
by Traa, Beatrix S and Alfieris, George M and Wittlieb-Weber, Carol A
Cardiology in the Young, ISSN 1047-9511, 02/2015, Volume 26, Issue 2, pp. 403 - 405
Most commonly, hearts have either a single arterial trunk or two arterial trunks; however, rare reports exist of a tritruncal heart, a heart with three outflow... 
congenital heart disease | conotruncal malformation | Paediatrics | CARDIAC & CARDIOVASCULAR SYSTEMS | OUTFLOW TRACT | PEDIATRICS | TRITRUNCAL HEART | Heart Ventricles - abnormalities | Echocardiography | Follow-Up Studies | Heart Defects, Congenital - diagnostic imaging | Heart Defects, Congenital - surgery | Humans | Heart Ventricles - surgery | Male | Cardiac Surgical Procedures - methods | Heart Ventricles - diagnostic imaging | Infant, Newborn | Palliative Care - methods | Cardiology | Pulmonary arteries | Rodents | Coronary vessels | Veins & arteries
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5. Full Text Abstract 14749: Tetralogy of Fallot Repair During Infancy is Associated With Improved Outcomes Following Subsequent Pulmonary Valve Replacement
by Miller, Erica O and Swartz, Michael F and Simon, Bartholomew V and McGreevy, Megan B and Alfieris, George M
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A14749 - A14749
BackgroundRepair of tetralogy of Fallot (TOF) during infancy limits the duration of time that the right ventricular volume and pressure are elevated. Whether... 
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6. Full Text Use of a Dacron Annular Sparing Versus Limited Transannular Patch With Nominal Pulmonary Annular Expansion in Infants With Tetralogy of Fallot
by Simon, Bartholomew V., MD and Swartz, Michael F., PhD and Egan, Matthew, MD and Cholette, Jill M., MD and Gensini, Francisco, MD and Alfieris, George M., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2016, Volume 103, Issue 1, pp. 186 - 192
Background Repair of tetralogy of Fallot (ToF) using a transannular patch can result in severe pulmonary insufficiency (PI) and subsequent right ventricular... 
Surgery | Cardiothoracic Surgery | VENTRICULAR OUTFLOW TRACT | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | RESPIRATORY SYSTEM | RECONSTRUCTION | FOLLOW-UP | OUTCOMES | DILATATION | TRANSATRIAL-TRANSPULMONARY REPAIR | Echocardiography | Humans | Infant | Male | Treatment Outcome | Pulmonary Valve - surgery | Polyethylene Terephthalates | Suture Techniques - instrumentation | Tetralogy of Fallot - surgery | Tetralogy of Fallot - diagnosis | Sutures | Female | Cardiac Surgical Procedures - methods | Tetralogy of Fallot | Polyethylene terephthalate | Infants
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7. Full Text Outcomes Using a Conservative Versus Liberal Red Blood Cell Transfusion Strategy in Infants Requiring Cardiac Operation
by Cholette, Jill M., MD and Swartz, Michael F., PhD and Rubenstein, Jeffrey, MD and Henrichs, Kelly F., MT(ASCP) and Wang, Hongyue, PhD and Powers, Karen S., MD and Daugherty, L. Eugene, MD and Alfieris, George M., MD and Gensini, Francisco, MD and Blumberg, Neil, MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2016, Volume 103, Issue 1, pp. 206 - 214
Background The optimal hemoglobin for infants after cardiac operation is unknown. Red blood cells (RBCs) are commonly transfused to maintain high hemoglobin... 
Surgery | Cardiothoracic Surgery | MORTALITY | SURGERY | OXYGEN-CONSUMPTION | CARDIAC & CARDIOVASCULAR SYSTEMS | PREDICTOR | EFFICACY | CRITICALLY-ILL | RANDOMIZED CONTROLLED-TRIAL | MORBIDITY | RESPIRATORY SYSTEM | SURGERY PATIENTS | COMPLICATIONS | LACTATE LEVELS | Follow-Up Studies | Heart Defects, Congenital - surgery | Humans | Postoperative Complications - blood | Postoperative Complications - prevention & control | Infant | Male | Erythrocyte Transfusion - methods | Cardiac Surgical Procedures | Female | Retrospective Studies | Hemoglobins - analysis | Infant, Newborn | Heart Defects, Congenital - blood | Practice Guidelines as Topic | Glycosylated hemoglobin | Lactates | Infants
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8. Full Text Neurodevelopmental Delay After the Neonatal Repair of Coarctation and Arch Obstruction
by Simon, Bartholomew V and Swartz, Michael F and Orie, Jennifer M and Adams, Heather R and Seltzer, Laurie E and Angona, Ron E and Atallah-Yunes, Nader H and Alfieris, George M
The Annals of Thoracic Surgery, ISSN 0003-4975, 11/2019, Volume 108, Issue 5, pp. 1416 - 1422
Although single ventricle physiology and cyanosis are known risk factors for neurodevelopmental delay (NDD), the impacts of isolated coarctation (Iso CoA)... 
SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | GREAT-ARTERIES | ARTERIAL SWITCH OPERATION | AORTIC-ARCH | DEXTRO-TRANSPOSITION | CHILDREN | RESPIRATORY SYSTEM | ADOLESCENTS | CONGENITAL HEART-DISEASE | INFANTS | OUTCOMES | CEREBRAL-BLOOD-FLOW | Infants (Newborn) | Heart | Genetic disorders | Coronary artery bypass | Pediatric cardiology | Congenital heart disease | Heart diseases
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9. Full Text Long-Term Survival and Freedom From Reoperation After Placement of a Pulmonary Xenograft Valved Conduit
by Alfieris, George M., MD and Swartz, Michael F., PhD and Lehoux, Juan, MD and Bove, Edward L., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2016, Volume 102, Issue 2, pp. 602 - 607
Background The optimal choice for pulmonary valve replacement (PVR) remains controversial. This study hypothesized that xenografts used for PVR would result in... 
Surgery | Cardiothoracic Surgery | SURGERY | HOMOGRAFT | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | INSUFFICIENCY | FALLOT | OUTFLOW TRACT RECONSTRUCTION | REPLACEMENT | RIGHT VENTRICLE | TETRALOGY | REPAIR | RESPIRATORY SYSTEM | ALLOGRAFTS | Reoperation | United States - epidemiology | Echocardiography | Survival Rate - trends | Follow-Up Studies | Pulmonary Valve - diagnostic imaging | Heart Valve Prosthesis | Humans | Bioprosthesis | Male | Postoperative Complications - mortality | Prosthesis Design | Pulmonary Valve - surgery | Cardiac Catheterization | Heterografts | Pulmonary Valve Insufficiency - diagnosis | Adolescent | Female | Time and Motion Studies | Pulmonary Valve Insufficiency - surgery | Retrospective Studies | Pulmonary Valve Insufficiency - mortality | Child | Valves | Personal video recorders
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10. Full Text Neurodevelopmental outcomes after neonatal cardiac surgery: Role of cortical isoelectric activity
by Seltzer, Laurie, DO and Swartz, Michael F., PhD and Kwon, Jennifer, MD and Burchfiel, James, PhD and Cholette, Jill M., MD and Wang, Hongyue, PhD and Sweeney, Dawn, MD and Adams, Heather R., MD and Meagher, Cecilia, MD and Angona, Ron, CCP and Guillet, Ronnie, MD, PhD and Alfieris, George M., MD
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2015, Volume 151, Issue 4, pp. 1137 - 1144
Abstract Objectives Neonates with congenital heart disease are at risk for impaired neurodevelopment after cardiac surgery. We hypothesized that intraoperative... 
Cardiothoracic Surgery | neurodevelopmental outcomes | deep hypothermic circulatory arrest | EEG | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | RECONSTRUCTION | CHILDREN | TRIAL | RESPIRATORY SYSTEM | CONGENITAL HEART-DISEASE | HYPOTHERMIC CIRCULATORY ARREST | INFANTS | PERFUSION | SINGLE VENTRICLE | AGE | Postoperative Complications - physiopathology | Prospective Studies | Age Factors | Heart Defects, Congenital - surgery | Humans | Child, Preschool | Infant Behavior | Male | Treatment Outcome | Cardiac Surgical Procedures - adverse effects | Electroencephalography | Time Factors | Cerebral Cortex - growth & development | Female | Heart Defects, Congenital - diagnosis | Child Development | Heart Defects, Congenital - physiopathology | Intraoperative Neurophysiological Monitoring - methods | Child | Infant, Newborn | Infants (Newborn) | Disease susceptibility | Congenital heart disease | Genetic disorders | Heart diseases
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11. Full Text Abstract 17272: Regionalization of Pediatric Cardiac Surgery Lowers Mortality, Re-operation, and Healthcare Costs
by Swartz, Michael F and Orie, Joseph and Egan, Matthew and Gensini, Francisco and Alfieris, George M
Circulation, ISSN 0009-7322, 11/2015, Volume 132, Issue Suppl_3 Suppl 3, pp. A17272 - A17272
IntroductionThe mortality of infants requiring cardiac surgery is related to center and surgeon case volume. One solution for increasing case volume is to... 
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12. Full Text Regionalization of pediatric cardiac surgery lowers mortality, re-operation, and healthcare costs
by Swartz, Michael F and Orie, Joseph and Egan, Matthew and Gensini, Francisco and Alfieris, George M
Circulation, ISSN 0009-7322, 11/2015, Volume 132, Issue 19
Heart | Care and treatment | Usage | Mortality | Analysis | Surgery | Congenital heart disease | Medical care, Cost of
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13. Full Text Distal Transverse Arch to Left Carotid Artery Ratio Helps to Identify Infants With Aortic Arch Hypoplasia
by Swartz, Michael F., PhD and Simon, Bartholomew, MD and Atallah-Yunes, Nader, MD and Cholette, Jill M., MD and Orie, Joseph, MD and Gensini, Francisco, MD and Alfieris, George M., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2015, Volume 100, Issue 3, pp. 1004 - 1012
Background Aortic coarctation (CoA) with concomitant aortic arch hypoplasia (AAH) is associated with an increased risk of hypertension after surgical repair.... 
Surgery | Cardiothoracic Surgery | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | RESECTION | RESPIRATORY SYSTEM | STRATEGY | ADVANCEMENT | COARCTATION REPAIR | OUTCOMES | EXPRESSION | CHILDREN | Aorta, Thoracic - abnormalities | Aortic Coarctation - complications | Humans | Carotid Artery, Common - anatomy & histology | Vascular Malformations - diagnosis | Female | Male | Retrospective Studies | Aorta, Thoracic - pathology | Body Weights and Measures | Infant, Newborn | Hypertension | Gene expression | Infants
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14. Full Text Elevated free hemoglobin and decreased haptoglobin levels are associated with adverse clinical outcomes, unfavorable physiologic measures, and altered inflammatory markers in pediatric cardiac surgery patients
by Cholette, Jill M and Pietropaoli, Anthony P and Henrichs, Kelly F and Alfieris, George M and Powers, Karen S and Gensini, Francisco and Rubenstein, Jeffrey S and Sweeney, Dawn and Phipps, Richard and Spinelli, Sherry L and Refaai, Majed A and Eaton, Michael P and Blumberg, Neil
Transfusion, ISSN 0041-1132, 07/2018, Volume 58, Issue 7, pp. 1631 - 1639
BACKGROUND There are data suggesting that free hemoglobin (Hb), heme, and iron contribute to infection, thrombosis, multiorgan failure, and death in critically... 
STORAGE | EXTRAVASCULAR HEMOLYSIS | THERAPY | HEME | MECHANISM | TRANSFUSION | RED-BLOOD-CELLS | SICKLE-CELL-DISEASE | HEMATOLOGY | HEMOPEXIN | CHILDREN | Hemolysis | Humans | Postoperative Period | Child, Preschool | Hemoglobins - metabolism | Infant | Male | Haptoglobins - metabolism | Thoracic Surgery | C-Reactive Protein - metabolism | CD40 Ligand - metabolism | Adolescent | Female | Child | Interleukin-6 - metabolism | Infant, Newborn | Thrombosis - therapy | Blood Transfusion - methods | Hospital patients | Pediatrics | Genetic disorders | Patient outcomes | Mortality | Congenital heart disease | Thrombosis | Blood clot | Lactates | Haptoglobin | Interleukins | Coronary artery bypass | Cardiac patients | Surgery | Heme | Hemoglobin | Children | Heart diseases | Health aspects | Heart | Nosocomial infection | Transfusion | Interleukin | Iron | Inflammation | Infections | Patients | Coronary artery disease | Clinical outcomes | Hospitals | Biomarkers | Ventilation | Lactic acid | Intubation | Nosocomial infections | Thromboembolism | RBC storage | thrombosis | congenital heart disease | cardiopulmonary bypass | cardiac surgery | transfusion | haptoglobin | hemoglobin | nosocomial infection
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15. Full Text Differing genetic expression patterns in infants with aortic coarctation with without arch hypoplasia
by Swartz, Michael F and Parikh, Pratik and Cholette, Jill M and Atallah-Yunes, Nader and Alfieris, George M
Circulation, ISSN 0009-7322, 11/2014, Volume 130, Issue 22
Hypertension | Aortic coarctation | Care and treatment | Research | Gene expression | Risk factors
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16. Full Text Pharmacokinetics of ε-Aminocaproic Acid in Neonates Undergoing Cardiac Surgery with Cardiopulmonary Bypass
by Eaton, Michael P and Alfieris, George M and Sweeney, Dawn M and Angona, Ronald E and Cholette, Jill M and Venuto, Charles and Anderson, Brian
Anesthesiology, ISSN 0003-3022, 05/2015, Volume 122, Issue 5, pp. 1002 - 1009
Background: Antifibrinolytic medications such as e-aminocaproic acid (EACA) are used in pediatric heart surgery to decrease surgical bleeding and transfusion.... 
FIBRINOLYSIS | CARBOHYDRATE SEQUENCES | IN-VITRO | INHIBITION | DRUG BIODISPOSITION | POPULATION PHARMACOKINETICS | SIZE | ANESTHESIOLOGY | PHARMACODYNAMIC INTERFACE | PRINCIPLES | CHILDREN | Antifibrinolytic Agents - pharmacokinetics | Fibrinolysis - drug effects | Infusion Pumps | Humans | Aminocaproic Acid - pharmacokinetics | Male | Cardiopulmonary Bypass | Models, Statistical | Aminocaproic Acid - pharmacology | Cardiac Surgical Procedures | Antifibrinolytic Agents - administration & dosage | Antifibrinolytic Agents - pharmacology | Female | Infusions, Intravenous | Nonlinear Dynamics | Aminocaproic Acid - administration & dosage | Infant, Newborn
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17. Full Text Damus–Kaye–Stansel procedure avoids coronary obstruction in complex D‐transposition
by Simon, Bartholomew V and Swartz, Michael F and Alfieris, George M
Journal of Cardiac Surgery, ISSN 0886-0440, 11/2018, Volume 33, Issue 11, pp. 756 - 758
Although all coronary anatomy in D‐transposition of the great arteries may be “switchable,” there are reports in the literature of early and late coronary... 
coronary artery disease | aorta and great vessels | congenital heart disease | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | ARTERIAL SWITCH OPERATION
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18. Full Text Children with single-ventricle physiology do not benefit from higher hemoglobin levels post cavopulmonary connection: Results of a prospective, randomized, controlled trial of a restrictive versus liberal red-cell transfusion strategy
by Cholette, Jill M and Rubenstein, Jeffrey S and Alfieris, George M and Powers, Karen S and Eaton, Michael and Lerner, Norma B
Pediatric Critical Care Medicine, ISSN 1529-7535, 2011, Volume 12, Issue 1, pp. 39 - 45
Objective: To examine the impact of a restrictive vs. liberal transfusion strategy on arterial lactate and oxygen content differences in children with... 
cavopulmonary connection | congenital heart disease | pediatric cardiac surgery | transfusion | lactate | hemoglobin | UNIT | CRITICALLY-ILL | MULTIPLE ORGAN FAILURE | CRITICAL-CARE | SHOCK | SERUM LACTATE | PEDIATRIC CARDIAC-SURGERY | PREDICT | BLOOD-TRANSFUSION | PEDIATRICS | ANEMIA | CRITICAL CARE MEDICINE | Lactates - blood | New York | Prospective Studies | Heart Defects, Congenital - surgery | Humans | Child, Preschool | Hemoglobins - metabolism | Infant | Intensive Care Units, Pediatric | Male | Treatment Outcome | Erythrocyte Transfusion - methods | Oxygen - blood | Heart Ventricles - abnormalities | Postoperative Care | Heart Ventricles - surgery | Female | Heart Defects, Congenital - blood
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19. Full Text Serial Follow-Up of Two Surgical Strategies for the Repair of Tetralogy of Fallot
by Simon, Bartholomew V., MD and Subramanian, Subhashini, MD and Swartz, Michael F., PhD and Wang, Hongyue, PhD and Atallah-Yunes, Nader, MD and Alfieris, George M., MD
Seminars in Thoracic and Cardiovascular Surgery, ISSN 1043-0679, 2019, Volume 31, Issue 3, pp. 515 - 523
Adverse events following tetralogy of Fallot repair include arrhythmia, reoperation, and death. While limiting the right ventriculotomy mitigates these events... 
Cardiothoracic Surgery | Tetralogy of Fallot | Ventriculotomy | Congenital heart disease | congenital heart disease | ventriculotomy
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20. Full Text Identification of differentially regulated genes in human patent ductus arteriosus
by Parikh, Pratik and Bai, Haiqing and Swartz, Michael F and Alfieris, George M and Dean, David A
Experimental Biology and Medicine, ISSN 1535-3702, 12/2016, Volume 241, Issue 18, pp. 2112 - 2118
In order to identify differentially expressed genes that are specific to the ductus arteriosus, 18 candidate genes were evaluated in matched ductus arteriosus... 
Neonatology | gene therapy | cardiovascular | gene | heart | pediatric | MEDICINE, RESEARCH & EXPERIMENTAL | PROFILES | SUSCEPTIBILITY | RATS | CLOSURE | PRETERM INFANTS | VASCULAR-TONE | SMOOTH-MUSCLE-CELLS | BIRTH | EXPRESSION | Ductus Arteriosus, Patent - genetics | Age Factors | Muscle, Smooth, Vascular - metabolism | Humans | Transcriptome | Infant | Male | Aorta - metabolism | Ductus Arteriosus, Patent - metabolism | Promoter Regions, Genetic - genetics | Promoter Regions, Genetic - physiology | Receptor, Angiotensin, Type 1 - metabolism | Female | Aorta - physiology | Infant, Newborn | Muscle, Smooth, Vascular - physiology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Original Research
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