X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry (28) 28
heterocyclic compounds (28) 28
human necessities (28) 28
hygiene (28) 28
medical or veterinary science (28) 28
metallurgy (28) 28
organic chemistry (28) 28
preparations for medical, dental, or toilet purposes (28) 28
index medicus (18) 18
biosynthesis (9) 9
specific therapeutic activity of chemical compounds ormedicinal preparations (9) 9
article (8) 8
biochemistry & molecular biology (7) 7
models, molecular (7) 7
chemistry, organic (6) 6
mutation (6) 6
structure-activity relationship (6) 6
animals (5) 5
chemistry, medicinal (5) 5
crystal-structure (5) 5
crystallography, x-ray (5) 5
fatty-acid biosynthesis (5) 5
humans (5) 5
investigating or analysing materials by determining theirchemical or physical properties (5) 5
measuring (5) 5
molecular structure (5) 5
physics (5) 5
testing (5) 5
antitumor agents (4) 4
binding sites (4) 4
biochemistry (4) 4
cell line, tumor (4) 4
gene-cluster (4) 4
kinetics (4) 4
lactones - metabolism (4) 4
ligands (4) 4
mycobacterium-tuberculosis (4) 4
pharmacology (4) 4
polyketides (4) 4
stereoisomerism (4) 4
streptomyces (4) 4
3-oxoacyl- synthase - antagonists & inhibitors (3) 3
acyl carrier protein (3) 3
agriculture (3) 3
analysis (3) 3
animal husbandry (3) 3
antifungal antibiotics phoslactomycins (3) 3
apoptosis (3) 3
biocides, e.g. as disinfectants, as pesticides, as herbicides (3) 3
cardiac amyloidosis (3) 3
cell line (3) 3
cell survival - drug effects (3) 3
chemical properties (3) 3
clinical biochemistry (3) 3
crystal structure (3) 3
drug discovery (3) 3
enzyme inhibitors - pharmacology (3) 3
enzymes (3) 3
escherichia coli - enzymology (3) 3
fabh (3) 3
fatty acid biosynthesis (3) 3
fishing (3) 3
forestry (3) 3
hunting (3) 3
molecular biology (3) 3
molecular medicine (3) 3
molecular sequence data (3) 3
molecules (3) 3
natural products (3) 3
organophosphorus compounds - metabolism (3) 3
pest repellants or attractants (3) 3
plant growth regulators (3) 3
polyketide synthases - genetics (3) 3
polyketide synthases - metabolism (3) 3
prealbumin - metabolism (3) 3
preservation of bodies of humans or animals or plants or partsthereof (3) 3
prodigiosin - analogs & derivatives (3) 3
protein binding (3) 3
protein synthase-iii (3) 3
streptomyces - enzymology (3) 3
streptomyces - genetics (3) 3
substrate specificity (3) 3
substrate-specificity (3) 3
trapping (3) 3
3-oxoacyl- synthase - chemistry (2) 2
3-oxoacyl- synthase - metabolism (2) 2
acyl coenzyme a - metabolism (2) 2
acylation (2) 2
african-americans (2) 2
alkylation (2) 2
amino acid sequence (2) 2
amyloidosis - metabolism (2) 2
amyloidosis - prevention & control (2) 2
antimalarials - pharmacology (2) 2
antineoplastic agents - chemical synthesis (2) 2
antineoplastic agents - pharmacology (2) 2
bacterial proteins (2) 2
benzoates - chemistry (2) 2
biological sciences (2) 2
carboxylic acids (2) 2
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (60) 60
French (7) 7
German (5) 5
Croatian (1) 1
Danish (1) 1
Polish (1) 1
Serbian (1) 1
Slovenian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 24, pp. 9992 - 9997
The misassembly of soluble proteins into toxic aggregates, including amyloid fibrils, underlies a large number of human degenerative diseases. Cardiac... 
Aggregation | Exchange rates | Molecules | Familial amyloidosis | Ligands | Cardiomyopathies | Amyloids | Kinetics | Monomers | Binding sites | Drug design | Crystal structure | POLYNEUROPATHY | drug design | MULTIDISCIPLINARY SCIENCES | CARDIAC AMYLOIDOSIS | VARIANT | TRANSPLANTATION | HEART | DISSOCIATION | TAFAMIDIS | DISEASE | crystal structure | AFRICAN-AMERICANS | PROTEINS | Amyloidosis - prevention & control | Benzoxazoles - pharmacology | Prealbumin - genetics | Pyrazoles - therapeutic use | Benzoates - therapeutic use | Rats, Wistar | Area Under Curve | Benzoates - chemistry | Humans | Benzoxazoles - metabolism | Cardiomyopathies - prevention & control | Crystallography, X-Ray | Dose-Response Relationship, Drug | Cardiomyopathies - genetics | Pyrazoles - chemistry | Amyloid - metabolism | MCF-7 Cells | Amyloidosis - genetics | Molecular Structure | Prealbumin - chemistry | Pyrazoles - pharmacokinetics | Protein Structure, Tertiary | Amyloid - antagonists & inhibitors | Amyloid - genetics | Cell Line | Cell Survival - drug effects | Models, Molecular | Rats | Mice, Inbred ICR | Animals | Prealbumin - metabolism | Cardiomyopathies - metabolism | Protein Stability - drug effects | Cell Line, Tumor | Protein Binding | Mice | HeLa Cells | Mutation | Amyloidosis - metabolism | Benzoates - pharmacokinetics | Benzoxazoles - pharmacokinetics | Proteins | Heart | African Americans | Cytotoxicity | Cells | Index Medicus | Biological Sciences
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2008, Volume 130, Issue 37, pp. 12236 - 12237
The antifungal phoslactomycins (PLM A-F), produced by Streptomyes sp HK803, are structurally unusual in that three of their four double bonds are in the cis... 
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 10/2015, Volume 11, Issue 10, pp. 793 - 798
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 07/2009, Volume 106, Issue 30, pp. 12295 - 12300
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2008, Volume 130, Issue 37, p. 12236
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2011, Volume 3, Issue 97
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 2019, Volume 16, Issue 7, pp. 3237 - 3252
The hydrophobicity of many chemotherapeutic agents usually results in their nonselective passive distribution into healthy cells and organs causing collateral... 
PSMA ligands | half-life extension | targeted chemotherapeutic agents | prostate cancer | hydrophilic transthyretin ligands | THERAPEUTICS | MEDICINE, RESEARCH & EXPERIMENTAL | MEMBRANE ANTIGEN | ANTIBODY | PENETRATION | PSMA | POTENT | ALPHA(V)BETA | LIGANDS | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | EXPRESSION
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2009, Volume 5, Issue 4, pp. P429 - P430
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2007, Volume 129, Issue 7, pp. 1910 - 1911
Journal Article
Journal Article
Synthesis, ISSN 0039-7881, 11/2007, Volume 2007, Issue 22, pp. 3512 - 3518
Journal Article
Journal Article
Chemistry (Weinheim an der Bergstrasse, Germany), ISSN 0947-6539, 2008, Volume 14, Issue 2, pp. 570 - 581
Stereoselective total syntheses of two novel conformationally restrained epothilone analogues are described. Evans asymmetric alkylation, Brown allylation, and... 
natural products | total synthesis | antitumor agents | epothilone analogues | macrolide
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.