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Trends in Molecular Medicine, ISSN 1471-4914, 2012, Volume 18, Issue 10, pp. 615 - 625
Crohn's disease and ulcerative colitis are two major forms of inflammatory bowel diseases (IBD), which are chronic inflammatory disorders of the... 
Pathology | monoacylglycerol lipase | fatty acid amide hydrolase | palmitoylethanolamide | N-arachidonoylethanolamine | endocannabinoids | anandamide | inflammatory bowel disease | 2-arachidonoylglycerol | Inflammatory bowel disease | Monoacylglycerol lipase | Palmitoylethanolamide | Fatty acid amide hydrolase | Endocannabinoids | Anandamide | DEXTRAN SULFATE SODIUM | MEDICINE, RESEARCH & EXPERIMENTAL | CROHNS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ULCERATIVE-COLITIS | MOUSE COLON | CELL BIOLOGY | EXPERIMENTAL COLITIS | LIPOPOLYSACCHARIDE-TREATED RATS | CANNABINOID RECEPTOR AGONISTS | GASTROINTESTINAL MOTILITY | INTESTINAL PERMEABILITY | CB1 RECEPTORS | Amidohydrolases - metabolism | Inflammatory Bowel Diseases - drug therapy | Endocannabinoids - pharmacology | Humans | Gastrointestinal Tract - physiopathology | Gastrointestinal Tract - drug effects | Inflammatory Bowel Diseases - physiopathology | Cannabinoid Receptor Agonists - pharmacology | Arachidonic Acids - pharmacology | Gastrointestinal Tract - metabolism | Receptors, Cannabinoid - drug effects | Receptors, Cannabinoid - metabolism | Monoacylglycerol Lipases - metabolism | Glycerides - pharmacology | Animals | Inflammation - drug therapy | Polyunsaturated Alkamides - pharmacology | Homeostasis - drug effects | Disease Models, Animal | Inflammation - physiopathology | Analysis | Gastrointestinal system | Physiological aspects | Crohn's disease | Lipase | Fatty acids | Health aspects | Ulcerative colitis
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 43, pp. 17558 - 17563
Proinflammatory macrophages are key mediators in several pathologies; thus, controlling their activation is necessary. The endocannabinoid system is implicated... 
Enzymes | Receptors | Antiinflammatories | Messenger RNA | Cell lines | Macrophage activation | Inflammation | Macrophages | Endocannabinoids | Cannabinoid receptors | FAAH | Glyceryl prostaglandin | COX-2 | Anandamide | Prostaglandin synthase | prostaglandin synthase | CELLS | MONOACYLGLYCEROL LIPASE | 2-ARACHIDONYL GLYCEROL | MULTIDISCIPLINARY SCIENCES | ARACHIDONIC-ACID | INTERNATIONAL-UNION | CANNABINOID RECEPTORS | ENDOCANNABINOID 2-ARACHIDONOYLGLYCEROL | ACID AMIDE HYDROLASE | glyceryl prostaglandin | INHIBITORS | BLOCKADE | anandamide | Endocannabinoids - metabolism | Inflammation - chemically induced | Endocannabinoids - pharmacology | Gene Expression - drug effects | Monoacylglycerol Lipases - antagonists & inhibitors | Male | Interleukin-1beta - genetics | Monoacylglycerol Lipases - genetics | Monoacylglycerol Lipases - metabolism | Arachidonic Acids - metabolism | Inflammation - metabolism | Biphenyl Compounds - pharmacology | Cyclooxygenase 2 - genetics | Esters - chemistry | Interleukin-1beta - metabolism | Lipocalins - genetics | Prostaglandin D2 - metabolism | Female | Glycerol - chemistry | Intramolecular Oxidoreductases - metabolism | Carbamates - pharmacology | Lipocalins - metabolism | Cell Line | Lipopolysaccharides - toxicity | Enzyme-Linked Immunosorbent Assay | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Glycerides - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Arachidonic Acids - pharmacology | Prostaglandin D2 - chemistry | Glycerides - pharmacology | Macrophages - metabolism | Animals | Anti-Inflammatory Agents - chemistry | Intramolecular Oxidoreductases - genetics | Cyclooxygenase 2 - metabolism | Macrophages - drug effects | Inflammation - prevention & control | Mice | Prostaglandin D2 - pharmacology | Macrophage Activation - drug effects | Prostaglandins | Physiological aspects | Lipid metabolism | Research | Health aspects | Biological Sciences
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 08/2011, Volume 25, Issue 8, pp. 2711 - 2721
Inflammatory bowel diseases (IBDs) are chronic inflammatory conditions for which new therapeutic approaches are needed. Genetic and pharmacological data point... 
Fatty acid amide hydrolase | Lipopolysaccharide | Monoacylglycerol lipase | Endocannabinoid | Anandamide | monoacylglycerol lipase | endocannabinoid | CANNABINOID RECEPTOR 2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | ULCERATIVE-COLITIS | ENDOCANNABINOID SYSTEM | GUT MICROBIOTA | BOWEL-DISEASE | CELL BIOLOGY | fatty acid amide hydrolase | ACID AMIDE HYDROLASE | ALPHA PRODUCTION | BIOLOGY | ANTAGONIST RIMONABANT | lipopolysaccharide | anandamide | INTESTINAL PERMEABILITY | Inflammation - pathology | Endotoxemia - prevention & control | Monoacylglycerol Lipases - antagonists & inhibitors | Humans | Colitis - pathology | Male | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Arachidonic Acids - metabolism | Inflammation - metabolism | Piperidines - pharmacology | Colitis - chemically induced | Indoles - pharmacology | Endocannabinoids | Disease Models, Animal | Pyrazoles - pharmacology | Inflammatory Bowel Diseases - drug therapy | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Inflammation Mediators - blood | Glycerides - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Colitis - metabolism | Inflammation - prevention & control | Mice | Trinitrobenzenesulfonic Acid - toxicity | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Colitis - prevention & control | Benzodioxoles - pharmacology
Journal Article
Drug Discovery Today, ISSN 1359-6446, 10/2014, Volume 19, Issue 10, pp. 1632 - 1639
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2019, Volume 176, Issue 10, pp. 1470 - 1480
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 05/2019, Volume 1864, Issue 5, p. 609
Pain is one of the cardinal signs of inflammation and is present in many inflammatory conditions. Therefore, anti-inflammatory drugs such as NSAIDs also have... 
Glycerin | COX-2 inhibitors | Prostaglandins | Care and treatment | Carrageenin | Pain | Metabolites | Analysis | Glycerol | Lipids | Inflammation
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 06/2018, Volume 39, Issue 6, pp. 586 - 604
Lysophosphatidylinositols (LPIs) are membrane constituents that alter the properties of said membranes. However, recent data showing that the once orphan... 
LARGE HEAD GROUPS | SIGNALING PATHWAYS | CANNABINOID RECEPTOR | L-ALPHA-LYSOPHOSPHATIDYLINOSITOL | PROTEIN-COUPLED RECEPTOR | POSSIBLE INVOLVEMENT | INTRACELLULAR CALCIUM | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | AGONIST LYSOPHOSPHATIDYLINOSITOL | POTENTIAL ROLE
Journal Article